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Too fat? Common virus may be to blame: study
Reuters ^ | 08/20/2007 | Julie Steenhuysen

Posted on 08/20/2007 1:44:54 PM PDT by Responsibility2nd

CHICAGO (Reuters) - A common virus caused human adult stem cells to turn into fat cells and could explain why some people become obese, U.S. researchers said on Monday.

The research builds on prior studies of adenovirus-36 -- a common cause of respiratory and eye infections -- and it may lead to an obesity vaccine, they said.

"We're not talking about preventing all types of obesity, but if it is caused by this virus in humans, we want a vaccine to prevent this," said Nikhil Dhurandhar, an associate professor at Pennington Biomedical Research Center at Louisiana State University System.

The virus adenovirus-36 or Ad-36, caused animals to pack on the pounds in lab experiments. "These animals accumulated a lot of fat," Dhurandhar said in a telephone interview.

Dhurandhar also has shown that obese people were three times more likely to have been infected with Ad-36 than thin people in a large study of humans.

Now, researchers in Dhurandhar's lab have shown that exposure to the virus caused adult human stem cells to turn into fat-storing cells.

Dr. Magdalena Pasarica, who led the study, obtained adult stem cells from fat tissue of people who had undergone liposuction. Stem cells are a type of master cell that exist in an immature form and give rise to more specialized cells.

Half of the stem cells were exposed to the virus Ad-36. After a week, most of the infected stem cells developed into fat cells, while the uninfected cells were unchanged.

Pasarica presented her findings at a meeting of the American Chemical Society in Boston.

"The virus appears to change their commitment to a fat storing cell," Dhurandhar said, adding that Ad-36 is just one of 10 pathogens linked to obesity and that more may be out there.

He acknowledged that some people might find it hard to believe that a virus could be responsible for obesity.

"Certainly overeating has something to do with gaining weight. No doubt about that. But that is not the whole truth," Dhurandhar said. "There are multiple causes of obesity. They range from simple overeating to genes to metabolism and perhaps viruses and infections."

Long term, he said he hoped to develop a vaccine and perhaps treatments for the virus. But first, he and colleagues need to better understand the role of Ad-36 in human obesity, he said.

Globally, around 400 million people are obese, including 20 million children under age 5, according to the World Health Organization.


TOPICS: Miscellaneous; News/Current Events
KEYWORDS: ad36; adenovirus36; adultstemcells; diet; health; obesity; stemcells; tr
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Are you fat?

Well it's not your fault. Just because you ate a dozen donuts for breakfast.

Now we can blame Ad-36.

1 posted on 08/20/2007 1:44:56 PM PDT by Responsibility2nd
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To: Responsibility2nd

It’s the Bigmacaccoccis virus.


2 posted on 08/20/2007 1:46:10 PM PDT by Cementjungle
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To: Responsibility2nd

That’s it!

I have a virus!


3 posted on 08/20/2007 1:46:10 PM PDT by i_dont_chat (Your choice if you take offense.)
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To: Responsibility2nd

Talk about a Mac attack. Now a big mac is a virus.


4 posted on 08/20/2007 1:47:52 PM PDT by edcoil (Reality doesn't say much - doesn't need too)
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To: Cementjungle

lol


5 posted on 08/20/2007 1:49:56 PM PDT by martin_fierro (< |:)~)
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To: Responsibility2nd

6 posted on 08/20/2007 1:50:50 PM PDT by traditional1
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To: Responsibility2nd

That’s how the libs respond to evidence that runs counter to their global warming theory.


7 posted on 08/20/2007 1:51:11 PM PDT by em2vn
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To: Responsibility2nd

How about if you eat a cup of salad greens, 6 oz of chicken and a Tbsp of low fat dressing a day and are still fat?

I know, eat less/move more. Eat less and move more til ya faint and have your hair fall out. It doesn’t matter as long as you’re thin, right?

Those who are naturally thin would have starved to death out on the prairie if bodies did not go into starvation mode.


8 posted on 08/20/2007 1:51:27 PM PDT by netmilsmom (To attack one section of Christianity in this day and age, is to waste time .)
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To: netmilsmom

I don’t think I have ever heard of anyone who consumes a diet under 1,000 calories a day being fat. I have been a part of an over-eating support group for the last year and have seen many in the group who were obese change their lives.


9 posted on 08/20/2007 1:54:47 PM PDT by Nachum
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To: Responsibility2nd

I guess it will be easy to tell who didn’t get their vaccination shot...

Off the topic a bit, but I was just driving home and happened to be checking out XM channel 4, which plays ‘40s songs. And the first thing I heard was this: “Huggin’ & Chalkin’”, by Hoagy Carmichael. I hadn’t heard of this song before, but here are the lyrics. Wow. Can you imagine something like this being written today in our PC times?

Huggin’ & Chalkin’

I got a gal who’s mighty sweet
Big blue eyes and tiny feet
Her name is Rosabelle Magee
And she tips the scales at three-oh-three

Oh, gee, but ain’t it grand to have a gal so big and fat
That when you go to hug her, you don’t know where you’re at
You have to take a piece of chalk in your hand
And hug a ways and chalk a mark to see where you began

One day I was a-huggin’ and a-chalkin’ and a-chalkin’ and a-huggin’ away
When I met another fella with some chalk in his hand
A-comin’ around the other way over the mountain
A-comin’ around the other way

Nobody ever said I’m weak
My bones don’t ache, my joints don’t creak
But I grow pale and I get limp
Every time I see my baby blimp

Oh, gee, but ain’t it grand to have a gal so big and fat
That when you go to hug her
You don’t know where you’re at
You have to take a piece of chalk in your hand
And hug a bit and chalk a mark to see where you began!

One day I was a-huggin’ and a-chalkin’ and a-beggin’ her to be my bride
When I met another fella with some chalk in his hand
A-comin’ around the other side (over that mountain)
A-comin’ around the other side
She’s a mile wide!

Chalkin’ up a markdown and yellin’ “No More!”
When I met another fella with some chalk in his hand
A-comin’ around the other side (over the mountain)
Over the Great Divide!!


10 posted on 08/20/2007 1:56:41 PM PDT by RepublitarianRoger
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To: Responsibility2nd

Filmaker Michael Moore of the Film Actors Guild immediately issued a statement blaming the U.S. health care system for failing to cure the viral infection making him fat.

11 posted on 08/20/2007 1:56:42 PM PDT by SirJohnBarleycorn
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To: RepublitarianRoger

That’s a great song!

I’ve never heard it before either.

I wonder if he uses flour?

And no... I won’t explain my question!


12 posted on 08/20/2007 2:02:34 PM PDT by Responsibility2nd
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To: All

I thought Macs couldn’t get viruses... Maybe people should have an Apple a day...

(Apologies in advance for the techie humor)


13 posted on 08/20/2007 2:04:08 PM PDT by JenBrower (...government is not the solution to our problem; government is the problem. - Ronald Reagan)
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To: Nachum

>>I don’t think I have ever heard of anyone who consumes a diet under 1,000 calories a day being fat.<<

I have. I watched my niece do it. Sooner or later when you go back to eating normally (like with bread), you gain weight. Most times, more than what you took off. How long can one eat only 1000 calories? It has to be forever.

The problem is that diets fail. Eventually, one’s body gets used to an amount of calories. Plateaus happen. People are eating salads and not losing a pound. One only has so much time to exercise.

So for some people, the eat less/move more formula works. When one has to lose 20 pounds, it works.
When one is staring at hundreds, there is something else going on.


14 posted on 08/20/2007 2:04:56 PM PDT by netmilsmom (To attack one section of Christianity in this day and age, is to waste time .)
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To: Responsibility2nd
"While a team of researchers frantically study the cause of obesity, their kids take a lunch at McDonalds..."


15 posted on 08/20/2007 2:08:10 PM PDT by avacado
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To: Responsibility2nd
Even Superman's girlfriend caught the Ad-36 virus!


16 posted on 08/20/2007 2:09:18 PM PDT by COBOL2Java (If Barbie is so popular, why do you have to buy her friends?)
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To: Nachum

my girlfriend consumes 1000 calories a day and does 30 minutes of cardio on a elliptical and she has been at it for 4 months and hasn’t lost more than 5 lbs. she has hyper or hypo thyroid issues? I swear she drinks water by the gallon and eats like a bird, does weights and cardio and can’t loose hardly any weight at all. I think she weights about 150 and is 5 feet tall. It is sad to see her work so hard and deprive herself of so much for such dismal results. Is there nothing they can do for a bad thyroid....the meds don’t seem to help at all although she says if she stops taking them she gains weight...the math just doesn’t add up!


17 posted on 08/20/2007 2:14:51 PM PDT by superfries
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To: Responsibility2nd

More evidence of the pervasiveness of junk science, hyped by attention-hungry media.


18 posted on 08/20/2007 2:17:31 PM PDT by Elpasser
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To: traditional1
Holy Jesus! What is that? What the f*** is that? WHAT IS THAT, PRIVATE PYLE?


19 posted on 08/20/2007 2:19:15 PM PDT by stm (Fred Thompson in 08! Return our country to the era of Reagan Conservatism now.)
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To: Responsibility2nd

We should not be so dismissive.

Remember the Doctors were all laughing when that Australian Doctor said ulcers were caused by a bacteria. They stopped laughing after he infected himself creating stomach ulcers and then cured himself. He won the nobel prize for medicine.

This is not for all obesity but if we can eliminate this one form then those that remain will be the emotional/self imposed obesity.


20 posted on 08/20/2007 2:19:42 PM PDT by longtermmemmory (VOTE! http://www.senate.gov and http://www.house.gov)
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To: longtermmemmory

Exactly.


21 posted on 08/20/2007 2:20:35 PM PDT by Triggerhippie (Always use a silencer in a crowd. Loud noises offend people.)
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To: em2vn

Bravo! I am going to steal your answer and use it myself. It expresses so clearly what I’ve been thinking about the glib responses to anything that talks about the causes of obesity being anything but “too much food and not enough movement”.


22 posted on 08/20/2007 2:21:41 PM PDT by nhoward14
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To: longtermmemmory

Good point.

Why are skinny people able to eat whatever they want? And not gain weight?

Why are there no drugs to affect your metabolism?


23 posted on 08/20/2007 2:21:49 PM PDT by Responsibility2nd
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To: superfries
"Is there nothing they can do for a bad thyroid....the meds don’t seem to help at all although she says if she stops taking them she gains weight...the math just doesn’t add up!"

Is she taking artificial or natural thyroid?? There are some people for whom the synthetic simply doesn't work. Switching to animal-derived (I think Armour) helps in some cases. Also, she may be lacking nutritional thyroid co-factors needed to get full benefit of the hormone.

24 posted on 08/20/2007 2:22:21 PM PDT by Wonder Warthog (The Hog of Steel-NRA)
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To: avacado

Now THAT is child abuse. No parent should ever let their children get obese like that. If it’s glandular they should be seen by a physician LONG before it ever reaches that point.


25 posted on 08/20/2007 2:24:34 PM PDT by stm (Fred Thompson in 08! Return our country to the era of Reagan Conservatism now.)
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To: superfries
does 30 minutes of cardio on a elliptical

Has she tried doing her 30 minutes of cardio on an elliptical using an HIIT routine? Studies show that using an HIIT routine is more effective at burning fat and the body continues to burn fat for hours afterward.

26 posted on 08/20/2007 2:24:58 PM PDT by SirJohnBarleycorn
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To: longtermmemmory

Being dismissive around here is commonplace.


27 posted on 08/20/2007 2:27:15 PM PDT by Leatherneck_MT (A nation of sheep will beget a government of wolves.)
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To: netmilsmom

It is too bad that alot of people pile on fat people as being solely those who overeat. I’ve been cutting back, and don’t seem to be losing alot. I’m taking responsiblity for my eating, but they aren’t open minded enough to understand that not everyone is an overeater. Nor do they understand how hurtful it is to be constantly criticized and scrutinized over everything we eat.


28 posted on 08/20/2007 2:27:31 PM PDT by oneamericanvoice (Support freedom! Support the troops! Surrender is not an option!)
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To: netmilsmom
I have. I watched my niece do it. Sooner or later when you go back to eating normally (like with bread), you gain weight. Most times, more than what you took off. How long can one eat only 1000 calories? It has to be forever.

Atkins is the only diet that has worked for me.

29 posted on 08/20/2007 2:28:03 PM PDT by Hacksaw (Appalachian by the grace of God - Montani Semper Liberi)
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To: Responsibility2nd

Not open to the possiblity that not everyone who is fat is overeating?


30 posted on 08/20/2007 2:30:25 PM PDT by oneamericanvoice (Support freedom! Support the troops! Surrender is not an option!)
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To: Elpasser

Why is it junk science? You base your assertion on what?


31 posted on 08/20/2007 2:31:25 PM PDT by oneamericanvoice (Support freedom! Support the troops! Surrender is not an option!)
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To: Leatherneck_MT

naaaaaaahhhhh.... never.

(/s)


32 posted on 08/20/2007 2:32:06 PM PDT by longtermmemmory (VOTE! http://www.senate.gov and http://www.house.gov)
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To: neverdem

ping


33 posted on 08/20/2007 2:34:48 PM PDT by raybbr (You think it's bad now - wait till the anchor babies start to vote.)
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To: netmilsmom

Here you go again with using your niece’s bad crash diet as “evidence” against the best most successful healthiest way their is to lose weight.

no a person is NOT guaranteed to go back to eating the way they did before (which if they weight 400 pounds is NOT normal eating).

A full grown adult should NEVER under ANY circumstances be eating less than 1000 calories a day. That’s a crash diet that puts a person into starvation mode which is unhealthy. Like I told you before it’s eat LESS exercise more not eat almost nothing.

The problem isn’t that diets fail it’s that PEOPLE fail. It happens all the time. Plateaus aren’t a failure, if you stick to a healthy exercise program the plateaus will end on their own after a few weeks and you will resume losing weight. In the mean time during a plateau you tend to lose girth, during my weight loss I could almost guarantee that when the scale wouldn’t budge for two weeks is when I’d have to remove a link from my watch band.

Unless a person is fighting their own genetics (and that’s a really small percentage of the people) eat less move more ALWAYS when PROPERLY applied. That means no crash dieting, that means no starvation mode, that means approaching it as a permanent change of your life so no going back to eating like “normal”. And it works GREAT for losing lots of weight. If eat less exercise more is so bad for losing lots of weight why is it that’s the EXACT method they use for morbidly obese people, sure they use surgeries to either force the person to eat less or force the person to digest less, but that’s still what they do.

you really need to stop using you and your nieces failures with crash diets as “evidence” against a good healthy way for people to lose weight. For one thing neither of you actually followed eat less exercise more, and for another the plural of anecdote is not fact.


34 posted on 08/20/2007 2:37:16 PM PDT by discostu (indecision may or may not be my biggest problem)
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To: oneamericanvoice

AMEN!
That is my point. It’s easy to sit back and say that those who are overweight ate a box of donuts this morning.

Here is my example.
I have two daughters. One is skinny, one is getting chunky.

The chunky one is the child constantly in motion. She loves veggies. We don’t do sugar in our house because I am fighting weight. No pop, no juice, low-fat milk (8 oz per meal only) She is an ice water drinker. Her idea of dessert is a peach or apple.

The skinny one is a bookworm. She eats anything she wants and only moves when her sister pulls her out. Her idea of a snack would be cake (if we had it) She and Daddy have a secret stash of candy that they eat when the little one is in bed.

So why is the little one chunky? She eats less and moves more.

It’s not quite that easy, is it?


35 posted on 08/20/2007 2:37:30 PM PDT by netmilsmom (To attack one section of Christianity in this day and age, is to waste time .)
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To: Responsibility2nd
"Now we can blame Ad-36." The authors never claimed the virus was responsible for all obesity....but perhaps a lot of it. I remember when people sneered at the notion of ulcers being caused by bacteria, too.
36 posted on 08/20/2007 2:38:36 PM PDT by DesScorp
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To: Responsibility2nd
Yeah....let's not be "dismissive" here.

Or, worse yet, look around and look at all the fat asses you know, and which have an eating habit/exercise habit that's probably got NOTHING to do with their obesity...it's a virus that will win this guy a Nobel prize.

I guess injection of common sense based on personal experience and observation is frowned upon now.

DU notoriously lacks common sense to situations, but here, we're adopting similar commentors who think common sense doesn't belong here as it's "un-scientific".

37 posted on 08/20/2007 2:39:10 PM PDT by traditional1
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To: raybbr

thanks, bfl


38 posted on 08/20/2007 2:39:35 PM PDT by neverdem (Call talk radio. We need a Constitutional Amendment for Congressional term limits. Let's Roll!)
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To: longtermmemmory
We should not be so dismissive.

Thank you. We're sooooo into personal responsibility here, that we knee-jerk to anything that flies in the face of that. It reminds me of the belief during the Middle Ages that sickness was some sort of divine retribution on a person.

Then we learned about germs.

39 posted on 08/20/2007 2:39:54 PM PDT by hunter112 (Change will happen when very good men are forced to do very bad things.)
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To: Responsibility2nd

That common virus is called “the fat mouth” virus.

The only known cure is not to overeat


40 posted on 08/20/2007 2:41:00 PM PDT by Gatún(CraigIsaMangoTreeLawyer)
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To: superfries

She’s probably not actually eating enough. If you eat too little your body goes into starvation survival mode, part of which is reducing your metabolic rate to cut down on the calories you burn, which of course is exactly what a person trying to lose weight doesn’t want to do. Of course thyroid conditions complicate everything. She just might be fighting genetics, which is a battle you can never win.


41 posted on 08/20/2007 2:41:29 PM PDT by discostu (indecision may or may not be my biggest problem)
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To: Cementjungle

LOL!!!

How about Transfatococcus?


42 posted on 08/20/2007 2:42:42 PM PDT by Paved Paradise
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To: discostu

Your opinion/my opinion. We both have a right to them.

No way can you judge how a person who is 400 pounds eats everyday. A dear friend of mine had a 10 year old on steroids for a brain tumor. She died at nearly 150 pounds. Some things are out of one’s control.

It’s not just my niece. I lived on SlimFast and was a ballerina. But the “eat less/move more” theory, I should have been dead in six months and I’m still typing.

As I stated on the last thread, your horse is pretty high.


43 posted on 08/20/2007 2:43:42 PM PDT by netmilsmom (To attack one section of Christianity in this day and age, is to waste time .)
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To: superfries

Thanks for commenting. And thanks for seeing the wonderful woman your girlfriend is, rather than just a fat person. Too bad the people who are being so cruel on this thread will never know how nice those people like your girlfriend and I are. But then we don’t bother with shallow folks anyway.


44 posted on 08/20/2007 2:44:46 PM PDT by oneamericanvoice (Support freedom! Support the troops! Surrender is not an option!)
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To: superfries

She might want to try laser liposuction. It’s the non-penetrative answer to weight loss surgery.


45 posted on 08/20/2007 2:45:16 PM PDT by Niuhuru
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To: Coleus; Peach; airborne; Asphalt; Dr. Scarpetta; I'm ALL Right!; StAnDeliver; ovrtaxt; ...

another unusual SC ping


46 posted on 08/20/2007 2:45:29 PM PDT by neverdem (Call talk radio. We need a Constitutional Amendment for Congressional term limits. Let's Roll!)
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To: Responsibility2nd

Yep. I have a friend who is a size 0 (yes, there is such a thing) and she eats anything and everything she wants... she is very fortunate to be slim without trying.

The only issues I wonder are that I NEVER saw photos of fat concentration camp or gulag survivors - EVER. So, what a coincidence, none of them were fat and apparently none of them had any of the metabolic, or thyroid, or other health issues that make one fat (????) Hmmmm.

Also, most people who ARE obese are so directly due to their higher intake than output. It’s simple math.


47 posted on 08/20/2007 2:45:39 PM PDT by Paved Paradise
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To: Hacksaw

>>Atkins is the only diet that has worked for me<<

The pity of it is that she has a nutritionist through Metro Hospital in Cleveland that has convinced her that Atkins will kill her.


48 posted on 08/20/2007 2:45:46 PM PDT by netmilsmom (To attack one section of Christianity in this day and age, is to waste time .)
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To: superfries

She should up her calories, up her fat, and lower her carbs. Rotate workouts - cardio one day, strength training the next. She’ll see the scale move and she’ll probably feel a lot better. Upping calories and fat seems counterintuitive when trying to lose weight, but really, it’s the carbs that matter. Plus she won’t feel like she’s dieting if she ups her fat intake.


49 posted on 08/20/2007 2:45:58 PM PDT by coop71 (Being a redhead means never having to say you're sorry...)
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To: superfries

Bless her efforts!!!


50 posted on 08/20/2007 2:47:16 PM PDT by netmilsmom (To attack one section of Christianity in this day and age, is to waste time .)
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