The first American colony in Jamestown 400 years ago was about to starve to death until (taking a cue from the Native Americans) they discovered the cash crop of tobacco which helped build America.
Of course, if some of the anti tobacco people were around back then, they would have put a quick stop to it.
I strongly suspect that in the event such succeeded in making tobacco consumption illegal, it would be in short order that the medical community would 'discover' benefits to the consumption thereof, heretofore unheralded, which they would quickly turn to a profit.
Apparently, the consumer saw some benefit by using tobacco, then as today, or the practice would have never become popular.
King Charles did his damndest to ban tobacco ... even then people knew it was unhealthy. But then, so is daily bathing.