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High-protein diet reduces appetite
News@nature.com ^ | 5 September 2006 | Michael Hopkin

Posted on 09/05/2006 12:57:57 PM PDT by Mount Athos

Eating a high-protein diet can boost the release of a hunger-suppressing hormone, according to new study on mice. The research suggests that a diet rich in protein may be a good way to lose weight and keep it off.

Mice fed a protein-heavy diet produced higher levels of an appetite-regulating protein called peptide YY (PYY), which has been linked to reduced appetite in human studies. What's more, the high-protein mice put on less fat than mice on a low-protein regime.

The discovery boosts the theory that eating more protein might help to reduce appetite and lead to sustained weight loss, says Rachel Batterham of University College London, who led the research, published in the journal Cell Metabolism1. "All the evidence suggests that it will be beneficial," she says.

The discovery may also shed light on how the notorious Atkins diet, which ditches carbohydrates in favour of protein and saturated fats, might work. Studies have shown that people on this diet can loose weight, though it is unclear why. Batterham thinks she may have the answer: "People on the Atkins diet don't feel as hungry — that's how it works."

But, she cautions, that doesn't mean the Atkins diet is a good idea: "No medical person is going to tell you to have all that saturated fat in your diet and no carbohydrates." In its early stages, the regime causes a condition called ketosis, in which the liver, deprived of glycogen from carbohydrates, switches to its starvation mode and begins to metabolize fatty compounds. "The problem is that it makes you feel terrible," Batterham says.

She now plans to organize a long-term study of the effects of a high-protein diet in humans, which might feature foods such as lean meat, soy, tofu and egg.

Batterham undertook this study in part to pin down the link between PYY and appetite. Her team first showed that the hormone reduces appetite in humans in a Nature paper2 in 2002, but other researchers said they could not replicate the effect. So her team turned to mice to investigate it in more depth.

In the new study, as well as showing that mice fed lots of protein put on less weight, Batterham and her colleagues also genetically engineered mice to lack functioning PYY. These mice ate more and became fatter, even on a high-protein regime. When these mice were dosed with replacement PYY, they stopped gorging. This proves, says Batterham, that a lack of PYY is directly linked to overeating.

That might explain why people are growing ever more obese. Since the agricultural revolution, the amount of protein in the average diet has been declining, in favour of carbohydrates from plant crops such as rice and maize. The typical Western diet contains only 16% protein, whereas a prehistoric hunter-gatherer would have consumed twice as much, Batterham claims.

High-protein eating habits such as the 'caveman diet', which can contain up to 35% protein, might therefore be based on some sound principles, Batterham suggests. The PYY system, she points out, has been around for millions of years, and is found in animals ranging from humans right through to primitive fish called lampreys.

Batterham stresses that such diets will still need to be investigated to see if they carry risks of high cholesterol, kidney damage or other problems. "Prehistoric hunter-gatherers did not routinely live to be 80 years old," she points out.


TOPICS: Culture/Society; News/Current Events
KEYWORDS: atkins; atkinsdiet; carboyhdrates; duhatkinsknewthis; nutrition; proteinpower; saturatedfat
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1 posted on 09/05/2006 12:57:57 PM PDT by Mount Athos
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To: Mount Athos

yeah, a high protein diet will reduce your appetite as you deal with the pain fromt he Kidney stone you get with it. Also isn't good for your kidneys.


2 posted on 09/05/2006 1:00:36 PM PDT by MAD-AS-HELL (Put a mirror to the face of the republican party and all you'll see is a Donkey.)
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To: Mount Athos

The over-processed, white bread diet that Americans eat is the primary cause of obesity. That coupled with a lack of exercise. High protien diets are not rocket surgery and can produce marked weight loss.


3 posted on 09/05/2006 1:01:00 PM PDT by shankbear
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To: Mount Athos
People on the Atkins diet don't feel as hungry...

That's how it works.

After a week of eating nothing but cheese and meat sauteed in oil, you really don't feel like eating much more cheese and meat sauteed in oil.

4 posted on 09/05/2006 1:01:37 PM PDT by dead (I've got my eye out for Mullah Omar.)
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To: shankbear

In all things moderation. You need not go from one extreme to the other, simply cut back some processed carbs in favor of higher protein will have dramatic results as well without the health risks of an extremely high protein diet.


5 posted on 09/05/2006 1:02:45 PM PDT by dfwgator
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To: Mount Athos
I did Atkins for some time.Atkins is a high protein,low just-about-everything-else diet.I was amazed how easily I was able to avoid various kinds of junk food as well as how easy it was to avoid late night snacking.

Also,while on Atkins,I *never* felt hungry and with the diet,combined with moderate exercise,the pounds (about 30 of them) just melted off of me.

6 posted on 09/05/2006 1:04:33 PM PDT by Gay State Conservative ("An empty limousine pulled up and Hillary Clinton got out")
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To: Mount Athos
If you go the high-protein route, you definately have to drink a lot, and have no history of kidney problems.

Also, periodically, you should do a carb re-feed. That, or you'll sort of go out of your mind.

But it's true --protein will quash the munchies more effectively than fat.

I went from 260 pounds to 201, so far. I also did lot of cardio, of course...

7 posted on 09/05/2006 1:04:37 PM PDT by gaijin
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To: Mount Athos

Staying busy also suppresses the appetite. I honestly believe there is a mechanism in your body that activates an eating impulse when one is idle.

Beyond that, keeping away from prepackaged foods, sodas, and going easy on sweets should take care of most weight problems.


8 posted on 09/05/2006 1:08:14 PM PDT by Sam Cree (Don't mix alcopops and ufo's)
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To: MAD-AS-HELL

That's why South Beach is a good diet. It's high protein and low carb, but not as severe as Atkins. It doesn't stress the kidneys and doesn't put you in ketosis. And it counsels against "bad" fats. But it does work.


9 posted on 09/05/2006 1:08:38 PM PDT by colorado tanker
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To: gaijin
If you go the high-protein route, you definately have to drink a lot, and have no history of kidney problems.

What's the reference to Kidney problems all about?

10 posted on 09/05/2006 1:10:01 PM PDT by frogjerk (REUTERS: We give smoke and mirrors a bad name)
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To: Sam Cree

Why can't I eat what I want but supplement it with a tasty chewable pill providing the magical "appetite reducing" hormone that protein diets are supposed to stimulate?


11 posted on 09/05/2006 1:10:46 PM PDT by neoken
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To: Mount Athos

12 posted on 09/05/2006 1:11:37 PM PDT by Cobra64 (All we get are lame ideas from Republicans and lame criticism from dems about those lame ideas.)
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To: neoken
Why not take Acomplia when it comes out? AKA Rimonabant.

And some cardio.

13 posted on 09/05/2006 1:12:42 PM PDT by gaijin
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To: dfwgator
In all things moderation. You need not go from one extreme to the other, simply cut back some processed carbs in favor of higher protein will have dramatic results as well without the health risks of an extremely high protein diet.

Well said. A good place to start would be to use some kind of beans in place of potatoes as a side item.
14 posted on 09/05/2006 1:13:17 PM PDT by JamesP81 ("Never let your schooling interfere with your education" --Mark Twain)
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To: Mount Athos
She now plans to organize a long-term study of the effects of a high-protein diet in humans, which might feature foods such as lean meat, soy, tofu and egg.

Unfermented soy products are much worse for you than saturated fat.

Soy Alert

The Ploy of Soy

Soy Online Service (S.O.S.)

15 posted on 09/05/2006 1:15:45 PM PDT by Tamar1973 (Don't argue with an idiot; people watching may not be able to tell the difference.)
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To: JamesP81

"A good place to start would be to use some kind of beans in place of potatoes as a side item."

I tried that. My wife put the kibosh on it, though. I [toot] can't imagine why.


16 posted on 09/05/2006 1:17:29 PM PDT by MineralMan (Non-evangelical Atheist)
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To: Tamar1973

I've heard that too. I dislike tofu anyway.
I use soy sauce though


17 posted on 09/05/2006 1:17:39 PM PDT by Mount Athos
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To: Tamar1973

Brought to you by the meat council?


18 posted on 09/05/2006 1:18:06 PM PDT by SlowBoat407 (I've had it with these &%#@* jihadis on these &%#@* planes!)
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To: Mount Athos
Cheap, simple, and no crazy promises:

AllTheWhey.com

Whey protein powder direct, without exotic stuff and sky-high prices.

(I am not a salesman or owner, just a happy customer)

19 posted on 09/05/2006 1:18:22 PM PDT by gaijin
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To: Gay State Conservative
Ok...here's my husband's (Atkins x 3 years) favorite recipe...

Low Carb Brownie

Sift together:

4 T ground flaxseed meal
1 T cocoa powder (unsweetened)
1 T bulk Splenda
1/4 tsp baking soda

Add:

1 egg
1 T Sugar-free vanilla Davinci Syrup (or water)
2 T melted Butter (or canola oil...if you're doing South Beach).

Mix together till well blended. Pour into a small dish sprayed with Pam. Nuke for about a minute and a half. Turn it out onto a plate and eat!

My husband loves these brownies! Sometimes I substitute one of the tablespoons of flaxseed meal with pecan meal, it makes it richer. This make about two servings. He spreads splenda-sweetened cream cheese on his. I think the whole thing only has about the same amount of carbs in a packet of sugar.
20 posted on 09/05/2006 1:19:25 PM PDT by 2Jedismom (Expect me when you see me!)
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To: Cobra64

LOL that's great. I stole the graphic for my homepage.


21 posted on 09/05/2006 1:19:42 PM PDT by Zuben Elgenubi
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To: Mount Athos
I use soy sauce though.

Which is fine b/c it's fermented and a condiment, not a "meat substitute." I eat miso and use soy sauce myself.

22 posted on 09/05/2006 1:19:47 PM PDT by Tamar1973 (Don't argue with an idiot; people watching may not be able to tell the difference.)
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To: MineralMan
My wife put the kibosh on it, though.

I love kibosh!! It has to be the dark stuff, though. The lighter kibosh just doesn't have the same kick.

If you can find it in your area, try the kibosh with garlic.

23 posted on 09/05/2006 1:20:34 PM PDT by SlowBoat407 (I've had it with these &%#@* jihadis on these &%#@* planes!)
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To: Zuben Elgenubi

See the next one of the Code Pink Murtha Babe.


24 posted on 09/05/2006 1:21:28 PM PDT by Cobra64 (All we get are lame ideas from Republicans and lame criticism from dems about those lame ideas.)
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To: Mount Athos

Thing is, a lot of protein sources are loaded with artery blocking stuff. It is improbable that high-protein dieters are living on tofu and beans.


25 posted on 09/05/2006 1:21:28 PM PDT by Jedi Master Pikachu ( Microevolution is real; Macroevolution is not real.)
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To: shankbear
The over-processed, white bread diet that Americans eat is the primary cause of obesity.

A close second is the copious use of corn syrup and high fructose corn syrup in just about everything. That hidden sugar and calories could blow just about any good diet, whether it's Atkins, South Beach, etc.

26 posted on 09/05/2006 1:21:44 PM PDT by Tamar1973 (Don't argue with an idiot; people watching may not be able to tell the difference.)
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To: gaijin

"you definately have to drink a lot"

And if you drink a lot of cold water, your body burns up calories warming it up in your stomach.


27 posted on 09/05/2006 1:22:08 PM PDT by Busywhiskers (Delenda est Hezbollah)
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To: Gay State Conservative
Also,while on Atkins,I *never* felt hungry and with the diet,combined with moderate exercise,the pounds (about 30 of them) just melted off of me.

I lost 25 lbs on it myself.

28 posted on 09/05/2006 1:22:30 PM PDT by Tamar1973 (Don't argue with an idiot; people watching may not be able to tell the difference.)
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To: Zuben Elgenubi
This one's fun too for the incessant diet and soap opera threads.


29 posted on 09/05/2006 1:23:55 PM PDT by Cobra64 (All we get are lame ideas from Republicans and lame criticism from dems about those lame ideas.)
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To: Mount Athos
She now plans to organize a long-term study of the effects of a high-protein diet in humans, which might feature foods such as lean meat, soy, tofu and egg.

Uh, soy and tofu are the same protein.

I would think she meant "dairy".

30 posted on 09/05/2006 1:24:44 PM PDT by ConservativeMind
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To: Tamar1973

My husband lost 45 pounds. His cholesterol runs in the 170s.

We do focus on the good fats when we can, but don't shy away from things like butter or cream or eggs.

One thing we never NEVER use is Crisco or margarine.


31 posted on 09/05/2006 1:25:27 PM PDT by 2Jedismom (Expect me when you see me!)
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To: Mount Athos

This also has the same effect.

32 posted on 09/05/2006 1:25:33 PM PDT by dfwgator
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To: Sam Cree

I believe that it's all about calories and exercise. You can eat 1200 calories of cheeze-its every day for a week and you will lose weight.


33 posted on 09/05/2006 1:25:37 PM PDT by Fawn (http://www.jokaroo.com/funnyvideos/toilet_obsession.html)
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To: Mount Athos
But...But...the loonie left despises the Atkins Diet!!!! They have the holy, venerated South Beach Diet. Praise God. Hallelujah!
34 posted on 09/05/2006 1:26:12 PM PDT by 100-Fold_Return (III John 2)
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To: SlowBoat407
Brought to you by the meat council?

No. I don't eat meat all the time, as a matter of fact, wheat gluten makes a pretty good meat substitute, IMO. There's also a new product out called Quorn, which is made from a mushroom which also works pretty well.

I just think using unfermented soy products of any kind is poisonous to your body, based on the studies out there.

35 posted on 09/05/2006 1:26:13 PM PDT by Tamar1973 (Don't argue with an idiot; people watching may not be able to tell the difference.)
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To: SlowBoat407

Jeez----Kibosh....flaxseed.....I've never heard of these.


36 posted on 09/05/2006 1:28:07 PM PDT by Fawn (http://www.jokaroo.com/funnyvideos/toilet_obsession.html)
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To: Tamar1973

SUGAR. My mom used to tell me to NEVER put anything white in your mouth. Sugar, flour, rice, potatos......well mom may have been right.


37 posted on 09/05/2006 1:29:36 PM PDT by shankbear
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To: MAD-AS-HELL

Early man (caveman for those in Rio Linda) ate mostly protien and didn't have kidney problems. Fatties have become more common due to the advent of low-fat foods. The more low fat food (carbs for those in Rio Linda) that the fatties eat, the more fat they put on. Atkins is right.


38 posted on 09/05/2006 1:30:08 PM PDT by razzle
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To: Busywhiskers

Swallowing a pound of ice cubes will use up some calories.


39 posted on 09/05/2006 1:32:56 PM PDT by Right Wing Assault ("..this administration is planning a 'Right Wing Assault' on values and ideals.." - John Kerry)
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To: Fawn

I forgot to mention exercise, very true.


40 posted on 09/05/2006 1:33:06 PM PDT by Sam Cree (Don't mix alcopops and ufo's)
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To: neoken

I don't know.


41 posted on 09/05/2006 1:33:33 PM PDT by Sam Cree (Don't mix alcopops and ufo's)
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To: 2Jedismom
One thing we never NEVER use is Crisco or margarine.

This is the list of stuff I avoid:

Corn syrup, high fructose corn syrup, unfermented soy products, msg, canola oil (anything that overly processed can't be healthy), most breads and rice, potatoes.

42 posted on 09/05/2006 1:34:48 PM PDT by Tamar1973 (Don't argue with an idiot; people watching may not be able to tell the difference.)
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To: All

>>"No medical person is going to tell you to have all that saturated fat in your diet and no carbohydrates." <<

This old tired line is such bunk.
I eat carbs all the time on Atkins. Good carbs. Veggies.
I can get low carb tortillas and have great wrap sandwiches!

As for the fat, I don't eat beef or pork. Lots and LOTS of chicken and fish. They are protein too.

I haven't lost tons of weight but I haven't gained either. Being an ex-anorexic, this is a huge plus for me.


43 posted on 09/05/2006 1:37:06 PM PDT by netmilsmom (To attack one section of Christianity in this day and age, is to waste time.)
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To: razzle

Carbs feed a kind of insulin yo-yo cycle. Pretty soon, unless your blood sugar is somewhere in the stratosphere, you feel hungry.

I eat some carbs, but my diet is more meat-fresh vegetable oriented. It shifts as the weather turns cooler. Soon I will start cooking more soups, stews, and pastas.


44 posted on 09/05/2006 1:39:17 PM PDT by djf (Some people say we evolved. I say "Some did, some didn't!")
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To: shankbear

sugar isn't naturally white. There goes her theory.


45 posted on 09/05/2006 1:39:50 PM PDT by MAD-AS-HELL (Put a mirror to the face of the republican party and all you'll see is a Donkey.)
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To: Tamar1973
I lost 25 lbs on it myself.

40...more than two years ago. Still gone!

46 posted on 09/05/2006 1:41:23 PM PDT by Onelifetogive (* Sarcasm tag ALWAYS required. For some Freepers, sarcasm can NEVER be obvious enough.)
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To: 2Jedismom
Splenda

I try to avoid artificial sweeteners until they can come up with something that doesn't metabolize into weird stuff. I never believed the horror stories about aspartame (not the same as Splenda). A few years ago, I started using a lot of in on cereal and in drinks. After a few weeks, my fingers and toes started to tingle and go numb. Scared the crap out of me. I thought I had MS or something. I stopped using it. Symptoms went away in a week or so. A few months later, I thought I'd try an experiment and start using it again. Symptoms came back. Bye-bye aspartame.

47 posted on 09/05/2006 1:41:36 PM PDT by Right Wing Assault ("..this administration is planning a 'Right Wing Assault' on values and ideals.." - John Kerry)
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To: MAD-AS-HELL
yeah, a high protein diet will reduce your appetite as you deal with the pain fromt he Kidney stone you get with it. Also isn't good for your kidneys.

Neither is being a complete lardass .... so drink a lot of water to go with the diet.

48 posted on 09/05/2006 1:42:26 PM PDT by Centurion2000 (Property tax is feudalism. Income taxes are armed robbery of the minority by the majority.)
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To: dfwgator
In all things moderation.

Child abuse? Crack cocaine? Voting Dimocrat?

49 posted on 09/05/2006 1:42:55 PM PDT by Onelifetogive (* Sarcasm tag ALWAYS required. For some Freepers, sarcasm can NEVER be obvious enough.)
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To: MAD-AS-HELL

processed white I suppose. Wheat isn't white either but white bread is. Rice isn't white until the hull is removed. Avoid white processed stuff. Eat but don't be a pig.


50 posted on 09/05/2006 1:43:06 PM PDT by shankbear
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