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Vitamin D deficiency common in cancer patients
American Society for Radiation Oncology ^ | October 3, 2011 | Unknown

Posted on 10/03/2011 11:45:22 AM PDT by decimon

Predicts advanced disease

Miami Beach, Fla., October 2, 2011 – More than three-quarters of cancer patients have insufficient levels of vitamin D (25-hydroxy-vitamin D) and the lowest levels are associated with more advanced cancer, according to a study presented on October 2, 2011, at the 53rd Annual Meeting of the American Society for Radiation Oncology (ASTRO).

"Until recently, studies have not investigated whether vitamin D has an impact on the prognosis or course of cancer. Researchers are just starting to examine how vitamin D may impact specific features of cancer, such as the stage or extent of tumor spread, prognosis, recurrence or relapse of disease, and even sub-types of cancer," Thomas Churilla, lead author of the study and a medical student at the Commonwealth Medical College, Scranton, Pa., said.

>

Patients who were found to be vitamin D deficient were administered replacement therapy, increasing serum D levels by an average of 14.9 ng/mL. Investigators will be analyzing if vitamin D supplementation had an impact on aspects of treatment or survival in the long-term.

>

(Excerpt) Read more at eurekalert.org ...


TOPICS: Health/Medicine; Science
KEYWORDS: cancer; health; medicine; vitamind; vitamins

1 posted on 10/03/2011 11:45:24 AM PDT by decimon
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To: decimon

It would be tragic, but hardly surprising, if we found out clinically that even skin cancer was boosted by low vitamin D levels....


2 posted on 10/03/2011 11:49:28 AM PDT by ConservativeDude
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To: decimon

It would be tragic, but hardly surprising, if we found out clinically that even skin cancer was boosted by low vitamin D levels....


3 posted on 10/03/2011 11:49:27 AM PDT by ConservativeDude
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To: ConservativeDude

Living in Seattle, my doctors always have me on vitamin D or it gets low. Don’t see the sun enough. People always take things to extremes. If too much sun is a bad thing, they think no sun must be better. Not so.


4 posted on 10/03/2011 11:52:36 AM PDT by Cherokee Conservative (If a tree falls over in the woods, and then snaps back upright as a joke, do the squirrels laugh?)
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To: decimon

Because of the NEW standards almost EVERYONE is deficient in Vit D


5 posted on 10/03/2011 11:53:22 AM PDT by RnMomof7
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To: decimon

Because of the NEW standards almost EVERYONE is deficient in Vit D


6 posted on 10/03/2011 11:53:36 AM PDT by RnMomof7
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To: decimon

This may have absolutely nothing to do with this subject but I remember when my Dad was first diagnosed as terminal. He had huge cravings for two things... milk and apples. He literally would drink a gallon of milk a day and eat four to five apples. (This craving was even before the diagnosis as well). Prior to that, he would eat an apple on occasion and I don’t remember him ever drinking milk. Now I am wondering if it was the Vitamin D (in the milk). I am still confused over the apples but maybe they will find a link to that eventually?


7 posted on 10/03/2011 11:57:03 AM PDT by momtothree
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To: ConservativeDude

[It would be tragic, but hardly surprising, if we found out clinically that even skin cancer was boosted by low vitamin D levels....]

My brother just survived melanoma. We think vitamin D deficiency was part of it.


8 posted on 10/03/2011 12:01:13 PM PDT by DaxtonBrown (http://www.futurnamics.com/reid.php)
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To: decimon

Seems like we have a Catch-22 here.

Get some sun = prevent cancer.

Get some sun = get cancer.


9 posted on 10/03/2011 12:01:32 PM PDT by fellowgeek (To geek or not to geek.)
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To: RnMomof7

“Because of the NEW standards almost EVERYONE is deficient in Vit D”

Reams of new research is showing that the old standards were grossly inadequate for optimal health. There are no big bucks in this for the pharmaceutical industry (unless they can get high doses of Vitamin D outlawed...and they’re working on that).


10 posted on 10/03/2011 12:04:57 PM PDT by Magic Fingers
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To: DaxtonBrown

my goodness...I am sorry to hear that, but thrilled that he survived!


11 posted on 10/03/2011 12:05:20 PM PDT by ConservativeDude
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To: ConservativeDude
It would be tragic, but hardly surprising, if we found out clinically that even skin cancer was boosted by low vitamin D levels....

Or that changes in the body's metabolism and cell-signaling mechanisms induced by cancer result in low vitamin D levels--one such thing could be that vitamin D in the body is synthesized from cholesterol and a rapid proliferation of cancer cells requires cholesterol, thus depleting a substrate for vitamin D synthesis; another could be that since vitamin D is required for various nuclear hormone receptors having to do with cell growth and differentiation, the reduction of vitamin D could come from an increased use of it by rapidly proliferating cancer cells or from an attempt by the body to fight the rapid proliferation by reducing the amounts of vitamin D available for tumor proliferation.

On the other hand, it has been found to interfere with receptor tyrosine kinases, to inhibit cell proliferation, angiogenesis (absolutely required for tumor progression), as well as to facilitate cell differentiation (the loss of which sometimes results in cancer) and apoptosis (a way the cell kills itself when something goes awry).
12 posted on 10/03/2011 12:06:24 PM PDT by aruanan
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To: decimon

Omega 3 isn’t in a persons cells either who have cancer.


13 posted on 10/03/2011 12:06:30 PM PDT by shield ((Rev 2:9 Woe unto those who say they are Judahites and are not, but are of the syna GOG ue of Satan.)
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To: fellowgeek

Get some sun = (maybe) get a highly curable skin cancer
Get some sun = (probably) prevent much more serious cancer


14 posted on 10/03/2011 12:06:38 PM PDT by Magic Fingers
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To: momtothree
. I am still confused over the apples but maybe they will find a link to that eventually?

Apple peels contain a substance that seems to cause lower incidences of some cancers in those who consume apples regularly. There have been studies in the Scandinavian countries. I think it might be the quercetin, but am not positive.

I'll see if I can Google something on those studies.

15 posted on 10/03/2011 12:07:18 PM PDT by Will88
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To: Cherokee Conservative

I’ve never been diagnosed with Vot D deficiency while living in Buffalo, NY for 40 years (Avg day of sunshine is 32 days a year)....I moved to Florida and I’m deficient and have to take supplements.


16 posted on 10/03/2011 12:08:36 PM PDT by Fawn (No TO PERRY!!!!!!!!!)
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To: aruanan

Based in most of the research I’ve seen I lean toward “on the other hand”.


17 posted on 10/03/2011 12:10:07 PM PDT by Magic Fingers
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To: Fawn

I am not being snarky at all, Fawn, but doesn’t Vitamin D levels normally drop as we hit middle age? I know my doctor recommended Vitamin D pills (via vitamins) when I hit 40.


18 posted on 10/03/2011 12:12:27 PM PDT by momtothree
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To: momtothree

Here is a link that mentions benefits of apple peel. It is an ad, but I’ve seen studies before and there have been several.

http://loveraw.blogspot.com/2011/03/start-using-apples-in-your-breakfast_27.html


19 posted on 10/03/2011 12:13:20 PM PDT by Will88
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To: Will88

That would absolutely explain it (at least in my eyes). Perhaps the body “knows” it has cancer and creates those cravings? Either way, I found it odd at the time but things like that never leave you.


20 posted on 10/03/2011 12:14:45 PM PDT by momtothree
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To: Will88

It makes total sense to me. Thank you, Will88! (one of the cancers listed in the article is the type he died from)


21 posted on 10/03/2011 12:17:10 PM PDT by momtothree
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To: theKid51

ping


22 posted on 10/03/2011 12:20:50 PM PDT by bmwcyle (Obama is a Communist, a Muslim, and an illegal alien)
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To: aruanan

My husband was just diagnosed with prostate cancer last week. He’s been a vegan for the past few years, and his cholesterol is very low. I think that his vitamin D levels may be low. He doesn’t get outside enough, and we live in N. California.

My daughter is low on vitamin D due to anti-seizure medication. It’s been difficult to get her levels up to normal. Low vitamin D causes all sorts of problems.


23 posted on 10/03/2011 12:21:57 PM PDT by luckystarmom
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To: aruanan

My husband was just diagnosed with prostate cancer last week. He’s been a vegan for the past few years, and his cholesterol is very low. I think that his vitamin D levels may be low. He doesn’t get outside enough, and we live in N. California.

My daughter is low on vitamin D due to anti-seizure medication. It’s been difficult to get her levels up to normal. Low vitamin D causes all sorts of problems.


24 posted on 10/03/2011 12:22:09 PM PDT by luckystarmom
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To: momtothree
Perhaps the body “knows” it has cancer and creates those cravings?

I've long believed that when the body craves certain foods or substances, that the food or substance will be very beneficial or very detrimental.

I'd bet, except for the proverbial sweet tooth, that most cravings for specific foods are for something the body needs.

25 posted on 10/03/2011 12:24:15 PM PDT by Will88
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To: ConservativeDude

Melanoma skin cancer IS higher among the sunlight/ vitamin D deficient.


26 posted on 10/03/2011 12:24:46 PM PDT by Williams (Honey Badger Don't Care)
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To: ConservativeDude

Melanoma skin cancer IS higher among the sunlight/ vitamin D deficient.


27 posted on 10/03/2011 12:26:34 PM PDT by Williams (Honey Badger Don't Care)
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To: RnMomof7
Because of the NEW standards almost EVERYONE is deficient in Vit D

Actually, this is due to the growing awareness of the detrimental impact of Vit D insufficiency compounded by the scare mongering of the dermatologists and the varying bioavailability of VitD supplements.

Stop depending on eating processed Vit D - cancer patients should be tanned/mildly sunburned all the time.

/end rant

28 posted on 10/03/2011 12:27:25 PM PDT by corkoman
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To: decimon
The area in which this study was conducted (Northeast PA) is already an area where many people don't have enough vitamin D, especially older individuals. Did the researchers take this into account? Being sick would also tend to lead to more vitamin deficiency.

Maybe they are on to something, but I'd like to see all the controls.

29 posted on 10/03/2011 12:28:55 PM PDT by Rokurota
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To: ConservativeDude

Melanoma skin cancer IS higher among the sunlight/ vitamin D deficient.


30 posted on 10/03/2011 12:31:26 PM PDT by Williams (Honey Badger Don't Care)
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31 posted on 10/03/2011 12:38:45 PM PDT by TheOldLady (FReepmail me to get ON or OFF the ZOT LIGHTNING ping list)
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To: Fawn

Likely your new doctors have a higher standard for the vitamin D level you require?


32 posted on 10/03/2011 12:55:05 PM PDT by 9YearLurker
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To: pandoraou812
Vit D ping.

Gotta have it! ;-)

33 posted on 10/03/2011 1:24:38 PM PDT by TigersEye (Life is about choices. Your choices. Make good ones.)
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To: DaxtonBrown

Do you think you could explain in more detail your experience. I ask because my dad was diagnosed with a rare form of melanoma called desmal plastic, eight years ago. He actually went into remission with an oral chemo called Timadar. Three weeks after that he developed another cancer call Merkel Cell which is another deadly and extremely aggressive and fast growning skin cancer. Regular IV chemo did nothing. He will be starting a clinicl trial that might hold it at bay but there are no promises since this is a rare form of cancer.

We have been praying like crazy for a miracle. If this trial doesn’t work, I hope that there may be another one for him to try.

He is wary about the vitamin regimine because he only wants to take exactly what his doctors say are okay for hin to take.


34 posted on 10/03/2011 2:08:09 PM PDT by diamond6 (Check out: http://www.biblechristiansociety.com/home.php and learn about the faith.)
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To: decimon

That’s probably why Maine has such a high cancer rate. Maine is “a place where the sun don’t shine”.


35 posted on 10/03/2011 2:52:26 PM PDT by ROCKLOBSTER ( Celebrate Republicans Freed the Slaves Month.)
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To: corkoman
Stop depending on eating processed Vit D - cancer patients should be tanned/mildly sunburned all the time.

Yes, they call that "Radiation therapy"....with the nefarious Liner Accelerator.

36 posted on 10/03/2011 2:59:56 PM PDT by ROCKLOBSTER ( Celebrate Republicans Freed the Slaves Month.)
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To: Magic Fingers
Based in most of the research I’ve seen I lean toward “on the other hand”.

Probably so. Vitamin D has been found relatively recently to be involved in a huge number of processes aside from preventing Vitamin D deficiency disease.
37 posted on 10/03/2011 3:16:06 PM PDT by aruanan
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To: decimon

I have been taking Vitamin D3 for about a week now after reading another FR thread .. The power Of (Vitamin) D

http://www.freerepublic.com/focus/news/2783585/posts?q=1&;page=51

I am taking 1000iu twice a day (2000iu daily)

Thoughts on how much someone should be taking??


38 posted on 10/03/2011 3:45:16 PM PDT by free_life (If you ask Jesus to forgive you and to save you, He will.)
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To: free_life
I have been taking Vitamin D3 for about a week now after reading another FR thread .. The power Of (Vitamin) D

That was a good post. The article was a good synopsis of what's going on with vitamin D.

I am taking 1000iu twice a day (2000iu daily)

Thoughts on how much someone should be taking??

I can't make recommendations.

If I'm up to date then Dr. Holick is a 2,000IU a day man and Dr. Cannell a 5,000IU a day man. There are too many variables for any blanket recommendation so everyone recommends a blood test to determine need.

39 posted on 10/03/2011 3:54:23 PM PDT by decimon
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To: decimon; free_life

I’ve been in the Cannell (and Rheinhold Vieth) camp of 5,000-10,000 i.u./day for a couple of years (when I don’t get 30 minutes of sun - hoping to forestall prostate cancer recurrence). Latest (25-OH D) blood test = 75 ng/mL. Some (not many, mainly in Europe) MD’s/ND’s recommend an upper limit of 200 ng/mL while most are saying 50/100 is best for optimal health.


40 posted on 10/03/2011 4:19:37 PM PDT by Magic Fingers
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To: diamond6

“He is wary about the vitamin regimine because he only wants to take exactly what his doctors say are okay for hin to take.”

Understandable but also potentially dangerous, depending on how open his doc is to complementary therapies.


41 posted on 10/03/2011 4:23:08 PM PDT by Magic Fingers
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To: Will88

I believe you are absolutely correct. Even in pregnancy, women may develop strong cravings for food items (many of which they don’t even like). I remember eating peanut butter by the spoonful (truth be know, I am not that fond of PB in the regular form). Not to get into anything too personal or “too much information” but many women will crave red meat during certain times as well (I am assuming the iron). I personally know one cousin who eats as little meat as possible but will indulge her cravings for a big, medium rare steak... about once a month. Sometimes the body definitely knows best! (I hope I didn’t completely embarrass you!)


42 posted on 10/03/2011 5:09:25 PM PDT by momtothree
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To: momtothree

No embarrassment, and there is always the example of wild animals and cattle seeking out salt and mineral licks to obtain the sodium and other minerals they need.


43 posted on 10/03/2011 6:44:36 PM PDT by Will88
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To: Fawn

That’s just weird. I spent the summer riding my Harley all over Washington, Idaho, and Montana and look like the Indian I am, and that took care of the vitamin D deficiency. It must take a lot of sun. It’s a conspiracy! They tell us to stay out of the sun so we’ll all get cancer and die. /sarc


44 posted on 10/04/2011 3:28:44 PM PDT by Cherokee Conservative (If a tree falls over in the woods, and then snaps back upright as a joke, do the squirrels laugh?)
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To: Magic Fingers

Exactly.

In the 20’s and 30’s it was noted that people who had skin cancer rarely (quite a significant difference) suffered from one of the other deeper, much more critical forms, like lung cancer and colon cancer, etc.

read it years ago, don’t have a reference ping... but I didn’t doubt it then and I don’t doubt it now.


45 posted on 10/04/2011 3:40:26 PM PDT by djf (Soon you will need a prescription for EVERY SINGLE VITAMIN.)
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