Skip to comments.Tylenol maker tries new warning cap to curb overdoses
Posted on 08/30/2013 8:59:41 AM PDT by NautiNurse
click here to read article
Years ago, I heard one of the leading pharmacologists in the world go after acetaminophen and the salt substitutes for being bs that was foisted on Americans and Euros.
Acetaminophen as you noted later in this thread does not work for aches and pains and only works to reduce fever.
Acetaminophen has a low LD50 by itself in normal people and is more dangerous in people with bad livers, like people who have more than 2 drinks a day.
Acetaminophen drug levels can be increased by many common drugs and foods.
Acetaminophen is combined with what seems to be an endless group of other otc drugs, so unintentional ODs can happen when Acetaminophen is added to these otc drugs.
A very few people should not take aspirin, so Acetaminophen may be needed if they have high fevers.
I don’t take acetaminophen because for me, it’s not that effective a painkiller. Now, ibuprofen, on the other hand....
I take stuff with Chlorpheniramine Maleate and Phenylephrine HCl in it, but it also has acetaminophen. This article has convinced me to find (and I did, in Walgreens, online) the same two ingredients in something WITHOUT acetaminophen. Thanks guys!
I take aspirin. I might as well drink a glass of water as take two Tylenol.
I tend to read labels so I am not in any danger from acetaminophen. I trust that most FReepers do likewise. The ignorant and the foolish have the trial lawyers to take care of them.
This could have happened to my Son last week. He woke up with a 101 fever and severe sinus congestion. I said “wait, don’t take anything, I’m going to the store to get Mucinex and a new thermometer”. I can never get those ear thermometers to work, and wanted one of those forehead swipe ones. By the time I got back 20 minutes later my soon to be ex-wife had given him TWO extra strength tylenol without telling me. This is double his dose by body weight. Thank God he asked if there was Acetaminophen in the Mucinex, or I would given him 600 mg more. Fun times.
Just saying what the doctor said to me.
Of course, I doubt if you will wake up every three hours in the night to take them.
I began taking magnesium after someone posted an article on FR a month ago and haven’t had but one headache since. I had frequent headaches before. I have been sleeping through the night and getting 7-8 hrs. every night. I built up to 800 mg/day of magnesium glycinate. I haven’t had Tylenol or aspirin since.
Recommended dose was dropped to below 3.5 grams per day (extra strength tabs are 500 mg each so 7 tabs per day is maximum). If you take the time to read the literature, you can diminish the hepatotoxic effects by taking 600 mg of N-acetyl-cysteine as well as vitamin C. NAC is what is used in emergency rooms for an overdose. The problem is that as has been said, acetaminophen is used in so many other products that the dose becomes cumulative; pharmacists are concerned that a lot of the “high dose” pain killers contain acetaminophen as well. That is why the recommended dose was dropped.
As for ibuprofen, that also causes problems with the kidneys when used to excess. I’ve sworn off the stuff completely.
“Tylenol... is not an anti-inflammatory”
That’s incorrect. Tylenol is also a potent anti-inflammatory.
I think the idea of alternating acetaminophen and aspirin is a great idea. I’ve often thought about doing that myself when necessary.
Aspirin aside, acetaminophen is actually by far the safest of the other NSAIDs if one has heart disease, as ALL NSAIDs except aspirin increase the chance of heart attack, substantially in some cases. Acetaminophen has the smallest increase of heart attacks of the non-aspirin NSAIDs.
That being said, one has to be VERY careful to not OD on acetaminophen or it will destroy your liver and kill you. The biggest difficulty is that acetaminophen is an ingredient in so many different combination remedies, it can be difficult to know if you’re taking too much.
I once worked with a woman who took enormous amounts of acetaminophen for her headaches; she also drank heavily (not in the office, though). I warned her repeatedly of the dangers of doing that, but to no avail. One day she died of acute liver failure.
The irony of this is that acetaminophen is a poison to most mammals, reptiles, birds and fish. Humans are unusual in that they can take some of it for therapeutic reasons.
In Guam, there are invasive snakes that the government wants to eradicate. To do this, dead mice have an acetaminophen pills inserted into them, a small parachute tied to them, and they are dropped by aircraft into the jungle.
"I smell a rat," said the snake. No self-respecting snake would eat a dead mouse, much less one that parachuted into the jungle.
Cite your source, Bucky. The Tylenol company does not claim acetaminophen to be an anti-inflammatory. Other than that, you don't know what you are talking about.
Ibuprofen (Advil, etc.) is a powerful anti-inflammatory and fever reducer. Never exceed the daily recommended dose, and drink plenty of fluids (ahem..water) when taking ibuprofen or other NSAIDS. They can be toxic to the kidneys.
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