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Vitamin D improves exercise outcomes in patients with COPD
American Thoracic Society ^ | May 15, 2011 | Unknown

Posted on 05/15/2011 5:41:10 PM PDT by decimon

ATS 2011, DENVER – Vitamin D supplements may help patients with chronic obstructive pulmonary disease (COPD) get more from their pulmonary rehabilitation programs, according to a study conducted by researchers from Belgium.

The study results will be presented at the ATS 2011 International Conference in Denver.

"Our study shows that high doses of vitamin D supplementation on top of a standard rehabilitation program improve the outcome in terms of exercise capacity and respiratory muscle strength," said Miek Hornikx, physiotherapist and doctoral student in the department of pneumology at the Katholieke Universiteit Leuven in Leuven, Belgium.

Vitamin D deficiency is common among patients with COPD, and is often associated with lack of exposure to sunlight and diet. COPD patients also often have limited physical activity as a result of breathing difficulties associated with the disease, which also may result in less exposure to sunlight, Ms. Hornikx explained.

"COPD can be considered as a respiratory disease with important non-respiratory consequences, such as osteoporosis, cardiovascular disease and muscle weakness," she said. "These consequences eventually will be negatively influenced by physical inactivity which, along with exercise intolerance, is a common feature among patients with COPD and is proven to be related to mortality.

"Low levels of vitamin D in the blood have been related with muscle weakness, a major target for respiratory rehabilitation and increased risk of falls," she added "Since vitamin D is often depleted in patients with COPD, we wanted to see if vitamin D supplementation would have a beneficial effect on rehabilitation among these patients, perhaps by increasing muscle strength."

The researchers enrolled 50 COPD patients with a history of exacerbations who had been referred for rehabilitation and randomly assigned them to receive either a monthly dose of vitamin D or placebo. Patients in the vitamin D group were given 100,000 IUs (international units) of vitamin D in their monthly dose; the U.S. recommended daily allowance of vitamin D is 600 IUs daily for adults up to age 70 and 800 IUs daily for adults over age 70.

All patients participated in a pulmonary rehabilitation program for three months. At the beginning of the study and again at the completion of the rehabilitation program, peripheral and respiratory muscle strength, exercise capacity and vitamin D levels were measured. Patients were also asked to complete a quality of life survey both before and after rehabilitation.

At the end of the study, researchers found that patients treated with vitamin D had a significant improvement in exercise capacity and respiratory muscle strength compared to those in the placebo group.

"These results support the idea that correcting vitamin D deficiency by adding vitamin D supplements to training programs allows COPD patients to achieve better results from rehabilitation, including improvements in muscle strength and exercise capacity," Ms. Hornikx said.

Interestingly, despite significant improvements in exercise capacity in patients treated with vitamin D, those patients did not report a significant increase in health-related quality of life.

"This could be due to the fact that we had a relatively small number of patients included in this study, as well as to the relatively brief duration of the study," Ms. Hornikx said. Future studies should focus on the specific mechanisms by which vitamin D affects patients with COPD, she added.

###

"Vitamin D Supplementation During Rehabilitation In Patients With Chronic Obstructive Pulmonary Disease: An Intervention Study" (Session B17, Monday, May 16, 8:15-10:45 a.m., Room 201-203 (Street Level), Colorado Convention Center; Abstract 17477)

* Please note that numbers in this release may differ slightly from those in the abstract. Many of these investigations are ongoing; the release represents the most up-to-date data available at press time.


TOPICS: Health/Medicine
KEYWORDS: vitamind

1 posted on 05/15/2011 5:41:12 PM PDT by decimon
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To: neverdem; DvdMom; grey_whiskers; Ladysmith; Roos_Girl; Silentgypsy; conservative cat; ...

Ping


2 posted on 05/15/2011 5:41:45 PM PDT by decimon
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To: decimon
Patients in the vitamin D group were given 100,000 IUs (international units) of vitamin D in their monthly dose.

I'm not sure what this means. Are they saying that the patients went in once a month and took 100,000 IUs all at once, or that they spread it out over the course of a month, and therefore took about 3,300 IUs a day? The article isn't really clear.

3 posted on 05/15/2011 5:52:00 PM PDT by Cicero
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To: Cicero
I'm not sure what this means. Are they saying that the patients went in once a month and took 100,000 IUs all at once, or that they spread it out over the course of a month, and therefore took about 3,300 IUs a day? The article isn't really clear.

I don't know but that was taken directly from the American Thoracic Society release. The PDF is here.

4 posted on 05/15/2011 6:04:50 PM PDT by decimon
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To: decimon

Interesting..thanks for posting it.. I have COPD and I have VERY low Vit D which I pretty much ignored.. I guess its time to mega dose and see if it helps at the gym


5 posted on 05/15/2011 6:08:42 PM PDT by RnMomof7
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To: RnMomof7
I guess its time to mega dose and see if it helps at the gym

Well, don't over mega. ;-)

May I ask how much daily you're thinking of?

6 posted on 05/15/2011 6:10:56 PM PDT by decimon
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To: RnMomof7

Mom, not just for this, but for any number of other things according to the MDs in these parts, is to put on shorts and a tank top and go out in the sun. The trick is that soap seems to wash the hormone off the skin before it’s absorbed, so it is recommended to only wash the areas where the glands are close to the surface to let the vit D soak in. Any number of people I know here are under orders to raise their levels and with some supplementation, this is the recommended method.


7 posted on 05/15/2011 6:13:15 PM PDT by Desdemona ( If trusting the men in the clergy was a requirement for Faith, there would be no one in the pews.)
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To: RnMomof7
Here is an online resource for the amount of time to spend in the sun:

http://nadir.nilu.no/~olaeng/fastrt/VitD-ez_quartMED.html

8 posted on 05/15/2011 6:16:59 PM PDT by Desdemona ( If trusting the men in the clergy was a requirement for Faith, there would be no one in the pews.)
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To: decimon

I was wondering the same thing. It would seem to me that a 100,000 IU of vitamin D would be like eating sticks of chalk if it was in one dose.


9 posted on 05/15/2011 6:20:04 PM PDT by almost done by half
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To: decimon

Doctor recommended 5,000 units ..I was thinking maybe double that


10 posted on 05/15/2011 6:22:36 PM PDT by RnMomof7
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To: Desdemona

I actually spend time in the sun when I see it in Buffalo ..I garden and walk ... maybe I need more.. You know its funny, there are always unintended consequences. They tell people to wear sun block and suddenly there is an epidemic of low vit D ..DUH...


11 posted on 05/15/2011 6:25:41 PM PDT by RnMomof7
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To: RnMomof7

Exactly. Since I’ve eliminated grains, legumes and the vast majority of sugar from my diet, I don’t really use sunblock any more. I don’t burn like I used to. But, I’m still careful about being in the sun having an Irish complexion.


12 posted on 05/15/2011 6:28:16 PM PDT by Desdemona ( If trusting the men in the clergy was a requirement for Faith, there would be no one in the pews.)
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To: RnMomof7

5,000 a day would be 150,000 IU a month.


13 posted on 05/15/2011 6:29:58 PM PDT by almost done by half
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To: RnMomof7

I was just reading a book on Vit D, I believe the author recommended supplementing at 1,000- 2,000 IU daily. There was a chart showing a level at which the Vit D has some toxicity. It’s a high level, but please ask your doctor before doubling a recommended 5,000 IU.


14 posted on 05/15/2011 6:30:50 PM PDT by Williams (It's the policies, stupid.)
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To: RnMomof7

Because I live in a state where it rains a great deal of the time - Washington - sunshine is scarce.

I take 4000 IU of D3 a day, and have been doing so for years. So far no harmful side effects.


15 posted on 05/15/2011 6:37:59 PM PDT by SatinDoll (NOT FOREIGN NATIONALS AS OUR PRESIDENT)
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To: RnMomof7
Doctor recommended 5,000 units ..I was thinking maybe double that

Depending on who you read, 10,000IU daily may be too high if taken for very long. Blood tests are probably the only way to know for sure. At any rate, good luck with it.

16 posted on 05/15/2011 6:38:59 PM PDT by decimon
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To: RnMomof7
You have to be careful using vitamin D. Its a fat soluble vitamin and the body stores it. Also stores A D E & K. The other vitamins the body excretes after it uses all it can. You can in fact OD on the fat soluble vitamins if not careful....Vit C for instance is excreted in urine and you have too much, your urine will turn very yellow. It gets rid of what it cannot use....not so with A D E K. If I were to take up using vit. D OTC I'd check with the doctor for the proper dose..
17 posted on 05/15/2011 6:39:01 PM PDT by goat granny
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To: decimon

This is about the 6th vitamin D article I’ve seen in the last couple of months on FR. I’m starting to realize it’s a very critical nutrient.


18 posted on 05/15/2011 7:00:09 PM PDT by Free Vulcan (Vote Republican! You can vote Democrat when you're dead.)
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To: Free Vulcan
This is about the 6th vitamin D article I’ve seen in the last couple of months on FR.

It's been a common topic for years.

19 posted on 05/15/2011 7:05:03 PM PDT by decimon
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To: decimon

True, but all the new research is connecting it with cancer, diabetes, cardiovascular, energy and a whole lot of other things. It’s mind boggling that there could be such a simple answer to a great host of problems.


20 posted on 05/15/2011 7:14:34 PM PDT by Free Vulcan (Vote Republican! You can vote Democrat when you're dead.)
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To: decimon
It's amazing how vitamin D has become so important ever since the pharmaceutical companies created their expensive prescription version of the nutrient.

Now all they need are a few “scientific studies” suggesting that D will save the day with this disease or that condition...doctors will gladly hand out the scripts and we (the tax payer) will subsidize (through medicare and medicaid) prescription only D, when people could be buying it for themselves at a fraction of the cost, from their health store.

Very cynical this whole;e prescription only versions of fish oil and D. Just a clever way to make BigPharma richer.

21 posted on 05/15/2011 7:29:43 PM PDT by Awgie (truth is always stranger than fiction)
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To: decimon

Ping for a healthier life!

22 posted on 05/15/2011 8:38:19 PM PDT by Brandonmark (News Coverage)
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To: Mama_Bear

You might want to check this out.


23 posted on 05/15/2011 8:52:07 PM PDT by WVNan
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To: Awgie

What is the prescription form? I usually only read recommendations for the very cheap D3.


24 posted on 05/16/2011 12:49:04 AM PDT by 9YearLurker
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To: Awgie

Most insurance will not cover OTC drugs ( except medicaid perhaps)

My insurance refused


25 posted on 05/16/2011 4:11:02 AM PDT by RnMomof7
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To: WVNan
Thanks, sweet friend. I will check it out. Am also going in for a routine checkup tomorrow and will ask my MD about it too.

I joined a gym last month and am attending some of the exercise classes and working out on the cardio equipment. I am actually pleasantly surprised that I can put in a good half hour on a recumbent cross trainer and then ride a bike for 2 miles (albeit set on zero incline). I would never have believed I could do that with my breathing problems.

26 posted on 05/16/2011 10:14:43 AM PDT by Mama_Bear ("Sorry looks back, worry looks around, faith looks up.")
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To: Mama_Bear

Good for you girl! I’ve been taking vit.D3 for about a year and it has made a big difference in my resistance to colds, etc. Hang in there with the exercise. Wish I had the time. I’m keeping Avery now. Supposed to be 4 days a week, but guess who decided he needs to work on Mondays to catch up? My only day off. I’m getting further and further behind. I will get a break through the summer. Maybe then I will catch up.
Love you and miss you.
Nan


27 posted on 05/16/2011 11:00:52 AM PDT by WVNan
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To: Mama_Bear

Guess who forgot she was responding online instead of private mail? LOL


28 posted on 05/16/2011 11:02:23 AM PDT by WVNan
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To: WVNan

LOL! I’ve done that too! Take it easy as you can. You are an inspiration to me. :-)


29 posted on 05/16/2011 12:21:35 PM PDT by Mama_Bear ("Sorry looks back, worry looks around, faith looks up.")
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