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Stem Cells Help Rats Recover Function After Stroke (also help diabetes)
ABC News/Reuters ^ | Feb. 20, 2008 | Will Dunham

Posted on 02/20/2008 8:28:41 PM PST by FocusNexus

Transplanting brain cells produced from human embryonic stem cells helped fix stroke damage in the brains of rats, according to scientists who hope to test the same thing in people within about five years.

Researchers have been looking for ways to repair the brain damage from a stroke, which can cause permanent disability. In a study published on Tuesday, researchers at Stanford University School of Medicine in California reported that treatment involving human embryonic stem cells may be a solution.

The transplanted cells helped repair the stroke damage and enabled the rats to recover lost function in front legs weakened as a result of the stroke, they added.

"It was not quite back to normal but, at least in the rat, it looks like it's going to be close to normal -- very impressive," Steinberg said.

Some people oppose the use of human embryonic stem cells on ethical grounds because creating the reservoirs of these cells for use in research involves the destruction of human embryos.

(Excerpt) Read more at abcnews.go.com ...


TOPICS: Culture/Society; Extended News
KEYWORDS: abortion; deathindustry; diabetes; embryos; geneticcannibalism; health; humanembryos; infanticide; medicine; science; stemcells; stroke
Direct link to study results

Link to article at ABC News (in my main link, I gave the link to the print version, so it's all on one page)

Here is the other article about use of stem cells to cure diabetes (rather than post a separate thread):

Researchers Use Embryonic Stem Cells to Treat Diabetes

Doctors may be one step closer to using stem cells to cure diabetes, according to a new study by researchers at the stem cell engineering company Novacell, Inc. in San Diego who report that they managed to convert human embryonic stem cells into insulin-producing cells.

Insulin is the chemical produced in the pancreas that allows the body to regulate blood-sugar levels — and it is precisely the substance that many of those with diabetes lack.

The researchers, who reported their findings in the journal Nature Biotechnology, found that when they injected these human cells into diabetic mice, the treatment alleviated diabetes in the rodents.

1 posted on 02/20/2008 8:28:44 PM PST by FocusNexus
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To: FocusNexus

Good for the critters. It’s the Year of the Rat, after all.


2 posted on 02/20/2008 8:29:55 PM PST by rfp1234 (Phodopus campbelli: household ruler since July 2007.)
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To: FocusNexus

Great advance! For the first time in my adult life, I am proud of this country! [/rat]


3 posted on 02/20/2008 8:32:35 PM PST by ClearCase_guy
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To: FocusNexus
Stem Cells Help Rats Recover Function After Stroke (also help diabetes)

Fund it! Think of all the people who can be employed rounding up and injecting the rats in NYC alone!

4 posted on 02/20/2008 8:34:11 PM PST by the invisib1e hand (unavailable for comment)
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To: All; FocusNexus; wagglebee; floriduh voter; cpforlife.org

“Some people oppose the use of human embryonic stem cells on ethical grounds because creating the reservoirs of these cells for use in research involves the destruction of human embryos.”

Bad news for HUMAN LIFE!


5 posted on 02/20/2008 8:38:02 PM PST by Sun (Duncan Hunter:pro-God/life/borders, understands Red China threat, NRA A+rating!)
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To: FocusNexus

This only works in Rats?? No hope for Republicans or other conservatives?


6 posted on 02/20/2008 9:01:10 PM PST by dodger
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To: dodger

I know you were just kidding — but “who hope to test the same thing in people within about five years. “


7 posted on 02/20/2008 9:03:31 PM PST by FocusNexus ("Winning isn't everything, it's the only thing." -- Vince Lombardi)
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To: Sun
I had a stroke a little over a year ago and still have residual effects. That said,you can count me in with the "some people oppose" group.

“Some people oppose the use of human embryonic stem cells on ethical grounds because creating the reservoirs of these cells for use in research involves the destruction of human embryos.”

8 posted on 02/20/2008 9:07:28 PM PST by A message
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To: FocusNexus

In the days of Antichrist, all of Christ’s miracles will be reproduced, save that the dead will not be raised.


9 posted on 02/20/2008 9:08:42 PM PST by The_Reader_David (And when they behead your own people in the wars which are to come, then you will know. . .)
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To: FocusNexus

There are no brain cells in embryonic stem cells. ESCs are pluripotent (or whatever) and havent developed in any specific organ yet.

This is very good news though. I hope it works.


10 posted on 02/20/2008 9:18:24 PM PST by OmegaMan
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To: A message

I’ve had a disability for ten years, and had to quit a job I loved because of it, but, if I could, WOULD NOT ALLOW AN EMBRYO TO BE KILLED to benefit my life.

Regards,

Sun

(former embryo)


11 posted on 02/20/2008 9:19:51 PM PST by Sun (Duncan Hunter:pro-God/life/borders, understands Red China threat, NRA A+rating!)
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To: FocusNexus

“human embryonic stem cells helped fix stroke damage in the brains of rats”

So why can’t we try using the embryonic stem cells of rats (or say dolphins) in HUMANS?

Since this seems to work across species...


12 posted on 02/20/2008 9:23:53 PM PST by weegee (Those who surrender personal liberty to lower global temperatures will receive neither.)
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To: dodger

The sooner Republicans die, the sooner the DNC can have them vote for Democrats.


13 posted on 02/20/2008 9:24:55 PM PST by weegee (Those who surrender personal liberty to lower global temperatures will receive neither.)
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To: Mrs Zip

ping


14 posted on 02/20/2008 10:14:47 PM PST by zip (((Remember: DimocRat lies told often enough become truth to 48% of all Americans (NRA)))))
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To: FocusNexus

We are entering a new medical age that will see what will seem like miracles when many lifes are saved and or improved with gene therapies. It’s quite exciting.


15 posted on 02/20/2008 10:58:12 PM PST by DoughtyOne (We've got Tweedle Dee, Tweedle Dumb & Tweedle Dumber left. Name them in order. I dare ya.)
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To: DoughtyOne

There’s now, and finally, a Cleveland hospital using the patient’s own stem cells to use in healing his own cardiac conditions. Before this, the procedure was performed in Bangkok, making it a very long trip for American cardiac patients to take.

With this procedure occurring now, it’s only a matter of time before other organs can be repaired in the same manner. Good news indeed.


16 posted on 02/20/2008 11:19:47 PM PST by nuancey
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To: nuancey

I agree with your comments. Did you read that article the other day here, where they addressed the tip of a finger (about 1/4 inch) being induced to grow back? The fingernail and all came back. The article went on to address other tissues that could be helped in this manner including heart tissue and other areas of interest.

It was a great read, providing a lot of hope for the future.


17 posted on 02/20/2008 11:25:36 PM PST by DoughtyOne (We've got Tweedle Dee, Tweedle Dumb & Tweedle Dumber left. Name them in order. I dare ya.)
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There's all sorts of research going on in the field of using stem cells for strokes.

Stem cell transplants 'may benefit stroke victims' Monday, 28 Jan 2008 12:56

Stroke victims could see their condition improve after receiving stem cell transplants, two separate studies have concluded today.

Both studies saw transplanted stem cells successfully migrate and one noted significant reductions in cell death.

They are published today in the journal Cell Transplantation [snip]

Commenting on the findings, Cell Transplantation associated editor De Cesar Borlongan said: "Both studies lend important support to a growing body of laboratory evidence that bone marrow is a remarkable adult stem cell source for transplant therapy following stroke.

MultiStem for Stroke
MultiStem is a biologic product that consists of undifferentiated human stem cells obtained from adult bone marrow or other non-embryonic tissue sources. The cells may be produced on a large scale for future clinical use and stored in frozen form until needed. Material from a single qualified donor may be used to produce hundreds of thousand or even millions of clinical doses of MultiStem, which are extensively characterized to ensure product consistency and safety.

18 posted on 02/21/2008 1:32:41 AM PST by syriacus (Mrs. Obama's Little Book of Etiquette says it's NOW acceptable to be REALLY proud of being American.)
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To: FocusNexus; wagglebee; narses
From the other article quoted:
"Moreover, one of the biggest concerns about injecting patients with embryonic stem cells is that these cells have the potential to develop into cancerous tumors.

"The study does show that these [human embryonic stem cells] might have developed to a point where they appear to be no longer [tumor-forming]," said Dr. Bryon Petersen, associate professor in the department of pathology at the University of Florida College of Medicine. "This is a good thing, but what needs to follow is just how long will these cells stay fully differentiated — to make these cells no longer a threat to the patient's long-term health."

Seems that I've heard the issue of tumors once or twice before...with other "prospective" therapies that have since been abandoned. Seems the tumor issue hasn't come up with cord-blood stem cells or adult stem cells, though.

19 posted on 02/21/2008 3:24:50 PM PST by markomalley (Extra ecclesiam nulla salus)
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To: weegee

All too true ... the DNC death-vote!!


20 posted on 02/21/2008 9:26:59 PM PST by dodger
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To: DoughtyOne

I missed that article on the finger tip regeneration. Do you know the title of that thread? So many good things are on the horizon now in medicine that I think most of us will be dazzled by these accomplishments in as little as the next few years.


21 posted on 02/22/2008 11:00:03 PM PST by nuancey
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