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News In Brief: Fructose may be key to weight gain
www.sciencenews.org ^ | September 9, 2013 | By Nathan Seppa

Posted on 09/10/2013 12:44:32 PM PDT by Red Badger

Mice that could not make or metabolize the sugar gained less than normal mice.

Mice lacking the ability to metabolize fructose don’t gain nearly as much weight as normal mice do, researchers report September 10 in Nature Communications.

Fructose, which some people blame for the obesity epidemic and its related health crises (SN: 6/1/13, p. 22), shows up in high-fructose corn syrup and in table sugar, or sucrose. The body also makes home-grown fructose by modifying glucose in a process involving an enzyme called aldose reductase.

(Excerpt) Read more at sciencenews.org ...


TOPICS: Business/Economy; Culture/Society
KEYWORDS: cornsyrup; fructose; hfcs; nutrition; obesity; sugar; type2diabetes
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1 posted on 09/10/2013 12:44:32 PM PDT by Red Badger
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To: Red Badger

my vote is that the fork is the main contributor to weight gain


2 posted on 09/10/2013 12:47:19 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
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To: NativeSon

So we should blame Big Silverware?.............


3 posted on 09/10/2013 12:48:10 PM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: Red Badger

The evil flatware company, Oneida!


4 posted on 09/10/2013 12:49:32 PM PDT by Marie Antoinette (:)
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To: Red Badger

I thought the DemocRATS were blaming obesity on “climate change”. Like chipmunks, people were storing fat for the upcoming, severe global warming winter and ice age.


5 posted on 09/10/2013 12:50:03 PM PDT by FlingWingFlyer (The time for impeachment has come.)
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To: Marie Antoinette

And Paul Revere..........


6 posted on 09/10/2013 12:51:42 PM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: Red Badger

Google “Robert Lustig” on the subject of fructose, along with his YouTube speeches.


7 posted on 09/10/2013 12:53:52 PM PDT by Kennard
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To: Kennard

http://www.freerepublic.com/focus/f-news/3065106/posts


8 posted on 09/10/2013 12:56:10 PM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: Red Badger
Fructose, which some people blame for the obesity epidemic and its related health crises (SN: 6/1/13, p. 22), shows up in high-fructose corn syrup and in table sugar, or sucrose.

He really wrote this? Fructose shows up in Sucrose?

And this guy is a science writer?

9 posted on 09/10/2013 12:59:25 PM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120) Cure Alzheimer's!)
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To: Red Badger

This is news?

How about ‘fat people tend to weigh more than thin people do on average’ ?


10 posted on 09/10/2013 1:01:29 PM PDT by sickoflibs (To GOP : Any path to US Citizenship IS putting them ahead in line. Stop lying about your position.)
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To: texas booster

Doesn’t it?


11 posted on 09/10/2013 1:03:36 PM PDT by 9YearLurker
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To: texas booster

“(Sucros)is a disaccharide composed of the monosaccharides glucose and fructose.... “


12 posted on 09/10/2013 1:12:27 PM PDT by Paradox (Unexpected things coming for the next few years.)
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To: 9YearLurker
no, it's not “found in” sucrose. the monomer is in the molecule but that like saying that “man” is found in a female be she is a “woman” .. ok, not the best analogy
13 posted on 09/10/2013 1:12:43 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
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To: Paradox
sucrose is a molecule must be chemically acted upon to break into the constituents
14 posted on 09/10/2013 1:14:19 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
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To: Red Badger

He was hungry for those good things


15 posted on 09/10/2013 1:15:46 PM PDT by Freestate316 (Know what you believe and why you believe it.)
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To: NativeSon

Indeed, which occurs readily in the mammalian gut.


16 posted on 09/10/2013 1:17:05 PM PDT by Paradox (Unexpected things coming for the next few years.)
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To: Red Badger

We must ban high capacity utensils!


17 posted on 09/10/2013 1:17:07 PM PDT by Freestate316 (Know what you believe and why you believe it.)
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To: NativeSon

You completely lost me in the man-woman analogy.

As far as I understand it, fructose is a component of sucrose, which is all he’s getting at.


18 posted on 09/10/2013 1:26:35 PM PDT by 9YearLurker
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To: NativeSon

But doesn’t that breakdown occur in digestion?


19 posted on 09/10/2013 1:27:21 PM PDT by 9YearLurker
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To: Freestate316

20 posted on 09/10/2013 1:28:03 PM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: NativeSon; Paradox
Although glucose can be metabolized by every cell in the body, fructose is metabolized almost entirely by the liver. There it can result in the generation of free radicals (damaged cells that can damage other cells) and uric acid (which can lead to kidney disease or gout), and it can kick off a process called de novo lipogenesis, which generates fats that can find their way into the bloodstream or be deposited on the liver itself. These byproducts are linked to obesity, insulin resistance and the group of risk factors linked to diabetes, heart disease and stroke. (Lustig gives a detailed explanation of fructose metabolism in a well-viewed YouTube video called "Sugar: The Bitter Truth.")

http://www.freerepublic.com/focus/f-chat/3065106/posts

21 posted on 09/10/2013 1:30:07 PM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: Red Badger

Another one of those useless ‘studies’.


22 posted on 09/10/2013 1:33:13 PM PDT by I want the USA back
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To: 9YearLurker

breakdown - destruction of the monomer or clip the linkages?


23 posted on 09/10/2013 1:33:35 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
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To: I want the USA back

Stay healthy, eat your honey...


24 posted on 09/10/2013 1:41:01 PM PDT by refermech
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To: Red Badger
These byproducts are linked to obesity, insulin resistance and the group of risk factors linked to diabetes, heart disease and stroke

Regardless of the biochemical pathways, Fructose is found in plants, as with many other compounds found in nature, we are "designed" to process it...

The end of those reactions produce molecules critical to our function. Like cholesterol, cholesterol is fantastic, without it, well, say good by to bi-lipid membranes for starters...

The issue here is dosage- stop stuffing your gob with anything that resembles an edible and most of the "modern problems" will clear up.

25 posted on 09/10/2013 1:44:14 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
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To: 9YearLurker
man/woman analogy. I use it to cover chemisty topics with non chemists. See, fructose is not a component of sucrose, you will never boil/steam/filter/sift it out. Just like the word "man" is in "woman" does mean that you can extract the man...

um, unless in San Fran or Thailand... but I digress.

26 posted on 09/10/2013 1:48:39 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
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To: NativeSon

Still a wacky analogy.

But lots of components can’t be boil/steam/filter/sifted out of things.


27 posted on 09/10/2013 2:14:35 PM PDT by 9YearLurker
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To: NativeSon

Here ya go:

“When fructose is consumed in the form of sucrose, it is digested (broken down) and then absorbed as free fructose. As sucrose comes into contact with the membrane of the small intestine, the enzyme sucrase catalyzes the cleavage of sucrose to yield one glucose unit and one fructose unit, which are then each absorbed.”

http://en.wikipedia.org/wiki/Fructose


28 posted on 09/10/2013 2:18:28 PM PDT by 9YearLurker
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To: NativeSon

29 posted on 09/10/2013 3:04:53 PM PDT by MCH
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To: Red Badger

People drank soda since it was invented but after the switch from real sugar to corn syrup, bad things seemed to happen.

Sugar tasted better too.


30 posted on 09/10/2013 3:06:24 PM PDT by GeronL
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To: Red Badger

Having been into amateur body building a long time ago, I have known about the problems with fructose long before its recent infamy. Sucrose include fructose, so too much of that is a bad thing too.


31 posted on 09/10/2013 4:25:35 PM PDT by Paradox (Unexpected things coming for the next few years.)
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To: texas booster
He really wrote this? Fructose shows up in Sucrose?

And this guy is a science writer?

One who knows better than to piss off Big Corn - thus softening the blow with, "Sugar causes it, too." :)

32 posted on 09/10/2013 4:29:30 PM PDT by Mr. Jeeves (CTRL-GALT-DELETE)
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To: GeronL
People drank soda since it was invented but after the switch from real sugar to corn syrup, bad things seemed to happen.

Funny, I prefer the taste of corn syrup (100% glucose) to sugar (sucrose which is metabolized to 50% glucose and 50% fructose). You might be confused and instead mean "high-fructose corn syrup" which is normal corn syrup catalyzed to about 55% fructose and 42% glucose. This ratio, incidentally, is the same as natural honey. The only real difference between natural honey and synthetic high fructose corn syrup is the traces of pollen in the honey.

33 posted on 09/10/2013 4:39:27 PM PDT by Ronaldus Magnus
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To: 9YearLurker
Now that - enzymatic cleavage- is what happens. Still doesn't mean that it is bad for you but you do get "2 for price of one" out of it.

if you have any interest, pick up a biochemistry text, truly amazing to understand some of the chemistry of our bodies.

here's an interesting biochem tip- if you happen to drink a wee bit much, drink something with a lot of glucose (or sucrose) before going to bed. For the extra credit, why?

34 posted on 09/10/2013 8:03:35 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
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To: 9YearLurker
But lots of components can’t be boil/steam/filter/sifted out of things.

a mixture can be separated by mechanical/physical means. So the sugar in 'grape drank' can separated by boiling off the aqueous portion and crystalizing the sugar. The sugar molecule however will remain unchanged.

or in biology, I can spin your blood down and separate the solids and the bits but the oxygen bonded to your prosthetic group of the porphyrin rings will remain chemically bonded.

35 posted on 09/10/2013 8:13:12 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
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To: NativeSon

You’re giving me the tutorial now?


36 posted on 09/10/2013 11:32:42 PM PDT by 9YearLurker
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To: 9YearLurker

Just sharing my enjoyment of chemistry ...


37 posted on 09/11/2013 3:17:23 AM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
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To: GeronL

Oddly, Mexico does not allow HFCS to be used in soft drinks, raw sugar only. Big Lots sells some Mexican soft drinks, including imported Coca-Cola! You can get that old-fashioned taste for about a dollar a bottle (yes they are still in the old green glass Coke bottles!)...............


38 posted on 09/11/2013 6:28:55 AM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: Paradox

Too much of anything can be bad for you, health-wise, but HFCS should be very limited intake........


39 posted on 09/11/2013 6:30:39 AM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: Red Badger

They keep reusing those bottles.


40 posted on 09/11/2013 6:30:49 AM PDT by GeronL
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To: GeronL

So did all the soft drink companies up until the 70’s or so. When I was a kid, finding discarded coke bottles was my main source of ‘income’ . Every Saturday I would ride around town and pick up all the coke bottles from ditches and sides of the road to turn in for deposit. At 2 cents apiece I could make a dollar just about every weekend, usually more. That would support my comic book habit, and later my tab at the pool hall................Yes, I had a tab at the local pool hall at 13!...............


41 posted on 09/11/2013 6:36:27 AM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: Red Badger

I played pool occasionally at the roller skating rink but I was never really into it.


42 posted on 09/11/2013 6:44:46 AM PDT by GeronL
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To: Red Badger

Well, Jane, it just goes to show you, it's always something! If it's not one thing, it's another! - Roseanne Roseannadanna

43 posted on 09/11/2013 6:45:26 AM PDT by McGruff (No wars for Arab pipelines!)
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To: GeronL

The local pool hall in my town charged 5 cents for a regular pool game (billiards, 8 ball, 9 ball, Cut Throat) and 10 cents for Snooker. I kept my tab to a dollar a week, and mostly played regular pool games. Snooker was more fun, but the cost limited my playing time..................


44 posted on 09/11/2013 6:49:23 AM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: Red Badger
Too much of anything can be bad for you, health-wise, but HFCS should be very limited intake........

Yes, but the fact is, Sucrose is not a whole lot better.

45 posted on 09/11/2013 10:22:40 AM PDT by Paradox (Unexpected things coming for the next few years.)
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To: Paradox

From following Link:

Although glucose can be metabolized by every cell in the body, fructose is metabolized almost entirely by the liver. There it can result in the generation of free radicals (damaged cells that can damage other cells) and uric acid (which can lead to kidney disease or gout), and it can kick off a process called de novo lipogenesis, which generates fats that can find their way into the bloodstream or be deposited on the liver itself. These byproducts are linked to obesity, insulin resistance and the group of risk factors linked to diabetes, heart disease and stroke. (Lustig gives a detailed explanation of fructose metabolism in a well-viewed YouTube video called “Sugar: The Bitter Truth.”)

http://www.freerepublic.com/focus/f-chat/3065106/posts


46 posted on 09/11/2013 10:32:35 AM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: Red Badger

Sucrose is not glucose. It is glucose-fructose.


47 posted on 09/11/2013 10:34:49 AM PDT by Paradox (Unexpected things coming for the next few years.)
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To: Paradox

This is true. But it ain’t fructose-fructose............


48 posted on 09/11/2013 10:36:09 AM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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To: Red Badger

Neither is HFCS.


49 posted on 09/11/2013 10:41:07 AM PDT by Paradox (Unexpected things coming for the next few years.)
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To: Paradox

But it is High Fructose as compared to sucrose..........


50 posted on 09/11/2013 11:32:05 AM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
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