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Brown Fat, Triggered by Cold or Exercise, May Yield a Key to Weight Control
NY Times ^ | January 24, 2012 | GINA KOLATA

Posted on 01/25/2012 1:38:32 PM PST by neverdem

Fat people have less than thin people. Older people have less than younger people. Men have less than younger women.

It is brown fat, actually brown in color, and its great appeal is that it burns calories like a furnace...

--snip--

The brown fat also kept its subjects warm. The more brown fat a man had, the colder he could get before he started to shiver.

Brown fat, Dr. Carpentier and Jan Nedergaard, Dr. Cannon’s husband, wrote in an accompanying editorial, “is on fire.”

On average, Dr. Carpentier said, the brown fat burned about 250 calories over three hours.

But there is another type of brown fat. It has been harder to study because it often is interspersed in the white fat and does not occur in large masses. Investigators discovered it in mice years ago. Now, in a recent article, Bruce Spiegelman, professor of cell biology and medicine at the Dana-Farber Cancer Institute, and his colleagues report that, in mice at least, exercise can make it appear, by turning ordinary white fat brown.

When mice exercise, their muscle cells release a newly discovered hormone that the researchers named irisin. Irisin, in turn, converts white fat cells into brown ones. Those brown fat cells burn extra calories.

Dr. Spiegelman said the brown fat he studies is different from the type that appears in large, distinct masses in rodents, the type Dr. Carpentier was examining in his subjects. That brown fat is derived from musclelike cells and not from white fat.

Dr. Spiegelman suspects that humans, like mice, make brown fat from white fat when they exercise, because humans also have irisin in their blood. And human irisin is identical to mouse irisin...

(Excerpt) Read more at nytimes.com ...


TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: brownfat; irisin; obesity; type2diabetes; weightcontrol; weightloss
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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
1 posted on 01/25/2012 1:38:39 PM PST by neverdem
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To: neverdem

dammit...

when are they going to discover something that makes me thin without having to exercise


2 posted on 01/25/2012 1:41:11 PM PST by Mr. K (Physically unable to profreed <--- oops, see?)
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To: neverdem

I’ll take a gallon of brown fat please...some of that there beef jerky.


3 posted on 01/25/2012 1:41:35 PM PST by RoosterRedux (Newt: "Why vote for the guy who lost to the guy who lost to Obama?")
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To: neverdem

“Brown Fat, Triggered by Cold or Exercise, May Yield a Key to Weight Control”

Not another Moo-chelle thread!


4 posted on 01/25/2012 1:47:02 PM PST by Batman11 (Obama's poll numbers are so low the Kenyans are claiming he was born in the USA!)
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To: call meVeronica

Bump


5 posted on 01/25/2012 1:49:53 PM PST by call meVeronica
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To: call meVeronica

Bump


6 posted on 01/25/2012 1:50:35 PM PST by call meVeronica
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To: call meVeronica

Grrrraaaaavvvvyyyyyyyy


7 posted on 01/25/2012 1:55:34 PM PST by jacksonstate
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To: neverdem

So as I see it, if I stay with Chocolate ice-cream (brown fat), I’ll win at this. ;>)


8 posted on 01/25/2012 1:58:21 PM PST by Gator113 (~Just livin' life, my way~..... GO NEWT GO.....!)
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To: Mr. K
...when are they going to discover something that makes me thin without having to exercise?

I think they just did.

Irisin injections.

9 posted on 01/25/2012 2:14:41 PM PST by Bloody Sam Roberts ("The price of freedom is willingness to do sudden battle anywhere, anytime..." - Robert A. Heinlein)
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To: Mr. K

Turn down the thermostat


10 posted on 01/25/2012 2:18:06 PM PST by School of Rational Thought
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To: neverdem
"May Yield a Key to Weight Control"

Errrr... don't eat more calories than you burn. That's pretty simple, don't-cha thunk!


11 posted on 01/25/2012 2:18:06 PM PST by avacado
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To: Mr. K

Turn down the thermostat


12 posted on 01/25/2012 2:18:20 PM PST by School of Rational Thought
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To: Mr. K

Turn down the thermostat


13 posted on 01/25/2012 2:18:26 PM PST by School of Rational Thought
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To: neverdem

Brown fat? Where’s the little kid that says, “That’s racist!!!”


14 posted on 01/25/2012 2:20:06 PM PST by Veggie Todd (I don't mind you hitting me, Frank, but take it easy on the Bacardi.)
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To: All


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15 posted on 01/25/2012 2:32:36 PM PST by musicman (Until I see the REAL Long Form Vault BC, he's just "PRES__ENT" Obama = Without "ID")
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To: neverdem
Brown Fat, Triggered by Cold or Exercise, May Yield a Key to Weight Control

He may be useful after all.

16 posted on 01/25/2012 2:33:00 PM PST by martin_fierro (< |:)~)
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To: neverdem

bttt


17 posted on 01/25/2012 2:45:33 PM PST by netmilsmom (Happiness is a choice)
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To: Mr. K

...And all the discoveries will lead to something miraculous for weight loss down the road and it never happens.


18 posted on 01/25/2012 2:56:17 PM PST by Anti-Bubba182
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To: Mr. K

Stomach flu or the concentration camp diet both do that well. Of course you’ll quickly find exercise not so bad after those.


19 posted on 01/25/2012 2:59:06 PM PST by discostu (How Will I Laugh Tomorrow When I Can't Even Smile Today)
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To: neverdem

I knew all of this 20 years ago.


20 posted on 01/25/2012 3:00:01 PM PST by JustaDumbBlonde (Don't wish doom on your enemies ... plan it.)
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