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Vaccine trial reveals chinks in HIV's armour
NATURE NEWS ^ | 10 September 2012 | Ewen Callaway

Posted on 09/11/2012 12:24:41 AM PDT by neverdem

Analysis identifies target for immune response that could improve AIDS vaccines.

HIV is finally revealing its weak spots to researchers, bringing an effective vaccine against AIDS closer to reality.

A paper published in Nature today1 sheds light on how a vaccine can turn the immune system against the invading virus and so offer protection from infection. The results are also being presented at the AIDS Vaccine 2012 conference in Boston, Massachusetts, this week.

The findings help to explain the results from a clinical trial of an AIDS vaccine that have puzzled researchers since they were published three years ago2. The trial, called RV144, was the first to score a success and see a reduction in HIV infections. But the vaccine’s relatively low response rate of 31% left researchers scratching their heads.

A clue emerged last year with the revelation that those who responded to the vaccine and fended off HIV tended to produce antibodies against a specific part of the virus's protein shell called the V1/V2 loop3. The study published today goes a stage further, showing that the people who were vaccinated yet still contracted HIV had been infected by viruses that had mutations in the the V2 portion.

“This is a really good paper,” says Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, Maryland. “It adds to the growing body of information indicating that an immune response against components of the V1/V2 loop is important in vaccine-induced protection against infection.”...

(Excerpt) Read more at ...

TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: hiv; hivvaccine; immunology; microbiology; rv144

1 posted on 09/11/2012 12:24:54 AM PDT by neverdem
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To: neverdem

There is NO AIDs vaccine. AIDs is a ‘Syndrome’ of over 30 separate diseases which have been tied to the HIV retrovirus. The writer of this drivel is so stupid that she doesn’t even understand the difference. By the way: HIV is a harmless, ubiquitous 9 kilo base retrovirus and it does NOT cause AIDs. Homo fraud since the ‘Lancet’ article. What an incredible con and waste of money. Pathetic!

2 posted on 09/11/2012 7:11:04 AM PDT by Doc Savage ("I've shot people I like a lot more,...for a lot less!" Raylan Givins)
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