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A Fully Functional 3-D Printed Heart Sooner Than You Think
Qmed ^ | April 15, 2014 | Stephen Levy

Posted on 04/17/2014 8:15:44 AM PDT by null and void

Posted in Cardiovascular

The Cardiovascular Innovation Institute's executive and scientific director, Stuart K. Williams, PhD, has set his sights on a fully functional, implantable 3-D bioprinted human heart, which could provide a potential cure for heart disease.

“We think we can do it in 10 years — that we can build, from a patient’s own cells, a total ‘bioficial’ heart,” Williams, who is also a professor of surgery at the University of Louisville, told the Louisville Courier-Journal's Laura Ungar in an interview published on the Cardiovascular Innovation Institute (CII) website. The CII is a collaboration between the University of Louisville and the Jewish Heritage Fund for Excellence.

Williams explained that building a heart involves creating five interconnected systems — valves, coronary vessels, microcirculation, contractile cells and the organ’s electrical system. Six months ago, he said, they created and implanted a portion of a heart and blood vessels in mice.

Because bioprinted heart will be made from the patient's own fat cells, the problem of rejection will be eliminated. Williams said they are still working on whether the fat-derived cells will be coaxed into becoming cardiovascular cells in the lab or inside the body.

An internationally-known expert in biomedical engineering, Williams' research spans the fields of cardiovascular bioengineering, biomaterials and diabetes research. He holds a PhD in cell biology from the University of Delaware, and completed a postdoctoral fellowship in pathology at Yale University School of Medicine.

Before joining the faculty at the University of Louisville, Williams and his team at the University of Arizona received funds from the US Department of Defense to use 3-D printing to create lymph nodes, with the idea they could be implanted in the event of bioterrorism. To create the lymph nodes, accomplished in 2001, Williams and his Arizona team built a 3-D printer called the BioAssembly Tool (BAT) for about $400,000.

Williams brought the BAT to Louisville, to the CII, to concentrate on his main interest, the creation of blood vessels, cardiac structures and, eventually, a 3-D bioprinted heart to fight cardiovascular disease, which reportedly accounts for about three in 10 deaths in Kentucky.

“This was what killed my dad,” he told Ungar. “My dad was in congestive heart failure.”

“I think this will have an incredible effect on trauma patients … on the armed forces. You can imagine printing a jaw, printing muscle cells, printing the skin,” he said to Ungar. “Ultimately I see it being used to print replacement kidneys, to print livers, and to print hearts — and all from your own cells.”


TOPICS: Culture/Society
KEYWORDS: 3dprinter; 3dprinting; heart; organs
Adult stem cells.
1 posted on 04/17/2014 8:15:44 AM PDT by null and void
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To: AFPhys; AD from SpringBay; ADemocratNoMore; aimhigh; AnalogReigns; archy; ArrogantBustard; ...
3-D Printer Ping!

(My own 3-D printer is inches away from working)

2 posted on 04/17/2014 8:17:29 AM PDT by null and void (...if you are too sure of your place in heaven you might be too arrogant to actually get there.)
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To: null and void

“(My own 3-D printer is inches away from working) “

You got it. Congrats!


3 posted on 04/17/2014 8:21:35 AM PDT by Lurkina.n.Learnin
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To: null and void

Yay, nully!


4 posted on 04/17/2014 8:22:15 AM PDT by Silentgypsy (Make sure she doesnÂ’t get ahold of the gom jabbar.)
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To: null and void

Picard approves..

5 posted on 04/17/2014 8:28:40 AM PDT by GraceG
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To: null and void

Can they print the artificial muscles and whatever electronics are needed too?


6 posted on 04/17/2014 8:36:20 AM PDT by GeronL (Vote for Conservatives not for Republicans!)
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To: null and void
Another technology predicted by sci fi. Sci fi that PO'ed all true fans of Heinlein but thrilled fans of Denise Richard's rack, but there you have it.


7 posted on 04/17/2014 8:49:22 AM PDT by katana (Just my opinions)
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To: GeronL

Soon, soon...


8 posted on 04/17/2014 8:53:42 AM PDT by null and void (...if you are too sure of your place in heaven you might be too arrogant to actually get there.)
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To: null and void

I am of the opinion that within 20 years, medical science and 3d printing will be able to build replacement hearts, kidneys, livers, and possibly pancreas and lungs as well. Eyes, ears and brain tissue may take longer.

I understand that we can already produce bone, muscle, tendon, skin, intestine and veins.


9 posted on 04/17/2014 9:01:34 AM PDT by taxcontrol
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To: katana

They 3D printed LeeLoo (Milla Jovovich) in “Fifth Element” using only her gloved hand recovered from her crashed ship. She turned out very nicely.


10 posted on 04/17/2014 9:25:32 AM PDT by Flick Lives ("I can't believe it's not Fascism!")
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To: null and void

Well get on with it! I may need one at some point.


11 posted on 04/17/2014 10:00:22 AM PDT by ctdonath2 (Before you can find the right hill, someone will start watering trees. Prepare accordingly.)
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To: null and void

Tin Man is ecstatic.


12 posted on 04/17/2014 10:13:02 AM PDT by Rebelbase (Tagline: optional, printed after your name on post)
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To: null and void

And where are those kidneys I asked for!?

/sarc


13 posted on 04/17/2014 10:31:29 AM PDT by GeronL (Vote for Conservatives not for Republicans!)
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To: null and void

Check this out

http://www.digitaltrends.com/cool-tech/osteoid-3d-printed-cast-uses-ultrasound-heal-bones-40-faster/#!EPxk2


14 posted on 04/18/2014 3:15:16 PM PDT by Lurkina.n.Learnin
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To: null and void

No one has included the poisonous effect of ObamaCare.


15 posted on 04/18/2014 3:22:58 PM PDT by Balding_Eagle (Want to keep your doctor? Remove your Democrat Senator.)
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