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The sentence you quoted stated that IDDM was not linked to body weight. Perhaps you wrote a typo?

Yup. Shouldn't post when tired. I missed the "not". (And I read the darn thing three times. Crap.)

I'm going a bit off topic here, but I don't think T2 is always linked to body weight. I know of one T2 (in particular) who was a skinny vegetarian before diagnosis.

I also wonder about the whole "T2 is linked to being fat" theory. About 6 years ago I suddenly gained 30 pounds (in less than a month) and started craving carbs like a fiend. I tried diet and exercise as soon as the scale started shooting up and ended up on a 800-900 cal a day diet with exercise. I gained another 10 pounds in just two weeks. (And, no. I didn't cheat. I wrote down *everything*.) I went to the dr and found out that I had insulin resistance, but was not yet a T2. I was put on Metformin and a low carb diet and, after a year, I was back to normal.

I'm thinking that the carb cravings and the weight gain are not a self-induced situation that results in T2 diabetes, but symptoms of the beginning of the disease.

I digress. Back to the article. My son is a T1 and we will NOT be using the inhaled insulin for a very long time. Shots are really not that big of a deal for this diabetic and I am seriously concerned about the side-effects for the lungs.

NIDDM does have both a genetic and environmental component, so you are correct that it is not solely linked to body weight. However, the genes that predispose to NIDDM (which are multifactorial and so can't be named with 100% certainty, although the genetic component is still undeniable) tend only to be expressed when an individual is overweight and with high circulating lipids, leading to metabolic syndrome.

Now that all being said, if the genetic tendency to develop insulin resistance is especially strong for an individual, that person can develop NIDDM without being overweight. However, if that person were overweight, they would invariably develop the insulin resistance at a younger age.

At least, that's what my biochemistry professor told me when I was an MS1.

..side-effect damage to the lungs.

Don't worry, when that occurs, they will market a drug for that.

Probably injectable.

"Cure Cancer?, Are you kidding, they're still mad over the money they lost curing polio!"

- Chris Rock -