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Can heart attack damage be reversed?
CNN ^ | July 12, 2014 | Caleb Hellerman

Posted on 07/12/2014 8:51:48 PM PDT by Innovative

An hour's drive to the southeast, at Cedars-Sinai Medical Center in Los Angeles, Dr. Eduardo Marban has recently launched an experiment to help patients like Karpman.

Marban led one of the earlier stem cell trials, using cells taken by biopsy from the patient's own heart. The cells were multiplied in a laboratory for two to three weeks and then reinfused through a catheter. At the time, says Marban, it was thought that the stem cells themselves turned into new heart muscle and blood vessels.

"In fact, the more we learned, the more we realized that that's not what these cells do," he says. "They can make heart muscles and blood vessels in a dish very nicely. But in the living organism what they seem to do is secrete factors that wake up the surrounding heart muscle."

Like re-charging a battery, the infusion of new cells seems to trigger the body to produce new tissue: new muscle and blood cells.

(Excerpt) Read more at cnn.com ...


TOPICS: Health/Medicine
KEYWORDS: heart; heartattack; medicaldiscovery; medicine; stemcells
This is quite a discovery and can save and improve many lives.
1 posted on 07/12/2014 8:51:49 PM PDT by Innovative
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To: Innovative

With heart muscle always considered unable to re-grow or rejuvenate itself, if this is true, it is a big, big deal.


2 posted on 07/12/2014 8:53:36 PM PDT by KC Burke (Gowdy for Supreme Court)
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To: KC Burke

Read the article, it gives more details and looks solid.


3 posted on 07/12/2014 8:54:07 PM PDT by Innovative ("Winning isn't everything, it's the only thing." -- Vince Lombardi)
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>> Marban led one of the earlier stem cell trials,

Thankfully Obama reversed Bush’s order restricting vital embryonic stem cell research...

Political sarcasm aside, good news.


4 posted on 07/12/2014 8:57:29 PM PDT by Gene Eric (Don't be a statist!)
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To: KC Burke

A renewal of heart.


5 posted on 07/12/2014 9:03:55 PM PDT by HiTech RedNeck (Embrace the Lion of Judah and He will roar for you and teach you to roar too. See my page.)
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To: Innovative

Good news, especially now that I’m hearing for the first time today that after years of being told that a glass or two of red wine each day is good for the blood pressure and heart, such is not the case and in fact can be damaging if used even in moderation......


6 posted on 07/12/2014 9:05:28 PM PDT by Intolerant in NJ
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To: Innovative

I hope it works for brain tissue! I had my son’s chord blood saved 13 years ago - it should be a match.


7 posted on 07/12/2014 9:06:41 PM PDT by uncommonsense (Liberals see what they believe; Conservatives believe what they see.)
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To: KC Burke

Major breakthrough, indeed.


8 posted on 07/12/2014 9:11:02 PM PDT by GladesGuru (Islam Delenda Est. Because of what Islam is - and for what Muslims do.)
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To: Intolerant in NJ

I cry BS on that. Throw a bottle of Blackberry wine or cold bear in a snow bank. See if that doesn’t help your disposition.


9 posted on 07/12/2014 9:21:49 PM PDT by OftheOhio (never could dance but always could kata - Romeo company)
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To: Innovative

I remember watching a TV shoe called “The Bold Ones” (1969 - 1973) where they had the episode of the “New Doctors” (it was a show that rotated between doctors, policeman, lawyers and a senator) from 1969 where part of the plot was using a patient’s own stem cells to regrow and repair damaged hear muscle what was very experimental then and maybe now. It starred E.G. Marshall as head of the research hospital and John Saxon and David Hartman played the doctors helping him.


10 posted on 07/12/2014 9:32:21 PM PDT by Nowhere Man (Mom I miss you! (8-20-1938 to 11-18-2013) Cancer sucks)
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To: Nowhere Man

shoe = show


11 posted on 07/12/2014 9:33:17 PM PDT by Nowhere Man (Mom I miss you! (8-20-1938 to 11-18-2013) Cancer sucks)
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To: Innovative

Hearts - the next stage of the 3D printing revolution: This medical miracle is shockingly close
http://www.freerepublic.com/focus/f-news/3117604/posts

A Fully Functional 3-D Printed Heart Sooner Than You Think
http://www.freerepublic.com/focus/f-news/3145522/posts

The next frontier in 3-D printing: Human organs
http://www.freerepublic.com/focus/f-news/3140679/posts


12 posted on 07/12/2014 9:35:36 PM PDT by 2ndDivisionVet (The most dangerous man to any government is the man who is able to think things out for himself.)
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To: Gene Eric

These are not embryonic stem cells — he initially used stem cells from the patients’ own hearts, now stem cells from the hearts of organ donors.


13 posted on 07/12/2014 9:43:23 PM PDT by Innovative ("Winning isn't everything, it's the only thing." -- Vince Lombardi)
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To: Intolerant in NJ

” a glass or two of red wine each day is good for the blood pressure and heart, such is not the case and in fact can be damaging if used even in moderation......”

I haven’t heard that red wine is damaging, quite the opposite — most research shows it’s healthy. I would be cautious if one study shows it’s not.

If you have a reference and wouldn’t mind posting it, I’d appreciate it.


14 posted on 07/12/2014 9:45:48 PM PDT by Innovative ("Winning isn't everything, it's the only thing." -- Vince Lombardi)
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To: Intolerant in NJ

“after years of being told that a glass or two of red wine each day is good for the blood pressure and heart, such is not the case and in fact can be damaging if used even in moderation......”

Since you mentioned you read it today, I googled it and found it:

Study: Light Drinking Of Alcohol Not Good For Heart

http://atlanta.cbslocal.com/2014/07/12/study-light-drinking-of-alcohol-not-good-for-heart/

It is highly misleading — they didn’t do their own study, but reviewed several others and even the article mentions:

“What they found was that those who possessed a gene tied to lower alcohol consumption generally had healthier hearts.”

So there is a genetic component to it — some have “better” genes.

And in the article I posted to start this thread, the patient whose experience they were describing was a man who ran regularly, ate no meat and still had a heart attack.

I think there is still a great deal more evidence that a glass of wine and some dark chocolate are good for you.


15 posted on 07/12/2014 9:53:17 PM PDT by Innovative ("Winning isn't everything, it's the only thing." -- Vince Lombardi)
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To: Innovative

But, But, George Bush stopped stem cell research because he wanted people to die of curable illnesses. Christopher Reeves would be walking today except for George Bush!

Oldplayer


16 posted on 07/12/2014 9:54:54 PM PDT by oldplayer
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To: KC Burke
With heart muscle always considered unable to re-grow or rejuvenate itself, if this is true, it is a big, big deal.

Yes indeedy! Let's move on to brain tissue!

17 posted on 07/12/2014 10:02:20 PM PDT by To Hell With Poverty (Ephesians 6:12 becomes more real to me with each news cycle.)
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To: Gene Eric

This has been going on for a while now ...right through the Bush years when he “outlawed progress”

Ive been watching it for a while as I would like to get it


18 posted on 07/12/2014 10:08:18 PM PDT by woofie
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To: Innovative

Amazing


19 posted on 07/12/2014 10:17:58 PM PDT by patriot08 (NATIVE TEXAN (girl type))
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To: Innovative

I hope, though it’s probably in vain, that Obamacare doesn’t destroy American medical innovation.

And it said that this patient is back to walking 4 miles a day. Like he was thin and walking 4 miles a day before his heart attack. Whew! I thought that being thin and exercising would pretty much preclude having heart problems but I guess not.

Anyway, how cool that this procedure is being tried and I sure hope that it’s successful.


20 posted on 07/12/2014 10:32:30 PM PDT by bluedogpdx
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To: woofie

Well, you know one place where they are doing it, there might be other medical centers around the country as well.

“An hour’s drive to the southeast, at Cedars-Sinai Medical Center in Los Angeles, Dr. Eduardo Marban has recently launched an experiment to help patients like Karpman. “


21 posted on 07/12/2014 10:46:50 PM PDT by Innovative ("Winning isn't everything, it's the only thing." -- Vince Lombardi)
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To: Innovative

I read the article. It doesn’t give much detail regarding obtaining stem cells from the patient’s own heart. If that entailed invasive open-heart surgery It would seem to me to be a risky route. It also said stem cells could be obtained from donor organs. I thought there was an acute shortage of those; still, this might be a breakthrough.


22 posted on 07/12/2014 10:47:22 PM PDT by luvbach1 (We are finished. It will just take a while before everyone realizes it.)
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To: luvbach1

” I thought there was an acute shortage of those; still, this might be a breakthrough.”

I think there is indeed a shortage of donor organs — as in transplanting entire organs, but the way I read it, they can save a lot of stem cells from one organ and you need only a small amount, so you can help a lot of people with the stem cells from one donor heart.


23 posted on 07/12/2014 10:58:37 PM PDT by Innovative ("Winning isn't everything, it's the only thing." -- Vince Lombardi)
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To: Innovative

Bookmark


24 posted on 07/13/2014 12:23:56 AM PDT by aquila48
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To: Innovative
I'll live forever and vote Conservative tooooooo, for ETERNITY!!

Or someone else will vote for me after I croak.

25 posted on 07/13/2014 12:29:49 AM PDT by MaxMax (Pay Attention and you'll be pissed off too! FIRE BOEHNER, NOW!)
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To: Innovative

Superficial conclusions made in that article.


26 posted on 07/13/2014 1:07:56 AM PDT by Gene Eric (Don't be a statist!)
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To: Innovative
...they can save a lot of stem cells from one organ and you need only a small amount, so you can help a lot of people with the stem cells from one donor heart.

Thanks for the clarification. I would think that would also be a safer alternative than harvesting the stem cells from the heart patient him/herself for obvious reasons.

27 posted on 07/13/2014 1:16:06 AM PDT by luvbach1 (We are finished. It will just take a while before everyone realizes it.)
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To: Innovative

Really ? The research to date has been very mixed with quite a number of investigations that haven’t found a protective effect for red wine or other alcohol, probably because of the difficulty of doing studies in which people often do not tell scientists and doctors how much they really drink. The Penn results are just the largest sample showing significant harm to the heart in even moderate intake. The genetic component was due to not being able to tolerate alcohol, not better genes overall. I may or may not discontinue my habit of 2-3 oz of red wine a day (60-70 ml?) but it is good to know this just seems to be another case where you get a lot of hype about health benefits that doesn’t stand the test of time.


28 posted on 07/13/2014 2:23:07 AM PDT by erlayman
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To: To Hell With Poverty

Should work but the brain has many parts, different types of nerve cells, and the blood-brain barrier protects it. Hyperbaric Oxygen therapy has been shown to improve brain function and there is a movement to offer this to our vets outside of the VA. The government is only doing studies now, but outside there have been many. In Europe they do not use pure oxygen because of the damage, if I remember right, from long-term or overdose use.

The heart also has brain cells, so could they use the patients heart-brain cells for the brain?

No meat didn’t help the guy.

One interesting article I read this week was of a woman whose cells formed a nose 8 years after they were planted-on her back.

http://www.dailymail.co.uk/health/article-2685842/Stem-cell-patient-grows-NOSE-eight-years-treatment-cure-paralysis-failed.html


29 posted on 07/13/2014 6:18:00 AM PDT by huldah1776
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To: erlayman

I wonder if it has anything to do with alcohol tolerance. The heart has brain cells in it. Males and females have different tolerances, too. I would think when it comes to what we eat, we should follow our ancestor’s diet. If they live a long time, do what they did. If you are of mixed heritage, good luck. Gene studies will someday tell you what you are good for. The one thing I learned about genes that I didn’t know is some can turn on and off.


30 posted on 07/13/2014 6:30:21 AM PDT by huldah1776
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To: erlayman

Sorry about missing the tolerance statement in your post. Must be having a low sugar crash. Too much maple syrup in my oatmeal? Get loopy. When I re-read your post I realized I wasn’t far off. Better go get some meat to offset my sugar.


31 posted on 07/13/2014 6:33:47 AM PDT by huldah1776
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To: Innovative

Good that you found the study - I hadn’t read it but heard it discussed by a physician as part of a Fox News program on medical news - there was a genetic component to the effects as you noted - but that said, I have to acknowledge that my own cardiologist told me a couple of years ago to limit wine consumption to six ounces per day, since more alcohol than that could damage heart muscle - I don’t always stay within limits, but I have tried to cut back some - as my wife says, “as long as a moderate amount doesn’t hurt, what’s wrong with it?” - and there’s always the positive psychological effect of having a nice sip of wine now and then to civilize things.....


32 posted on 07/13/2014 8:58:50 PM PDT by Intolerant in NJ
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