[C. Edmund Wright]

In my opinion, there is only one running 'gag' and its name is Sheldon Cooper.

There's no show without him, as played by Jim Parsons. I've heard that the actor playing Leonard was the original cast for Sheldon, and that he insisted they hire Parsons. I think that actor Johnnie Gilecki is the weak link in the show, but give him credit for that suggestion! Also, FWIW, I think the best comedic timing by far goes to Wolowicz….

[prof.h.mandingo]

I think Gilecki works in that he is the foil for Parsons. Think the famous straight men like Abbot to Costello. I do agree Sheldon makes the show. And I could not see it with Gilecki as the “Sheldon” character.