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New Treatment for Peyronie's Disease Approved by FDA
The FDA ^ | December 6, 2013

Posted on 12/08/2013 8:06:30 AM PST by Lizavetta

FDA approves first drug treatment for Peyronie’s disease

The U.S. Food and Drug Administration today approved a new use for Xiaflex (collagenase clostridium histolyticum) as the first FDA-approved medicine to treat men with bothersome curvature of the penis, a condition known as Peyronie’s disease.

Xiaflex is the first FDA-approved non-surgical treatment option for men with this condition, who have a plaque (lump) in the penis that results in a curvature deformity of at least 30 degrees upon erection.

Peyronie’s disease is caused by scar tissue that develops under the skin of the penis. This scar tissue causes an abnormal bend during erection and can cause problems such as bothersome symptoms during intercourse.

“Today’s approval expands the available treatment options for men experiencing Peyronie’s disease, and enables them, in consultation with their doctor, to choose the most appropriate treatment option,” said Audrey Gassman, M.D., deputy director of the Division of Bone, Reproductive and Urologic Products in the FDA’s Center for Drug Evaluation and Research.

Xiaflex is a biologic medicine (made from the protein product of a living organism, collagenase clostridial histolyticum). Xiaflex was first approved by the FDA in 2010 for the treatment of Dupuytren’s contracture, a progressive hand disease that can affect a person’s ability to straighten and properly use their fingers. Xiaflex is believed to work for Peyronie’s disease by breaking down the buildup of collagen (a structural protein in connective tissue) that causes the curvature deformity.

(Excerpt) Read more at fda.gov ...


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I know two people who have this condition and it's been said Peyronie's is highly unreported because of the embarrassment. I know some here joke about it because Clinton supposedly has it (The Bent One) but it can be a devastating thing to a man. Hopefully, this will help.
1 posted on 12/08/2013 8:06:30 AM PST by Lizavetta
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To: Lizavetta

Yeah with left leaning Bill being the reason I ever heard of it. It makes it hard not to laugh.


2 posted on 12/08/2013 8:11:13 AM PST by Vaquero (Don't pick a fight with an old guy. If he is too old to fight, he'll just kill you.)
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To: Lizavetta

The first leap forward under Obamacare is treatment of Clinton Disease?

I’m not surprised.


3 posted on 12/08/2013 8:18:52 AM PST by Hardraade (http://junipersec.wordpress.com/2013/10/04/nicolae-hussein-obama/)
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To: Lizavetta

Will Bubba do TV ads like Bob Dole did?

“Hi I’m Bubba Clinton and all of my partners know I lean to the left, but sometimes I’d just like to stay middle of the road; that’s when I take “Straight as an Arrow.” SA acts fast and can fool even my favorite DNC girls.”


4 posted on 12/08/2013 8:19:16 AM PST by jmaroneps37 (Conservatism is truth. Liberalism is lies.)
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To: Lizavetta

It might make DIRT-X-POTUS41 a middle-of-the-roader physically, but he remains a serial rapist and his politics always will be bent far to the left.

Oh, and put some ice that...


5 posted on 12/08/2013 8:20:25 AM PST by twister881
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To: Lizavetta
Went to the link and it hurt just reading the article, especially side effects and risks.
Reminds me of being in Vietnam and getting lectured that the cures for some of the exotic forms of VD were worse than the disease.
Owwwwwwwwwwwwwwwww ...
6 posted on 12/08/2013 8:21:25 AM PST by oh8eleven (RVN '67-'68)
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To: Hardraade

Actually, the maker of Xiaflex has been trying to get this approved for many years, long before the Kenyan.


7 posted on 12/08/2013 8:21:49 AM PST by Lizavetta
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To: oh8eleven
Went to the link and it hurt just reading the article, especially side effects and risks.

They have to lay it all out, no matter how slight the risks. I know a top notch urologist in southern California who is the leader in this field and he is very excited about this product.

8 posted on 12/08/2013 8:24:10 AM PST by Lizavetta
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To: Pontiac

for later


9 posted on 12/08/2013 8:28:57 AM PST by Pontiac (The welfare state must fail because it is contrary to human nature and diminishes the human spirit.)
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To: Lizavetta

And it hurts like hell. Not really something to laugh about.

Although, here is was...newly married. I had to get an ultrasound of my penis. I am laid out on my back. The tech is lumbering it up, and running the wand up and down. In comes the group of new RN students. And my high school girlfriend is amongst the students.

I never had eye contact like this with that girl in two years of dating.

I laugh now. But at an early age I learned there is no such thing as personal pride in the hospital.


10 posted on 12/08/2013 8:34:12 AM PST by Vermont Lt (If you want to keep your dignity, you can keep it. Period........ Just kidding, you can't keep it.)
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To: Lizavetta

There once was a man from Kent
Who had one so long that it bent...


11 posted on 12/08/2013 8:52:58 AM PST by Hugh the Scot
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To: onedoug

Harry the hook.


12 posted on 12/08/2013 9:01:01 AM PST by windcliff
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To: Vermont Lt

LOL. When I was in the hospital I was joking with a young aid about embarrassment. She said something like “If you’re shy and you’re in the hospital.....” I finished with “Get over it.”


13 posted on 12/08/2013 9:03:34 AM PST by Enterprise ("Those who can make you believe absurdities can make you commit atrocities." Voltaire)
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To: Lizavetta

Peyronie’s disease is different in character from a similar condition called chordee, which also results in the unusual curvature of the penis.

The latter condition is associated with untreated gonorrhea, in which pustules form in the urethra, which when they reduce leave behind scarring, which causes the curvature. The near future may result in many more cases, because of the appearance of drug resistant gonorrhea.


14 posted on 12/08/2013 9:07:02 AM PST by yefragetuwrabrumuy (Last Obamacare Promise: "If You Like Your Eternal Soul, You Can Keep It.")
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To: Lizavetta
The Rapist will be pleased.
15 posted on 12/08/2013 9:09:11 AM PST by E. Pluribus Unum (Who knew that one day professional wrestling would be less fake than professional journalism?)
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To: Hugh the Scot

... to avoid any trouble
he folded it double...


16 posted on 12/08/2013 9:10:09 AM PST by null and void (I'm betting on an Obama Trifecta: A Nobel Peace Prize, an Impeachment, AND a War Crimes Trial...)
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To: Lizavetta

Lots of penis posts today. Must be the cold.


17 posted on 12/08/2013 9:11:45 AM PST by blueunicorn6 ("A crack shot and a good dancer")
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To: oh8eleven

I remember hearing that if you caught the “Black syf”
they just quarrantined you in vietnam til you rotted
to death. As a precautionary measure I’m sure, althought
that was before AIDS did away with precaution.


18 posted on 12/08/2013 9:13:32 AM PST by tet68 ( " We would not die in that man's company, that fears his fellowship to die with us...." Henry V.)
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To: null and void

Bennet ? Bennet? Hell, I broke it...

Amazing how you can remember the punch lines from juvenile
jokes after so many years.


19 posted on 12/08/2013 9:15:17 AM PST by tet68 ( " We would not die in that man's company, that fears his fellowship to die with us...." Henry V.)
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To: blueunicorn6

If that was the case they would be SMALL jokes.


20 posted on 12/08/2013 9:16:47 AM PST by tet68 ( " We would not die in that man's company, that fears his fellowship to die with us...." Henry V.)
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To: blueunicorn6
Lots of penis posts today. Must be the cold.

You'd think the audience would shrink from that.

21 posted on 12/08/2013 9:29:24 AM PST by Max in Utah (A nation can survive its fools, and even the ambitious. But it cannot survive treason from within.)
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To: tet68
I remember hearing that if you caught the “Black syf” they just quarrantined you in vietnam til you rotted to death.
Yes, an entire island of lost souls. And you KNOW which body part rotted off first. LOL ...
Did NOT want to end up there!
22 posted on 12/08/2013 9:39:20 AM PST by oh8eleven (RVN '67-'68)
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To: null and void

There once was a man from Nantucket.....

Heard about the black syph aka Superclap in Vietnam. Those afflicted were consigned to the Con Son Island tiger cages, we were told.


23 posted on 12/08/2013 10:17:24 AM PST by elcid1970 ("In the modern world, Muslims are living fossils.")
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To: oh8eleven

Thank heavens I saved my self from that, imagine my
surprise when I caught the clap from the first hippie
girl I slept with. Haha jokes on me.


24 posted on 12/08/2013 10:20:45 AM PST by tet68 ( " We would not die in that man's company, that fears his fellowship to die with us...." Henry V.)
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To: Vaquero
Image Hosted by ImageShack.us
25 posted on 12/08/2013 10:23:48 AM PST by vox_freedom (America is being tested as never before in its history. May God help us.)
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To: tet68; blueunicorn6

26 posted on 12/08/2013 10:27:32 AM PST by ErnBatavia (The 0baMao Experiment: Abject Failure)
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To: tet68

Funny; last night I watched SNL and they had a skit about michaelangelo. He was revealing his David statue and the model was there, and it was all about the size of his life model. Sounds dumb but I was laughing.


27 posted on 12/08/2013 10:29:10 AM PST by Yaelle
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To: tet68
I caught the clap from the first hippie girl I slept with.
I rotated summer of '68 and the first Mass I went to turned out to be a folk Mass. Dirty, pinko-commie, hippies right up front adjacent to the altar.
One of many reasons I'm a lapsed Catholic.
28 posted on 12/08/2013 10:30:36 AM PST by oh8eleven (RVN '67-'68)
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To: ErnBatavia

29 posted on 12/08/2013 10:50:00 AM PST by Vaquero (Don't pick a fight with an old guy. If he is too old to fight, he'll just kill you.)
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To: ErnBatavia

30 posted on 12/08/2013 10:52:05 AM PST by Vaquero (Don't pick a fight with an old guy. If he is too old to fight, he'll just kill you.)
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To: Vaquero
Each treatment cycle consists of two Xiaflex injection procedures (in which Xiaflex is injected directly into the collagen-containing structure of the penis)

Ouch!!!

31 posted on 12/08/2013 10:55:50 AM PST by aimhigh
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To: Lizavetta

I was involved in the testing of this treatment method several years ago and I can say from my experience that it does work. At least it did for me. I had tried another treatment method earlier and it didn’t work. However, since the treatment was regarded as experimental I was banned from donating blood for a full year following the treatments.

The description of the treatment in the article was quite accurate; however, it left some parts out. For two weeks following the injections I was required to stretch and bend my penis in order to straighten it. This had to be done daily. I also was barred from sexual activity for a week following the injections.

Even with all of this it was well worth it.


32 posted on 12/08/2013 11:07:29 AM PST by reg45 (Barack 0bama: Implementing class warfare by having no class.)
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To: Lizavetta

My urologist, Dr. Laurence Levine, Rush Medical Ctr., Chicago, IL, was involved in the testing also. I would recommend him to anyone suffering from Peyronie’s Disease.

Dr. Levine is widely regarded as one of the top experts in this condition in the country, if not the world. He has written at least two books on the subject. One for physicians and one for patients.


33 posted on 12/08/2013 11:18:18 AM PST by reg45 (Barack 0bama: Implementing class warfare by having no class.)
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To: windcliff

You had to remind me….


34 posted on 12/08/2013 1:09:29 PM PST by onedoug
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To: elcid1970; null and void

it’s true. We’re all 12 on the inside...


35 posted on 12/08/2013 5:44:57 PM PST by Hugh the Scot
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To: Hugh the Scot

More like 10...


36 posted on 12/08/2013 6:04:20 PM PST by null and void (I'm betting on an Obama Trifecta: A Nobel Peace Prize, an Impeachment, AND a War Crimes Trial...)
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