Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Case study shows patient on ketogenic diet living fully with IDH1-mutant glioblastoma
MedicalXPress / Boston College / Frontiers in Nutrition ^ | June 10, 2021

Posted on 06/10/2021 9:04:17 PM PDT by ConservativeMind

click here to read article


Navigation: use the links below to view more comments.
first previous 1-2021-4041-56 last
To: nagant

Fascinating!


41 posted on 06/11/2021 11:19:11 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 36 | View Replies]

To: Varda

Thank you.


42 posted on 06/11/2021 11:25:46 AM PDT by Czech_Occidentalist
[ Post Reply | Private Reply | To 40 | View Replies]

To: Grey182

**I got a sugar intolerance, sucrose intolerance I think, I just don’t know how I got it.**

I’m in the same boat. I would have to be tested, but I think I have an ALDH-2 mutation and a GAPDH (glyceraldehyde 3-phosphate dehydrogenase) mutation. There are over 20 known ALDH’s. ALDH-2 is the ALDH responsible for catalyzing the alcohol and fructose aldehyde. GAPDH is the ALDH responsible for catalyzing the glycerol aldehyde. The tests for these deficiencies test for metabolic markers so you might have to consume your poison to get an accurate result.


43 posted on 06/11/2021 12:06:37 PM PDT by nagant
[ Post Reply | Private Reply | To 37 | View Replies]

To: Czech_Occidentalist

There’s hope:

https://perfectketo.com/ketosis-kidney/


44 posted on 06/11/2021 12:07:37 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 38 | View Replies]

To: ConservativeMind

**Since dietary fats have been unfairly demonized for the past few decades, some people are worried that keto may affect your internal organs.

Specifically, there’s controversy about the keto-kidney connection.

So is the low carb, high fat lifestyle bad for your kidneys?**

Too much fat has no effect that I know of. Too much protein raises blood urea nitrogen (BUN). That can be hard on kidneys.


45 posted on 06/11/2021 12:36:57 PM PDT by nagant
[ Post Reply | Private Reply | To 44 | View Replies]

To: nagant

But this is additionally helpful, regardless of protein:

Studies have shown that a properly formulated ketogenic diet can help reverse diabetic nephropathy[*].

Keto can improve this condition due to two main reasons:

#1: Glycemic Control

It’s hypothesized that more efficient glycemic control can help combat this diabetic kidney condition.

Ketone bodies like beta-hydroxybutyrate (BHB) help reduce the response to glucose and balance blood sugar, which can improve type II diabetes.

And just two months later, diabetic nephropathy was completely reversed in the mice who were on the ketogenic diet[*].

This shows that the ketogenic diet is highly effective for glycemic control and preventing early death due to kidney disease.

#2: Ketosis Positively Alters Genetic Expression in Your Kidneys

The previous study also found the gene expression of the mice had changed.

The researchers found the genes responsible for nephropathy — nephrin, ZO-1 and podocin — were reversed. This helped restore the mice’s kidneys back to healthy functioning[*].


46 posted on 06/11/2021 1:23:30 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 45 | View Replies]

To: Grey182

**I got a sugar intolerance, sucrose intolerance I think, I just don’t know how I got it.**

I should have mentioned that sucrose is 1/2 glucose and 1/2 fructose. The two sugars separate virtually immediately in the digestive system. Glucose is useable directly by cells. Fructose is the problem, and requires metabolism via ALDH-2.


47 posted on 06/11/2021 1:50:23 PM PDT by nagant
[ Post Reply | Private Reply | To 37 | View Replies]

To: ConservativeMind

Thank you.


48 posted on 06/11/2021 2:13:08 PM PDT by Czech_Occidentalist
[ Post Reply | Private Reply | To 44 | View Replies]

To: Czech_Occidentalist

Make sure you read through to where it talks about “The Ketogenic Diet Can Help Prevent Cardiovascular Disease in People with Chronic Kidney Disease.”

You will find it can actually fully reverse early diabetic nephropathy.


49 posted on 06/11/2021 2:21:14 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 48 | View Replies]

To: ConservativeMind

It is what it is, but I equate exercising as a reaction to food intake to the condition labeled bulimia. Nobody knows what the numbers are; they’re all educated guesses for what I assert are unique, individual needs...the latter being the overarching reason that there are so many wildly differing results on any given ‘diet’ (I am clearly not a fan of the 4-letter word).

I’m an experiment in-process. One thing I refused to engage - admittedly potentially health compromising from at least one perspective - was energetic cardio/resistance exercise coupled to weight loss (tried that as a young adult; “burning the candle at both ends” is not merely cliche’). My own focus is healing and I have a hypothesis about the negative impacts - both health & psychological - of the literal yo-yo so many people experience (including yours truly at one time; been there, done that).

One aspect - outlined in the books - is that there is no “one size fits all” in terms of ‘diet’. It’s fantasy. That and the many components of my own personally-tailored cyclical menu are far too detailed to outline in a comment.

But suffice it to state that I regularly enjoy what are termed ‘bad carbs’ with no consequence. In fact, my nightly snacks currently have me enjoying a rotating mix of rutabega fries, potato fries and a variety of ice cream (one pint/serving).

Next month it may be nightly fresh backed cookies. One of my favorites is an apple/walnut spice cookie with a drizzle of frosting.

With little effort at all, since I began this so-called “french fry & ice cream diet” I’ve lost another 10 lbs but, again, that’s not my focus: The weight loss is merely an effect, not my goal.

In terms of the numbers, I assure you that the components of my breakfast & lunch alone are more than 100g of simple carbs, not including my evening snacks.

I simply cannot embrace/sanction/recommend this ‘diet’ or that ‘diet’ due to the fact that they all generate red flags by my standards, failing to take into account other factors, attempting to function as a sort of ‘bible’ for adherents (no offense). It is no coincidence that ‘keto’ is a multibillion dollar industry.

Regardless, the most interesting aspect of that reference to me is the study of the cleansing effects of foods on the organs and I really need to make the time to study it in depth (I’d never come across it until the other night). I could care less at this time about dietary intake to combat cancer, as my focus is on healing and immune health, imho an ‘anti’-cancer formula.


50 posted on 06/11/2021 4:06:05 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
[ Post Reply | Private Reply | To 32 | View Replies]

To: mewzilla

Carbs are cheap.


And very profitable.


51 posted on 06/11/2021 4:10:23 PM PDT by nesnah (Infringe - act so as to limit or undermine [something]; encroach on)
[ Post Reply | Private Reply | To 15 | View Replies]

To: BrandtMichaels

No problem.

Kudos on the progress, but some free advice:

Success on ‘keto’ is a symptom, imho; I suggest widening your field and reduce the focus, as there are major clues in your comments on which I cannot elaborate.


52 posted on 06/11/2021 4:11:30 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
[ Post Reply | Private Reply | To 33 | View Replies]

To: logi_cal869

I definitely want to hear about your progress. Please keep me in your loop.


53 posted on 06/11/2021 4:16:35 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 50 | View Replies]

To: logi_cal869

Outside of walking and some resistance training, I can say the most impactful exercise I’ve done was sprinting (HIIT). I could do three or four all out sprints, eventually getting to over a minute each before absolute, nearly vomit-inducing, exhaustion. I would not do my next sprint until my heart rate got below 120 beats a minute.

The fat really came down from less than four minutes of exercise, every 2-3 days.


54 posted on 06/11/2021 4:21:19 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 50 | View Replies]

To: ConservativeMind

Low carb diets cure most of the diseases that make Big Pharma rich - that’s why they have been getting the hydroxychloroquine treatment from the medical establishment and media for the last thirty years.


55 posted on 06/12/2021 6:47:25 AM PDT by Mr. Jeeves ([CTRL]-[GALT]-[DELETE])
[ Post Reply | Private Reply | To 1 | View Replies]

To: nagant

“Too much fat has no effect that I know of. Too much protein raises blood urea nitrogen (BUN). That can be hard on kidneys.”

Correct, and the thing is that there are 2 factors to a Keto diet, very low carbs, and high fat. For most people, that’s flipping two of the major nutritional constituents on their heads. Most people going on Keto understand the first, since you’re still allowed to eat delicious food - but the second is tougher, getting used to NOT cutting the fat off a steak, for example, and trying TO eat red meat rather than other meats, which are both low/zero carb and low fat - meaning they’re very protein-heavy (like poultry and fish).

Healthy kidneys will be fine if protein is kept reasonably low when eliminating carbs, but you do have to pay attention to that.


56 posted on 06/12/2021 7:03:18 AM PDT by BobL (I shop at Walmart and eat at McDonald's, I just don't tell anyone, like most here.)
[ Post Reply | Private Reply | To 45 | View Replies]


Navigation: use the links below to view more comments.
first previous 1-2021-4041-56 last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson