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Diet/lifestyle program reverses biological age: A female case series (8 wk diet reversed 4.6 years of aging)
Medical Xpress / Impact Journals LLC / Aging ^ | April 3, 2023 | Kara N. Fitzgerald et al

Posted on 04/03/2023 7:27:39 PM PDT by ConservativeMind

click here to read article


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To: ConservativeMind

Really excellent journal article.

Thank you for sharing.

Everytime I read about methylation, I think of the research done by Randy Jirtle at Duke University with agouti mice that are predisposed to cancer, obesity and diabetes. With methylation, he removed the expression of the genetic predisposition in the offspring. Bruce Lipton wrote about this in “Biology of Belief.”

https://www.nature.com/scitable/topicpage/obesity-epigenetics-and-gene-regulation-927/


41 posted on 04/04/2023 3:25:25 AM PDT by tired&retired (Blessings )
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To: ConservativeMind

42 posted on 04/04/2023 3:29:28 AM PDT by tnlibertarian
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To: ConservativeMind

This subject fascinates me.

It appears that a childhood trauma and the related stress somehow removes the natural methylation protection. I have observed the effect of inter-generational trauma on inherited obesity.

In one very obese woman, I found severe early childhood trauma. The result in testing was more profound than I had ever observed.

We removed the extreme emotion attached to the trauma memories and several months later the woman contacted me that she had lost over 50 lbs without trying.

Decreased methylation due to the stress of the trauma appeared to be the root cause of the obesity.

B-vitamins are very important in methylation.

Still figuring out the details of this puzzle.

Your posted medical articles are a blessing in this process.

Thank You.


43 posted on 04/04/2023 3:36:32 AM PDT by tired&retired (Blessings )
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To: ConservativeMind

Just stumbled onto this very interesting article:

DNA methylation in the pathogenesis of polycystic ovary syndrome

https://rep.bioscientifica.com/configurable/content/journals$002frep$002f158$002f1$002fREP-18-0449.xml?t:ac=journals%24002frep%24002f158%24002f1%24002fREP-18-0449.xml


44 posted on 04/04/2023 3:43:50 AM PDT by tired&retired (Blessings )
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To: tired&retired

From the article:

“Remarkably, exposure to elevated androgens early in life, such as in women with congenital adrenal hyperplasia and prenatally androgenized animals, correlates with a decline in the negative feedback effect of estradiol and progesterone in the GnRH-mediated release of LH, which is a typical characteristic in women with PCOS (Blank et al. 2006).

A study recently proposed that prenatal exposure to androgens results in aberrant fetal programming in GnRH neurons that impairs their response to the steroid hormones negative feedback in mice (Silva et al. 2018).”


45 posted on 04/04/2023 3:48:53 AM PDT by tired&retired (Blessings )
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To: ConservativeMind

I’m good where I’m at.

If I could do it all over again, I wouldn’t.

If I could start today at any age I wanted I’d pick my current age.

If I could take a drug to make me live forever I wouldn’t.

Joint pain free would be nice but otherwise I’m good.


46 posted on 04/04/2023 4:46:46 AM PDT by maddog55 (The only thing systemic in America is the left's hatred of it!)
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To: reed13k

BFL


47 posted on 04/04/2023 5:52:52 AM PDT by reed13k (For evil to triumph it is only necessary that good men do nothing)
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To: ConservativeMind

How to Support Methylation + Why It’s Important for Your Health
By Jillian Levy, CHHC
May 4, 2022
(Dr Axe website)
https://draxe.com/health/methylation/


48 posted on 04/04/2023 6:10:50 AM PDT by dennisw
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To: Jamestown1630

My hubby would be on your list too. He is a meat and potatoes guy. He’s 73, and recovering from Covid, colon cancer removal, and chemo. Fatigue is his biggest battle.

He would never do smoothies, any green vegetables except green beans and peas. They kept asking during chemo, any nausea? In 53, nearly 54 yrs married, I’ve known him to be nauseous maybe once.


49 posted on 04/04/2023 6:25:29 AM PDT by grame (May you know more of the love of God Almighty this day!)
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To: cherry

I guess the longer we live, the longer we have to do something good in the world.

Some things may be up to us, but everyone’s time comes. I have to assume that God has His reasons for someone living to be 105, and someone else dying much younger.


50 posted on 04/04/2023 12:33:24 PM PDT by Jamestown1630 ("A Republic, if you can keep it.")
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To: Jamestown1630

Some things may be up to us, but everyone’s time comes. I have to assume that God has His reasons for someone living to be 105, and someone else dying much younger.

- - - - - - -

1000 million years from now, maybe that will seem like an irrelevant difference.


51 posted on 04/04/2023 12:55:48 PM PDT by TTFX
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To: TTFX

Do you suppose the Earth will be here that far in the future?

If humanity survives that long, I suspect our far descendants will probably be living on other planets by then and won’t even remember Earth...especially if they had originally arrived there as bits of meteor-borne ‘flotsam’.


52 posted on 04/04/2023 1:48:43 PM PDT by Jamestown1630 ("A Republic, if you can keep it.")
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To: Jamestown1630

Maybe not, but things might exist in some form.


53 posted on 04/04/2023 2:21:13 PM PDT by TTFX
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To: TTFX

Ideas and Ideals live forever. They’re made of Mind, not of Flesh.

Let’s hope that wherever/however Earth Humanity winds up, our best ideas and highest idealism still live.


54 posted on 04/04/2023 4:54:44 PM PDT by Jamestown1630 ("A Republic, if you can keep it.")
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To: logi_cal869

Well, let me know when your book gets published


55 posted on 04/04/2023 11:49:13 PM PDT by ConjunctionJunction (Vim vi repellere licet)
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To: ConservativeMind

Ping for later.


56 posted on 04/07/2023 8:45:28 PM PDT by BushCountry (A properly cast vote (1 day voting) can save you $3.00 a gallon.)
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