" "The clustering of regulatory sequences is incredibly interesting," said Kerstin Lindblad-Toh, first author of the Nature paper and co-director of the genome sequencing and analysis program at Broad."
I have been saying for awhile that this a key component in evolution. I think the more critters that get sequenced, the more profound these "non-coding" differences will be. I am looking forward, eagerly.
We had a thread a while back on very conserved areas of the genome. One idea tossed around is that the more vital a particular sequence is, the more likely it is to remain conserved, simply because if it varies (which it may) the consequences are catastrophic, so only the conserved versions survive to participate in the biosphere.