When I was in the Navy I went to the range with some of our sailors and a handful of M-11s, the SIG 228 in 9mm. I was surprised how many of the women had troubles pulling the double action trigger.
i guess my other option is to keep a round chambered, so all she has to do is flip the safety off on the AR. The dbl action trigger on the sig won’t work but I bet the glock trigger might. She probably wouldn’t be able to get many shots off but then it wouldnt take many with a .45.