Skip to comments.S.A.N.E Vax, INC Supports Bachmann Gardasil/Mental Retardation Charge
Posted on 09/19/2011 11:58:20 AM PDT by To-Whose-Benefit?
click here to read article
So why did Perry apologize?
(And I give him credit for that.)
Youve disposed of my percentages of young girls seriously harmed by HPV vaccines based on an error in my methodology.
AERs are reported to Government Regulators on a voluntary basis, and very few of them are actually reported.
Drug Saf. 2006;29(5):385-96.
Under-reporting of adverse drug reactions : a systematic review.
Hazell L, Shakir SA.
Drug Safety Research Unit, Southampton, UK.
The purpose of this review was to estimate the extent of under-reporting of adverse drug reactions (ADRs) to spontaneous reporting systems and to investigate whether there are differences between different types of ADRs. A systematic literature search was carried out to identify studies providing a numerical estimate of under-reporting. Studies were included regardless of the methodology used or the setting, e.g. hospital versus general practice. Estimates of under-reporting were either extracted directly from the published study or calculated from the study data. These were expressed as the percentage of ADRs detected from intensive data collection that were not reported to the relevant local, regional or national spontaneous reporting systems. The median under-reporting rate was calculated across all studies and within subcategories of studies using different methods or settings. In total, 37 studies using a wide variety of surveillance methods were identified from 12 countries. These generated 43 numerical estimates of under-reporting. The median under-reporting rate across the 37 studies was 94% (interquartile range 82-98%). There was no significant difference in the median under-reporting rates calculated for general practice and hospital-based studies. Five of the ten general practice studies provided evidence of a higher median under-reporting rate for all ADRs compared with more serious or severe ADRs (95% and 80%, respectively). In comparison, for five of the eight hospital-based studies the median under-reporting rate for more serious or severe ADRs remained high (95%). The median under-reporting rate was lower for 19 studies investigating specific serious/severe ADR-drug combinations but was still high at 85%. This systematic review provides evidence of significant and widespread under-reporting of ADRs to spontaneous reporting systems including serious or severe ADRs. Further work is required to assess the impact of under-reporting on public health decisions and the effects of initiatives to improve reporting such as internet reporting, pharmacist/nurse reporting and direct patient reporting as well as improved education and training of healthcare professionals.
PMID: 16689555 [PubMed - indexed for MEDLINE]
And based upon that, Ill stick with my 6 out of every 100 number. Thank you for helping me refine this issue into better documented and clearer focus.