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Selenium May Help Clarify Racial Differences in HT (hypertension, i.e. high blood pressure)
Family Practice News ^ | 1 October 2008 | SHARON WORCESTER

Posted on 11/07/2008 6:54:26 PM PST by neverdem

NEW ORLEANS — Reduced serum selenium is an independent predictor of hypertension, according to an analysis of data from the third National Health and Nutrition Examination Surveys.

The findings from this and other studies, that serum selenium concentrations are reduced in African Americans, compared with those in with whites, may in part explain the increased incidence of hypertension in African Americans, Dr. Chizobam Ani said in a poster at a meeting sponsored by the International Society on Hypertension in Blacks.

Serum selenium is an essential component in substances shown to mediate the incidence of cardiovascular disease, such as glutathione peroxidase and homocysteine. In 9,881 nonpregnant participants aged 40 years and older, researchers noted significant differences in serum selenium concentrations between African Americans and whites at the highest and lowest quartile concentrations, reported Dr. Ani of Charles Drew University of Medicine and Science, Los Angeles.

On bivariate analysis, there was a significant association between serum selenium concentration and the prevalence of hypertension and other cardiovascular disease, including peripheral vascular disease, myocardial infarction, and congestive heart failure.

An analysis that controlled for known predictors of cardiovascular disease, including family history, diabetes, sociodemographic variables, and renal disease, showed a significant relationship between serum selenium and the prevalence of hypertension (odds ratio 1.30) and a significant interaction effect between ethnicity and serum selenium in individuals with hypertension (OR 1.10).

These findings are important because African Americans have higher rates of hypertension and mortality from heart disease and stroke than do whites and Hispanics in the United States, and because African American men have three times the risk of sudden death as do white men.

Based on the emerging understanding of the role of serum selenium in hypertension and cardiovascular disease, and the differing concentrations in African Americans and whites, Dr. Ani and his colleagues theorized that high serum concentrations of selenium might predict reduced levels of oxidate stress and vascular injury in certain ethnic groups that correlates with the incidence of cardiovascular diseases.

The current findings seem to support this theory of “differential oxidative protection for cardiovascular injury” in African Americans, compared with whites, he said in an interview. The findings are of interest because low serum selenium concentration is a modifiable risk factor, he said.

TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: health; highbloodpressure; hypertension; medicine; selenium

1 posted on 11/07/2008 6:54:27 PM PST by neverdem
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To: neverdem

Eat oatmeal not potato chips for breakfast

2 posted on 11/07/2008 6:58:11 PM PST by yldstrk (My heros have always been cowboys--Reagan and Bush)
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To: yldstrk oatmeal...not cornflakes for breakfast...

3 posted on 11/07/2008 6:59:30 PM PST by goodnesswins (CONSERVATIVES....saving America's A** whether you like it or not!)
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To: neverdem

Nice to see that Someone is showing that something OTHER than a PRESCRIPTION MEDICINE is actually GOOD FOR YOU

4 posted on 11/07/2008 7:00:50 PM PST by gwilhelm56 (HITLER offered Hope and Change!!)
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
Honda 'bicycle legs' ease stress of walking (real power walk)

Europe in Full Retreat on Climate Plan, US to Follow Suit (Carbon Trading Fails Market Test)

Dietary Guidelines Implicated in Obesity Epidemic

FReepmail me if you want on or off my health and science ping list.

5 posted on 11/07/2008 7:50:47 PM PST by neverdem (Xin loi min oi)
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