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Stem Cells Help British Boy Grow New Windpipe
FOXNews.com ^ | Saturday, March 20, 2010 | Foxnews.com

Posted on 03/20/2010 9:03:25 AM PDT by metmom

A British boy successfully underwent a groundbreaking operation involving the transplant of a windpipe which is being regenerated inside his body using his own stem cells, The Times of London reported Saturday.

Scientists described the operation, carried out on Monday at London's Great Ormond Street Hospital, as a "milestone moment" in the development of techniques that could allow people to rebuild damaged or transplanted organs inside their bodies.

The replacement trachea - the bony tube that connects the nose, mouth and lungs - was stripped of the donor's cells to leave a scaffold which was then laced with the child's stem cells. The boy, aged 10, then received the transplant hours later. The stem cells are now reconstructing the airway and ensuring it is not rejected by his immune system.

(Excerpt) Read more at foxnews.com ...


TOPICS: Health/Medicine; Miscellaneous; Science
KEYWORDS: prolife; stemcells; windpipe

1 posted on 03/20/2010 9:03:25 AM PDT by metmom
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To: neverdem; wagglebee; little jeremiah

Another nail in the coffin for embryonic stem cell research.

It’s simply not justifiable.


2 posted on 03/20/2010 9:04:19 AM PDT by metmom (Welfare was never meant to be a career choice.)
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To: metmom

Fantastic! Let’s use more stem cells but just not embryonic.


3 posted on 03/20/2010 9:04:33 AM PDT by napscoordinator
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To: metmom

And to imagine there are troglodytes out there who are against the use of embryonic stem cells for this kind of groundbreaking research. /s


4 posted on 03/20/2010 9:21:55 AM PDT by skeeter
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To: metmom

Cool. How does this happen under the UK’s NHS?


5 posted on 03/20/2010 9:27:51 AM PDT by Paladin2
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To: metmom

This is amazing. I’m so glad that I saved the cord blood from all of my children. Thanks metmom for posting.


6 posted on 03/20/2010 9:28:30 AM PDT by AngieGal
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To: metmom

Amazing. Does this mean the boy will not have to take immune suppressant drugs for his whole life?


7 posted on 03/20/2010 9:51:00 AM PDT by little jeremiah (Asato Ma Sad Gamaya Tamaso Ma Jyotir Gamaya)
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To: metmom

Thanks for the ping.


8 posted on 03/20/2010 10:34:19 AM PDT by neverdem (Xin loi minh oi)
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To: little jeremiah
Does this mean the boy will not have to take immune suppressant drugs for his whole life?

From the original article in the Times of London:

The use of the child’s own stem cells inside his body to build up the donor windpipe ensures that it is not rejected by his immune system. With a normal transplant, the risk of rejection would mean “damping down” the child’s immune system with suppressive drugs.

So, it sounds like those drugs won't be needed here, which is awesome.

9 posted on 03/20/2010 10:58:07 AM PDT by BlessedBeGod (New Wizard of Oz: Pelosi as the Wicked Witch of the West & Michelle as the Wicked Witch of the East.)
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To: metmom
"...inside his body using his own stem cells..."

Nice try of BIG Journalism to avoid mentioning this important fact in their title.

10 posted on 03/20/2010 11:00:25 AM PDT by newfreep (Palin/DeMint 2012 - Bolton: Secy of State)
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To: newfreep

Yay! More adult stem cell success stories!


11 posted on 03/20/2010 11:05:01 AM PDT by BenKenobi (And into this Ring he poured his cruelty, his malice and his will to dominate all life.)
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To: Paladin2
How does this happen under the UK’s NHS?

Nazis made a lot of scientific progress too, at a high human cost.

12 posted on 03/20/2010 11:24:09 AM PDT by Clock King (There's no way to fix D.C.)
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To: metmom; GonzoII; Coleus; Peach; airborne; Asphalt; Dr. Scarpetta; I'm ALL Right!; StAnDeliver; ...
regenerative medicine ping

Woman Gets New Windpipe Using Her Own Stem Cells (WOW!) Here's the old thread about Claudia Castillo.

'Milestone moment' as boy undergoes transplant to regenerate trachea Here's the Timesonline version of the new story.

13 posted on 03/20/2010 11:44:05 AM PDT by neverdem (Xin loi minh oi)
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To: Paladin2

PR?


14 posted on 03/20/2010 11:46:09 AM PDT by metmom (Welfare was never meant to be a career choice.)
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To: little jeremiah

That’s what the article says. If it’s his own cells, then there’s no risk of rejection.


15 posted on 03/20/2010 11:47:07 AM PDT by metmom (Welfare was never meant to be a career choice.)
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To: neverdem
Help me understand this.

They grew a whole new windpipe, or they regrew his?

Or did they use a partial transplant and augment it with his own stem cells?

No matter what, this is wonderful news!!

16 posted on 03/20/2010 11:47:22 AM PDT by airborne ("Peace, Love, Dope" has now become "Hope, Change, Obama" !!!)
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To: airborne
Or did they use a partial transplant and augment it with his own stem cells?

That's what I read it as.

They made some kind of framework, like a structural skeleton, and added his own stem cells which will adhere to and grow on the structure.

17 posted on 03/20/2010 11:49:28 AM PDT by metmom (Welfare was never meant to be a career choice.)
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To: metmom

Amazing!!!


18 posted on 03/20/2010 12:05:31 PM PDT by airborne ("Peace, Love, Dope" has now become "Hope, Change, Obama" !!!)
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To: metmom

I wasn’t sure since it sounded as though part of it came from someone else.

This is excellent news. Harmless medicine.


19 posted on 03/20/2010 12:11:16 PM PDT by little jeremiah (Asato Ma Sad Gamaya Tamaso Ma Jyotir Gamaya)
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To: airborne; metmom
"The replacement trachea - the bony tube that connects the nose, mouth and lungs - was stripped of the donor's cells to leave a scaffold which was then laced with the child's stem cells."

They probably soak the donor trachea in a solution of proteases, enzymes that dissolve proteins, to remove any antigens so as not to provoke an attack with antibodies or other elements of the immune system. The scaffold is probably just decellularized hyaline cartilege, IMHO.

20 posted on 03/20/2010 12:47:18 PM PDT by neverdem (Xin loi minh oi)
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To: little jeremiah
I wasn’t sure since it sounded as though part of it came from someone else.

It did, probably a trauma victim.

21 posted on 03/20/2010 12:52:05 PM PDT by neverdem (Xin loi minh oi)
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To: neverdem

Thanks. The article wasn’t very clear about that and I didn’t know that they could do that.


22 posted on 03/20/2010 2:57:35 PM PDT by metmom (Welfare was never meant to be a career choice.)
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To: metmom
Pinged from Terri Dailies


23 posted on 03/21/2010 10:14:51 AM PDT by wagglebee ("A political party cannot be all things to all people." -- Ronald Reagan, 3/1/75)
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