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Researchers find herbal medicine treatment reduces inflammation in allergen-induced asthma
Boston University ^ | June 30, 2011 | Unknown

Posted on 06/30/2011 6:51:43 PM PDT by decimon

(Boston) - Researchers from Boston University School of Medicine (BUSM) using a traditional Korean medicine, SO-CHEONG-RYONG-TANG (SCRT) that has long been used for the treatment of allergic diseases in Asia, found that SCRT treatment alleviates asthma-like pulmonary inflammation via suppression of specific chemokines or proteins. These findings appear online in the Annals of Allergy, Asthma & Immunology.

Asthma is a unique form of chronic respiratory disease characterized by reversible airway obstruction and pulmonary inflammation. It represents one of the most common chronic inflammatory diseases affecting an estimated 300 million people worldwide with an expected increase to 400 million by 2025. The sharply rising prevalence and incidence of asthma causes global concern both in the developed as well as in developing countries.

“In order to elucidate the mechanism of how SCRT modulates the allergic response, we evaluated the immunomodulatory effects of SCRT in a murine model of asthma induced by a house dust extract containing cockroach allergens and endotoxin,” explained Jiyoun Kim, PhD, a research assistant professor of pathology and laboratory medicine at BUSM. “In this study multiple aspects of pulmonary inflammation were examined including the production of inflammatory mediators and the pulmonary recruitment of inflammatory cells,” he added.

The researchers found SCRT treatment significantly reduced airway hyper-reactivity as measured by both whole body plethysmography and direct measurement of airway resistance. The researchers report that the immune response of pulmonary inflammation was significantly inhibited by SCRT treatment as demonstrated by reduced plasma IgE antibody levels and improved lung histology. SCRT significantly reduced the number of neutrophils in the bronchoalveolar (BAL) fluid and also significantly reduced the BAL levels of CXC chemokines both expressed as part of the immune response, providing a potential mechanism for the reduced inflammation.

(Excerpt) Read more at bu.edu ...


TOPICS: Health/Medicine
KEYWORDS: asthma; herbalmedicine; scrt

1 posted on 06/30/2011 6:51:46 PM PDT by decimon
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To: neverdem; DvdMom; grey_whiskers; Ladysmith; Roos_Girl; Silentgypsy; conservative cat; ...

Ping


2 posted on 06/30/2011 6:52:36 PM PDT by decimon
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To: decimon

later


3 posted on 06/30/2011 7:34:31 PM PDT by goodnesswins (...both islam and the democrat plantation thrive on poverty)
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To: decimon

reference bump


4 posted on 06/30/2011 8:25:28 PM PDT by NonValueAdded (From her lips to the voters' ears: Debbie Wasserman Schultz: "We own the economy" June 15, 2011)
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To: decimon

Bump for later.


5 posted on 06/30/2011 9:21:49 PM PDT by Borax Queen
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To: decimon

Mice can now breath easier.


6 posted on 07/01/2011 6:25:10 AM PDT by Rudder (The Main Stream Media is Our Enemy---get used to it.)
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To: decimon; Mother Abigail; EBH; vetvetdoug; Smokin' Joe; Global2010; Battle Axe; null and void; ...

Bump and an immunology ping. Thanks decimon, but I had no luck searching that Elsevier journal for SCRT.


7 posted on 07/01/2011 11:42:35 PM PDT by neverdem (Xin loi minh oi)
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To: Rudder

“via suppression of specific chemokines or proteins”

Help, help, I’m being repressed!


8 posted on 07/02/2011 12:31:12 PM PDT by Pining_4_TX ( The state is the great fiction by which everybody seeks to live at the expense of everybody else. ~)
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To: decimon

If I knew what “SO-CHEONG-RYONG-TANG” is, I would have learned something from this.

The best field-expedient treatment for asthma I know of is hot, black coffee.

It works.


9 posted on 07/02/2011 12:43:34 PM PDT by patton (I am sure that I have done dumber things in my life, but at the moment, I am unable to recall them.)
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To: Pining_4_TX
...help, I’m being repressed!

Try this:

"...whole body plethysmography..."

Sounds like a great, big, pneumatic hug.

Neurotics just love hugs.

10 posted on 07/02/2011 1:27:02 PM PDT by Rudder (The Main Stream Media is Our Enemy---get used to it.)
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To: patton

>> “The best field-expedient treatment for asthma I know of is hot, black coffee.” <<

.
Don’t know ‘bout that, but if you live in the eastern half of the US, the best cure for asthma, and any other restriction of the bronchi, grows beside almost every road: Lobelia.

A plant with a pale blue to white blossom, and bladder-like seed pods (hence its slangular name - “Bladderpod). All you need to do is chew up some seeds, which will temporarily cause a scratchy sensation in your throat, and shortly after complete relief of the bronchial tightness.

No side effects either, (except a slight reduction in blood pressure for some) unless you consume pounds of the stuff.


11 posted on 07/02/2011 1:29:25 PM PDT by editor-surveyor (Going 'EGYPT' - 2012!)
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To: editor-surveyor

Huh - never heard of it. Does it grow in VA?


12 posted on 07/02/2011 1:34:11 PM PDT by patton (I am sure that I have done dumber things in my life, but at the moment, I am unable to recall them.)
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To: decimon

Do you smoke it?


13 posted on 07/02/2011 1:37:52 PM PDT by Revolting cat! (Let us prey!)
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To: patton

Yes, it grows wild all over the east.


14 posted on 07/02/2011 1:41:40 PM PDT by editor-surveyor (Going 'EGYPT' - 2012!)
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To: mongrel

Bump


15 posted on 07/02/2011 1:43:59 PM PDT by mongrel
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To: editor-surveyor

Ahhh, I hate research assignments - now I gotta look it up.

The coffee thing works - believe me, I know. I have used it more than once on my kid, when albuterol didn’t work.

Inhale the vapor, and drink the coffee as fast as you can, without burning the heck out of yourself.

Had to apologize to the kid for my genetic contribution...


16 posted on 07/02/2011 1:50:17 PM PDT by patton (I am sure that I have done dumber things in my life, but at the moment, I am unable to recall them.)
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To: Rudder

That line is from Monty Python and the Holy Grail.

However, I might very well be neurotic. ;-)


17 posted on 07/02/2011 7:30:06 PM PDT by Pining_4_TX ( The state is the great fiction by which everybody seeks to live at the expense of everybody else. ~)
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To: Pining_4_TX
That line from the movie escaped me.

I wasn't to referring to you; besides, neuroticism is passe.

18 posted on 07/02/2011 8:21:36 PM PDT by Rudder (The Main Stream Media is Our Enemy---get used to it.)
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To: decimon

I am having a hard time with asthma this year. I;m on Singulair, 2x daily asthma inhaler and a rescue inhaler but I am still having trouble breathing and feeling dizzy when rising or exerting.
This hot humid weather and the poor air quality it is causing are really making it hard on me.


19 posted on 07/02/2011 8:31:10 PM PDT by kalee (The offenses we give, we write in the dust; Those we take, we engrave in marble. J Huett 1658)
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To: kalee

Hie thee to a Korean grocery.

I don’t know if you’d find this stuff at any grocery but if you can find it and it’s not expensive then it could be worth a try.


20 posted on 07/02/2011 8:37:08 PM PDT by decimon
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To: decimon

Not one in my small town, wonder if there is one in Raleigh/Durham? I would try anything at this point.


21 posted on 07/02/2011 8:42:03 PM PDT by kalee (The offenses we give, we write in the dust; Those we take, we engrave in marble. J Huett 1658)
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To: decimon

BTTT


22 posted on 07/03/2011 7:33:05 AM PDT by DollyCali (Don't tell God how big your storm is... tell your storm how BIG your God is!)
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