Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Sugar makes cancer light-up in MRI scanners
Biology News Net ^ | July 7, 2013 | NA

Posted on 07/08/2013 5:59:57 PM PDT by neverdem


UCL scientists have developed a new technique for detecting the uptake of sugar in tumors, using magnetic resonance imaging.

A new technique for detecting cancer by imaging the consumption of sugar with magnetic resonance imaging (MRI) has been unveiled by UCL scientists. The breakthrough could provide a safer and simpler alternative to standard radioactive techniques and enable radiologists to image tumours in greater detail.

The new technique, called 'glucose chemical exchange saturation transfer' (glucoCEST), is based on the fact that tumours consume much more glucose (a type of sugar) than normal, healthy tissues in order to sustain their growth.

The researchers found that sensitising an MRI scanner to glucose uptake caused tumours to appear as bright images on MRI scans of mice.

Lead researcher Dr Simon Walker-Samuel, from the UCL Centre for Advanced Biomedical Imaging (CABI) said: "GlucoCEST uses radio waves to magnetically label glucose in the body. This can then be detected in tumours using conventional MRI techniques. The method uses an injection of normal sugar and could offer a cheap, safe alternative to existing methods for detecting tumours, which require the injection of radioactive material." Professor Mark Lythgoe, Director of CABI and a senior author on the study, said: "We can detect cancer using the same sugar content found in half a standard sized chocolate bar. Our research reveals a useful and cost-effective method for imaging cancers using MRI – a standard imaging technology available in many large hospitals."
Tumors use large quantities of glucose to sustain their growth. By injecting normal, unlabeled sugar, UCL scientists have developed a way to detect its accumulation in tumors using magnetic resonance

He continued: "In the future, patients could potentially be scanned in local hospitals, rather than being referred to specialist medical centres." The study is published in the journal Nature Medicine and trials are now underway to detect glucose in human cancers.

According to UCL's Professor Xavier Golay, another senior author on the study: "Our cross-disciplinary research could allow vulnerable patient groups such as pregnant women and young children to be scanned more regularly, without the risks associated with a dose of radiation." Dr Walker-Samuel added: "We have developed a new state-of-the-art imaging technique to visualise and map the location of tumours that will hopefully enable us to assess the efficacy of novel cancer therapies."

Source : d.weston@ucl.ac.uk


TOPICS: Health/Medicine; Science
KEYWORDS: cancer; glucocest; glucose; imaging; mri; petscan; sugar
In vivo imaging of glucose uptake and metabolism in tumors
1 posted on 07/08/2013 5:59:58 PM PDT by neverdem
[ Post Reply | Private Reply | View Replies]

To: neverdem

and because it is useful and works, obamacare will deny it.


2 posted on 07/08/2013 6:02:39 PM PDT by Secret Agent Man (Gone Galt; Not averse to Going Bronson.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Secret Agent Man

Obamacare will dispense sugar pills but good luck getting that MRI.


3 posted on 07/08/2013 6:09:23 PM PDT by palmer (Obama = Carter + affirmative action)
[ Post Reply | Private Reply | To 2 | View Replies]

To: neverdem

During the course of treating and caring for my elderly Lab with cancer, I tried most everything. As far as diet, it’s commonly believed that a high protein diet devoid of grain, starches and sugars is beneficial. Grains, starch and sugar “feed” a tumor or so the holistic conventional wisdom goes. I wouldn’t know if it’s true, but my dog loved the diet, his coat came back in glossy and he was happy. The cancer wasn’t what killed him.


4 posted on 07/08/2013 6:11:34 PM PDT by RegulatorCountry
[ Post Reply | Private Reply | To 1 | View Replies]

To: neverdem

PET scans are this way.


5 posted on 07/08/2013 6:13:55 PM PDT by arichtaxpayer
[ Post Reply | Private Reply | To 1 | View Replies]

To: neverdem

You gotta wonder why the first words from the oncologists mouth after giving patients the bad news isn’t “stop eating sugar to increase your chances of survival”.


6 posted on 07/08/2013 6:22:47 PM PDT by numberonepal (First they came for Sarah, then they came for Herman.....)
[ Post Reply | Private Reply | To 1 | View Replies]

To: RegulatorCountry

Check out tumeric. It is a spice that has been shown to shrink or prevent tumors. We give it to our dogs- they love it mixed with water and put on their food. One of our dogs has had several mast cell tumors and had to have them surgically removed. None since we put him on tumeric.

And sorry about the loss of your loved one.


7 posted on 07/08/2013 6:23:19 PM PDT by Cowgirl of Justice
[ Post Reply | Private Reply | To 4 | View Replies]

To: neverdem
Thanks - the usual stuff they give to get a better picture cad cause permanent pain when given in a large enough dose to get a great picture. A kind radiologist shared that with me about a loved on getting the test - and we reduced the amount used. The doctor didn't get a perfect picture to look at for a few seconds - but a loved one didn't have to suffer needlessly the last few weeks of life.. Nice to see they're coming up with better solutions.
8 posted on 07/08/2013 6:33:42 PM PDT by GOPJ (In the kingdom of the blind, the one eyed man is a dangerous extremist.. Greenfield)
[ Post Reply | Private Reply | To 1 | View Replies]

To: numberonepal

Exactly.

I also know a smoker who has mysteriously lost a severe amount of weight. If I were him I would want a full cancer screening. You don’t just loose a ton of weight without something using that energy.


9 posted on 07/08/2013 6:41:08 PM PDT by pennyfarmer (Your socialist beat our liberal AGAIN.)
[ Post Reply | Private Reply | To 6 | View Replies]

To: neverdem

Metformin, ask your MD about it...


10 posted on 07/08/2013 6:42:33 PM PDT by virgin (Don't screw with me.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: neverdem

Seems that something that highlights rumors can be turned up to fry them. Next step?


11 posted on 07/08/2013 6:45:07 PM PDT by piytar (The predator-class is furious that their prey are shooting back.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Cowgirl of Justice

What way do you dispense tumeric?
I have bone lesion on my skull. It may have matastisized from the breast cancer.

I had a whole body scan now I’m fixng to have a PET scan on top area and they use the glucose injection. Later an open MRI for lower area.

For PET scan—Protein only day before scan. No exercise, etc. Nothing 6 hrs before scan..
Glucose injection, then set for 1 hr, then scan. Cancelled twice. I’m claustrophobic.


12 posted on 07/08/2013 6:46:22 PM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 7 | View Replies]

To: virgin

Metformim is for Diabetics. How does that relate?


13 posted on 07/08/2013 6:48:01 PM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 10 | View Replies]

To: arichtaxpayer
PET scans are this way.

Yes, my husband had a number of PET scans. They are much more expensive than MRIs. Organs that normally have high sugar content can't be assessed to have cancer by a PET scan. The kidneys, for instance, will light up whether or not there is cancer there due to the usual sugar that is in the kidneys. When we would see the PET scans, organs normally with sugar were always lit up.

14 posted on 07/08/2013 6:48:11 PM PDT by Marcella (Prepping can save your life today. I am a Christian, not a Muslim.)
[ Post Reply | Private Reply | To 5 | View Replies]

To: numberonepal

All energy sources are converted into sugar before your cells burn it. You can’t starve a tumor.

However, processed sugars no doubt cause unnatural sugar spikes. I wouldn’t be surprised if cancer is more likely to begin in a high sugar environment


15 posted on 07/08/2013 6:51:06 PM PDT by varyouga
[ Post Reply | Private Reply | To 6 | View Replies]

To: TribalPrincess2U

Now I’m wondering why it all can’t be done in the ‘OPEN MRI, if the MRI uses the glucose also.


16 posted on 07/08/2013 6:51:19 PM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 12 | View Replies]

To: TribalPrincess2U

Also on another note: About cancer of the breast.

FIRST: You need to find out if you’re are ‘estrogen receptive positive’.

If you have had a complete hysterectomy and have taken hormones for years and years you are in BIG trouble. One can get by not taking hormones. Don’t think you can’t! Hormones feed the cancer. They did mine. Also I was drinking Soy beverage for several years and soy has flavinoids so it is also bad for ‘estrogen receptive positive’ cancers.


17 posted on 07/08/2013 6:59:00 PM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 16 | View Replies]

To: TribalPrincess2U

i heard that sugar feeds cancer


18 posted on 07/08/2013 7:02:33 PM PDT by GeronL
[ Post Reply | Private Reply | To 17 | View Replies]

To: TribalPrincess2U
Metformim is for Diabetics. How does that relate?

Metformin has been found to reduce cancer rates by 50 to 75% in those taking it.

19 posted on 07/08/2013 7:06:37 PM PDT by aimhigh (Guns do not kill people. Abortion kills people.)
[ Post Reply | Private Reply | To 13 | View Replies]

To: TribalPrincess2U

I, too, was diagnosed with estrogen-positive BC. Prior to diagnosis, I didn’t take hormones of any kind, and I didn’t drink soy beverages. However, for a few years before diagnosis, there was one thing I was consuming in large amounts — SUGAR! :-(

Since then, I try to eat mostly veggies now. But, every once in awhile, I fall off the wagon.


20 posted on 07/08/2013 7:10:05 PM PDT by Tired of Taxes
[ Post Reply | Private Reply | To 17 | View Replies]

To: arichtaxpayer

I was going to say the same-how would this be different than a PET scan? Other than PET scans use radioactive materials—there’s probably more overhead with handling.


21 posted on 07/08/2013 7:18:46 PM PDT by Lou L (Health "insurance" is NOT the same as health "care")
[ Post Reply | Private Reply | To 5 | View Replies]

To: GeronL

I’m not sure I agree with that. Cancers are cells that grow at abnormal rates; because of their growth rate, they use more glucose, which ALL cells do to grow. Using technologies like PET, we can see this more rapid uptake of glucose. This doesn’t mean that “sugars cause cancer.”


22 posted on 07/08/2013 7:23:50 PM PDT by Lou L (Health "insurance" is NOT the same as health "care")
[ Post Reply | Private Reply | To 18 | View Replies]

To: Lou L

Most cancer cells lack the ability to manufacture their own glucose.


23 posted on 07/08/2013 7:24:50 PM PDT by Black Agnes
[ Post Reply | Private Reply | To 22 | View Replies]

To: Lou L

I didnt say it caused cancer.


24 posted on 07/08/2013 7:26:53 PM PDT by GeronL
[ Post Reply | Private Reply | To 22 | View Replies]

To: aimhigh

That’s interesting. My husband takes it for his diabetes.


25 posted on 07/08/2013 7:41:12 PM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 19 | View Replies]

To: aimhigh

That’s interesting. My husband takes it for his diabetes.


26 posted on 07/08/2013 7:41:26 PM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 19 | View Replies]

To: TribalPrincess2U

I am not sure how to do it with humans. We gave our dogs about a tsp a day. But there is much to read on its effects on humans and how to administer it- it will probably be pretty specific for different conditions so you should be able to find what you need easily online. I am so sorry about your health. I have had MRIs and was claustrophobic initially but they were able to inch me in little by little and I gor through it. One friend on FB had to have some medicinal help to get through it and he said it went pretty fast. I listen to music to help with the stress of going through it. Being sick sucks.
If you need to talk, just pm me.


27 posted on 07/08/2013 7:47:25 PM PDT by Cowgirl of Justice
[ Post Reply | Private Reply | To 12 | View Replies]

To: Tired of Taxes

OMG? Sugar. I am a sugar junky also. She didn’t say anything about eating ‘sugar’ I esp. like semi-sweet chocolate. Cakes, cookies. Crap no wonder they say your diet will have to change.

Now with no hormones, hot flashes, no sweets, No more soothing Starbucks, I will become another raging green hulk.

I really wanted to get away from SB anyway. One good thing.


28 posted on 07/08/2013 7:47:31 PM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 20 | View Replies]

To: Cowgirl of Justice

Can one listen to music in PET?


29 posted on 07/08/2013 7:57:50 PM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 27 | View Replies]

To: TribalPrincess2U

I haven’t had a PET. Just MRIs and CAT scans.


30 posted on 07/08/2013 8:02:21 PM PDT by Cowgirl of Justice
[ Post Reply | Private Reply | To 29 | View Replies]

To: Secret Agent Man

the majority of healthcare costs are racked up later in life

cancer mostly inflicts the elderly in society.

the cost of health care is now on the fedgov

therefore, fedgov will never push to cure cancer (or other mostly elderly ailments) as they look to limit costs


31 posted on 07/08/2013 8:03:58 PM PDT by sten (fighting tyranny never goes out of style)
[ Post Reply | Private Reply | To 2 | View Replies]

To: numberonepal
You gotta wonder why the first words from the oncologists mouth after giving patients the bad news isn’t “stop eating sugar to increase your chances of survival”.

Indeed. The amount of evidence that exists to show that cancer feeds on sugars would lead one to the conclusion that anything that drives insulin will promote cancer - to put it in simple terms.

Instead, the first option is, generally, to offer a treatment (chemo) that is, itself, carcinogenic?!?!

32 posted on 07/08/2013 8:09:49 PM PDT by RobertClark (My shrink just killed himself - he blamed me in his note!)
[ Post Reply | Private Reply | To 6 | View Replies]

To: sten

big secret - no cancer cure group wants to cure cancer anyway. if they did they’d push the things that actually do reduce and eliminate cancers.


33 posted on 07/08/2013 8:30:16 PM PDT by Secret Agent Man (Gone Galt; Not averse to Going Bronson.)
[ Post Reply | Private Reply | To 31 | View Replies]

To: TribalPrincess2U; Cowgirl of Justice
What way do you dispense tumeric?
I have bone lesion on my skull. It may have matastisized from the breast cancer.


I'm curious too. Mom has inflammatory breast cancer so I wonder if tumeric can help and how does one use it? Where can one get it? Mom has it in her left breast and a small spot on her lung. BTW, Mom has been through a PET scan too.
34 posted on 07/08/2013 8:59:25 PM PDT by Nowhere Man ("We have met the enemy, he is us!" - Pogo Possum - 1971)
[ Post Reply | Private Reply | To 12 | View Replies]

To: Nowhere Man

Interesting.


35 posted on 07/08/2013 9:08:14 PM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 34 | View Replies]

To: arichtaxpayer
PET scans are this way.

PET scans use labeled 2-fluorodeoxy-D-glucose and expose you to ionizing radiation.

36 posted on 07/08/2013 10:25:47 PM PDT by neverdem (Register pressure cookers! /s)
[ Post Reply | Private Reply | To 5 | View Replies]

To: Nowhere Man

Please research where to get it online. I bought tumeric in the spice aisle at the grocery store but I am sure there are health food stores that have it capsuled up. Also, look at the studies that have been done. What I read gave me hope for our dog and he is doing well. It has been two years since his last surgery and no tumors have popped up.


37 posted on 07/09/2013 4:42:16 AM PDT by Cowgirl of Justice
[ Post Reply | Private Reply | To 34 | View Replies]

To: Black Agnes
Most cancer cells lack the ability to manufacture their own glucose.

I agree. I didn't say cancer cells manufacture glucose; the cells absorb glucose and convert it to energy, to help the cancer cell divide and grow.

38 posted on 07/09/2013 7:02:39 AM PDT by Lou L (Health "insurance" is NOT the same as health "care")
[ Post Reply | Private Reply | To 23 | View Replies]

To: TribalPrincess2U; Nowhere Man

Tribal Princess - I had a PET scan two years ago. They gave me a radioactive tracer to drink and kept me isolated for a bit... I guess so that no one else would be harmed by the tracer. It was a strange experience, but the scan caught what turned out later to be a benign cyst.

I don’t remember being allowed to listen to music or do anything but lie in the position they put me in during the PET scan.

TP and Nowhere Man - Here’s a link to the ACA with more information on turmeric:

http://www.cancer.org/treatment/treatmentsandsideeffects/complementaryandalternativemedicine/herbsvitaminsandminerals/turmeric

I’ve never tried supplementing with turmeric. Maybe now is the time to look into it.


39 posted on 07/09/2013 11:04:15 AM PDT by Tired of Taxes
[ Post Reply | Private Reply | To 29 | View Replies]

To: Tired of Taxes

I’m getting the glucose injection and set for an hour and no stimulations before the scan.

No big deal there. I would like to listen to my ‘Mark Bishop’ music on my Ipod before and during the scan. Probably not.

Mark’s music helps me through the dentist visits.


40 posted on 07/09/2013 11:25:49 AM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 39 | View Replies]

To: TribalPrincess2U

Good luck with everything.


41 posted on 07/09/2013 1:33:05 PM PDT by Tired of Taxes
[ Post Reply | Private Reply | To 40 | View Replies]

To: Tired of Taxes

Thanks, one and all! Tomorrow at 2:45.


42 posted on 07/09/2013 1:44:59 PM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 41 | View Replies]

To: TribalPrincess2U

How did everything go with the scan?


43 posted on 07/10/2013 9:05:19 PM PDT by Tired of Taxes
[ Post Reply | Private Reply | To 42 | View Replies]

To: Tired of Taxes

Thank for asking. It was a PET. I took a Lorazapam and was fine. I opened my eyes a couple times and I think I’m going to get better at this.

Anthony at Radiology Assoc. is great. He helped me through the first whole body bone scan. I was pilled up for that one too.

Next comes the open MRI.


44 posted on 07/11/2013 8:45:23 AM PDT by TribalPrincess2U (0bama's agenda—Divide and conquer seems to be working.)
[ Post Reply | Private Reply | To 43 | View Replies]

To: TribalPrincess2U

Glad to hear the PET scan worked out for you. I hope you find the open MRI to be very comfortable. I will say a prayer for you.


45 posted on 07/11/2013 6:12:18 PM PDT by Tired of Taxes
[ Post Reply | Private Reply | To 44 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson