Skip to comments.Caffeine May Prevent and Help Reverse Alzheimer's Disease
Posted on 08/02/2009 6:31:50 PM PDT by SmartInsight
In experiments with lab mice especially bred to develop symptoms of Alzheimer's disease, University of South Florida (USF) researchers at the Florida Alzheimer's Disease Research Center ADRC gave the aged animals the equivalent of the caffeine in five cups of coffee a day. The results? Their severe memory impairment was reversed.
This study, along with other AD research by the same group of scientists, was just published in the Journal of Alzheimer's Disease. Both studies show that caffeine significantly decreased abnormal levels of beta amyloid (the protein linked to AD) in both the brains and blood of lab rodents who had symptoms of Alzheimer's. This research follows on the heels of previous ADRC research that found caffeine given to this same strain of mice when they were young prevented memory problems from developing -- even though the animals were bred to develop Alzheimer's symptoms as they grew old.
(Excerpt) Read more at naturalnews.com ...
Everything in moderation, of course.
More study will probably turn up subgroups of people helped by such things. My sainted aunt, an avid coffee drinker all her life, perished not too long ago with severe Alzheimer’s dementia.
My father died of Alzheimer’s Disease. He drank 5-6 cups of coffee a day.
Thanks for sharing — sorry about your Aunt.
I was just thinking that they shoudl do a survey of lifetime coffee drinking habits of Alzheimer patients.
Clearly it’s not that simple, but as you said, there may be a subgroup that is helped, or coffee is one component, but other things are needed as well.
Well there ya go. It only works in mice.
Let's not go that far!
IMO, your genetic makeup is much more important than your food and/or drink intake.
Where do the mice get their tiny little coffee cups?
Same for me, my dad loved and drank a great deal of coffee and still Alzheimer’s got to him.
My 100 (yes, 100) year old grandmother just passed her driver’s exam.
She gets up in the middle of the night, brews a cup of coffee and goes back to bed.
A mouse needs 5 cups a day. So a human would need the caffeine in several thousand cups.
40 cups in a short period can be lethal. 1000 would kill you. Those mice must have been wired or dead!
My Grandfather (on dads side) drank heavily and smoked his entire lie. He ate bacon and eggs every day for breakfast dug ditches for the power company...he died at 101 years of age. My dad was a carpenter, drank everyday, smoked, ate what ever he wanted...died at 98 of a heart attack. My Grandfather on moms side died of the flu at 45 and all his kids (except mom) died young of one thing or another. Genetics means everything.
My m-i-l, whose faith prohibited the use of caffiene, has early late stage Alzheimers. She is in a secure nursing home (heartbreakingly, she wanders and wants to go ‘home’). She is in a monitored unit (and had to be ‘braceleted’ when she was hospitlized months ago for another health issue).
Her sister, same religious constraints, also had Alzheimers (she has passed away). I think genetics figures into this more than lifestyle choices.
I can’t wait until they announce that a daily dose of cigarettes, beer and unprotected sex with everything alive will make you immortal.
Nice to know that I may have 40+ more years of this torture
“Where do the mice get their tiny little coffee cups?”
Lab animals are given their caffeine just as bond traders get theirs - by IV, of course!
Good point, and science and data proves it...
It appears that everything will cure anything in mice. There are many mice cancer cures that don’t work in humans.
| I just had myself
a double helping of that
newfangled brain juice!
But the health nazis will soon make you pay additional taxes for sodas, etc.
Pass the Pepsi!!!
You have a good point. I recall a study of a drug that helped some members of the study group, but had no effect on the rest. The parties "helped" had a genetic deficiency that was overcome in the presence of the drug. The other parties didn't have a deficiency, thus were neither helped or harmed by the drug.
It is very exciting that they were able to reverse Alzh.D. in the lab animals, and I'll be very interested to learn the results of their soon-to-be-conducted human trials with caffeine.
I wonder how many people are now supplementing with either No-Doz or with generic caffeine pills?
Posting for quick cross reference to another thread in which caffeine in the form of "No-Doz" & Alzheimer's plaques was discussed.
The lab animals were given what would be the EQUIVALENT of giving humans 5 cups of coffee.
One thing that researchers and commentators forget to mention is that there is great variation in the amount of caffeine in different roasts of coffee, and also in different preparations.
For instance, expresso is brewed so quickly, that although it tastes very strong, it's not very high in caffeine.
Likewise, heat can destroy caffeine, so a dark french roast, so popular today, has less caffeine to it's equivalent cup of breakfast coffee brewed decades ago.
For many years it has been known that the incidence of both Parkinson's Disease and the various dementias, including Alzheimer's has been greater in NON-coffee drinkers, but they've never been able to explain why.
I hope to hear more news about human trials they are setting up with Alzheimer's patients and caffeine.
I know nothing else about this test - particularly WHY it was developed, nor who it is popular with.
What you said is correct, of course, but they could have worded it better. For example, the way you worded it.
Reporting about medical research seems to require that one be a very poor writer, and also, that one not put too many facts into the article, and also make sure that it isn't very interesting.