Meant to add — Although I’ve only experienced one full-blown panic attack (one’s quite enough, thank you), a relative had ongoing problems. About as bad as anything you can think of during that sheer terror phase. I remember the impending sense of doom also. Much worse (100x) than the usual worrying about Obamacare or something like that. I use Kava for anxiety control when necessary — have on and off for 15 years — and it is effective.
I don’t know your views on God but prayer turned out to be the biggest help of all. The peace of God was the answer for me. I still take dietary supplements but haven’t needed anything for depression or anxiety since 2008. Didn’t need any before that year either but I was laboring under the illusion that I could do it all myself up to that point.
SAM-e does have health benefits above and beyond mood stabilization though, as I mentioned. I had a positive experience with the use of it, enteric coated caplets from GNC. Should I experience joint pain from inflammation I wouldn’t hesitate to use it again.