They’ve taken on islam several times (remember the times square bomber was targeting them) along with scientologists, catholics, atheists, hair club for men members, truthers, barbara streisand, George bush, Obama, Obama supporters, and peruvrian flute bands.
They had South Park ally with Al Queada and Osama to rid South Park of Snookie and the Jerseyites. One of their funniest episodes.
You left Out NAMBLA, not to be confused with the north american Marlon Brando look alikes.
That is correct.. They also teased Buddha by having him snort cocaine. They tease everyone..