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Machine Evolution
Astrobiology Magazine ^ | 7/21/2008 | James Kling

Posted on 07/22/2008 5:37:49 PM PDT by Soliton

Many scientists believe that life started out as nothing more than strands of proto-genetic material known as RNA. A new device automates studies of RNA evolution and could lend insights into the origin of life on Earth.

“This is testing evolution – real evolution, not a simulation. The molecules are evolving a new function before your eyes,” says Joyce.

(Excerpt) Read more at astrobio.net ...


TOPICS: Science
KEYWORDS: evolution
Now, I suspect some will disagree with this statement.
1 posted on 07/22/2008 5:37:49 PM PDT by Soliton
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To: Soliton

Who built the machine? Or did it assemble its self?


2 posted on 07/22/2008 6:00:03 PM PDT by count-your-change (you don't have to be brilliant, not being stupid is enough.)
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To: Soliton

I wish there were more detail in this article. How plausible would it be in Earth’s history that a given RNA strand would be in a soup containing suitable oligonucleotides and appropriate proteins for self-replication? A related question is under what conditions would such oligonucleotides (and proteins) be created abiotically and in quantity?


3 posted on 07/22/2008 6:05:23 PM PDT by rightwingcrazy
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To: rightwingcrazy

I posted another thread a couple a days ago. They have found RNA enzymes (Ribozymes)that can reproduce. Crick predicted it in 1969.


4 posted on 07/22/2008 6:07:42 PM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: count-your-change
Who built the machine? Or did it assemble its self?

It is simply protons, neutrons and electrons assembled by other protons, neutrons, and electrons that were assembled by biological/ chemical processes that occur naturally.

5 posted on 07/22/2008 6:10:23 PM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: Soliton

Then the results are meaningless happenstance. Thanks.


6 posted on 07/22/2008 6:21:35 PM PDT by count-your-change (you don't have to be brilliant, not being stupid is enough.)
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To: count-your-change
Then the results are meaningless happenstance. Thanks.

Everything is meaningless to those without the knowledge , education, and willingness to understand the meaning.

7 posted on 07/22/2008 6:36:14 PM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: Soliton
It is simply protons, neutrons and electrons assembled by other protons, neutrons, and electrons that were assembled by biological/ chemical processes that occur naturally.

Wrong. The RNA had to be fed nucleotides which were generated for it by people.

Also, unless you believe in cold fusion, protons and neutrons are not assembled into elements under terrestrial conditions using "biological/chemical processes;" the elements necessary for life were probably generated long ago and far away by nuclear processes in stars, which are not considered to be within the realm of "chemistry."

8 posted on 07/22/2008 6:55:18 PM PDT by hellbender
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To: hellbender
Wrong. The RNA had to be fed nucleotides which were generated for it by people.

People are the protons, neutrons and electrons that I was referring to that arose from naturally occuring biological/ chemical processes.

9 posted on 07/22/2008 6:57:48 PM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: Soliton

“early studies began with a pool of random RNA sequences and challenged them to attach an oligonucleotide to themselves. The oligonucleotide bore a signal that recruited proteins, also present in the mixture, which in turn replicated the RNA. This enabled successful RNA sequences to be reproduced, just as occurs in natural selection.”


10 posted on 07/22/2008 7:01:10 PM PDT by allmendream (If "the New Yorker" makes a joke, and liberals don't get it, is it still funny?)
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To: count-your-change; Soliton

Sorry guys, you’re chasing a wild goose. Evolution and creation are not two sides of the same coin.

Evolution — improving a population through selection and mutation — does occur; it is a widely recognized branch of computing these days (see for example http://www.amazon.com/dp/3540401849) as well as biology.

The existence of evolution says nothing about the creation of life.


11 posted on 07/22/2008 7:03:12 PM PDT by FRForever (http://www.constitutionparty.com -- Bob Barr for President!)
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To: count-your-change

Who designed the blueprint for the machines?


12 posted on 07/22/2008 7:08:48 PM PDT by LiteKeeper (Beware the secularization of America; the Islamization of Eurabia)
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To: hellbender
the elements necessary for life were probably generated long ago and far away by nuclear processes in stars, which are not considered to be within the realm of "chemistry."

My point is that life on earth is made up of protons, neutrons and electrons (together an "atom") just like the experimental machine is. I left out the step that some lighter atoms were formed in the big bang, some elements are formed by fusion in single stars, some in successions of stars, and those heavier than iron are formed in super-novae.

These protons, neutrons, and eletrons are arranged by the natural occuring chemival/biological processes.

13 posted on 07/22/2008 7:09:53 PM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: FRForever
The existence of evolution says nothing about the creation of life.

darwinism says nothing about the origins of life, but chemical evolution does

14 posted on 07/22/2008 7:11:40 PM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: Soliton
People are the protons, neutrons and electrons that I was referring to that arose from naturally occuring biological/ chemical processes.

There is absolutely nothing in the linked article which indicates where people came from. You are trying to stretch a very limited experiment in order to support your belief that our existence is a matter of pure chance. You continue to neglect, or seek to distract attention from, these facts: 1) the RNA molecules did not assemble themselves at the beginning of the experiment, and 2) the RNA was fed by highly intelligent beings using very sophisticated apparatus.

And again, protons, neutrons, and electrons do not arise by "biological/chemical processes!"

15 posted on 07/22/2008 7:21:28 PM PDT by hellbender
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To: hellbender
And again, protons, neutrons, and electrons do not arise by "biological/chemical processes!"

Aren't atoms made up of protons, neutrons and electrons. Do not atoms join other atoms based on their outer shell electrons and isn't that the definition of chemistry? Aren't we made of atoms and doesn't our remaining alive depend on chemical processes?

16 posted on 07/22/2008 7:30:45 PM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: Soliton

I’d like to see it, if I can find it.

Still, from what I’ve seen elsewhere, a plausible “bootstrap” scenario is still lacking, where enough of the first self-replicating molecules (let alone their precursors) are generated abiotically and randomly from simpler stuff, in stable conditions where they can then self-replicate for a good long time, sufficiently long to yield versions of greater and greater robustness.

I also haven’t seen a serious analysis addressing the statistical likelihood of those conditions occurring spontaneously somewhere, some time on the early Earth. I have seen some hand waving, but that leaves us deep in the world of conjecture.


17 posted on 07/22/2008 8:12:16 PM PDT by rightwingcrazy
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To: Soliton; hellbender
You guys may be interested in this :
18 posted on 07/22/2008 8:13:30 PM PDT by brityank (The more I learn about the Constitution, the more I realise this Government is UNconstitutional !!)
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To: Soliton
Just the usual problem of in vitro vs. in vivo.

Psychologists and others in the humanities run into something similar all the time.

You can control things in the lab, yes; but away from the lab how many other factors are interfering or overshadowing the subtle effects you have isolated?

Cheers!

19 posted on 07/22/2008 8:30:50 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: hellbender
Hans Bethe *placemarker*.

Cheers!

20 posted on 07/22/2008 8:31:33 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: rightwingcrazy

http://www.sciencedaily.com/releases/2008/07/080717140459.htm

Glimpses Of Earliest Forms Of Life On Earth: Remnant Of Ancient ‘RNA World’ Discovered

“We predicted that there would be an ancient ‘RNA city’ out there in the jungle, and we went out and found it,’’ Breaker said.

Bacterial use of RNA to trigger major changes without the involvement of proteins resolves one of the questions about the origin of life: If proteins are needed to carry out life’s functions and DNA is needed to make proteins, how did DNA arise?

The answer is what Breaker and other researchers call the RNA World. They believe that billions of years ago, single strands of nucleotides that comprise RNA were the first forms of life and carried out some of the complicated cellular functions now done by proteins. The riboswitches are highly conserved in bacteria, illustrating their importance and ancient ancestry, Breaker said


21 posted on 07/22/2008 8:47:49 PM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: grey_whiskers
You can control things in the lab, yes; but away from the lab how many other factors are interfering or overshadowing the subtle effects you have isolated?

How is this different than experimental research in any other branch of science?

22 posted on 07/22/2008 8:49:43 PM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: Soliton

Thanx.


23 posted on 07/22/2008 9:03:04 PM PDT by rightwingcrazy
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To: Soliton
The problem is that it combines science with certain features of sociology, psychology, and history.

That is, while you may be able to remove the confusing causes in the lab, once you are in the wild, it becomes much more of a challenge to list all of them, let alone assign them relative or absolute importance.

And as far as history -- we can't re-create the battle of Waterloo; and we can't *guarantee* that the mole fractions of the substrates used in these experiments is a good approximation to those present under primodial conditions; let alone the other conditions.

(Was it you who posted the fascinating article about the kinetics of self-organization of RNA at low T??)

All it means is, the conclusions are not as easily extended as they might be in some other physics/engineering studies.

Or, as Murphy's Laws state, "under the most rigorously controlled conditions of temperature, pressure, and humidity, the organism will do as it damn well pleases."

Cheers!

24 posted on 07/22/2008 9:04:29 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: Soliton
Yes, chemistry covers reactions between atoms based on events in their outer electron shells. It does not cover nuclear reactions involving the strong & weak nuclear forces. You could put loose individual protons, neutrons, and electrons together and never get any organic compounds, unless those protons and neutrons had been forged into the right elements under extreme conditions of temperature and pressure--conditions under which chemistry is impossible. Furthermore, as many physicists and cosmologists now recognize, very minor changes in the initial conditions of the Big Bang would have made eventual formation of even simple building blocks like protons, neutrons, & electrons completely impossible.

And again, the experiment does not demonstrate that nucleic acids can form without assistance from intelligent living beings. (It doesn't prove they can't, either.)

25 posted on 07/23/2008 5:02:37 AM PDT by hellbender
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To: hellbender

Did you miss my reply that stated how elements were formed in stars?


26 posted on 07/23/2008 6:22:57 AM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: Soliton
I saw it, but then you continue to state that neutrons, protons, and electrons got together by sheer chance and formed nucleic acids. You ignore the element stage, and conveniently ignore the fact that the whole experiment was impossible without intervention of highly intelligent beings.

It's obvious you are an ideological zealot who wants to see evolution everywhere, even where there is no evidence. That's exactly like the people who keep harping on Global Warming.

27 posted on 07/23/2008 9:47:12 AM PDT by hellbender
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To: FRForever

” The existence of evolution says nothing about the creation of life.” Say what?
That assumes evolution as fact. Evolutionary theory deals with change over time so unless one is willing to say life had no beginning point, evolution must deal with the creation of life. And if something had a beginning point it was at one point in time not alive before it was alive.
The argument is over the causative agent not whether there was one.


28 posted on 07/23/2008 10:08:35 AM PDT by count-your-change (you don't have to be brilliant, not being stupid is enough.)
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To: hellbender
I saw it, but then you continue to state that neutrons, protons, and electrons got together by sheer chance and formed nucleic acids. You ignore the element stage

No I didn't, I just wasn't explicit. I thought I corrected that. All experiments require an experimenter. This fact does not invalidate all experimental results.

What barrier do you see in chemistry that would prevent pyrimidine and purine from naturally producing RNA over say a billion years?

29 posted on 07/23/2008 10:12:45 AM PDT by Soliton (Investigate, study, learn, then express an opinion)
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To: LiteKeeper
The blueprint maker. Of course one can believe all computers from the simplest calculator to largest largest super computer are random events instead of the result of purposeful design.
30 posted on 07/23/2008 10:15:37 AM PDT by count-your-change (you don't have to be brilliant, not being stupid is enough.)
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To: Soliton
I saw it, but then you continue to state that neutrons, protons, and electrons got together by sheer chance and formed nucleic acids. You ignore the element stage

No I didn't, I just wasn't explicit. I thought I corrected that. All experiments require an experimenter. This fact does not invalidate all experimental results.

What barrier do you see in chemistry that would prevent pyrimidine and purine from naturally producing RNA over say a billion years?

You "corrected it," then went right back to stating that a bunch of elementary subatomic particles sat around and spontaneously turned into nucleic acids and even human beings! You're using tactics reminiscent of Barack Obama. Your whole approach is to convince people of a radically materialistic, reductionist worldview regarding everything in life, including human beings.

The idea that there ever was or can be an "RNA world," capable of developing spontaneously into complex life, is pure speculation at this point, not hard science. The article you cite is junk science, like the one on mustard plants "evolving" in few years. Darwin himself would be horrified by that one. He sat on his ideas for decades, rather than shooting off his mouth in order to get grants and glory.

31 posted on 07/23/2008 1:27:01 PM PDT by hellbender
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To: hellbender

“The article you cite is junk science.”

Ribozymes and Riboswitches have been found as predicted by the RNA world hypothesis. That is not “junk science”.

http://www.sciencedaily.com/releases/2008/07/080717140459.htm


32 posted on 07/23/2008 1:32:32 PM PDT by Soliton (Investigate, study, learn, then express an opinion)
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