Skip to comments.Type 1, Type 2 Diabetes Share Underlying Mechanism
Posted on 08/20/2014 8:42:35 PM PDT by Pining_4_TX
Work by scientists at the Universities of Manchester and Auckland suggest that both major forms of diabetes, type 1 and type 2, are the result of the same mechanism.
The findings, published in the FASEB Journal, provide compelling evidence that juvenile-onset or type 1 diabetes and type 2 diabetes are both caused by the formation of toxic clumps of a hormone called amylin.
The results, based on 20 years work in New Zealand, suggest that type 1 and type 2 diabetes could both be slowed down and potentially reversed by medicines that stop amylin forming these toxic clumps.
(Excerpt) Read more at biosciencetechnology.com ...
Maybe in 5 years of so they might have a cure.
Wouldn’t that be wonderful? I pray for that.
Type II Diabetes runs rampant in my family. I’m the Last One Standing. Grandparents on both sides had it. Dad has it. Sister has it. Many cousins have it.
My answer is simple. I walk a lot. I do, ‘push-aways’ from the dinner table and I back off the booze and the Twinkies.
If it’s genetic, you do what needs to be done.
That is fantastic news about this silent killer.
Many sufferers played absolutely no part getting this malady.
Unfortunate kids who get it as adolescents, for example.
If it works, it’s a long way off, but it would seem important in understanding the disease.
Thanks for posting this.
Just like the long and costly scourge of ulcers which were eliminated very simply, diabetes may soon be only a memory.
True, but I hate to be the bearer of bad news, one can do all that and the disease will probably still progress. Our bodies break down with age, and for people with diabetes, the pancreas deterioriates faster than it does for others. Some people die at a ripe old age of cancer, some of heart disease, and some of diabetes. Nobody dies of nothing.
You might be interested in a blog by David Mendoza. He controls his type 2 with a low carb diet and exercise.
Again, though, diabetes is progressive in nature, and unless researchers come up with a genuine cure, as opposed to all the medications now that treat the symptoms and may or may not forestall the complications, that is probably what will get diabetics before something else does. :-(
You’re welcome. :-)
I don’t believe that being over weight “causes’’ diabetes. It might make it come on a little sooner, but extra fat doesn’t cause pancreatic failure. I think it’s more the reverse because it’s the job of the pancreas to help with digesting fats. If it’s in failure, it can’t do that very well.
Anyway, it really would be a huge blessing to many if a cure was found.
I was a very young adult when it happened upon me, and I wasn’t over weight. Some docs say I’m type 1, but those who cater to the party line automatically decided it was type 2 simply because I happen to be older now...sheesh.
Other than genetics, I’d still like to know what causes it.
what causes the malfunction in the first place. Being genetically predisposed is one thing, but is there a trigger like a virus or childhood disease or mold or dust or something? Is it a food additive that triggers it. Something has to trigger it.]
Oh, I understand that. It’s just that others in my family prefer to be lazy about it all, take their insulin and not change one single thing about their lives, even after SEEING that when they DO lost the weight, cut out the booze and carbs and white sugar and otherwise behave themselves, their blood sugar is just fine.
I understand, but it is very hard to do. I think the disease also makes people crave the very thing that makes them sicker - carbs.
I have type 2 in my family as well. It’s a horrible disease.
Stay well, fellow Freeper. :-)
Vitamin d3 plays a big role as well. You are probably outside more than your family due to your job.
This whole article seems like nonsense to me. It’s well established that Type 1 diabetes is an autoimmune disease that destroys the pancreatic islets of langerhan, and that Type 2 diabetes is caused by cellular desensitization to insulin due to massive overproduction of insulin due to massive and continuous ingestion of sugary and carby foods that repeatedly spike blood sugar, with said desensitization causing the pancreatic islets of langerhan to make enormous amounts of insulin to compensate, with eventual exhaustion of the islets of langerhan.
No one in my immediate family had diabetes II, except me.
No one in my spouse’s immediate family, mother,father, siblings, grandparents, had the disease, but he contracted it.I would like to know the answer as to why, hopefully in my lifetime.
I understood that generally type II diabetes ran more in families who were short, especially short legged, as if maybe the legs being one of our largest body types had something to do with the digestion or lack of digestion of carbs.
No one in my family has it, being a bit tall, but my very tall son who has played some college sports said that he was told by various nutritional counselors that if one eats enough sugar it will coat the red blood cells and eventually cause type II.
Maybe that is true, as I have several friends from short families and they tell me it runs in the family. They try to watch their carbs. I have a tall friend who has eaten a lot of carbs, sugar junky, and has type II.
It is a terrible disease and it would be great for so many if some cure were found.
It doesn't seem to square with the “epidemic” of type 2 diabetes in this country that seems to correspond closely with the “epidemic” of obesity. Of course our “epidemic” of obesity seems to correspond with the increased popularity of super-sized fast food, candy and corn syrup based soft drinks.
Around the time that I turned 50 I realized that my gastric system was starting to rebel against the staples in my diet such as 64oz Double Big Gulps, jumbo sized Big Bite Hot-dogs, potato chips and large quantities of candy bars. When I was younger I could gorge on these types of culinary delights day after day with no apparent ill effects. But around the time I turned 50 all those great highly refined food products, the pinnacle of modern industrial food preparation began giving me abdominal pain and diarrhea.
I was forced to change my dietary habits, even give up my normal half gallon of milk every day which had been used to wash down all those candy bars and cookies. My gastric system forced me to start eating less candy, grease filled hot-dogs, hamburgers and sandwiches. I had to stop drinking half gallon sized big gulps filled with caffeinated corn syrup based soft drinks.
It is crazy, but I find that I have lost weight, am sleeping better, feeling better and have more energy. Who da thunk it?
There was a company called Amylin Pharmaceuticals that was bought out a couple of years ago. They produced drugs for diabetes.
I am the only one in my extended family that has it. A nurse told me that an 87 yr. old can get Type I. I think it was the Cherry Coke that did me in.
“No one in my immediate family had diabetes II, except me.
No one in my spouses immediate family, mother,father, siblings, grandparents, had the disease, but he contracted it.I would like to know the answer as to why, hopefully in my lifetime.”
Either one of you take statins for an extended period...I know someone with the same lack-of-family background that blames statins for the condition.
I think it is possible that type 2 could be an autoimmune disease, too. Time will tell.