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Indian scientist develops potential non-insulin diabetes drug
The Financial Express ^ | 04/02/14 | The Financial Express (doesn't say)

Posted on 04/03/2014 7:56:42 PM PDT by Pining_4_TX

"We find that there is a peptide hormone in the gut called GLP1 that increases the secretion of insulin only when the blood glucose is high. This effectively eliminates the risk of hypoglycemic shock. Another advantage is that GLP1 administration has been found to stimulate weight-loss. The hormone offers the promise of revolutionising the treatment of Type II diabetes and reduce obesity," he said.

(Excerpt) Read more at financialexpress.com ...


TOPICS: Health/Medicine
KEYWORDS: diabetes; drugs; glp1; type2diabetes

1 posted on 04/03/2014 7:56:42 PM PDT by Pining_4_TX
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To: neverdem

Please let others know who might be interested in this article. Thanks!


2 posted on 04/03/2014 7:57:28 PM PDT by Pining_4_TX (All those who were appointed to eternal life believed. Acts 13:48)
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To: Pining_4_TX

Thanx

Type 2


3 posted on 04/03/2014 8:09:12 PM PDT by morphing libertarian
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To: Pining_4_TX

Half-life of two minutes makes it really difficult to be useful...


4 posted on 04/03/2014 8:13:16 PM PDT by Domandred (Fdisk, format, and reinstall the entire .gov system.)
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To: Domandred

Yes, but that is what they are attempting to solve, and they seem to have made progress toward that end.

Hope springs eternal, as they say. :-)


5 posted on 04/03/2014 8:16:34 PM PDT by Pining_4_TX (All those who were appointed to eternal life believed. Acts 13:48)
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To: Pining_4_TX

If this turns out to be true, it is a great discovery.


6 posted on 04/03/2014 8:22:12 PM PDT by tbw2
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To: tbw2

Yes it would. I keep hoping for something that gives us more than just healthier mice. ;-)


7 posted on 04/03/2014 8:24:48 PM PDT by Pining_4_TX (All those who were appointed to eternal life believed. Acts 13:48)
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To: tbw2

Exactly, hope this comes to America.


8 posted on 04/03/2014 8:26:16 PM PDT by Patriot Babe
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To: Pining_4_TX

It’s a huge industry killer. Just imagine if they could end type II with a single weekly pill that not only lowers your blood sugar, but reduces your weight and makes you healthier?

I hope these scientists don’t find themselves on a dissapearing 777.


9 posted on 04/03/2014 8:34:22 PM PDT by Dogbert41 (Up yours NSA !)
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To: Dogbert41

“I hope these scientists don’t find themselves on a dissapearing 777.”

Now that’s a disturbing thought.


10 posted on 04/03/2014 8:38:29 PM PDT by Pining_4_TX (All those who were appointed to eternal life believed. Acts 13:48)
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To: Pining_4_TX

Wonderful news he should win Nobel Prize.


11 posted on 04/03/2014 8:42:05 PM PDT by Ciexyz
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To: Pining_4_TX

Interesting development.... worth keeping an eye on


12 posted on 04/03/2014 8:59:54 PM PDT by Nifster
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To: Pining_4_TX
Another advantage is that GLP1 administration has been found to stimulate weight-loss.

Patient compliance would be astronomically high.

13 posted on 04/03/2014 9:59:15 PM PDT by TigersEye (Stupid is a Progressive disease.)
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To: Pining_4_TX

This article is a joke. GLP-1 (glucagon like polpypetide 1) was discovered about 25 years ago. It lowers blood sugar and the human gut secretes it naturally, but it has a short half-life, because it is inactivated by DPP4 (dipeptidyl peptidase 4), another naturally occurring enzyme in the human body. Januvia (by Merck) was the first DPP-4 inhibitor, used to block the DPP-4 enzyme’s degradation of GLP-1, thus lowering blood sugar. Next came a natural mimetic (copy) of GLP-1, Byetta, and it’s analog (synthetic) twin Bydureon, both owned by Astra Zeneca. These drugs came out in the mid 2000’s. Another GLP-1 analog, Victoza (from Novo Nordisk) came out in 2010. There are also a host of Januvia copies on the market (saxagliptin, alogliptin, linogliptin,etc.). Before you start thinking this is a new breakthrough, educate yourselves on the diabetes therapies.


14 posted on 04/03/2014 10:30:15 PM PDT by Panzerfaust
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To: Panzerfaust

LOL, threatened much?

With all your big words, you think there’s been no progress since the mid-2000’s?

Or is it that you think that research should just stop where it is, because there’s nothing left to discover or develop?

Or, rather, have your employers told you to squelch hope for your 13 coins of silver?


15 posted on 04/03/2014 10:33:57 PM PDT by Talisker (One who commands, must obey.)
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To: Patriot Babe

We have it. It’s called Byetta.

Not sure how this is any different. They’re both GLP-1.


16 posted on 04/04/2014 6:12:04 AM PDT by Marie (When are they going to take back Obama's peace prize?)
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To: Talisker

No, he’s right. This is old news.


17 posted on 04/04/2014 6:13:00 AM PDT by Marie (When are they going to take back Obama's peace prize?)
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To: Marie
No, he’s right. This is old news.

No, I'm right. The posted date is April 2. That means my points stand. Thanks for playing.

18 posted on 04/04/2014 10:51:39 AM PDT by Talisker (One who commands, must obey.)
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To: Talisker

GLP-1 as a treatment for diabetes is old news. This ‘discovery’ is a crock. This would be like someone crowing that they’ve discovered insulin.

Not only has it already been discovered, it’s been tested, developed into a medication, is already on the market, and covered by insurance.

I see where you found the article interesting and wanted to pass it on. I don’t see why this would anger anyone. It was presented as a discovery and you didn’t know. No big deal.

But the fact is, GLP-1 for the treatment of diabetes has been around for awhile. That’s just a fact.


19 posted on 04/04/2014 11:11:38 AM PDT by Marie (When are they going to take back Obama's peace prize?)
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To: Marie

You need to contact the researchers in this field - they have no idea the science is settled and no further development is possible. Please save them from unavoidable terminal frustration, not to mention all the continuously wasted tax dollars. It’s your duty to Truth.


20 posted on 04/04/2014 12:47:28 PM PDT by Talisker (One who commands, must obey.)
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To: Panzerfaust

When I see articles that could be of interest to Freepers concerned about diabetes, I post them. My hope is that the information generates discussion with pros and cons, because there is a lot out there about diabetes and not all of it is accurate.

So, I do appreciate your knowledgeable comment... well, except perhaps the snarky last line.


21 posted on 04/05/2014 10:30:56 AM PDT by Pining_4_TX (All those who were appointed to eternal life believed. Acts 13:48)
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To: Pining_4_TX

I really hate mice. they can be cured of almost anything,
in addition to the other reasons.


22 posted on 04/29/2014 5:03:20 AM PDT by cycjec
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To: cycjec

Ha, ha, I agree! And they never have to worry about finding clothes that fit. ;-)


23 posted on 05/06/2014 11:41:08 AM PDT by Pining_4_TX (All those who were appointed to eternal life believed. Acts 13:48)
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