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Study: Swine Flu Resembles 1918 Virus
Fox News ^ | July 13, 2009 | Reuters

Posted on 07/13/2009 11:15:14 AM PDT by AngieGal

The new H1N1 influenza virus bears a disturbing resemblance to the virus strain that caused the 1918 flu pandemic, with a greater ability to infect the lungs than common seasonal flu viruses, researchers reported on Monday.

Tests in several animals confirmed other studies that have shown the new swine flu strain can spread beyond the upper respiratory tract to go deep into the lungs — making it more likely to cause pneumonia, the international team said.

In addition, they found that people who survived the 1918 pandemic seem to have extra immune protection against the virus, again confirming the work of other researchers.

"When we conducted the experiments in ferrets and monkeys, the seasonal virus did not replicate in the lungs," said Yoshihiro Kawaoka of the University of Wisconsin, who led the study.

The H1N1 virus replicates significantly better in the lungs."

The new swine flu virus has caused the first pandemic of the 21st century, infecting more than a million people, according to estimates, and killing at least 500. The World Health Organization says it is causing mostly moderate disease but Kawaoka said that does not mean it is like seasonal flu.

"There is a misunderstanding about this virus," he said in a statement. "There is clear evidence the virus is different than seasonal influenza."

Writing in the journal Nature, Kawaoka and colleagues noted that the ability to infect the lungs is a characteristic of other pandemic viruses, especially the 1918 virus, which is estimated to have killed between 40 million and 100 million people.

(Excerpt) Read more at foxnews.com ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: 1918; flu; h1n1; influenza; swineflu; virus

1 posted on 07/13/2009 11:15:14 AM PDT by AngieGal
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To: AngieGal
Might be, but think about the state of medical care and hygiene in 1918. You couldn't drink the water in 80% of the country. There is no real similarity at all.
2 posted on 07/13/2009 11:17:42 AM PDT by xcamel (The urge to save humanity is always a false front for the urge to rule it. - H. L. Mencken)
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To: AngieGal

Swine Flu- Gore and his croonies cure for Global Warming.


3 posted on 07/13/2009 11:18:26 AM PDT by VicVega (Join Jihad, get captured by the US and resettled in the best places in the world. I love the USA)
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To: AngieGal

1918 lets see, a war was going on, there were no antibiotics, hygiene was different (in the USA).


4 posted on 07/13/2009 11:20:19 AM PDT by edcoil (If I had 1 cent for every dollar the government saved, Bill Gates and I would be friends.)
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To: AngieGal
What do they mean by “survivors of the 1918 flu had extra immune protection”?
5 posted on 07/13/2009 11:21:14 AM PDT by Ditter
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To: edcoil

You also had a whole lot more people who were rural, and able to stay home, avoid crowds, and take care of themselves and family members

And no global jet travel where a person sick in Hong Kong could be in NYC 18 hours later

Face it, the greatest medical system in the world can’t put tens of thousands of people on respirators, even if it would keep them alive. And most Americans will find it very hard to stay hunkered down at home for weeks if schools and grocery stores are closed


6 posted on 07/13/2009 11:24:31 AM PDT by silverleaf (Save the earth. It's the only planet with chocolate!)
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To: Ditter
What do they mean by “survivors of the 1918 flu had extra immune protection”?

They're immortal, which is why the scientists can still use them for research....

7 posted on 07/13/2009 11:24:56 AM PDT by r9etb
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To: AngieGal
When we conducted the experiments in ferrets and monkeys...

Ferrets?

8 posted on 07/13/2009 11:25:38 AM PDT by r9etb
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To: Ditter
"What do they mean by “survivors of the 1918 flu had extra immune protection”? "

They mean people who were alive in 1918, and were exposed to the Spanish Flu and have survived until today seem to have added immunity protection against H1N1 that people who weren't exposed to Spanish Flu don't.

9 posted on 07/13/2009 11:25:49 AM PDT by OldDeckHand (No Socialized Medicine, No Way, No How, No Time)
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To: AngieGal

Well, not to get paranoid, but I have to wonder if something didn’t escape from one of the labs that were investigating the 1918 Spanish Influenza.


10 posted on 07/13/2009 11:27:44 AM PDT by Cicero (Marcus Tullius)
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To: edcoil

In 1918, we also did not have millions of people with HIV, AIDs and 3rd world immigrants who are sitting ducks and vectors for other diseases of opportunity that will accompany a flu pandemmic, My G Grandmother survived the 1918 flu but was brain damaged by encephalitis


11 posted on 07/13/2009 11:28:12 AM PDT by silverleaf (Save the earth. It's the only planet with chocolate!)
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To: xcamel

Add the lack of indoor plumbing & no anti-biotics. That is who the swine flu will hit the hardest - Those in the world who are still living like it’s 1918.


12 posted on 07/13/2009 11:28:37 AM PDT by Sioux-san
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To: AngieGal

If it just kills old people and the infirmed, Obama will take credit for it as part of his cost-saving health care plan.


13 posted on 07/13/2009 11:29:20 AM PDT by CharlesWayneCT
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To: Ditter

Those that has the flu in 1918 and survived still carried antibodies 70-80 years later, is how I read it.


14 posted on 07/13/2009 11:29:49 AM PDT by Cathy
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To: silverleaf
"Face it, the greatest medical system in the world can’t put tens of thousands of people on respirators, even if it would keep them alive. And most Americans will find it very hard to stay hunkered down at home for weeks if schools and grocery stores are closed"

That's exactly right. I have no idea how this latest pandemic compares to 1918. But, if that 1918 Flu would have happened today, instead of then, it would still be very, very deadly. It probably wouldn't be as deadly as it was 100 years ago because of advances as distribution of modern medicine, but millions would be dead in America, and tens or hundreds of millions globally. An influenza with a 3.5% mortality rate (like the Spanish Flu), would be devastating today.

15 posted on 07/13/2009 11:30:25 AM PDT by OldDeckHand (No Socialized Medicine, No Way, No How, No Time)
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To: Sioux-san
"Add the lack of indoor plumbing & no anti-biotics."

In point of fact, the H1N1 virus, well it's a virus. Antibiotics have no effect on viruses. However, there are two antivirals available today that have shown to be effective against this latest strain, save for two known cases (one in Europe and one in San Francisco) that appear to be drug-resistant.

16 posted on 07/13/2009 11:32:59 AM PDT by OldDeckHand (No Socialized Medicine, No Way, No How, No Time)
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To: All

I have been sick with a lung issues and coughing for the last three weeks. I am starting to suspect H1N1, I was sick earlier for a few weeks with something before this latest bout.


17 posted on 07/13/2009 11:34:44 AM PDT by GraceG
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To: CharlesWayneCT
Actually, it is a type of flu that causes a “cytokine storm” so that those with the strongest immune systems die the fastest- in 1918, the young and healthy got sick and died in a day. Not that those with compromised immune systems fare much better. But I read one study that anti-arthritis drugs (which suppress the immune system) showed some good effect

history
http://www.riskinstitute.org/peri/images/file/Lessons_from_1918_PartI.pdf

18 posted on 07/13/2009 11:35:04 AM PDT by silverleaf (Save the earth. It's the only planet with chocolate!)
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To: AngieGal

duh....one flu virus resembles another one....both have protein coats and strands of DNA inside...time to shell out the next Pulitzer Prize for Journalism!


19 posted on 07/13/2009 11:38:16 AM PDT by Buckeye McFrog
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To: AngieGal

If they make it MANDATORY that all Americans receive the vaccine, then I do not want it.


20 posted on 07/13/2009 11:39:26 AM PDT by Saundra Duffy (For victory & freedom!!!)
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To: silverleaf

part II
http://www.riskinstitute.org/peri/images/file/Lessons_from_1918_PartII.pdf


21 posted on 07/13/2009 11:39:41 AM PDT by silverleaf (Save the earth. It's the only planet with chocolate!)
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To: xcamel
“Might be, but think about the state of medical care and hygiene in 1918. You couldn't drink the water in 80% of the country. There is no real similarity at all.”

Adding to that, was in 1918 there were soldiers coming and going on on crowded troops and rail cars bringing all sort of bugs with them. And in 1918 there was no such thing as Penicillin which would combat the infections that killed most of the people.

22 posted on 07/13/2009 11:40:10 AM PDT by NavyCanDo (Stop Freakin, Try Freepin)
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To: AngieGal

I’m still not taking the vaccine.


23 posted on 07/13/2009 11:41:50 AM PDT by Sig Sauer P220 (Forget going Galt. Its time to go Braveheart.)
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To: NavyCanDo
the 1918 flu cast forward in time is just another ‘boogy man’ to keep the sheeple horrified at what will never happen.

Another mass pandemic will not be flu, but another vector no one will see coming...

24 posted on 07/13/2009 11:42:38 AM PDT by xcamel (The urge to save humanity is always a false front for the urge to rule it. - H. L. Mencken)
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To: NavyCanDo
"And in 1918 there was no such thing as Penicillin which would combat the infections that killed most of the people. "

Unfortunately, the people who died in 1918 either died from Cytokine Storms or from viral pneumonia. Penicillin would not have, nor any other antibiotic, had any effect on either of those conditions.

The Cytokine storm essentially is your own body's immune system going into a kind of overdrive, producing an physiological environment where you drown in your own fluids.

There are two kinds of pneumonia, viral and bacterial. Antibiotics are an effective therapeutic treatment for bacterial infections, but are completely ineffective against viral infections.

25 posted on 07/13/2009 11:47:18 AM PDT by OldDeckHand (No Socialized Medicine, No Way, No How, No Time)
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To: NavyCanDo

Penicillin would have been useless against a viral infection anyway....


26 posted on 07/13/2009 11:48:25 AM PDT by sinsofsolarempirefan
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To: xcamel

It is a curious fact that the vicitms of the 1918 pandemic in the US were exhumed a short few years ago, to study that disease, and now a flu disturbingly similar to that killer has surfaced in the world populations.


27 posted on 07/13/2009 11:52:03 AM PDT by MHGinTN (Believing they cannot be deceived, they cannot be convinced when they are deceived.)
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To: Saundra Duffy

I won’t either. In fact, I’ve never had a flu shot. I have however had a pneumonia shot. Don’t know how well it will work should the worst befall me, but I sure hope it works well. There’s just something about those flu shots that don’t seem right to me.....


28 posted on 07/13/2009 11:52:57 AM PDT by Grumpybutt (We're witnessing/suffering through the 3rd terrorist attack and most don't even know it.)
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To: Grumpybutt
I have however had a pneumonia shot

What is that?
29 posted on 07/13/2009 12:49:12 PM PDT by Zechariah_8_13 ("If we give the bureaucrats our children, we may as well give them everything else." - J. G. Machen)
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To: silverleaf
Face it, the greatest medical system in the world can’t put tens of thousands of people on respirators, even if it would keep them alive. And most Americans will find it very hard to stay hunkered down at home for weeks if schools and grocery stores are closed

Bingo.
30 posted on 07/13/2009 12:53:40 PM PDT by PA Engineer (Liberate America from the occupation media.)
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To: NavyCanDo
Here is a fairly decent reference from Wiki on Cytokine Storm. This is a serious threat. Not only does it resemble the 1918 Flu (spanish), but is following the same seasonal infection patterns. Many who have been hospitalized with this virus have been young and on ventilators.
31 posted on 07/13/2009 1:01:53 PM PDT by PA Engineer (Liberate America from the occupation media.)
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To: Zechariah_8_13

Vaccine to help prevent pneumonia. I think it protects against 4 types if I remember right. This past winter was the first in 5 years I didn’t get pneumonia so I guess it works.


32 posted on 07/13/2009 1:02:48 PM PDT by Grumpybutt (We're witnessing/suffering through the 3rd terrorist attack and most don't even know it.)
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To: OldDeckHand

I know that antibx don’t work on viruses, but tried to make the point that people’s living circumstances can affect their clinical outcome. I may become sick with the swine flu virus, but I don’t think I am going to die from it due to my living environment and my access to the vaccine. I could be totally wrong on this. Check in next fall when it’s supposed to get ugly.


33 posted on 07/13/2009 1:35:04 PM PDT by Sioux-san
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To: Sioux-san
Don't misunderstand, I think you make good points. There are quality of life issues, like general health, diet, access to clean water, general sanitation as well as access to health care that are profoundly material when dealing with disease on either a singular or pandemic level. And, as you point out, many of those quality of life drivers are much improved from 90 years ago.

Having said that, although this particular strain of H1N1 in our current pandemic doesn't seem to have the lethality of 1918, it doesn't mean it can't mutate and become much more virulent (although it's pretty virulent now) and more lethal. Also, if the lethality increases, our own medical system would become quickly overrun with diseased patients and would be unable to cope with a truly lethal disease. There's only so many ventilators in the country.

Lastly, although medicines have become exponentially more effective since 1918, there still isn't a cure, or an effective treatment for a cytokine storm. In fact, it's still not entirely clear how this phenomenon actually works or what specifically triggers it. I think that this is what worries virologists today.

34 posted on 07/13/2009 1:53:53 PM PDT by OldDeckHand (No Socialized Medicine, No Way, No How, No Time)
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To: sinsofsolarempirefan
“Penicillin would have been useless against a viral infection anyway....”

It was bacteria, not the the flu virus itself that caused nearly all deaths in the 1918 flu. Secondary bacterial infections, especially pneumococcus and staph. All treatable today with antibiotics.

35 posted on 07/13/2009 3:40:56 PM PDT by NavyCanDo (Stop Freakin, Try Freepin)
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To: NavyCanDo; xcamel; AngieGal

You said — And in 1918 there was no such thing as Penicillin which would combat the infections that killed most of the people.

I don’t know about that. It doesn’t seem to me, that if that 1918 flu virus took hold again, that it would be easily handled as some might think.

My grandmother was telling me that people were dropping like flies in the street, which I thought was colorful language, until I found out years later that they were. People would be showing no symptoms in the morning and later in the day would be dead. People were walking on the streets and dropping dead. There were body carts sent around to pick up dead bodies in the streets (we’re talking about here).

She was also telling me that all her neighbors had dead kids from it. But, fortunately for our family, we didn’t have any.

When people are dropping like flies in the street, feeling fine in the morning and dead by the end of the day, that doesn’t give a lot of time to react. And thus, that kind of process would cause a lot of deaths.

I think that’s why many are pushing for widespread vaccinations. There’s no time to react and do something about it after the fact of developing the symptoms, if it’s like it was in 1918.


36 posted on 07/15/2009 6:40:18 AM PDT by Star Traveler (The God of Abraham, Isaac and Jacob is a Zionist and Jerusalem is the apple of His eye.)
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To: Star Traveler
Every time I bring up that we did not have antibiotics in 1918, most notible Penicillin, I get replies that it would have been useless against a viral infection.

It was Secondary bacterial infections, especially pneumococcus and staph that caused nearly all deaths in the 1918 flu. All treatable today with antibiotics if caught early enough. I am not saying the new swine flu will not kill many if we have a fall outbreak, but how much worse will it be than a normal flu season which kills tens of thousands every year is anyones guess.

37 posted on 07/15/2009 8:56:44 AM PDT by NavyCanDo (Stop Freakin, Try Freepin)
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To: NavyCanDo

You asked — I am not saying the new swine flu will not kill many if we have a fall outbreak, but how much worse will it be than a normal flu season which kills tens of thousands every year is anyones guess.

Well.., considering that this is considered the first pandemic declared since the Hong Kong flu in 1968, I would say it’s obviously on track for being “big”... :-)


Flu declared a pandemic
WHO’s heightened alert cites virus’s global spread

By David Brown and William Branigin

THE WASHINGTON POST
2:00 a.m. June 12, 2009

WASHINGTON – The World Health Organization yesterday raised its alert level for swine flu to Phase 6, declaring the first influenza pandemic of the 21st century as the virus continues to spread around the globe.

The Geneva-based U.N. agency said it decided to go to its highest warning level for the H1N1 strain – meaning that the outbreak has become a full-scale pandemic – after holding an emergency meeting with flu experts. It was the first flu pandemic declared by the WHO since 1968, when the Hong Kong flu broke out and ultimately killed about 1 million people worldwide.

“This means the world is moving into the early days of its first influenza pandemic in the 21st century,” WHO Director General Margaret Chan said.


http://www3.signonsandiego.com/stories/2009/jun/12/1n12flu0130-world-alert-over-swine-flu/?uniontrib


38 posted on 07/15/2009 9:14:19 AM PDT by Star Traveler (The God of Abraham, Isaac and Jacob is a Zionist and Jerusalem is the apple of His eye.)
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To: silverleaf

in 1918, it was young and healthy people who died.


39 posted on 07/16/2009 7:47:08 AM PDT by PghBaldy (http://www.blackfive.net/main/2009/06/president-obama-visits-wounded-troops.html)
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To: xcamel

Great tag line.


40 posted on 07/20/2009 10:18:07 AM PDT by DeltaZulu
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To: DeltaZulu
Swine Flu Resembles 1918 Virus ...

Ya, especially the death rate, not, move on ...
41 posted on 07/20/2009 10:20:35 AM PDT by Scythian
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