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Making Babies with 3 Genetic Parents Gets FDA Hearing (Opening Frankenstein-ian Floodgates)
Scientific American ^ | February 25, 2014 | Dina Fine Maron

Posted on 03/04/2014 11:56:48 AM PST by lbryce

Making Babies with 3 Genetic Parents Gets FDA Hearing A reproductive technology that taps three parents’ DNA as a way to eliminate hereditary diseases could reach clinical trials if the Food and Drug Administration gives the go-ahead.

Reproductive technologies that marry DNA from three individuals will receive a trial in the court of public opinion this week. Such technologies may hold promise for averting certain genetically inherited diseases passed down via mutations to mitochondria, the cell’s battery pack.

Scientists have already had successes with this type of reproductive approach in monkeys and in human embryos, and are now eager to launch human clinical trials. First, however, they must get the green light from the U.S. Food and Drug Administration, which will convene a public hearing before an advisory committee on February 25.

The technology, called oocyte modification (but sometimes nicknamed “three-parent IVF”), involves scooping out potentially mutated mitochondrial DNA (mtDNA) from a woman’s egg and replacing it with the mtDNA of an unaffected donor woman. The process is designed to prevent the transmission of some debilitating inherited mitochondrial diseases, which can result in vision loss, seizures and other maladies. Such inherited diseases, often unfortunately known by acronyms for complex medical names that include LHON, for Leber's Hereditary Optic Neuropathy, along with MELAS, MERRF and NARP, occur in about one in every 5,000 live births and are incurable.

(Excerpt) Read more at scientificamerican.com ...


TOPICS: Culture/Society; Extended News; Government
KEYWORDS: bho44; bhofda; bioethics; frakenstein; playinggod
Science, scientists have a nefarious proclivity to delve into forbidden realms of the natural world of which they have absolutely no moral, ethical, practical right to tread, infiltrate. In particular, the science of human reproduction is fraught with infinite issues, conundrums, that reaches out all across the scientific, ethical, moral, religious spectrum. They have the egregious audacity, hubris to pretend they have the answers we seek, to speak of in the name of of matters regarding which they are woefully incapable, inept in, making claims, setting boundaries, defining realities infinitely beyond which they have the slightest authority, wherewithal to do so.

And yet, science will forge ahead confronting the exceedingly complex dynamics of which becomes exponentially herculean in its effort to unravel the secrets to its very own seeming omnipotence, based on what it has up until now accomplished for humanity to overwhelmingly ambition and success.

The law of diminishing returns may yet bring science to its knees but it is the very ideology of science of what man can conceive he will achieve that provides the impetus for the belief that there are no limits, science can, will conquer all but one in which may very well be its very undoing.

In a Cosmos of that which was brought forth by a Supreme Being,it is inevitable that science in practical terms will eventually catch up with its very own self-deluding ambitions in reaching the point in which it can go no further as demonstrated by the proverbial irresistible force paradox, in which it will get to validate its very own ideology of no limitations as fallacy.

1 posted on 03/04/2014 11:56:48 AM PST by lbryce
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To: lbryce

I wonder, we already have male and female. will these babies be the new middle sex? Will they have extra ears or eyes?


2 posted on 03/04/2014 11:58:39 AM PST by buffyt (The only person who is safe in a gun free area is THE MANIAC WITH A GUN!)
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To: buffyt

No.


3 posted on 03/04/2014 12:07:11 PM PST by TexasGator
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To: lbryce

Serious question:

Setting aside for a moment the moral and ethical and religious issues of in-vitro fertilization from 3rd-party parents, how is this different, morally, than giving a person an aspirin to modify a headache?


4 posted on 03/04/2014 12:12:32 PM PST by mbarker12474
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To: lbryce

Eugenics on the way to a clinic near you. Designer babies for the ultra rich.


5 posted on 03/04/2014 12:21:07 PM PST by 12th_Monkey (One man one vote is a big fail, when the "one" man is an idiot.)
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To: mbarker12474

This is not a serious question.

First you say to set aside the moral and then you say how is this different morally?

I didn’t realize that taking an aspirin modified your DNA and created new life.

Think you need to come up with a better argument than this.


6 posted on 03/04/2014 12:23:24 PM PST by Guardian Sebastian (Mother of God, pray for us and our country.)
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To: Guardian Sebastian

How is the genetic aspect in and of itself different?

I see moral, ethical, and religious issues with in-vitro fertilization from 3rd parties, in and of itself.

I’m looking for additional issues having to do with the DNA aspect in and of itself. Setting aside, for the sake of analysis, the 3rd party conception issues.


7 posted on 03/04/2014 12:27:28 PM PST by mbarker12474
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To: lbryce

And failures will be thrown in the trash. Thousands of failures. Until one day, they declare “success!” and get on the front page of every paper in the country.

Of course they will feel nothing is wrong with creating thousands of little humans, and destroying them.

Of course, feminazis and other mentally deficient individuals will applaud this.


8 posted on 03/04/2014 12:27:35 PM PST by I want the USA back (Media: completely irresponsible traitors. Complicit in the destruction of our country.)
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To: lbryce

Link to the full-text Free Republic thread.

9 posted on 03/04/2014 12:29:12 PM PST by Travis McGee (www.EnemiesForeignAndDomestic.com)
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To: buffyt

Why stop at three?

Why stop at humans? Why not combine people with humans with fish genetics so they can grow gills. or birds so they can grow wings??

HOW NUTTY CAN WE GET?????


10 posted on 03/04/2014 12:30:15 PM PST by ZULU (Magua is sitting in the Oval Office. Ted Cruz/Phil Robertson in 2016.)
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To: buffyt

I bet the real purpose is so two gay people can contribute to creation of a child.


11 posted on 03/04/2014 12:33:07 PM PST by MNDude
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To: buffyt
They will be a race of Al Franken-babies.
12 posted on 03/04/2014 12:33:32 PM PST by liberalh8ter (The only difference between flash mob 'urban yutes' and U.S. politicians is the hoodies.)
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To: mbarker12474
Serious question:

Setting aside for a moment the moral and ethical and religious issues of in-vitro fertilization from 3rd-party parents, how is this different, morally, than giving a person an aspirin to modify a headache?

This is more like a kidney or liver transplant, except it's at the cellular level.

And mitochondria are special as they appear to exist as a kind of separate organism living inside cells. They have their own DNA apart from the DNA inside the cell nucleus. Mitochondria could be endosymbionts living inside our cells. They might be related to the SAR11 clade of bacteria.

13 posted on 03/04/2014 12:35:29 PM PST by freerepublicchat
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To: I want the USA back

The scene in Alien Resurrection comes to mind when Ripley finds her predecessors.


14 posted on 03/04/2014 12:40:57 PM PST by Resolute Conservative
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To: lbryce

Lyrics from In The Year 2525 by Zager & Evans come to mind: “You’ll pick your son, pick your daughter, too, from the bottom of a long glass tube....”


15 posted on 03/04/2014 12:44:04 PM PST by NRA1995 (I'd rather be a living "gun culture" member than a dead anti-gun candy-ass.)
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To: lbryce

“As it was in the days of Noah...”


16 posted on 03/04/2014 12:48:51 PM PST by SouthernClaire
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To: I want the USA back

Oh My God! I wanted to delve into this subject, others on this issue but it was beginning to look like some thesis. Even as we speak there are innumerable chimerical human/animal fetuses created by science destroyed within days of “conception” in Japanese laboratories. They are destroyed because it is illegal to create human chimeras with animal DNA so they get destroyed to avoid violating the law.


17 posted on 03/04/2014 1:10:09 PM PST by lbryce (Obama:The Worst is Yet To Come)
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To: NRA1995

Rather prophetic except the date is about five centuries off.


18 posted on 03/04/2014 1:11:10 PM PST by lbryce (Obama:The Worst is Yet To Come)
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To: Resolute Conservative

The single one that was alive, conscious begging Ripley’s very far off genetic clone to “Please kill me”. (which she did by flame thrower.)


19 posted on 03/04/2014 1:13:17 PM PST by lbryce (Obama:The Worst is Yet To Come)
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To: liberalh8ter

Oh, please. Not.... as..... hideous... (as the Minnesota Monster.)


20 posted on 03/04/2014 1:14:47 PM PST by lbryce (Obama:The Worst is Yet To Come)
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To: mbarker12474

How is altering someone’s mitochondrial DNA and permanently altering humanity’s DNA germ line different from giving them an aspirin? Is that seriously a serious question?


21 posted on 03/04/2014 1:21:33 PM PST by Blackyce (French President Jacques Chirac: "As far as I'm concerned, war always means failure.")
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To: lbryce

I have my suspicions. I find no other plausible explanation for the mutation from Minnesota.


22 posted on 03/04/2014 1:24:00 PM PST by liberalh8ter (The only difference between flash mob 'urban yutes' and U.S. politicians is the hoodies.)
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To: lbryce

23 posted on 03/04/2014 3:18:44 PM PST by DannyTN
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