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Harvard scientists reverse the ageing process in mice now for humans
The Guardian ^ | Nov 28, 2010 | Ian Sample

Posted on 11/29/2010 9:18:29 PM PST by djf

Harvard scientists were surprised that they saw a dramatic reversal, not just a slowing down, of the ageing in mice. Now they believe they might be able to regenerate human organs Scientists claim to be a step closer to reversing the ageing process after rejuvenating worn out organs in elderly mice. The experimental treatment developed by researchers at the Dana-Farber Cancer Institute, Harvard Medical School, turned weak and feeble old mice into healthy animals by regenerating their aged bodies. The surprise recovery of the animals has raised hopes among scientists that it may be possible to achieve a similar feat in humans – or at least to slow down the ageing process.

(Excerpt) Read more at guardian.co.uk ...


TOPICS: Culture/Society; Miscellaneous; News/Current Events
KEYWORDS: aging; humans; mice; mouse
I know I have shared with a few FReepers my essay "The Geezer Within" that focuses on the changes and causes of aging. A prominent part of that essay was the breakdown of the telomeres. There are a number of well known studies that have shown aging can indeed be slowed down. But this is different. Very different!
1 posted on 11/29/2010 9:18:31 PM PST by djf
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To: neverdem

Ping...


2 posted on 11/29/2010 9:19:09 PM PST by djf (Touch my junk and I'll break yur mug!!!)
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To: djf

Good lord... Don’t let CONGRESS get a hold of it!

We’d be stuck with some old dems much longer than we care for.


3 posted on 11/29/2010 9:22:48 PM PST by cableguymn
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To: djf

Good lord... Don’t let CONGRESS get a hold of it!

We’d be stuck with some old dems much longer than we care for.


4 posted on 11/29/2010 9:23:03 PM PST by cableguymn
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To: cableguymn

Helen Thomas is up in Cambridge camped out a hotel waiting her turn for treatment.


5 posted on 11/29/2010 9:41:23 PM PST by Oldexpat
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To: cableguymn

Helen Thomas is up in Cambridge camped out a hotel waiting her turn for treatment.


6 posted on 11/29/2010 9:41:35 PM PST by Oldexpat
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To: Oldexpat

7 posted on 11/29/2010 9:45:01 PM PST by FromLori (FromLori)
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To: djf

bookmark


8 posted on 11/29/2010 9:46:08 PM PST by GOP Poet (Obama is an OLYMPIC failure.)
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To: djf

bookmark


9 posted on 11/29/2010 9:46:14 PM PST by GOP Poet (Obama is an OLYMPIC failure.)
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To: Oldexpat

They said mice, they didn’t say rats.


10 posted on 11/29/2010 9:48:10 PM PST by Titus-Maximus (Light from Light)
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To: djf

bump: I don’t want to look like willie nelson or dr laura


11 posted on 11/29/2010 9:51:40 PM PST by Taffini ( Mr. Pippen and Mr. Waffles do not approve and neither do I)
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To: cableguymn

I for one am fascinated by this.


12 posted on 11/29/2010 9:51:58 PM PST by ZAROVE
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To: cableguymn
“Good lord... Don’t let CONGRESS get a hold of it!

We’d be stuck with some old dems much longer than we care for.”

...Too Funny!

13 posted on 11/29/2010 9:56:27 PM PST by b cool
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To: ZAROVE

I’m not totally convinced that the protocols they used are indicating what they think they are indicating.
It may be that all this does is let a normally accelerated-aging mouse live out what would be his normal lifespan, rather than a premature death.

I need to see the abstracts and find out more about the therapies.

All my cynicism aside...
it could be the fountain of youth.

Anybody else think this story might just go away and we never hear of it again?


14 posted on 11/29/2010 10:02:28 PM PST by djf (Touch my junk and I'll break yur mug!!!)
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To: djf

btt


15 posted on 11/29/2010 10:05:54 PM PST by Cacique (quos Deus vult perdere, prius dementat ( Islamia Delenda Est ))
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To: cableguymn

Good Lord, don’t let Brett Favre get ahold of it! We’d be stuck with his fake retirements and season-ending interceptions much longer than we care for.


16 posted on 11/29/2010 10:06:08 PM PST by Strk321
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To: djf

The abstract is linked in the story.

And to your question about this story going away and never hearing it again, I don’t think so. There are many new studies about the aging process which are along this same line. Some are showing free radicals hitting the DNA up to 10,000 times per hour. If that’s true then the new cell formed will be a degraded or an aged cell. So, stopping that damage will lead to a new cell with less aging properties.

Unanswered is whether elimination of intrinsic instigators driving age-associated degeneration can reverse, as opposed to simply arrest, various afflictions of the aged.


17 posted on 11/29/2010 10:16:23 PM PST by Balata
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To: djf
reverse the ageing process

Is this really a good thing? What happens when one gets to 0?

"Paging Mr. Button. Mr. Benjamin Button. Please pick up the white courtesy phone..."

18 posted on 11/29/2010 10:17:16 PM PST by Onelifetogive (I tweet, too...)
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To: djf

A person should read the entire article before getting their hopes up.


19 posted on 11/29/2010 10:24:06 PM PST by Moonman62 (Half of all Americans are above average.)
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To: djf

Video - Regrowing Body Parts

http://www.youtube.com/watch?v=L4_Um5VB2H0


20 posted on 11/29/2010 10:33:00 PM PST by preacher (A government which robs from Peter to pay Paul will always have the support of Paul.)
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To: preacher

Thnx.
I had seen some vid reports about using extracellular matrix sheets to grow a new bladder for a woman who had bladder cancer.
Alot of interesting stuff going on.


21 posted on 11/29/2010 10:42:36 PM PST by djf (Touch my junk and I'll break yur mug!!!)
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To: djf

Of course the moral dillema is... should we? What happens when the boomers go on living “forever” and the earth is stuffed with more generations alive at the same time draining the earth’s resources.

If it is just a matter of living one’s natural life span with less disease and degeneration, well that could be another matter.


22 posted on 11/29/2010 10:42:39 PM PST by marsh2
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To: marsh2

One hell of a state lottery game, eh?

Match 8 numbers and LIVE FOREVER!!!!


23 posted on 11/29/2010 10:45:44 PM PST by djf (Touch my junk and I'll break yur mug!!!)
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To: marsh2

“If it is just a matter of living one’s natural life span with less disease and degeneration, well that could be another matter.”

No one’s talking about living forever. A normal lifespan (to one’s 80s or 90s) is fine if you could be healthy and active to the end.

Some people just happen to be genetically hardier than others. Ronald Reagan was 69 when he became president, but he didn’t have gray hair until after he was out of office. When he had surgery to remove a colon growth in 1985, the doctors noted that his organs were like those of a man at least 20 years younger (or so I read). He also had a very healthy for his age blood pressure reading of 140. Of course, we all know about the Alzheimer’s in his last years, but he still lived to 92.

And somehow Keith Richards is still alive despite the awesome quantities of drugs he’s consumed in his day.


24 posted on 11/29/2010 11:10:15 PM PST by Strk321
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To: djf

We are on the brink of a brave new world...


25 posted on 11/29/2010 11:40:23 PM PST by BigCinBigD (Northern flags in South winds flutter...)
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To: djf

They covered this on ABC Nightly news this evening and when the researcher being interviewed said “it restores fertility”, I really thought I would laugh myself silly. What are we Senior Saints gonna do with ‘restored fertility’? It just hit me the wrong way, I guess.


26 posted on 11/29/2010 11:59:44 PM PST by grame (May you know more of the love of God Almighty this day!)
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To: djf

...


27 posted on 11/30/2010 12:18:44 AM PST by maine-iac7 (We Stand Together of We Fall Apart)
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To: djf

I dunno, I don’t think I want to be 13 again ;-)


28 posted on 11/30/2010 2:54:20 AM PST by vanilla swirl (We are the Patrick Henry we have been waiting for!)
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To: djf

They should use Helen Thomas and Hillary C. as test subjects. If it works on them is will work on anybody.


29 posted on 11/30/2010 4:01:42 AM PST by chainsaw ( 'You know that your landing gear is up and locked when it takes full power to taxi to the terminal)
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To: preacher
Video - Regrowing Body Parts

That's pretty cool. I can see someone with severe arthritis having their hands amputated then in a few months having new ones.

30 posted on 11/30/2010 4:11:25 AM PST by TangoLimaSierra (To the left the truth looks Right-Wing.)
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To: djf

Yea, and I saw a woman once that used wasp jelly on her skin to make her look younger and she turned into a monster that killed people. I think that woman was a Harvard researcher too....


31 posted on 11/30/2010 5:16:51 AM PST by vetvetdoug
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To: djf

Great! Just what we need. Mice that live longer.


32 posted on 11/30/2010 5:46:29 AM PST by UCANSEE2 (Lame and ill-informed post)
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To: djf
Anybody else think this story might just go away and we never hear of it again?

Hasn't gone away for thousands of years.

33 posted on 11/30/2010 5:48:18 AM PST by UCANSEE2 (Lame and ill-informed post)
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To: djf

The older I get, the more interested I am in stuff like this. :-)

On the other hand, my ideological side says that we can’t allow people to live forever, it will be the end of our way of life.


34 posted on 11/30/2010 11:16:22 AM PST by CharlesWayneCT
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To: CharlesWayneCT

Well, nothing would guarantee that you would live forever. There will always be disease, accidents, wars, etc.

In fact it sounds like they haven’t yet been able to prove that it makes anybody live longer. It will take many detailed studies of cellular biology, hormone levels, energy and diets, etc to determine if this is actually turning back the clock and setting things up for a long (perhaps VERY long) lifespan.

But even if it means that a person who lives till they are 87, but in a ravaged and debilitating state could then live to 87, but do it in a body that’s like in their forties, that would be a good thing.

U seriously doubt you will ever be able to go into the local Rite-Aid and buy pills OTC that do this sort of thing.


35 posted on 11/30/2010 11:44:28 AM PST by djf (Touch my junk and I'll break yur mug!!!)
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To: CharlesWayneCT

Typo.
I seriously doubt, not U seriously doubt.


36 posted on 11/30/2010 11:45:27 AM PST by djf (Touch my junk and I'll break yur mug!!!)
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To: djf
This is sure to turn out well...


Frowning takes 68 muscles.
Smiling takes 6.
Pulling this trigger takes 2.
I'm lazy.

37 posted on 11/30/2010 12:23:40 PM PST by The Comedian (Government: Saving people from freedom since time immemorial.)
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To: djf

This is exciting and frightening at the same time, retirement would be an obsolete concept, some of the worst dictators and tyrants around would be immortal.


38 posted on 11/30/2010 12:33:20 PM PST by Brett66 (Where government advances, and it advances relentlessly , freedom is imperiled -Janice Rogers Brown)
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