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New Link in Tinnitus Research
insciences.org ^ | 05-03-2011 | Source: The University of Western Australia

Posted on 05/04/2011 7:38:19 AM PDT by Red Badger

Researchers at The University of Western Australia have shown changes in a part of the brain previously not known to be involved in tinnitus generation.

The nerve cell types and the chemistry of the neural circuitry in this part of the brain differ subtly from those other parts of the brain previously thought to be involved. This means the results published in The Journal of Neuroscience could be potentially important for the future development of drug treatments.

Tinnitus is a potentially debilitating disorder of hearing which is characterised by the perception of non-existent sounds, usually roaring, hissing or ringing in the ears.

The changes in the brain that cause tinnitus are poorly understood. It is clear however that alterations in nerve cell electrical behaviour must underlie the abnormal "phantom" perception of sound that is experienced by tinnitus sufferers.

For many years, the exact site in the brain where this abnormal nerve cell behaviour occurs has been a contentious issue.

The research, performed by student Darryl Vogler, Professor Donald Robertson and Associate Professor Wilhelmina Mulders, has developed a reliable animal model which can induce tinnitus and also measure brain cell activity.

"This is an important step toward further research in this area," Associate Professor Mulders said.

"If we can establish a direct link between this increased brain cell activity and tinnitus we may be able to move a step closer to finding a way to treat tinnitus."

The paper titled Hyperactivity in the Ventral Cochlear Nucleus after Cochlear Trauma concludes that hyperactivity in this part of the brainstem therefore needs to be considered in relation to further neural research into tinnitus.

Contact: Janine MacDonald, UWA Public Affairs, Tel: (+61 8) 6488 5563, Email: janine.macdonald@uwa.edu.au

Source: The University of Western Australia


TOPICS: Australia/New Zealand; Business/Economy; Culture/Society; United Kingdom
KEYWORDS: ear; health; hearing; tinnitus
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If you want ON or OFF the Tinnitus Ring List just Ring me up!...........

1 posted on 05/04/2011 7:38:23 AM PDT by Red Badger
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To: joe fonebone; SamiGirl; gitmogrunt; Freee-dame; ROCKLOBSTER; ryderann; Red_Devil 232; ...

Ring!.........


2 posted on 05/04/2011 7:38:58 AM PDT by Red Badger (Mitt Romney: The Harold Stassen of the 21st century........)
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To: Red Badger

Doesn’t sound like phantom noise to me.


3 posted on 05/04/2011 7:42:50 AM PDT by LauraJean (sometimes I win sometimes I donate to the equine benevolent society)
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To: Red Badger

How do they know when an animal test subject has tinnitus?


4 posted on 05/04/2011 7:48:27 AM PDT by FReepaholic (Land of the free my @ss)
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To: LauraJean

Sounds like the high pitched sound given off by the old TV sets when they were turned on.


5 posted on 05/04/2011 7:56:34 AM PDT by PetroniusMaximus
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To: LauraJean

Me neither, I’ve got it bad but just in my left ear.


6 posted on 05/04/2011 7:57:37 AM PDT by far sider
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To: Red Badger

Badge! Definitely put me on your ping list! I have it,,, terribly! People think I’m deaf. I’m not! It’s just that the tinnitus is louder than people speak!


7 posted on 05/04/2011 7:58:33 AM PDT by Dr. Bogus Pachysandra ( Ya can't pick up a turd by the clean end!)
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To: Red Badger

I had a case of tinitus about five years ago. Popped out of nowhere and bugged me for several years. At first, being unaware of tinitus, I wandered around the house trying to find the source of the sound for several hours. I even walked outside, thinking it might be coming from a neighbors home. I finally realized it was all in my head. lol

It took a handful of years for the buzzing to go away finally. Doctor never found a cause and we chalked it up to severe stress.


8 posted on 05/04/2011 8:02:59 AM PDT by catbertz
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To: PetroniusMaximus

When I was about 5-7 (some time ago I admit)I could tell who had their tvs on as I rode my bicycle down the road past their houses. I would get a ringing in my ears if it was on. I don’t get it from the tvs anymore - I imagine it was related to the tube sets. But periodically I still get the ring come up for no apparent reason - I’m always looking for a source when that happens, but haven’t been able to correlate it yet. I’m hoping it isn’t just tinnitus developing over time.


9 posted on 05/04/2011 8:08:29 AM PDT by reed13
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To: catbertz

I had tinnitus and inner ear problems for about ten years. The tinnitus was mild (coming and going) but the dizziness could really get me at times. I had to place the palms of my hands flat on the mattress to stop the “spins” at night when I slept.

One day I took some Brewer’s yeast, and I felt SO much better - in a lot of ways. So I painstakingly went through all the ingredients in trials, to find out what was helping me. Turned out to be Chromium.

Since I’ve been taking chromium it’s been rare I’ve had a problem. It came back when I had anemia, and when I took a little too much aspirin. A lot of things can cause it. But for me, chromium was the answer.


10 posted on 05/04/2011 8:13:11 AM PDT by I still care (I miss my friends, bagels, and the NYC skyline - but not the taxes. I love the South.)
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To: FReepaholic

You catch him dancing when there isn’t any music.


11 posted on 05/04/2011 8:23:59 AM PDT by Portcall24
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To: Red Badger

Please add me to your list. Thanks!


12 posted on 05/04/2011 8:24:14 AM PDT by Abigail Adams
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To: FReepaholic

You catch him dancing when there isn’t any music.


13 posted on 05/04/2011 8:25:16 AM PDT by Portcall24
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To: LauraJean

I have the ‘crickets’ type...I’ve always been an out doors guy so it doesn’t bother me too much.

RESULTS: Patients with tinnitus and NIHL exhibited vitamin B12 deficiency in 47% of cases (blood levels < or = 250 pg/mL). This was significantly more (P < .023) compared with NIHL and normal subjects who exhibited vitamin B12 deficiency in 27% and 19%, respectively.

http://www.ncbi.nlm.nih.gov/pubmed/8484483


14 posted on 05/04/2011 8:25:26 AM PDT by Bulwinkle (Alec, a.k.a. Daffy Duck)
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To: PetroniusMaximus

Add to it the sound of the old fluorescent light ballasts going bad and you’ve got it.


15 posted on 05/04/2011 8:26:13 AM PDT by FourPeas
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To: I still care

Thanks for your post. I’ll give it a try.


16 posted on 05/04/2011 8:29:14 AM PDT by pingman (You can lead a liberal to logic, but you can't make them think.)
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To: Dr. Bogus Pachysandra
It’s just that the tinnitus is louder than people speak!

I think I'm finally at that point. Hearing loss runs in my family, so I knew someday I'd likely need hearing assistance. Ugh.

17 posted on 05/04/2011 8:31:35 AM PDT by FourPeas
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To: FReepaholic

“How do they know when an animal test subject has tinnitus?”

An excellent question indeed.


18 posted on 05/04/2011 8:37:07 AM PDT by Gatún(CraigIsaMangoTreeLawyer)
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To: LauraJean

I wish those phantoms would hold it down a bit!


19 posted on 05/04/2011 8:39:34 AM PDT by The_Media_never_lie
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To: FReepaholic

How do they know when an animal test subject has tinnitus?

They look at the eyes..............

20 posted on 05/04/2011 8:39:51 AM PDT by Red Badger (Mitt Romney: The Harold Stassen of the 21st century........)
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To: reed13

“When I was about 5-7 (some time ago I admit)I could tell who had their tvs on as I rode my bicycle down the road past their houses.”

That was not tinnitus, it was your ability, as a youngster, to hear very high frequency sound. I could hear the ultrasonic burglar alarms at art museums.

After years of shooting now it sounds like a missile is about to smack me. I might add many drugs, aspirin in particular, will cause, or make worse, ringing in the ears.


21 posted on 05/04/2011 8:41:36 AM PDT by TxDas (This above all, to thine ownself be true.)
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To: Red Badger

Add me please.

Thank you.


22 posted on 05/04/2011 8:45:36 AM PDT by Gatún(CraigIsaMangoTreeLawyer)
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To: I still care
Since I’ve been taking chromium it’s been rare I’ve had a problem. It came back when I had anemia, and when I took a little too much aspirin. A lot of things can cause it. But for me, chromium was the answer.

How does one take Chromium? As a pill form, or dietary supplement? Also, your mention of aspirin intrigues me, because I have been taking a low-dose form of aspirin daily for years now. I have had a constant high-pitch ringing in both ears for years.
23 posted on 05/04/2011 8:47:10 AM PDT by AaronInCarolina
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To: Red Badger

Please, add me to the tinnitus ring list.


24 posted on 05/04/2011 8:47:34 AM PDT by doubled (I didn't say it was your fault, I said I was going to blame you.)
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To: Red Badger

Please add me to your list.

I know mine gets worse when I take too much aspirin or tylenol. Mine is the crickets type, so I am still pretty able to hear everything. I used to be able to hear ultrasonic alarms in stores, though!


25 posted on 05/04/2011 8:48:27 AM PDT by Grammy
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To: PetroniusMaximus

“Sounds like the high pitched sound given off by the old TV sets when they were turned on.”

That is the best description of what it sounds like that I have heard.


26 posted on 05/04/2011 8:48:35 AM PDT by HereInTheHeartland (Yes We Can, have smaller government)
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To: Red Badger

Ring


27 posted on 05/04/2011 8:50:19 AM PDT by AaronInCarolina
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To: PetroniusMaximus

I have had it always. Didnt even realize what silence was until I talked about it when I was 12 or 13. I thought everyone had the TV noise in their head.


28 posted on 05/04/2011 8:50:56 AM PDT by Vermont Lt (How long before the Mall becomes Tahifir Sq?)
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To: Red Badger
The offender of my ears ringing that drove a 1/2 stack of 12" cones:


29 posted on 05/04/2011 8:56:19 AM PDT by Rebelbase
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To: I still care

“I had to place the palms of my hands flat on the mattress to stop the “spins” at night when I slept.”

I have had tinnitus for awhile now. I had the spinning thing come up suddenly and it was pretty bad. Went to the ENT doctor for the first time. Had been going to go for the tinnitus even though I assumed there isn’t much they can do.
They did a CAT scan just to be sure there was nothing there that shouldn’t be. (or to make a boat payment!)

Didn’t find anything. Doc recommended Lipo-flavonoid. I don’t think it’s helping.

Maybe I’ll try the Chromium?


30 posted on 05/04/2011 8:56:29 AM PDT by HereInTheHeartland (Yes We Can, have smaller government)
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To: Red Badger

Put me on the Tinnitus Ring List. I have a hard time reading long articles but if it helps find more quiet I will force myself.

Thanks


31 posted on 05/04/2011 8:57:19 AM PDT by mountainlion (America land of the free because of the Brave.)
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To: Red Badger

Might give the Chromium a shot.


32 posted on 05/04/2011 9:06:54 AM PDT by gitmogrunt
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To: Rebelbase

I play pedal steel. Always had to sit in front, and to the side of the drummer. Ride and crash cymbals always in one ear or the other. Of course the Redhawk 44 mag didn’t help either! Wore plugs when at the range, but not when hunting.


33 posted on 05/04/2011 9:08:25 AM PDT by Dr. Bogus Pachysandra ( Ya can't pick up a turd by the clean end!)
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To: Red Badger

LOL!


34 posted on 05/04/2011 9:18:32 AM PDT by FReepaholic (Land of the free my @ss)
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To: Red Badger

Please put me on your ping list. My mother has had tinnitus for years. Now she has Alzheimer’s or some kind of dementia. I wonder if there could be any relation?


35 posted on 05/04/2011 9:32:43 AM PDT by TigersEye (Who crashed the markets on 9/15/08 and why?)
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To: AaronInCarolina
...How does one take Chromium? As a pill form, or dietary supplement?...

You can get Chromium (and B-12 which supposedly helps tinnitus per Bulwinkle's link) in a multivitamin.

36 posted on 05/04/2011 9:37:42 AM PDT by FReepaholic (Land of the free my @ss)
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To: Bulwinkle

“I have the ‘crickets’ type...”

I do too! Only have it in my right ear, it comes and goes, and sometimes makes me dizzy. It occurs at night a lot, when I’m lying in bed. I’ve had it for about 6 years; started off as an inner ear infection. I ignore it as much as possible.


37 posted on 05/04/2011 9:39:26 AM PDT by Old Grumpy
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To: far sider

me too. I’m pretty sure mine’s from a gun going off without ear protection AND a very loud horn but I’d sure love to find something to give me relief.


38 posted on 05/04/2011 9:46:39 AM PDT by spacejunkie2001
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To: Red Badger
I'm ringing you up!

Thanks.

39 posted on 05/04/2011 10:06:17 AM PDT by Doomonyou (Let them eat Lead.)
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To: I still care

Interesting!
But isn’t chromium toxic?


40 posted on 05/04/2011 10:07:59 AM PDT by dusttoyou ("Progressives" are wee-weeing all over themselves, Foc nobama)
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To: PetroniusMaximus
re: high pitched sound given off by the old TV sets

Interesting you should say that. I can remember as a youngster walking down the sidewalk and hearing that sound coming from houses where they were watching TV. Usually those with me did not hear it, or didn't hear it until I called their attention to it. I always thought it strange that I would hear and others wouldn't. I decided it was because I was more sensitive to high pitch sounds than some others.

I am 70-years-old now and have a real problem with tinnitus. It seems to be a familial thing, my dad had it. We always thought he developed it because as a young man he had worked in the shipyard as a riveter. Talk about a loud noise! But now I have it too and I never was exposed as he was.

I have to wonder if maybe those who are particularly sensitive to high pitched sounds as I was are more prone to developing it later in life.

I had not thought about that sound from TV’s in years! Thanks for the memory jog.

41 posted on 05/04/2011 10:34:23 AM PDT by jwparkerjr (I would rather lose with Sarah than win with a RINO!)
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To: Red Badger

Please add me. I would love to one day know what silence sounds like.


42 posted on 05/04/2011 10:37:48 AM PDT by Zionist Conspirator (Ki-hagoy vehamamlakhah 'asher lo'-ya`avdukh yove'du; vehagoyim charov yecheravu.)
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To: I still care; HereInTheHeartland
I had to place the palms of my hands flat on the mattress to stop the “spins” at night when I slept.

Sounds more like Meniere's disease

43 posted on 05/04/2011 10:37:48 AM PDT by Sarajevo (Avoid arguments with your wife about lifting the toilet seat by simply using the sink.)
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To: Bulwinkle
I have the ‘crickets’ type

Me too. Though sometimes it sounds like grasshoppers, sometime like dry flies (cicadas), and sometimes like frogs singing.

44 posted on 05/04/2011 10:40:56 AM PDT by Zionist Conspirator (Ki-hagoy vehamamlakhah 'asher lo'-ya`avdukh yove'du; vehagoyim charov yecheravu.)
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To: Zionist Conspirator
I would love to one day know what silence sounds like.

Me too.

Here's a clue: Forget to buy your wife a Mother's Day card or gift. You will find out.............

45 posted on 05/04/2011 10:53:52 AM PDT by Red Badger (Mitt Romney: The Harold Stassen of the 21st century........)
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To: dusttoyou
But isn’t chromium toxic?

Only if it's on the bumper of a 64 Chevy coming at you at 60 mph..........

46 posted on 05/04/2011 10:55:28 AM PDT by Red Badger (Mitt Romney: The Harold Stassen of the 21st century........)
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To: jwparkerjr; reed13; Vermont Lt; HereInTheHeartland; FourPeas

“re: high pitched sound given off by the old TV sets... I have to wonder if maybe those who are particularly sensitive to high pitched sounds as I was are more prone to developing it later in life.”

I think you might be on to something.

I could also hear that sound when I was a child (and others I knew couldn’t). Several on this thread indicate similar experiences.


47 posted on 05/04/2011 11:02:03 AM PDT by PetroniusMaximus
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To: Red Badger

Please add me to your ping list! Thanks.


48 posted on 05/04/2011 11:09:57 AM PDT by TruthConquers (.Delendae sunt publicae scholae)
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To: TruthConquers

Done!...........


49 posted on 05/04/2011 11:15:48 AM PDT by Red Badger (Mitt Romney: The Harold Stassen of the 21st century........)
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To: Red Badger

Please sign me up to your ping list! Thanks, Vor Lady


50 posted on 05/04/2011 12:03:06 PM PDT by Vor Lady (Happy bin Laden is Dead Day!)
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