Skip to comments.The Diabetes Dilemma for Statin Users
Posted on 03/06/2012 9:26:10 PM PST by nickcarraway
Were overdosing on cholesterol-lowering statins, and the consequence could be a sharp increase in the incidence of Type 2 diabetes.
This past week, the Food and Drug Administration raised questions about the side effects of these drugs and developed new labels for these medications that will now warn of the risk of diabetes and memory loss. The announcement said the risk was small and should not materially affect the use of these medications. The data are somewhat ambiguous for memory loss. But the magnitude of the problem for diabetes becomes much more apparent with careful examination of the data from large clinical trials.
Statins have been available since the 1980s but their risk of inducing diabetes did not surface for nearly 20 years. When all the data available from multiple studies was pooled in 2010 for more than 91,000 patients randomly assigned to be treated with a statin or a sugar pill (placebo), the risk of developing diabetes with any statin was one in every 255 patients treated. But this figure is misleading since it includes weaker statins like Pravachol and Mevacor which were introduced earlier and do not carry any clear-cut risk. It is only with the more potent statins Zocor (now known as simvastatin), Lipitor (atorvastatin) and Crestor (rosuvastatin) particularly at higher doses, that the risk of diabetes shows up. The cause and effect was unequivocal because the multiple large trials of the more potent statins had a consistent excess of diabetes.
For those statins, the higher the dose, the more diabetes, though we dont have enough data yet to say with precision at which dose excess diabetes showed up for each drug. What we do know is that diabetes showed up. The numbers increase to one in 167 for patients taking 20 milligrams Crestor,
(Excerpt) Read more at nytimes.com ...
It makes me test higher in the morning.
Risk of Diabetes in Patients Taking Thiazide Diuretics
You mean your blood glucose?
USE Niacin...the real stuff...NOT the NON-flushing stuff...it has been proven to be nearly as good (or better) as statins, AND, it’s cheaper. Start on a low dose and build up if you flush. The flushing won’t kill you...it’s just a little bothersome in the beginning.
My doc took me off Simvastin and switched me to Crestor 2 yrs ago. My cholesterol and blood sugar levels are where they should be.
I have taken Pravastatin for 14 years.
I can still remember everything from 1964....Mrs Moffat’s cleavage in Music...I will die with that memory indelibly stained
but what the hell did I eat while typing 30 minutes ago?
i’ll have to look at the bowl
...hmmmm...looks like Blue Bell Chocolate fudge-Coconut
a little memory loss so i can still eat ice cream yet remember female anatomy from 50 years ago is a damned fine trade off in my way of reckoning even if I have to study my kids to remember which is which sometimes
No one should ever take statins period. They are killers. The reason they are prescribed is bogus. The cholesterol is harmful argument is bogus. They kill your immune system and hurt your body and mind, permanently.
Why don’t you make your kids wear name tags?
lol...that actually elicited a laff out loud in my home office
i’m gonna crash on that note if I can find the bed..it’s somewhere upstairs
(just listen for wifey’s snoring)
Lipitor definitely contributes to memory loss that mimics dementia. Doctors have prescribed dosages that are much too high and should be cut in half, generally.
Laughing is a good way to call it a night. And lowers cholesterol.
“USE Niacin...the real stuff...NOT the NON-flushing stuff...it has been proven to be nearly as good (or better) as statins, AND, its cheaper. Start on a low dose and build up if you flush. The flushing wont kill you...its just a little bothersome in the beginning.”
i have been taking red rice yeast (2) and 2000mg niacin for the past year. also lost 22 pounds and exercis at least 200 minutes a week. my overall went from 241 to 183 and all my numbers are great. i take my niacin at night as i turn off the light and am usually asleep before the minor (for me) flushing starts.
Doesn’t the flushing ever stop.....I take 1500 a day, and never flush anymore, unless I miss a couple doses.