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The Red-Hot Power Of Chillies Can Kill Cancer
The Telegraph (UK) ^ | 3-16-2006 | Roger Highfield

Posted on 03/16/2006 5:05:15 PM PST by blam

The red-hot power of chillies can kill cancer

By Roger Highfield, Science Editor
(Filed: 16/03/2006)

The substance in chillies that causes the tongue to burn also drives prostate cancer cells to kill themselves, according to research that could pave the way for new treatments.

The pepper component capsaicin makes the cells undergo programmed cell death or apoptosis, says a study published in the journal Cancer Research.

High intake of hot chillis has been linked to stomach cancer

Tests found that it induced approximately 80 per cent of cancer cells growing in mice to follow the molecular pathways leading to apoptosis.

Prostate cancer tumours treated with capsaicin were about one-fifth the size of tumours in non-treated mice, said a team from the Cedars-Sinai Medical Centre, Los Angeles, in collaboration with colleagues from the University of California, Los Angeles.

Every year, 10,000 men die and more than 30,000 are diagnosed with prostate cancer in the UK.

"Capsaicin had a profound anti-proliferative effect on human prostate cancer cells in culture," said Dr Sören Lehmann, team member.

He estimated that the dose of pepper extract fed to the mice was equivalent to giving 400 milligrams of capsaicin three times a week to a 200-pound man, roughly equivalent to between three and eight fresh habañera peppers.

Britain's Prostate Cancer Charity welcomed the study, but advised men not to eat more hot chillis.

Head of Policy and Research, Chris Hiley, said: "Eventually, it may be possible to extract the capsaicin and make it available as a drug treatment. In the meantime we caution men with prostate cancer in the UK against upping their weekly intake of the hottest known chillies. High intake of hot chillies has been linked with stomach cancers in the populations of India and Mexico."


TOPICS: News/Current Events
KEYWORDS: apoptosis; can; cancer; capsaicin; cedarssinai; chili; chilipepper; chillies; hot; india; kill; mexico; power; prostatecancer; red; stomachcancer; ucla

1 posted on 03/16/2006 5:05:17 PM PST by blam
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To: blam
Natures supository

Image hosting by TinyPic
2 posted on 03/16/2006 5:08:10 PM PST by cripplecreek (Never a minigun handy when you need one.)
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To: blam

Hmmmmm...take too many, get stomach cancer. Don't take enough, get ass cancer.

Dilemas, dilemas...(or is that "dilenemas"?)


3 posted on 03/16/2006 5:09:06 PM PST by OCCASparky (Steely-Eyed Killer of the Deep)
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To: blam
Hey great article. I don't eat the quantity of hot peppers as the Indians or Mexicans but its definitely more than the average American.

I make a good Chile Verde, :)

Wolf
4 posted on 03/16/2006 5:09:14 PM PST by RunningWolf (Vet US Army Air Cav 1975)
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To: blam

Even cancer cells can't resist. Those peppers just leave a burned out flaming path upon exiting. Aye carumba.


5 posted on 03/16/2006 5:09:24 PM PST by King Moonracer
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To: RunningWolf

Care to share the recipe?


6 posted on 03/16/2006 5:11:43 PM PST by OKSooner
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To: blam

Interesting study, but it didn't help my dad. From the time I was a little girl, I can remember him eating hot peppers like they were candy; we always had large jars of hot peppers in the refrigerator. Prostate cancer did him in 15 years ago.


7 posted on 03/16/2006 5:12:21 PM PST by tgslTakoma
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To: cripplecreek

Also known as Pric Kee Nu or (Rat Sh!t Chili).


8 posted on 03/16/2006 5:14:08 PM PST by JimSEA (America cannot have an exit strategy from the world.)
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To: OCCASparky; neverdem
Hmmmmm...take too many, get stomach cancer. Don't take enough, get ass cancer.

Maybe somebody should figure out how to make a capsule of capsaicin that doesn't completely dissolve until it gets into the small intestine AFTER it exits the stomach?

9 posted on 03/16/2006 5:17:45 PM PST by FreeKeys ("Marxism is dying globally, but it's alive and kicking at America's universities." -- Ben Shapiro)
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To: FreeKeys
Maybe somebody should figure out how to make a capsule of capsaicin that doesn't completely dissolve until it gets into the small intestine AFTER it exits the stomach?

Make the shell out of corn maybe?

10 posted on 03/16/2006 5:22:14 PM PST by aomagrat ("Now having seen muslim mercy, I would rather worship cobras." - New Martyr Anathasios)
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To: blam

Wheres Flea?


11 posted on 03/16/2006 5:24:00 PM PST by skaterboy
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To: OKSooner
No problem, I am not able to access it at the moment though.
12 posted on 03/16/2006 5:30:07 PM PST by RunningWolf (Vet US Army Air Cav 1975)
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To: OKSooner

Mail me and I'll send ya mine--chili verde, made with pork, of course.

I call it "terrorist repellent".


13 posted on 03/16/2006 5:31:01 PM PST by OCCASparky (Steely-Eyed Killer of the Deep)
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To: FreeKeys

Or peanut shells?

C'mon, ice cream!!!!


14 posted on 03/16/2006 5:31:42 PM PST by OCCASparky (Steely-Eyed Killer of the Deep)
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To: blam
High intake of hot chillies has been linked with stomach cancers in the populations of India and Mexico.

Nothing to do with the unsanitary conditions and lifestyles in those places, of course. Chow down on another habanero and live forever, gents !!!!

15 posted on 03/16/2006 5:31:54 PM PST by AbeKrieger (The needs of the many outweigh the needs of the few. Or the one.)
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To: aomagrat
Make the shell out of corn maybe?

LOL!

16 posted on 03/16/2006 5:34:14 PM PST by Semper911 ("We can stand here like the French, or we can do something about it." -Marge Simpson)
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To: King Moonracer
Those peppers just leave a burned out flaming path upon exiting.

They never have that effect on me. Must be because I'm an insensitive a-hole.

17 posted on 03/16/2006 5:34:59 PM PST by Lovely-Day-For-A-Guinness (Eenie meanie, chili beanie, the spirits are about to speak....)
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To: blam

Hmmmm, what to do with that batch of jalapeno potato salad I just made?
Answer: I'll risk it. It came out gooood.


18 posted on 03/16/2006 6:13:32 PM PST by dynachrome ("Where am I? Where am I going? Why am I in a handbasket?")
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To: blam

So I guess prostate cancer is rare in Mexico?


19 posted on 03/16/2006 6:19:56 PM PST by csmusaret (Urban Sprawl is an oxymoron)
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To: RunningWolf

Cool. Just send it via freepmail and I'll give it a try.


20 posted on 03/16/2006 6:35:01 PM PST by OKSooner
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To: blam; All

Also see: http://www.freerepublic.com/focus/f-news/1596929/posts


21 posted on 03/16/2006 7:16:07 PM PST by FreeKeys ("Egalitarianism is worse than stupid, it's immoral." -- P.J. O'Rourke)
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To: blam
I used to be able to eat grilled jalapenos and habenero salsas ... stuff that would make your ears sweat.

I loved it! Eating super-spicey food can give you the same endorphins "buzz" runners get.

Now I have acid reflux. Can't eat the stuff any more. I sure miss it.

22 posted on 03/16/2006 7:51:14 PM PST by manwiththehands (Islam is as Islam does.)
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To: blam

They cause cancer? Who knew?

23 posted on 03/16/2006 8:00:05 PM PST by WestVirginiaRebel (A fool and his money are soon parted. Democrats love fools.)
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To: blam

I thought a chillie was the opposite of a hottie.


24 posted on 03/16/2006 11:22:02 PM PST by Erasmus (Eat beef. Someone has to control the cow population!)
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