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Low levels of vitamin D linked to muscle fat, decreased strength in young people
McGill University Health Centre ^ | Mar 5, 2010 | Unknown

Posted on 03/05/2010 9:35:58 AM PST by decimon

There’s an epidemic in progress, and it has nothing to do with the flu. A ground-breaking study published in the March 2010 Journal of Clinical Endocrinology and Metabolism found an astonishing 59 per cent of study subjects had too little Vitamin D in their blood. Nearly a quarter of the group had serious deficiencies (less than 20 ng/ml) of this important vitamin. Since Vitamin D insufficiency is linked to increased body fat, decreased muscle strength and a range of disorders, this is a serious health issue.

“Vitamin D insufficiency is a risk factor for other diseases,” explains principal investigator, Dr. Richard Kremer, co-director of the Musculoskeletal Axis of the Research Institute of the MUHC. “Because it is linked to increased body fat, it may affect many different parts of the body. Abnormal levels of Vitamin D are associated with a whole spectrum of diseases, including cancer, osteoporosis and diabetes, as well as cardiovascular and autoimmune disorders.”

The study by Dr. Kremer and co-investigator Dr. Vincente Gilsanz, head of musculoskeletal imaging at the Children’s Hospital Los Angeles of the University of Southern California, is the first to show a clear link between Vitamin D levels and the accumulation of fat in muscle tissue – a factor in muscle strength and overall health. Scientists have known for years that Vitamin D is essential for muscle strength. Studies in the elderly have showed bedridden patients quickly gain strength when given Vitamin D.

The study results are especially surprising, because study subjects – all healthy young women living in California – could logically be expected to benefit from good diet, outdoor activities and ample exposure to sunshine – the trigger that causes the body to produce Vitamin D.

(Excerpt) Read more at muhc.ca ...


TOPICS: Health/Medicine
KEYWORDS: d3; health; nutrition; vitamind; vitd3
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1 posted on 03/05/2010 9:35:59 AM PST by decimon
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To: neverdem; DvdMom

Young punks ping.


2 posted on 03/05/2010 9:36:38 AM PST by decimon
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To: decimon

Soft Canadians ping.


3 posted on 03/05/2010 9:39:07 AM PST by 9YearLurker
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To: decimon

I remember reading that a deficiency of vitamin E results in vitamin D oxidizing, thereby resulting in a deficiency of vitamin D.


4 posted on 03/05/2010 9:44:04 AM PST by aimhigh
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To: decimon; STARWISE

Vitamin D ping!


5 posted on 03/05/2010 9:46:39 AM PST by maggief
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To: 9YearLurker
Soft Canadians ping.

Heh Heh, not this time.

study subjects – all healthy young women living in California

6 posted on 03/05/2010 9:48:39 AM PST by Trailerpark Badass (One good thing about music, when it hits you feel no pain.)
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To: decimon
The sunlight hurts us.


7 posted on 03/05/2010 9:50:05 AM PST by The_Victor (If all I want is a warm feeling, I should just wet my pants.)
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To: decimon
Keeping kids inside the classroom all day doesn't help. And while they do get summers off, just 20 minutes in the summer sun is enough to deplete all the cholesterol in the skin necessary for the production of D.

Really, kids, and adults for that matter, should be spending much more time outside in the spring and fall.

I'd think it would be great if April and October were spring and fall breaks for school kids -- at least in the more southern states.

8 posted on 03/05/2010 9:51:45 AM PST by GeorgeSaden
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To: GeorgeSaden

D-R-I-N-K-Y-O-U-R-O-V-A-L-T-I-N-E


9 posted on 03/05/2010 9:56:55 AM PST by massgopguy (I owe everything to George Bailey)
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To: Trailerpark Badass

I hate to get shown up for not reading the article!


10 posted on 03/05/2010 9:57:48 AM PST by 9YearLurker
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To: Trailerpark Badass

Soft Californians ping!


11 posted on 03/05/2010 9:58:26 AM PST by 9YearLurker
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To: decimon

Vitamin D. From the Sun. But the cancer scares have instructed young America to limit Sun exposure.


12 posted on 03/05/2010 9:59:25 AM PST by a fool in paradise
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To: a fool in paradise
Vitamin D. From the Sun.

Been around that block a few times. I think the bottom line is that, in the US, it is difficult-to-impossible to get enough vitamin D producing sunlight north of south Florida.

13 posted on 03/05/2010 10:08:13 AM PST by decimon
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To: a fool in paradise

Too much time in front of the XBox, Internet, and boob tube.


14 posted on 03/05/2010 10:33:43 AM PST by RockyMtnMan
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To: RockyMtnMan

The internetz is/are the boob tube now.


15 posted on 03/05/2010 10:35:08 AM PST by a fool in paradise
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To: GeorgeSaden

“...just 20 minutes in the summer sun is enough to deplete all the cholesterol in the skin necessary for the production of D.”

I don’t understand that statement.


16 posted on 03/05/2010 10:36:31 AM PST by Magic Fingers
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To: decimon

Depends on your ancestry. If a population is in a given area for more than about 500 years, the general skin tone of that population adjusts to maximize vit D production while minimizing skin damage, for the available sunlight in that area. There’s actually a mathematical formula somewhere for skin tone and average yearly sunlight. The exception is Inuit populations, who have historically gotten most of their vit D from fatty fish.

So, those of us whose ancestors came from northern latitudes are better adapted for living in the northern states. Provided we actually get out in the sun once in a while :p

This may have been a contributing factor for why black slavery wasn’t as predominant in the northernmost areas of North America or Europe. While I was doing research on this, I came across reports of African slaves imported to England, getting sick and dying rather quickly. The reports are centuries old so its hard to be sure, but I’m hypothesizing here that they suffered severe vitamin D deficiencies, which made them quite vulnerable to a number of things. Combine that with diseases they’d never encountered, they probably didn’t stand much of a chance.

All theory, of course. My time machine’s in the shop :p


17 posted on 03/05/2010 10:39:38 AM PST by Ellendra (Can't starve us out, and you can't make us run. . . -Hank Jr.)
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To: Magic Fingers
“...just 20 minutes in the summer sun is enough to deplete all the cholesterol in the skin necessary for the production of D.”

I don’t understand that statement.


Cholesterol is what the skin uses to make vitamin D. Its kinda cool, really. The two molecules are the same except for the position of a single bond, but they have such different effects.

Cholesterol:


Vitamin D:



18 posted on 03/05/2010 10:48:05 AM PST by Ellendra (Can't starve us out, and you can't make us run. . . -Hank Jr.)
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To: Ellendra
So, those of us whose ancestors came from northern latitudes are better adapted for living in the northern states. Provided we actually get out in the sun once in a while :p

"Sun exposure Most people meet their vitamin D needs through exposure to sunlight [5,31]. Ultraviolet (UV) B radiation with a wavelength of 290-315 nanometers penetrates uncovered skin and converts cutaneous 7-dehydrocholesterol to previtamin D3, which in turn becomes vitamin D3 [9,32,33]. Season, geographic latitude, time of day, cloud cover, smog, skin melanin content, and sunscreen are among the factors that affect UV radiation exposure and vitamin D synthesis [33]. The UV energy above 42 degrees north latitude (a line approximately between the northern border of California and Boston) is insufficient for cutaneous vitamin D synthesis from November through February [5]; in far northern latitudes, this reduced intensity lasts for up to 6 months. In the United States, latitudes below 34 degrees north (a line between Los Angeles and Columbia, South Carolina) allow for cutaneous production of vitamin D throughout the year [27]."

http://ods.od.nih.gov/factsheets/vitamind.asp

19 posted on 03/05/2010 10:56:47 AM PST by decimon
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To: Ellendra

“Cholesterol is what the skin uses to make vitamin D.”

I’m aware of that (zoology major, chemistry minor, postgraduate research in molecular biology and genetics). What I don’t understand is his statement that “20 minutes in the summer sun is enough to deplete all the cholesterol in the skin necessary for the production of D”, and then he goes on to encourage more sun exposure. That’s contradictory.


20 posted on 03/05/2010 11:09:26 AM PST by Magic Fingers
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To: decimon

Vitamin D is not a vitamin at all — in its active form it is the most powerful steroid hormone in our bodies.

Vitamin D isn’t even a nutrient! It comes from the sun, not from nutrition!

When human skin is exposed to sufficiently powerful ultraviolet (UV) radiation from sunlight, a form of cholesterol contained in our skin (“7-dehydrocholesterol”) is converted into the precursor of Vitamin D, called “cholecalciferol”. This is then converted by our liver into the inactive bulk storage form of vitamin D that blood tests measure (“25-hydroxyvitamin D”). Although Vitamin D is present in limited amounts in cod liver oil and some fatty fish (salmon, mackerel and tuna), it is essentially unavailable in metabolically useful quantities from dietary sources.

As we age, our skin gradually loses its youthful cholesterol and its ability to synthesize Vitamin D declines over time. Although it has not been widely studied, some reports indicate that by the age of 50, Vitamin D production has fallen to approximately 50% of its original rate, and by the age of 65 production will have fallen to just 25% of its original capability. And independent of age, the skin’s melanin pigmentation — either from natural genetic racial coloration or tanning adaptation — acts to absorb much of the sun’s visible and ultraviolet radiation. This skin darkening has the beneficial effect of protecting our skin from UV radiation damage, but at the expense of further reducing the skin’s rate and capacity for Vitamin D production. (Melanin is 99.9% efficient in absorbing the energy from ultraviolet light, converting it into harmless heat energy.)

I ran into this a while back, and I got to thinking about it, since I take 1000 IU Vit D a day. My sleep patterns have improved, so has, I feel, my memory.

I was thinking that computers have caused me to stay indoors too much, and I’m not getting the Sun’s effects.


21 posted on 03/05/2010 11:28:38 AM PST by papasmurf (sudo apt-get install U-S-Constitution)
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To: decimon

“...it is difficult-to-impossible to get enough vitamin D producing sunlight north of south Florida.”

My understanding is that you don’t need the direct sunlight, just the rays from the Sun, which is abundant, even on cloudy days?


22 posted on 03/05/2010 11:30:49 AM PST by papasmurf (sudo apt-get install U-S-Constitution)
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To: papasmurf
I ran into this a while back, and I got to thinking about it, since I take 1000 IU Vit D a day.

1000IU daily seems to be the new minimum recommended amount. For adults, that is.

23 posted on 03/05/2010 11:33:14 AM PST by decimon
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To: decimon

A friend of my Wife’s, says I should be taking 1600. But, D becomes toxic at about 50,000 in a Month’s time, right?

I’m looking to see where I got that piece of the article I posted above, it was really helpful, but I just saved it as a text file. {oops}


24 posted on 03/05/2010 11:38:22 AM PST by papasmurf (sudo apt-get install U-S-Constitution)
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To: papasmurf
My understanding is that you don’t need the direct sunlight, just the rays from the Sun, which is abundant, even on cloudy days?

My understanding is quite the opposite. You need UVB light which is blocked by clouds and by glass.

See post #19. The reason you can't make vitamin D in the winter, at higher latitudes, is that the Sun is low to the horizon. At that attitude the atmosphere blocks UVB. Think about it and that would apply to the early and late hours even in the summertime.

The info in post #19 made me think about how much beneficial sunlight I actually get and I decided that I don't get much. So I supplement.

25 posted on 03/05/2010 11:40:36 AM PST by decimon
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To: decimon
Dr. Lowdog (native American Indian) says that most people in the USA are probably deficient in Vitamin D, and should take supplements. The doctor also states that it is a factor in osteoporosis(as well as other problems), but many doctors do not even bother to test for the deficiency.

I started taking supplements about 2 years ago, and have felt a lot better, and did not get the flu or colds since then, although I did get a sore throat and runny nose which lasted for 1 day.

I used to get several colds that lasted for a couple of weeks. Maybe it's the placebo effect, but I intend to keep taking the supplements.

26 posted on 03/05/2010 11:44:31 AM PST by greeneyes (Moderation in defense of your country is NO virtue. Let Freedom Ring.)
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To: decimon; All

If John McCain gets his way, you won’t be able to buy Vit. D or anything else without his say so!

Pop Quiz: Which D.C. Politician Wants to Takeover Your Vitamins?
http://www.freerepublic.com/focus/f-news/2464287/posts


27 posted on 03/05/2010 11:44:46 AM PST by AuntB (WE are NOT a nation of immigrants! We're a nation of Americans! http://towncriernews.blogspot.com/)
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To: decimon

Oh, goodie. I’m at 33.11 deg! Now all I have to do is... more yardwork. LOL


28 posted on 03/05/2010 11:46:44 AM PST by papasmurf (sudo apt-get install U-S-Constitution)
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To: papasmurf
A friend of my Wife’s, says I should be taking 1600. But, D becomes toxic at about 50,000 in a Month’s time, right?

I've been taking 7,000IU a day for some months so I think my bones would by now be dust if 50,000IU a month would do it.

But you are asking for specific advice I'm not qualified to give. I post a lot of these articles for informational purposes but I'm simply not qualified to give medical advice.

29 posted on 03/05/2010 11:51:31 AM PST by decimon
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To: decimon
Vitamin D Status and Its Relation to Muscle Mass and Muscle Fat in Young Women
30 posted on 03/05/2010 11:51:35 AM PST by neverdem (Xin loi minh oi)
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To: AuntB
If John McCain gets his way, you won’t be able to buy Vit. D or anything else without his say so!

Yeah, McCain. You never know what he might do.

31 posted on 03/05/2010 11:54:23 AM PST by decimon
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To: papasmurf
Now all I have to do is... more yardwork.

Gave that some thought, too. In the winter you might have some minutes a day of beneficial sunlight. You'd have to have a sunny day and be able to catch that short window when the sun is highest in the sky.

32 posted on 03/05/2010 11:57:24 AM PST by decimon
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To: neverdem

Fat bottomed girls.


33 posted on 03/05/2010 11:59:23 AM PST by decimon
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To: Magic Fingers

Ah, ok.


34 posted on 03/05/2010 12:54:11 PM PST by Ellendra (Can't starve us out, and you can't make us run. . . -Hank Jr.)
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To: Magic Fingers
I don’t understand that statement.

The body is supplied naturally with vitamin D by the conversion of cholesterol in the skin to vitamin D by ultraviolet light of the sun.

Cholesterol moves slowly into the skin, though, so after just 20 minutes exposed to the ultraviolet light of the full summer sun, all the available cholesterol has been converted to D.

Spring and fall sunlight contains less ultraviolet light, though, so it makes sense to get more sun in the spring and fall.

35 posted on 03/05/2010 1:08:27 PM PST by GeorgeSaden
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To: GeorgeSaden

“Spring and fall sunlight contains less ultraviolet light, though, so it makes sense to get more sun in the spring and fall.”

In the reading I’ve done about Vitamin D I’ve never seen that recommendation, including numerous Vitamin D Council newsletters (John Cannell, M.D.). In fact, the recommendations all point to summer sun as the best for Vitamin D stimulation due to the decreased angle of incidence and resultant increase in ultraviolet energy. Of course, I may have missed it...I’d be interested in any links or studies you might have regarding spring and fall being better for Vitamin D generation.


36 posted on 03/05/2010 3:33:34 PM PST by Magic Fingers
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To: neverdem; maggief; onyx; Bahbah; SE Mom; LUV W; Allegra; All

I take between 4-8K a day. I know an anti-
aging doc. He takes 20K a day if he’s
fighting a cold. Says it’s not toxic at
that dose .. in fact, many anti-aging docs
believe it’s not toxic until you get to
around 50K a day level.

He says the current recommended adult dose
is 5K a day.

Two friends of mine have had to take 50K a
week for almost 2 months, they were so deficient.

I’m a big believer, but as always: do your own
due diligence.


37 posted on 03/05/2010 3:38:13 PM PST by STARWISE (They (LIBS-STILL) think of this WOT as Bush's war, not America's war- Richard Miniter)
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To: papasmurf

Well, that settles it. Tomorrow afternoon, I’m taking a book and a chair to the back yard. It’s supposed to be nice and sunny.


38 posted on 03/05/2010 3:38:48 PM PST by Desdemona
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To: decimon; papasmurf; maggief; All

Previous FR thread

The vitamin D miracle: Is it for real?
http://www.freerepublic.com/focus/f-news/2401559/posts


39 posted on 03/05/2010 3:40:12 PM PST by STARWISE (They (LIBS-STILL) think of this WOT as Bush's war, not America's war- Richard Miniter)
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To: STARWISE
I started taking 2K a day after I got H1N1 in October and have been cold and flu-free since.

Plus, I tend to live in sunny areas and enjoy being out in the sun and I soak some D up that good ol' natural way.

40 posted on 03/05/2010 4:19:23 PM PST by Allegra (It doesn't matter what this tagline says...the liberals are going to call it "racist.")
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To: STARWISE

Thanks. I remember that thread.


41 posted on 03/05/2010 4:40:29 PM PST by decimon
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To: STARWISE

I’m a believer, thanks to you.


42 posted on 03/05/2010 6:42:21 PM PST by onyx (BE A MONTHLY DONOR - I AM)
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To: Magic Fingers
Of course, I may have missed it...I’d be interested in any links or studies you might have regarding spring and fall being better for Vitamin D generation.

I didn't mean to imply that more D can be created in spring and fall. It's more difficult to get Vitamin D during the spring and fall which is precisely why it's important to spend more time outside during those times of year. In the summer it's very easy to get enough D. For school children a 20 minute recess outside in June would be enough. But it takes longer during spring and fall to get the same amount of D. What I propose is allowing children to have month long spring and fall breaks from school so that they may spend more time outside during those times of year when D is harder to make. And of course skin must be exposed. Temperatures in spring and fall in the middle of the day are often warm enough to permit short sleeve shirts and short pants.

Winter is more difficult, of course, though for me I've created a special sitting area shielded from the wind that allows me to sun some days in winter when the sky is clear.

43 posted on 03/05/2010 8:07:17 PM PST by GeorgeSaden
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To: GeorgeSaden

10-4, thanks for the clarification.


44 posted on 03/05/2010 8:15:00 PM PST by Magic Fingers
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To: musicman

BFLR


45 posted on 03/05/2010 9:20:36 PM PST by musicman (Until I see the REAL Long Form Vault BC, he's just "PRES__ENT" Obama = Without "ID")
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To: decimon; AdmSmith; Berosus; bigheadfred; Convert from ECUSA; dervish; Ernest_at_the_Beach; ...
A ground-breaking study published in the March 2010 Journal of Clinical Endocrinology and Metabolism found an astonishing 59 per cent of study subjects had too little Vitamin D in their blood.
I had the same problem, only I'm not, uh, in that demographic. Been taking D3 and Niacin (doctor said to), and feel better. Still fat though.
46 posted on 03/05/2010 10:06:29 PM PST by SunkenCiv (Freedom is Priceless.)
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To: SunkenCiv

Freepmail coming.


47 posted on 03/06/2010 4:57:28 AM PST by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: decimon

I take 50000IU twice a week.


48 posted on 03/06/2010 4:58:47 AM PST by bmwcyle (Free the Navy Seals)
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To: decimon; 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...

Vitamin D article ping , thanks again freeper decimon :)


49 posted on 03/06/2010 6:17:41 AM PST by DvdMom (Freeper Smokin' Joe does the freeper Avian / H1N1 Ping List)
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To: DvdMom

You are again welcome, DvdMom.


50 posted on 03/06/2010 6:21:18 AM PST by decimon
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