Perhaps in my lifetime they'll move the Holy See to Brazzaville or Seoul, on the grounds that it's pointless to have the Catholic Church be headquartered in a place where there aren't any Catholics.
Actually, there has been an uptick in Catholic practice in Italy during John Paul's pontificate. According to Cardinal Ruini, the level of religious observance in Italy approaches that of the United States. Not great, but better than much of the rest of Europe. An awful lot of Italians went to pay their respects to the Pope, you know.