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A 100-year-old drug corrects autistic social behaviors in lab tests
The Verge ^ | 06/17/2014 | Arielle Duhaime-Ross

Posted on 06/17/2014 9:09:49 AM PDT by Rusty0604

In the study, researchers administered a dose of suramin to 25 male mice, whereas another 25 males received a saline injection instead. All mice were "maternal immune activation mouse models," meaning animals that exhibit autism-like behaviors following a virus infection in their mothers during pregnancy. This single dose, the researchers report, corrected the social behaviors seen in autism spectrum disorder. The mice, for instance, spent more time interacting with both mice and objects they had never interacted with before, compared to those injected with a saline solution. The benefits lasted for five weeks after the drug was washed out of their system.

(Excerpt) Read more at theverge.com ...


TOPICS: Health/Medicine
KEYWORDS: autism
"following a virus infection in their mothers during pregnancy"...?
1 posted on 06/17/2014 9:09:49 AM PDT by Rusty0604
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To: Rusty0604

These drugs — be they for Cancer, Parkinsons or Alzheimer’s and now, autism are great— if you’re a mouse.


2 posted on 06/17/2014 9:12:18 AM PDT by SeekAndFind
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To: Rusty0604

Autistic MICE?


3 posted on 06/17/2014 9:12:57 AM PDT by Cyman (We have to pass it to see what's in it= definition of stool sample)
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To: Cyman

they won’t look you in the eye


4 posted on 06/17/2014 9:14:53 AM PDT by babble-on
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To: Cyman

The report refers very carefully to “autism-like behaviors,” not autism as experienced in humans.


5 posted on 06/17/2014 9:15:01 AM PDT by EDINVA
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To: Cyman

I have a 22 year old Autistic son. I also have several library shelves of books about Autism, spanning a couple of decades.

At this point, for whatever purpose, my son is what he is.

He is possibly the happiest person I have ever known.


6 posted on 06/17/2014 9:17:21 AM PDT by the anti-mahdi
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To: Rusty0604

A few year’s ago, my friend’s daughter was diagnosed as mildly autistic. My friend, a nurse, worked overtime hours to get the child good private therapy. Today, the girl is perfectly normal.


7 posted on 06/17/2014 9:30:10 AM PDT by CatherineofAragon ((Support Christian white males---the architects of the jewel known as Western Civilization).)
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To: the anti-mahdi

I don’t know much about autism, but if they are coming up with drugs by injecting mother mice with a virus causing autistic symptoms that sounds scary.


8 posted on 06/17/2014 9:56:35 AM PDT by Rusty0604
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To: Rusty0604

Strong stuff.

“The most frequent adverse reactions are nausea and vomiting. About 90% of patients will get an urticarial rash that disappears in a few days without needing to stop treatment. There is a greater than 50% chance of adrenal cortical damage, but only a smaller proportion will require lifelong corticosteroid replacement. It is common for patients to get a tingling or crawling sensation of the skin with suramin. Suramin will cause clouding of the urine which is harmless: patients should be warned of this to avoid them becoming alarmed.”

http://en.wikipedia.org/wiki/Suramin

http://en.wikipedia.org/wiki/Urticaria


9 posted on 06/17/2014 10:30:06 AM PDT by yefragetuwrabrumuy ("Don't compare me to the almighty, compare me to the alternative." -Obama, 09-24-11)
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To: the anti-mahdi

Lord, help me to know Your Will for me today,
And help me to desire it.

GBU!


10 posted on 06/17/2014 10:38:03 AM PDT by If You Want It Fixed - Fix It
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To: Rusty0604

I would be diagnosed with autistic spectrum disorder if I were young. My younger boy would probably also be diagnosed if we wanted him diagnosed. I suspect that there is a genetic predisposition.

That being said, I didn’t really become aware of how odd I seemed until I was an adult. I can overcome the most of the social miscues if I’m careful and I’m trying teach the same to my son.

It is difficult interacting with people but the deficit seems to be balanced with a proficiency in non verbal skills.

I’m not sure I would want to take a drug to make me “normal”


11 posted on 06/17/2014 10:39:09 AM PDT by dangerdoc ((this space for rent))
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To: Rusty0604

Also, using male mice has problems with stress related issues because male mice are stressed by the lab technician if a male.

http://www.huffingtonpost.com/2014/04/30/male-scent-biomedical-research-video_n_5239582.html


12 posted on 06/17/2014 10:49:51 AM PDT by huldah1776
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To: If You Want It Fixed - Fix It

Thank you. May God bless you and keep you in His grace. Life is hard. Well, anyone that has not yet learned that it is, will.

We’ll meet people after, and we’ll know who they are and it will be a family reunion with God.


13 posted on 06/17/2014 11:36:02 AM PDT by the anti-mahdi
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To: CatherineofAragon

A good friend of mine had a daughter diagnosed as autistic and retarded in CA about 25 years ago. The school district wanted to warehouse her into Special Ed.

He and his wife homeschooled her instead. She gained admittance at 18 into an elite college and graduated from it near the top of her class.

Incidentally, at that time for the state to allow them to homsechool her both John and his wife had to pass the state teacher’s exam. They both said it was the easiest test they’d ever taken in their lives.


14 posted on 06/17/2014 11:37:57 AM PDT by Sherman Logan (Perception wins all the battles. Reality wins all the wars.)
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To: Sherman Logan

I have no problem believing that about the CA exam.

I could very well be wrong, but it’s my impression the guidelines of what autism IS are murky. I wonder how many times children are misdiagnosed when, in fact, they don’t have a problem at all.


15 posted on 06/17/2014 11:52:14 AM PDT by CatherineofAragon ((Support Christian white males---the architects of the jewel known as Western Civilization).)
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To: CatherineofAragon

They are so murky that the PC term is now “autism spectrum disorder.” IOW, “autism,” to the extent the term means anything at all, describes a huge range of disorders or oddities of behavior.

I have no doubt it exists, but I also have no doubt it is presently being wildly over-diagnosed.


16 posted on 06/17/2014 12:14:40 PM PDT by Sherman Logan (Perception wins all the battles. Reality wins all the wars.)
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To: Sherman Logan

Your description brings to mind all the ADHD diagnoses...


17 posted on 06/17/2014 1:11:08 PM PDT by CatherineofAragon ((Support Christian white males---the architects of the jewel known as Western Civilization).)
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