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Gila Monster Saliva Reduces Food Cravings
LiveScience ^ | 15 May 2012

Posted on 05/17/2012 10:56:25 PM PDT by nickcarraway

A naturally occurring compound in the saliva of the Gila monster lizard helps reduce food cravings, by downgrading how rewarding a sweet treat is to rats, new research suggests.

After ingesting the compound, called exendin-4, the rats lost their cravings for both food and chocolate, the researchers said. Their study will be published in the April 4th issue of the Journal of Neuroscience.

"The implications of the findings are significant," study researcher Suzanne Dickson, of the University of Gothenburg, said in a statement. "Most dieting fails because we are obsessed with the desire to eat, especially tempting foods like sweets. As exendin-4 suppresses the cravings for food, it can help obese people to take control of their weight."

In the study they found that the compound makes eating less rewarding in the brain, a reaction that can get out of control in obese people, who keep eating in search of more rewarding activity in the brain and often become addicted to eating.

"This is both unknown and quite unexpected effect," study researcher Karolina Skibicka, also of the University of Gothenburg, said in a statement. "Our decision to eat is linked to the same mechanisms in the brain which control addictive behaviors. We have shown that exendin-4 affects the reward and motivation regions of the brain."

Research on exendin-4 also gives hope for new ways to treat eating disorders, for example, compulsive overeating. They also think that exendin-4 may be used to reduce alcohol or drug cravings, Skibicka said: "It is the same brain regions which are involved in food cravings and alcohol cravings, so it would be very interesting to test whether exendin-4 also reduces the cravings for alcohol."

A synthetic version of exendin-4is currently available (it's called Exenatide), and is used by type2diabetics to help control blood sugar levels.

(Excerpt) Read more at livescience.com ...


TOPICS: Food; Health/Medicine; Pets/Animals
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1 posted on 05/17/2012 10:56:31 PM PDT by nickcarraway
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To: nickcarraway
Gila Monster Saliva Reduces Food Cravings

Then how the hell does it ever eat???!?

I mean, DUH.....

2 posted on 05/17/2012 11:02:06 PM PDT by Lazamataz (The so-called 'mainstream' media has gone from "biased" straight to "utterly surreal".)
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To: Lazamataz
Easy, immune to it's own juices, er, spit.

Suffering succotash!. :-)

3 posted on 05/17/2012 11:04:03 PM PDT by going hot (Happiness is a momma deuce)
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To: nickcarraway

“Gila Monster Saliva Reduces Food Cravings”

Now who doesn’t know that! I mean, really.


4 posted on 05/17/2012 11:06:50 PM PDT by ETL (ALL (most?) of the Obama-commie connections at my FR Home page: http://www.freerepublic.com/~etl/)
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To: nickcarraway; Tax-chick; Salamander

Thxs, for the thread.. is there a reptile ping list?


5 posted on 05/17/2012 11:10:35 PM PDT by skinkinthegrass (WA. DC E$tabli$hment; DNC/RNC/Unionists...Brazilian saying: "$@me Old $hit; different flie$". :^)
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To: nickcarraway

".....having one in your bedroom would cut down on the birth rate too"

6 posted on 05/17/2012 11:11:07 PM PDT by Doogle (((USAF.68-73..8th TFW Ubon Thailand..never store a threat you should have eliminated)))
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To: nickcarraway

Gila Monster venom reduces food craving huh? So does rattler venom, cobra venom, arsenic, .45 cal slugs, grizzly bear attacks,,,etc.


7 posted on 05/17/2012 11:12:09 PM PDT by DesertRhino (I was standing with a rifle, waiting for soviet paratroopers, but communists just ran for office.)
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To: nickcarraway

I’ve got it. When a Gila Monster locks onto your arm and your can’t get its jaws to release, the last thing you’ll be thinking about is food.

Makes sense to me /s


8 posted on 05/17/2012 11:12:45 PM PDT by Hoosier-Daddy ( "It does no good to be a super power if you have to worry what the neighbors think." BuffaloJack)
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To: neverdem

ping.


9 posted on 05/17/2012 11:13:30 PM PDT by skinkinthegrass (WA. DC E$tabli$hment; DNC/RNC/Unionists...Brazilian saying: "$@me Old $hit; different flie$". :^)
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To: nickcarraway

First it was toad-licking....

I can only imagine what this will lead to. :p


10 posted on 05/17/2012 11:14:08 PM PDT by Politicalmom (THIS IS NOT A GOP CHEERLEADING SITE!!!)
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To: Politicalmom
don't do that!...their bite is very painful, extremely so....

11 posted on 05/17/2012 11:21:34 PM PDT by skinkinthegrass (WA. DC E$tabli$hment; DNC/RNC/Unionists...Brazilian saying: "$@me Old $hit; different flie$". :^)
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To: nickcarraway
Poison! It kills the appetite. And causes global warming.

Why do you think Gila monsters all live in the desert?

12 posted on 05/17/2012 11:22:17 PM PDT by TigersEye (Life is about choices. Your choices. Make good ones.)
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To: nickcarraway

It tightens up the stomach. A few years back my doctor got on a kick of trying all the new stuff for diabetes, and he put me on it, a shot before the evening meal. The problem is that I don’t eat much as it is, and it was making me too sick to eat my second meal. It wasn’t worth the $50 bucks a month.


13 posted on 05/17/2012 11:23:55 PM PDT by pallis
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To: nickcarraway

Sounds like something that goes into witches’ brew, while they chant:

Saliva of monster,
eye of Newt,
Give up donuts,
Eat more fruit!


14 posted on 05/17/2012 11:24:04 PM PDT by married21 (As for me and my house, we will serve the Lord.)
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To: nickcarraway

ummmmm......no thanks, I’m good.


15 posted on 05/17/2012 11:26:43 PM PDT by jazzo (Resistance is Futile)
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To: Lazamataz

I knew Helen Thomas and Joyce Behar were good for something.


16 posted on 05/17/2012 11:36:09 PM PDT by MadMax, the Grinning Reaper
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To: nickcarraway

So I wonder what made then want to investigate the saliva of a gila monster?

And who the heck would ever want to test this?


17 posted on 05/17/2012 11:48:13 PM PDT by Aria ( 2008 wasn't an election - it was a coup d'etat.)
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To: nickcarraway

I gotta admit the thought of drinking Gila monster spit doesn’t do much for my appetite...


18 posted on 05/17/2012 11:53:51 PM PDT by CitizenUSA (Why celebrate evil? Evil is easy. Good is the goal worth striving for.)
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To: nickcarraway

Yep, get your own Gila monster and give it a big ole sloppy kiss! No more sppetite.


19 posted on 05/18/2012 12:16:05 AM PDT by count-your-change (You don't have to be brilliant, not being stupid is enough.)
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To: nickcarraway

Having a Gila monster spit on my food, does reduce my appetite.


20 posted on 05/18/2012 1:24:04 AM PDT by DannyTN
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