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Woolly mammoth genome comes to life (Jurassic Park, here we come)
EurekAlert! ^ | December 22, 2005 | Staff

Posted on 12/22/2005 9:33:04 PM PST by DaveLoneRanger

Decoding extinct genomes now possible, says geneticist A McMaster University geneticist, in collaboration with genome researchers from Penn State University and the American Museum of Natural History has made history by mapping a portion of the woolly mammoth's genome. The discovery, which has astounded the scientific world, surpasses an earlier study released today by Nature that also concerns the woolly mammoth. Hendrik Poinar, a molecular evolutionary geneticist in the department of anthropology and pathology at McMaster University, says his study involves the vital nuclear DNA within a Mammoth rather than the lesser mitochondria, on which the Nature study is based.

"Mitochondria is so 1980s. It only allows you to look at the maternal side of evolution," says Poinar. "The nuclear DNA we've mapped gives us our first glimpse at both sides of evolution. We can sequence Neanderthals, animals, plants. Basically, if we find a well-preserved specimen, we can sequence its genome."

The discovery occurred when Poinar extracted DNA from a well-preserved Mammoth specimen found in the Siberian permafrost, and sent it to his research colleagues at Penn State, who had just taken possession of the latest technology in genome sequencing. Within hours, his colleagues reported that the machine had sequenced 30 million base pairs, about one percent of the entire Mammoth genome. At this rate, it will take a year to map the entire genome, says Poinar. Funding is currently being sought for the completion of this project.

"We were stunned," says Poinar. "We immediately understood the magnitude of this discovery. Once you successfully sequence a genome, there are a million interesting questions one can begin to address. To acquire the genome of an extinct species is a rare feat. With this level of genetic data we can begin to look at genes to determine what makes a Mammoth a Mammoth. We can finally understand the subtle differences between a Mammoth and its closest living relative, the Indian elephant, but more importantly our discovery means that recreating extinct hybrid animals is theoretically possible."

Woolly mammoths, which have become symbols of the Ice Age, died out 10,000 years ago.

"Naturally there are ethical issues that come with a discovery of this magnitude, and McMaster is already planning the first conference devoted to the ethics of bringing extinct organisms back to life," said Mamdouh Shoukri, vice-president research and international affairs. "We have an obligation as scientists to explore and maintain the responsible use of research."


TOPICS: Culture/Society; Front Page News; Miscellaneous
KEYWORDS: cloning; crevolist; dna; extinction; gene; genetics; genome; godsgravesglyphs; helixmakemineadouble; humangenome; jurassicpark; mammoth; mammoths; mammothtoldme; pleistocenepark; rewilding; rewildingamerica
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To: TheRedSoxWinThePennant
>Wake me up when we they get Velocoraptors



And wake me up when
Loana gets back into
her cave girl swim suit . . .

51 posted on 12/23/2005 2:24:51 PM PST by theFIRMbss
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To: DaveLoneRanger
I want a periodical that is saddle broken!
52 posted on 12/23/2005 2:33:03 PM PST by dalereed
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To: DaveLoneRanger
First of all, thanks for a fascinating post.

"Naturally there are ethical issues that come with a discovery of this magnitude, and McMaster is already planning the first conference devoted to the ethics of bringing extinct organisms back to life," said Mamdouh Shoukri, vice-president research and international affairs. "We have an obligation as scientists to explore and maintain the responsible use of research."

Ethics is pretty much irrelevent in science. If it's possible, somebody, somewhere will do it.

53 posted on 12/23/2005 3:28:48 PM PST by Richard Kimball (Tenure is the enemy of excellence.)
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To: Joe 6-pack
I'm all for bringing them back as an entree...

I've always wondered what the dodo bird tasted like myself.

54 posted on 12/23/2005 6:41:03 PM PST by Reaganwuzthebest
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To: steel_resolve

Toni Basil? Her one song got play for, what, three weeks in December of 1982? What made you flash back to that one-hit-wonder?


55 posted on 12/23/2005 7:17:36 PM PST by SC Swamp Fox (Bush lied, people dyed....their fingers.)
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To: ClearBlueSky

I could live with that!


56 posted on 12/23/2005 7:20:47 PM PST by going hot (Happiness is a momma deuce)
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To: Ol' Dan Tucker

Mmmmnnnnnn! Roast reptile!

Of all the man portable weapon proposals on this thread, yours is by far the best.


57 posted on 12/23/2005 8:32:10 PM PST by GladesGuru (In a society predicated upon Liberty, it is essential to examine principle)
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To: GladesGuru
Mmmmnnnnnn! Roast reptile!

Tastes like chicken!

Of all the man portable weapon proposals on this thread, yours is by far the best.

Thanks. For pure defense in a life-or-death situation involving animals like a T-Rex or a herd of hungry utahraptors, it's hard to beat. If I were on an island inhabited by dinasaurs, I'd feel mighty safe walking around with one strapped to my back.

58 posted on 12/24/2005 1:01:28 AM PST by Ol' Dan Tucker (Karen Ryan reporting...)
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To: Caipirabob
LOL! Yes, after I found it I did a search. Turns out "Land Of The Lost" is available on DVD. I'm going to use netflix and get it for my kids to watch.

I remember (many years into the series) when they had the equivalent of the Darth-Vader-"I-am-your-father" moment on Land of the Lost... and that is, when, contrary to their assumption that Sleestaks had been some reptilian ancestor on earth, that they come to find that Sleestaks were the evolutionary destiny of mankind. LOL! That show was so campy, I couldn't help laughing.

59 posted on 12/28/2005 5:42:23 PM PST by XEHRpa
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To: XEHRpa
I ended up finding the first three seasons on Netflix. Looks like we'll be "revisiting" LOL again soon. You know, I miss shows that had no agenda and we could let children watch without fear.
60 posted on 12/29/2005 1:38:30 AM PST by Caipirabob (Democrats.. Socialists..Commies..Traitors...Who can tell the difference?)
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Just adding this to the GGG catalog, not sending a general distribution.

To all -- please ping me to other topics which are appropriate for the GGG list. Thanks.
Please FREEPMAIL me if you want on or off the
"Gods, Graves, Glyphs" PING list or GGG weekly digest
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61 posted on 05/31/2006 7:13:18 PM PDT by SunkenCiv (https://secure.freerepublic.com/donate/)
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To: DaveLoneRanger

Related:

http://www.freerepublic.com/focus/f-chat/1568683/posts
A Real-Life Jurassic Park


62 posted on 05/31/2006 7:15:00 PM PDT by Calpernia (Breederville.com)
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To: ClearBlueSky

Now that's an idea!


63 posted on 05/31/2006 7:25:29 PM PDT by Trillian
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To: Joe Boucher

She was cremated.


64 posted on 08/14/2006 9:40:39 PM PDT by SunkenCiv (updated my FR profile on Thursday, August 10, 2006. https://secure.freerepublic.com/donate/)
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· join list or digest · view topics · view or post blog · bookmark · post a topic · subscribe ·

 
Gods
Graves
Glyphs
Just updating the GGG info, not sending a general distribution.

To all -- please ping me to other topics which are appropriate for the GGG list.
GGG managers are SunkenCiv, StayAt HomeMother, and Ernest_at_the_Beach
 

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65 posted on 03/05/2010 7:33:10 PM PST by SunkenCiv (Freedom is Priceless.)
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To: DaveLoneRanger
Decoding extinct genomes now possible, says geneticist A McMaster University geneticist, in collaboration with genome researchers from Penn State University...

LOL -and Joe Pa can even tell em' what the thing looked like. Go Lions!

66 posted on 03/05/2010 7:35:44 PM PST by 70times7 (Serving Free Republics' warped and obscure humor needs since 1999!)
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