Skip to comments.ADULT Cell Transplants Restore Vision in Mice
Posted on 11/09/2006 6:51:31 PM PST by Coleus
click here to read article
Title is incorrect and false.
how do you know?
Well, the PC crowd will now demand that the song "Three Blind Mice" be banned.
previous related thread
Blind mice treated with stem cells regain sight
--how do you know?--
I clicked on the link.
To get human retinal cells at the same stage of development, however, would involve taking stem cells from a foetus during the second trimester of pregnancy.
But Dr Robert MacLaren, a specialist at Moorfields Eye Hospital who worked on the research, said they did not want to go down that route.
He said the aim now would be to look at adult stem cells to see if they could be genetically altered to behave like the mouse retinal cells.
There are some cells on the margin of adult retinas that have been identified as having stem cell-like properties, which the team says could be suitable.
Dr MacLaren stressed it would be some time before patients could benefit from such a treatment, but he said that at least it was now a possibility.
Correct Title: Cell Transplants Restore Vision in Mice
Unfortunately, their tails were cut off later in the day by a carving-knife wielding farmer's wife.
Experiment with embryonic stem cells injected into Micheal J. Fox.
This doesn't promote the cause of destroying unborn children! We can't have this!!!!!!!!!!!!!!!!!!
Dare I suggest that in the study, n=3?
Millions of lives may be saved or extended if we can just sacrifice the holders of those superior stem cells.
Michael J. Fox might stop jerking around and Rush Limbaugh might hear without equipment.
Nancy Pelosi could grow a new face, which she sorely needs.
Obviously we have some laws to change first.
What exactly do you think is misleading? Be more specific.
Seems the cells he's using are LINEAGE cells --they are no longer totipotent (are not embryonic) and have committed to a specific lineage.
In fact, it seems to me he's SPECIFICALLY saying that earlier efforts using ES cells were problematic and that that's why they're NOT doing that, this time 'round.
Oh, OK. Yeah, I'd be cool with that. I mean, when people hear, "adult stem cells" they just hear the "stem" part only and freak out, so....I'd be cool with "cell transplants".
In fact, they should have used that terminology from the beginning, to avoid ethnical sensibilities/public ignorance.
--In fact, it seems to me he's SPECIFICALLY saying that earlier efforts using ES cells were problematic and that that's why they're NOT doing that, this time 'round.
--What exactly do you think is misleading? Be more specific.---
The above title has the word "ADULT" when in fact the cells were not taken from an adult nor are they adult stem cells. Seems the poster wants to imply something that is not true.
the term "adult" indicates the cells were not taken from embryos. the term "adult" is also used to indicate cells from umbilical cord blood, placenta and amniotic fluid. From under what rock did you just craw out? I did not say these were stem cells. Many freepers have requested from me that I use the term Adult in titles when referring to non-embryoic cells. I have yet to see you post any threads of value on the free republic, just comments that have no substance. You are being very silly and pathetic and have not contributed to this cause.
I see you did not challenge the accuracy of my post.
--Did you perhaps think that "fetal stem cells" were different from "adult stem cells"?--
I do not know what you are referring to.
The researchers said they wanted to pick them up a little bit earlier in the life cycle and then work them through to what amounts to an adult status ~ just as it happens.
They are attempting to avoid working with celltypes (embryonic stem cells) that cause cancer.
Because he just signed up 6 days ago.
--The stem cells --
They weren't stem cells.
You can call them what you want, but there they were ~ doing what stem cells do.
--You can call them what you want, but there they were ~ doing what stem cells do.--
No. Stem cells are undifferentiated.
Embryonic "stem cells" are undifferentiated, and to a degree they can do anything they wish, and no one seems to be able to do anything about it.
You go injecting embryonic stem cells into the brains of the handicapped they are going to develop into cancer.
You know that.
--Stem cells are NOT undifferentiated ~ --
Perhaps you should check your references ...
--Those cells really can't be differentiated from "adult stem cells". --
They can easily be differientiated from "adult stem cells" as these were differentiated and adult stem cells are NOT differentiated.
There's a continuum of development in stemcells, and various terms have been invented to more or less indicate the level of development.
Might be better to use those terms than to mess around with "differentiate" ~ particularly since that term has a quite ordinary meaning related to how I or you might see different things.
I am using NIH definitions.
--Just being consistent with the definitions posted at Wikipedia, I think you are trying to use "differentiate" in place of several other terms.--
Stem cells are primal cells that retain the ability to renew themselves through cell division and can differentiate into a wide range of specialized cell types.
Adult stem cells are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues.
She's already two faced...
They are not.
Actual development is directed towards harvesting the patient's own blood marrow, processing blood marrow in the operating room to extract the patient's own stem cells. These cells will be injected into the target joint. This all will take place in one procedure within the confines of the O.R.
Any clinical material either entering or leaving the O.R., triggers massive regulatory requirements. A device entering the O.R. that rearranges the patient's own cells is to the FDA only a device, which incurs a mere fraction of the regulatory burden.
"So this is an cure/therapy with embryonic stem cells?
If so, wow!"
No...here is the important factoid from the article....
"In the experiment, his team harvested these photoreceptor precursor cells from the retinas of newborn mice, whose eyes were still developing."
These were not embryonic stem cells.
"The above title has the word "ADULT" when in fact the cells were not taken from an adult nor are they adult stem cells. Seems the poster wants to imply something that is not true."
The term "adult stem cells" does not mean the cells have to come from an adult.
The term is used to refer to sources of stem cells that do not come from embryos.
Lately however, I've noticed that umbilical cord cells are being referred to as "cord cells" - but I've also seen them be referred to as adult stem cells as well.
The cells in this experiment did not come from an embryonic source.
"I just wanted to be fair and let one of the forum's ESC promoters
gloat...if indeed some ESCs had finally been tamed."
If cancerous tumors produced by embryonic stem cells don't tame them, I don't know what will.
--Wikipedia's definition seems to be leading you to believe that embryonic and adult stem cells are identical in form and nature. They are not.--
You keep making statements about me that are incorrect. Please stay with the facts.
-The cells in this experiment did not come from an embryonic source.--
They are not adult stem cells. Over and out.
"They are not adult stem cells. Over and out."
According to you.
Somehow I think I'll rely on the scientists definitions.
""They are not adult stem cells. Over and out."
I found this site gave helpful info...
The article posted for this thread suggests that stem cells later reach a stage where they have "committed" themselves to particular type of growth.
Is this what you are disputing? That once the cells became receptive to light they no longer fit the definition?
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