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Gene cure for blindness [proved successful at restoring the sight of dogs]
| David Rose
Posted on 05/02/2007 6:27:44 AM PDT by bedolido
A BRITISH hospital has made the world's first attempt to treat blindness with a revolutionary gene therapy. Surgeons at the Moorfields Eye Hospital in London operated on Robert Johnson, who was born with a rare sight disorder known as Lebers congenital amaurosis (LCA), which deteriorates with age.
Mr Johnson, 23, who had genes inserted into one eye, could see only outlines during the day and very little at night before having the procedure yesterday.
He is one of a dozen young patients selected for the first clinical trial to test the new therapy, which has already proved successful at restoring the sight of dogs in tests.
(Excerpt) Read more at theaustralian.news.com.au ...
TOPICS: Australia/New Zealand; Culture/Society; Extended News; United Kingdom
KEYWORDS: blindness; cure; gene
posted on 05/02/2007 6:27:49 AM PDT
Miracle. And no fetal stem cells?..........
posted on 05/02/2007 6:29:24 AM PDT
by Red Badger
(My gerund got caught in my diphthong, and now I have a dangling participle...............)
posted on 05/02/2007 6:31:31 AM PDT
(I can forgive you for killing my sons, but I cannot forgive you for forcing me to kill your sons)
Wonderful! This is the kind of news I like the best.
posted on 05/02/2007 6:43:43 AM PDT
by Leg Olam
("Somethings got to go, either me or that wallpaper.." last words, Oscar Wilde)
Wow... Amazing! I hope it does work.
posted on 05/02/2007 6:49:07 AM PDT
I’m disappointed, but only because of the byline. A friend was in the research race to be first to fix this and I’d hoped for an Iowa byline. The British research bureaucracy must have moved quicker. The disease won some media coverage last fall when Cubs 1B Derrick Lee’s daughter was diagnosed with it. According to my friend this is the most severe of the genetic diseases that cause blindness. There is a breed of dogs prone to the same disease which simplified the research. The dog results were stunning. The dogs were completely blind, “walking into walls” blindness my friend said. There have now been 50+ dogs treated, and they rapidly regained good eyesight without any ill effects. They can now catch thrown sock balls! The results have lasted 7+ years in them. It worked even on older dogs in whom both I and my friend would have anticipated suboptimal results because of poor development of their previously deprived optical cortex. I hope these folks will be able to report similarly good results soon.
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