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Health warning over statin taken by millions (Simvastatin)
Daily Telegraph ^ | 03/20/10 | Rebecca Smith

Posted on 03/20/2010 4:54:22 PM PDT by TennesseeGirl

Simvastatin is taken by around three million people in order to lower their cholesterol and reduce the risk of having a heart attack.

However an analysis of clinical trial data in America has found that high doses can cause muscle damage and a rare condition which induces kidney problems and may be fatal.

Patients were told not to stop taking simvastatin but advised to talk to their doctor if they have concerns.

The American medicines regulator, the Food and Drug Administration, has issued a warning to patients to be alert to signs of problems when taking the 80mg daily dose of simvastatin. It has also listed drugs that should not be prescribed to those on high doses of statins. (excerpted)

(Excerpt) Read more at telegraph.co.uk ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: cholesterol; statin; zocor
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Simvastatin is also known as Zocor. Also, "The addition of fenofibrate to simvastatin therapy failed to reduce the rate of fatal and nonfatal cardiovascular events in patients with diabetes, according to new results of the ACCORD Lipid Trial." http://www.endocrinetoday.com/view.aspx?rid=61934
1 posted on 03/20/2010 4:54:22 PM PDT by TennesseeGirl
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To: TennesseeGirl

ALL Statins are Neurotoxins...

I cant take them because of that.


2 posted on 03/20/2010 4:56:33 PM PDT by Vaquero (BHO....'The Pretenda from Kenya')
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To: TennesseeGirl

Had very bad reaction to that stuff.
Called my pharmacist and she told me to stop taking it immediately. and that was 5 years ago.


3 posted on 03/20/2010 4:56:59 PM PDT by Marty62 ( Marty60)
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To: TennesseeGirl

I have three months to balance out those numbers. Might now take it anyway. Neurotoxins. Wow. Who knew.


4 posted on 03/20/2010 5:03:27 PM PDT by Mercat
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To: Marty62

Tried Zocor, Lipitor, Mecocor and had leg cramps. Had to quit all.

Then after having a quintuplet bypass, I have to have something.

So far 8 months on Crestor is okay and numbers are fine.

I still hate taking any medicine though. But what the hay, not
that many years left anyway.


5 posted on 03/20/2010 5:03:49 PM PDT by TribalPrincess2U (demonicRATS... taxes, pain and slow death. Is this what you want?)
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To: TennesseeGirl

80mg is a very high dose. I was on 40 at a high and now 20. Numbers good.


6 posted on 03/20/2010 5:05:23 PM PDT by conservaDave (You can't ignore the democRAT...He's a menace to health, home and industry...kill him!)
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To: TennesseeGirl
Statins cause the liver to quit/slow the production of cholesterol, but also cause the liver to quit/slow the production of something vital to heart health.More and more reaearch is showing no correlation to statins and prevention of strokes and heart attacks.

Part D of Medicare would be totally solvent if it refused to pay for statins, which it should do.I guarantee about 80% of Medicare patients take statins.

vaudine

7 posted on 03/20/2010 5:05:24 PM PDT by vaudine
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To: TennesseeGirl

Hope all of you taking statins are taking CoQ10! Also, up your Vit D3 to 5000iu a day! Unless, of course you spend 1/2 hour a day almost naked in the mid day sun!


8 posted on 03/20/2010 5:06:51 PM PDT by goodnesswins (Tagline, oh, tagline, whereart thou tagline....)
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To: TennesseeGirl

I’m on Lipitor which does not have a generic but my insurer for pharmacy prescriptions, Medco, has been pushing me to switch to a generic for Zocor for two years now for the cost savings. Lipitor has been doing the trick well for several years now so I won’t change and this gives me even more reason not to. Eventually, a generic will come out for Lipitor and I’ll switch to a generic then.


9 posted on 03/20/2010 5:06:54 PM PDT by OrangeHoof ("Barack Obama" is Swahili for "Bend over suckahs".)
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To: Mercat

most people can handle the neurotoxins of most statin drugs...I cant.


10 posted on 03/20/2010 5:07:43 PM PDT by Vaquero (BHO....'The Pretenda from Kenya')
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To: TribalPrincess2U

Oh and that quintuplet bypass...I probably wouldn’t have gotten it under 0Care
and a pill wouldn’t have helped me.


11 posted on 03/20/2010 5:08:09 PM PDT by TribalPrincess2U (demonicRATS... taxes, pain and slow death. Is this what you want?)
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To: TennesseeGirl

Yep....check out what the Space Doc has to say about statins also....http://spacedoc.net/


12 posted on 03/20/2010 5:08:14 PM PDT by HomersNose
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To: TribalPrincess2U

Took a blood pressure med that caused horrific leg cramps and shortness of breath along with weight gain and a nasty cough.

I’ll take my changes without their help, thank you.


13 posted on 03/20/2010 5:10:31 PM PDT by Carley (Are you better off now than one year ago? HELL NO!!!!!)
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To: TennesseeGirl
Been taking since 1980 and chol is 125. Already had 16 angioplasty's. Wish they had them avail when I was 18. Such is life. Still active and happy. 67 yo.

This is the FDA trying to help ObamGoof's healthreform. Like NYC trying to ban salt.

Semper Fi!

14 posted on 03/20/2010 5:11:01 PM PDT by Pit1
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To: vaudine

I told my doc I’d rather die of a heart attack than liver cancer.

He was not amused.


15 posted on 03/20/2010 5:11:18 PM PDT by Carley (Are you better off now than one year ago? HELL NO!!!!!)
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To: Carley

Ooops. Take my CHANCES


16 posted on 03/20/2010 5:12:06 PM PDT by Carley (Are you better off now than one year ago? HELL NO!!!!!)
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To: TennesseeGirl
My doctor wanted to put me on Statins because my LDL was 112. For many years if you were under 130 everything was OK. Then all of a sudden the recommended level was dropped to 100. Think of all the millions between 100-130. That's a lot of prescriptions. With diet and exercise I lowered it to 104 and he finally stopped bugging me about it.

I cannot believe how fast he wanted to put me on these drugs. Has anyone had a similar experience?
17 posted on 03/20/2010 5:12:08 PM PDT by truthguy (Good intentions are not enough!)
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To: TennesseeGirl
I'm on an 80 mg. dose of Pravachol, and get weird muscle aches, too. Chalked it up to being on the downhill side of 50 while still trying to do things like I was 20, but now I think I'm going to have a little talk with my doc at my next checkup. Seem to be getting more lethargic, too. I chalked that up to marriage , but it's only been since I was put on cholesterol meds several months ago.


18 posted on 03/20/2010 5:13:05 PM PDT by Viking2002 (Old fishermen never die. They just smell that way.)
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To: goodnesswins

I will ask my cardio about CoQ10 and VitD3. Don’t get much sun.


19 posted on 03/20/2010 5:13:08 PM PDT by TribalPrincess2U (demonicRATS... taxes, pain and slow death. Is this what you want?)
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To: Carley

My brother died of liver cancer—actually spread to his liver from his colon.

Take the heart attack.

(also,wife and I were prescribed Vitorin—a statin. That lasted less than a week. Both woke up with leg cramps each morning, something that never happened before—we told the Doc—ixnay on the drugs.


20 posted on 03/20/2010 5:16:18 PM PDT by exit82 (Democrats are the enemy of freedom. Sarah Palin is our Esther.)
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To: Carley

I thought so also, but unfortunately, it doesn’t always happen that way.

They can keep tabs on your liver and such with 6 months or yearly test.
Any problems can be caught if you have these done.

Under 0Care I doubt that tests will continue.

But, I don’t know what he has in store. Just a guess.


21 posted on 03/20/2010 5:16:33 PM PDT by TribalPrincess2U (demonicRATS... taxes, pain and slow death. Is this what you want?)
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To: TribalPrincess2U

Don’t say that!

I have been taking Lipitor for years. If I don’t my #s hit 600. Yeah I know. I have to have tests ever 4 months. It is amazing how one test off of Lipitor is so high and 4 months later on Lipitor they are in the very low 200s.
Haven’t tried crestor. afraid to NOT take Lip.

Be well and happy.


22 posted on 03/20/2010 5:17:01 PM PDT by Marty62 ( Marty60)
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To: truthguy

My doc gave me three months to lower it. Its at 144. My HDL is too low. He also said to take vitamin D - 1000/day.


23 posted on 03/20/2010 5:17:23 PM PDT by Mercat
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To: Viking2002

YES, tell your doctor about anything unusual. Cramps, pain, etc. Anything different. You can be in charge. Ask to try something else. I did.


24 posted on 03/20/2010 5:20:46 PM PDT by TribalPrincess2U (demonicRATS... taxes, pain and slow death. Is this what you want?)
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To: TennesseeGirl

All statins have the same side effects, that is why I don’t take them.


25 posted on 03/20/2010 5:22:53 PM PDT by calex59
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To: TennesseeGirl
FTR:

Total Cholesterol= LDL + HDL + (Triglycerides ÷ 5)
26 posted on 03/20/2010 5:26:26 PM PDT by truthguy (Good intentions are not enough!)
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To: Carley
"I told my doc I’d rather die of a heart attack than liver cancer.

He was not amused."

Mine wasn't either; doing fine on diet(old fashioned oats), exercise and not worrying about it. It the sweet by and by I'll be there...

27 posted on 03/20/2010 5:27:37 PM PDT by Dust in the Wind (U S Troops Rock)
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To: Marty62

Not saying the others are not good. Just find the one that fits you.

They put me on Crestor after the operation. It was not a generic.
I asked what the difference was between Crestor and the others.

He said Crestor was more up to date and worked more efficiently.
Not in those exact words. That convinced me to stay on it awhile
and pay the cost. My diabetic husband has done great on Zocor.


28 posted on 03/20/2010 5:29:09 PM PDT by TribalPrincess2U (demonicRATS... taxes, pain and slow death. Is this what you want?)
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To: Dust in the Wind

Oatmeal, walking, watching my diet. Good multi viatimins, etc.

Keeping a good attitude altho since the maoist was elected it’s been hard to keep the stress levels down.


29 posted on 03/20/2010 5:29:38 PM PDT by Carley (Are you better off now than one year ago? HELL NO!!!!!)
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To: TennesseeGirl

This is old news, folks. They’re talking about rhabdomyolysis, which is where your muscles can begin to breakdown, ache, and cause renal failure. It’s pretty rare.

If you’re on a lot of meds, it might be a wise move to consider crestor (rosuvastatin). It’s the cleanest of the statins with the fewest interactions with other meds.


30 posted on 03/20/2010 5:36:09 PM PDT by CaspersGh0sts
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To: TribalPrincess2U

Yep ever individual is different. What works for one may not be right for another.


31 posted on 03/20/2010 5:37:16 PM PDT by Marty62 ( Marty60)
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To: Carley
...since the maoist was elected it’s been hard to keep the stress levels down.

Yes, this horrible man is starting to effect my health as well. The stress that he is inducing in millions is doing as much damage to the health of the public as his health care plans. I'm not going to let this POS affect my stress levels. I've joined a stress management program at work and in a workshop I expressed my feelings about this. Turns out I wasn't the only one. Some were offended. F'em. I'm tired of people being offended and trying to modify everything I say not to offend. If they don't like it TFB. There, that lowered my stress level!
32 posted on 03/20/2010 5:39:44 PM PDT by truthguy (Good intentions are not enough!)
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To: TribalPrincess2U

You can get peripheral neuropathy from statin drugs....


33 posted on 03/20/2010 5:39:56 PM PDT by Vaquero (BHO....'The Pretenda from Kenya')
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To: TennesseeGirl

I took this stuff and my muscles were SOOOOO sore. We switched to Crestor.


34 posted on 03/20/2010 5:41:07 PM PDT by bolobaby
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To: CaspersGh0sts

I have a dear Aunt who was just recently diagnosed with rhabdomyolysis, she had been on Lipitor for less than a year. Her symptoms started out as leg cramps and dizziness, and was wrongly diagnosed w/ restless leg syndrome. She has always been a very energetic, hard worker, but she has been unable to even drive herself for the past few weeks...and will probably never recover fully.


35 posted on 03/20/2010 5:46:41 PM PDT by Larightgirl (get rich quick....count your blessings!)
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To: TribalPrincess2U
I read a lot of alternative med. docs. Finally decided on Dr. Julian Whitaker's vitamin/minerals and his COQ10. He is an MD who practiced standard med. for some time but did not like that drs. were/are being taught to just write a prescription for every new sysptom. He felt some very good alternative treatments that have been proven had been tossed.He has had a Wellness Clinic in Newport Beach, CA for 30 years and has developed his own supplements. I recently mentioned we had started taking Dr. Whitaker's supplements, and a neuro surgeon's wife sitting at the table said her mother started taking his Eye Essentials and they reduced her cataracts to the point her opthalmologist was amazed.--unsolicited commercial I welcomed.

Whitaker and several others warn that although everything listed on the bottle may very well be in the tablet/capsule, it is not necessarily getting into you system at full dose because of shortcuts used in either the raw products or the delivery process. COQ10 is one esp. to watch. Several have said COQ10 with Ubiquinol in a jell cap goes directly to cellular level and is utilized in full strength. Another to watch is E--be sure it has d-alpha (natural) instead of dl-alpha (synthetic). My husband's brother-in-law had all the by-passes he could have several years ago. He has been told there is nothing else to do for him--his hesrt is shot; his lungs are shot; and now his liver is going. He takes an awful number of pills including a heavy statin. His drs have not even told him to take fish oil and a vitamin. My husband's cardiologist believes in vitamins and esp. fish oil.

They tried statins on me and my husband. We both got leg cramps and he also had nose bleed often. We just told our doc we aren't taking them.

vaudine

36 posted on 03/20/2010 5:50:49 PM PDT by vaudine
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To: nnn0jeh

pi


37 posted on 03/20/2010 5:52:16 PM PDT by kalee (The offences we give, we write in the dust; Those we take, we engrave in marble. J Huett 1658)
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To: kalee; nnn0jeh

Where did the ng go? LOL

Ping


38 posted on 03/20/2010 5:53:10 PM PDT by kalee (The offences we give, we write in the dust; Those we take, we engrave in marble. J Huett 1658)
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To: Excellence

self-ping.


39 posted on 03/20/2010 5:55:18 PM PDT by Excellence (Meet your new mother-in-law, the United States Government.)
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To: truthguy

I make it a point to express my dismay at the direction he’s taking this country and not a single person has disagreed.

One person did say that all this unemployment is Bush’s fault, but she’s a member of the NEA and can’t help herself. So brainwashed, poor thing.


40 posted on 03/20/2010 5:56:13 PM PDT by Carley (Are you better off now than one year ago? HELL NO!!!!!)
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To: CaspersGh0sts
This is old news, folks. They’re talking about rhabdomyolysis, which is where your muscles can begin to breakdown, ache, and cause renal failure. It’s pretty rare.

Yep. The various heart publications indicate that if you're going to have problems, they normally will happen in the first few months.

Since 1995 I have taken high doses of Lipitor followed by simvastatin 80mg. I had 6 coronary bypasses in 1981 and now, 29 years later, the bypasses are still open. Liver and kidney functions have been normal, checked regularly. Haven't had muscle problems in that time so I'm not likely to be scared off quickly.

41 posted on 03/20/2010 5:59:06 PM PDT by Ole Okie
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To: vaudine

Nose bleeds? Now that’s something different.

If you can’t, you can’t. I’m afraid not to take them
now after not taking them before my operation.

I don’t want more by-passes or what I fear the most...stroke.


42 posted on 03/20/2010 5:59:46 PM PDT by TribalPrincess2U (demonicRATS... taxes, pain and slow death. Is this what you want?)
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To: Carley

Sounds like you were taking lisinopril. Maybe you see try a ARBS (Angiotensin II receptor blockers ).

T. Package RN


43 posted on 03/20/2010 6:02:12 PM PDT by Total Package (TOLEDO, OHIO THE MRSA INFECTION IN THE STATE and the death of freedom)
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To: conservaDave
80mg is a very high dose. I was on 40 at a high and now 20. Numbers good.

I agree. I'm on 20 mg. Simvastatin with 10 mg. Zetia and have great numbers with no ill effects in over a year.

44 posted on 03/20/2010 6:04:34 PM PDT by Bernard Marx (I don’t trust the reasoning of anyone who writes then when they mean than.)
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To: Total Package

Yup, the notorious lisinopril. Oh that kennel cough was something else.


45 posted on 03/20/2010 6:05:01 PM PDT by Carley (Are you better off now than one year ago? HELL NO!!!!!)
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To: TribalPrincess2U
Red Yeast Rice has the same properties as the statin drugs but without the adverse reactions. Drug companies have been pushing to get it off the market...does that tell you something?

Read up on it...it may be something of interest.

46 posted on 03/20/2010 6:08:19 PM PDT by A_Tradition_Continues (formerly known as Politicalwit ...05/28/98 Class of '98...PROCESS MATTERS)
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To: conservaDave

80mg is a very high dose. I was on 40 at a high and now 20. Numbers good.

***

I’m on 40 mg - have noticed shaking in left hand recently. Numbers have been stable for 2+ yeasr now, about 155-165 total cholesterol.

Was wondering if I could decrease ...


47 posted on 03/20/2010 6:12:05 PM PDT by Lmo56
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To: Vaquero

I give up, what’s peripheral, etc
?


48 posted on 03/20/2010 6:15:38 PM PDT by brivette (paper)
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To: truthguy
I've been off statins (poison) for over 3 years. Once I found out that this whole "cholesterol Problem" was/is a huge sham, and learned about the side-effects (that I was experiencing for years but didn't know any better), I told my doc that I wasn't going to take any of them anymore. He didn't argue much. Seriously, anyone that has been taking them and has any concerns, do a little research.

In short:

- "target" levels were established to ensure enough of the population would fall "at risk" (even been adjusted lower to get more users over time)

- the statins cross the blood-brain barrier and kill off cholesterol in the brain that is not easily replenishable (BTW, the body, esp. the brain NEEDs cholesterol to function and grow!)

- I went and had one of the cardiac scoring high-tech MRIs that you have to pay for out of pocket (most ins. don't cover) and found out that I have way less than 10% scaling, which based on my age, is quite good (it is actually the scaling or calcification in the arteries that is a cause of heart disease, not a high cholesterol level!)

- all of the studies that they have done over the years can only establish a very weak (almost non-existent) relationship between the use of statins and lower instances of heart disease

Obviously everyone should do their own research (i.e., not rely on an AMA member) and make their own decision. I have felt so much better since I stopped and have had all of those nasty side effects disappear over time.

49 posted on 03/20/2010 6:16:54 PM PDT by zzeeman (Fighting to not be the amongst the last generation to enjoy freedom & liberty!)
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To: TribalPrincess2U
My husband had 4 bypasses a year ago. He couldn't take most of the medicines they put him on. They took him off amioderone)spelling?), and a couple others He takes blood thinner for atrial flutter and the smallest dose possible of a beta blocker (coreg). He is 82, and I am glad he had the operation before the possibiity of Obamacare. He is doing well.

Iunderstand your fear. Most people feel the same as you--afraid not to because the dr. prescribes; just read everything you can about statins. If you haven't subscribed to Newsmax, do so and you will get bulletins on health news. Between the fact that the normal high for cholesterol as well as LDL, triglicerides, etc. were lowered drastically a couple decades ago, and the huge side effects listed for statins, plus the 2 or 3 huge research programs that have been terminated early because the statin group were having many more strokes and heart attacks tha the placebo group--I am much more afraid to take them than not.

vaudine

50 posted on 03/20/2010 6:18:38 PM PDT by vaudine
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