Skip to comments.Sunlight can influence the breakdown of medicines in the body (vitamin D?)
Posted on 03/09/2011 10:44:44 AM PST by decimon
[PRESS RELEASE, 9 March 2011] A study from Karolinska Institutet has shown that the body's ability to break down medicines may be closely related to exposure to sunlight, and thus may vary with the seasons. The findings offer a completely new model to explain individual differences in the effects of drugs, and how the surroundings can influence the body's ability to deal with toxins.
The study will be published in the scientific journal Drug Metabolism & Disposition and is based on nearly 70,000 analyses from patients who have undergone regular monitoring of the levels of drugs in their blood. The drugs taken by these patients are used to suppress the immune system in association with organ transplants. Samples taken during the winter months were compared with those taken late in the summer.
A more detailed analysis showed that the concentrations of drugs such as tacrolimus and sirolimus, which are used to prevent rejection following transplantation, vary throughout the year in a manner that closely reflects changes in the level of vitamin D in the body. The ability of the body to form vitamin D depends on sunlight, and the highest levels in the patients taking part in the study were reached during that part of the year when the levels of the drugs were lowest.
(Excerpt) Read more at ki.se ...
Vitamin D deficiency certainly would explain a lot.
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