Free Republic
Browse · Search
News/Activism
Topics · Post Article

Skip to comments.

Treatments: Artery Cleanup Misses Its Mark
NY Times ^ | April 26, 2005 | ERIC NAGOURNEY

Posted on 04/29/2005 5:37:26 PM PDT by neverdem

VITAL SIGNS

Treatments: Artery Cleanup Misses Its Mark

A common bacterium has been found in the plaque that builds up in the coronary arteries, and infection with it may be linked to cardiovascular illness.

With that in mind, researchers suspected that giving heart patients an antibiotic to knock out the bacterium might reduce their risk of more cardiac problems.

But, the drugs do not seem to help at all, two new studies in The New England Journal of Medicine report.

"The testing of these agents for the treatment of advanced coronary heart disease appears to be at the end of the road," concluded an editorial in the journal by Dr. Jeffrey L. Anderson of the University of Utah School of Medicine.

Still, infection's role in heart disease remains very much an issue.

In one study, about 4,000 men and women were given either a once-a-week antibiotic or a placebo for a year, and then were followed up for an average of almost four years. All the participants had stable coronary artery disease after having various problems or procedures.

The study found that those who had been given the drug suffered the same number of new heart problems as those who did not.

The second study also looked at about 4,000 patients, but used a different drug for two weeks and then for 10 days a month over about two years. It, too, found no difference between those people given the drug and those given a placebo.

Dr. J. Thomas Grayston of the University of Washington and Dr. Christopher P. Cannon of Harvard led the studies.


TOPICS: Culture/Society; Extended News; Technical
KEYWORDS: health; heart; medicine; nanobacteria
Navigation: use the links below to view more comments.
first 1-2021-31 next last
Here are the abstracts.

Azithromycin for the Secondary Prevention of Coronary Events

Antibiotic Treatment of Chlamydia pneumoniae after Acute Coronary Syndrome

1 posted on 04/29/2005 5:37:27 PM PDT by neverdem
[ Post Reply | Private Reply | View Replies]

To: El Gato; JudyB1938; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; ..

FReepmail me if you want on or off my health and science ping list.


2 posted on 04/29/2005 5:38:40 PM PDT by neverdem (May you be in heaven a half hour before the devil knows that you're dead.)
[ Post Reply | Private Reply | To 1 | View Replies]

Comment #3 Removed by Moderator

Comment #4 Removed by Moderator

To: theheebrewhammer

Thanks for the link.


5 posted on 04/29/2005 5:56:48 PM PDT by neverdem (May you be in heaven a half hour before the devil knows that you're dead.)
[ Post Reply | Private Reply | To 3 | View Replies]

To: theheebrewhammer

nanobacteria freak me out.


6 posted on 04/29/2005 6:00:19 PM PDT by bitt ("There are troubling signs Bush doesn't care about winning a third term." (JH2))
[ Post Reply | Private Reply | To 4 | View Replies]

To: neverdem
"...were given either a once-a-week antibiotic or a placebo..."

Well.....maybe they should give the antibiotic MORE than ONCE a week???

7 posted on 04/29/2005 6:57:28 PM PDT by goodnesswins (Our military......the world's HEROES!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: goodnesswins

Great link on nanobacteria - the calcium shells would seem to require more than antibiotics more than once a week.

I was always intrigued by bacteria link between ulcers and plaque - this seems to make sense.


8 posted on 04/29/2005 7:06:28 PM PDT by spanalot
[ Post Reply | Private Reply | To 7 | View Replies]

To: goodnesswins

And maybe they should give it prospectively to people who do not already have plaque build-up.


9 posted on 04/29/2005 7:08:03 PM PDT by From many - one.
[ Post Reply | Private Reply | To 7 | View Replies]

To: theheebrewhammer; bitt; All
I've heard about nanobacteria before, but not much. PubMed had 59 citations. The following link free full text articles.

Association Between Nanobacteria and Periodontal Disease

Attempted Isolation of Nanobacterium sp. Microorganisms from Upper Urinary Tract Stones

Inhibition of Nanobacteria by Antimicrobial Drugs as Measured by a Modified Microdilution Method

An alternative interpretation of nanobacteria-induced biomineralization

Nanobacteria and associated ‘elementary bodies’ in human disease and cancer

Nanobacteria: An alternative mechanism for pathogenic intra- and extracellular calcification and stone formation

10 posted on 04/29/2005 7:22:55 PM PDT by neverdem (May you be in heaven a half hour before the devil knows that you're dead.)
[ Post Reply | Private Reply | To 4 | View Replies]

To: goodnesswins
Well.....maybe they should give the antibiotic MORE than ONCE a week???

I wonder how many folks became ill with yeast or some other fungus, especially in the other study.

11 posted on 04/29/2005 7:32:43 PM PDT by neverdem (May you be in heaven a half hour before the devil knows that you're dead.)
[ Post Reply | Private Reply | To 7 | View Replies]

To: From many - one.; spanalot

Well....I'm taking minocycline 2x a day.....long term.....I'll let you know if it works....LOL (THIS is kind of interesting to me, as I've got some kind of inflammation problem, which MAY be Lyme Disease....the Rheum Docs want it to be Rheumatoid Arthritis....but, I'm fairly confident it is NOT.....I'm still trying to get it figured out.)


12 posted on 04/29/2005 7:33:56 PM PDT by goodnesswins (Our military......the world's HEROES!)
[ Post Reply | Private Reply | To 9 | View Replies]

To: neverdem

See Post 12.....I haven't had a problem YET....and it's been about 7 months.....


13 posted on 04/29/2005 7:35:33 PM PDT by goodnesswins (Our military......the world's HEROES!)
[ Post Reply | Private Reply | To 11 | View Replies]

To: neverdem

See Post 12.....I haven't had a problem YET....and it's been about 7 months.....


14 posted on 04/29/2005 7:35:39 PM PDT by goodnesswins (Our military......the world's HEROES!)
[ Post Reply | Private Reply | To 11 | View Replies]

To: goodnesswins

Elevated ANA but negative RA?


15 posted on 04/29/2005 7:38:55 PM PDT by Judith Anne (Thank you St. Jude for favors granted.)
[ Post Reply | Private Reply | To 12 | View Replies]

To: Judith Anne

NO....don't think my ANA was even elevated much....but, I'd have to check for sure. How ya doin?


16 posted on 04/29/2005 7:43:38 PM PDT by goodnesswins (Our military......the world's HEROES!)
[ Post Reply | Private Reply | To 15 | View Replies]

To: spanalot
Much more on the topic of germs, heart disease and antibiotics here.
17 posted on 04/29/2005 7:44:16 PM PDT by The Radical Capitalist
[ Post Reply | Private Reply | To 8 | View Replies]

To: Judith Anne

NO....don't think my ANA was even elevated much....but, I'd have to check for sure. How ya doin?


18 posted on 04/29/2005 7:45:52 PM PDT by goodnesswins (Our military......the world's HEROES!)
[ Post Reply | Private Reply | To 15 | View Replies]

To: goodnesswins

Sorry for all the double posts....I'm having computer problems....OBVIOUSLY.


19 posted on 04/29/2005 7:48:52 PM PDT by goodnesswins (Our military......the world's HEROES!)
[ Post Reply | Private Reply | To 18 | View Replies]

To: goodnesswins

I started with an elevated ANA and negative RA, and after a year, positive RA.

I'm doing okay. I'm still using high-dose aspirin and staying away from the nightshade family, and taking myrrh capsules, and using 1-2 Ultram 50 per day.

And I'm able to be very active, physically. Occasionally I am REALLY tired for no reason, but other than that, I'm doing okay. My pain level is in the tolerable range. Hand joints swell and subside on a daily basis.


20 posted on 04/29/2005 7:49:30 PM PDT by Judith Anne (Thank you St. Jude for favors granted.)
[ Post Reply | Private Reply | To 18 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-31 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
News/Activism
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson