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Researchers Who Provided Key Evidence For Gluten Sensitivity - Results Were False/Wrong
BI ^ | 5-8-2014 | Jennifer Welsh

Posted on 05/18/2014 8:43:16 AM PDT by blam

Researchers Who Provided Key Evidence For Gluten Sensitivity Have Now Thoroughly Shown That It Doesn't Exist

Jennifer Welsh
May 15, 2014, 3:37 PM

In one of the best examples of science working, a researcher who provided key evidence of (non-celiac disease) gluten sensitivity recently published follow-up papers that show the opposite.

The first follow-up paper came out last year in the journal Gastroenterology. Here's the backstory that makes us cheer:

The study was a follow up on a 2011 experiment in the lab of Peter Gibson at Monash University. The scientifically sound — but small — study found that gluten-containing diets can cause gastrointestinal distress in people without celiac disease, a well-known autoimmune disorder triggered by gluten.

They called this non-celiac gluten sensitivity.

Gluten is a protein composite found in wheat, barley, and other grains. It gives bread its chewiness and is often used as a meat substitute. If you've ever had "wheat meat," seitan, or mock duck at a Thai restaurant, that's gluten.

Gluten is a big industry: 30% of people want to eat less gluten. Sales of gluten-free products are estimated to hit $15 billion by 2016.

Although experts estimate that only 1% of Americans — about 3 million people — suffer from celiac disease, 18% of adults now buy gluten-free foods.

Since gluten is a protein found in any normal diet, Gibson was unsatisfied with his finding. He wanted to find out why the gluten seemed to be causing this reaction and if there could be something else going on. He therefore went to a scientifically rigorous extreme for his next experiment, a level not usually expected in nutrition studies.

For a follow-up paper, 37 self-identified gluten-sensitive patients were tested. According to Real Clear Science's Newton Blog, here's how the experiment went:

(snip)

(Excerpt) Read more at businessinsider.com ...


TOPICS: News/Current Events
KEYWORDS: dietandcuisine; food; gastrointestinal; gluten; glutensensitivity; grains
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1 posted on 05/18/2014 8:43:16 AM PDT by blam
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To: blam

Settled science.


2 posted on 05/18/2014 8:45:07 AM PDT by eartrumpet
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To: blam

For those, like myself, who avoid the terrible Business Insider website, here is a direct link to the study:

http://www.realclearscience.com/blog/2014/05/gluten_sensitivity_may_not_exist.html


3 posted on 05/18/2014 8:51:27 AM PDT by Blennos
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To: blam
Food fetishists.

/johnny

4 posted on 05/18/2014 9:02:25 AM PDT by JRandomFreeper (Gone Galt)
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To: blam

Thanks. I am always amazed at the food/diet trends, but this gluten thing is just stunning. Folks are just convinced that removing gluten will solve everything, including global warming (must have something to do with farting).

And now we have the person most responsible for this trend actually being a scientist and studying it further, and finding that his original report was pre-mature, and there is something else going on.

My mom used the get the Readers Digest disease-of-the-month. I look at this as the same psychosis.

Thanks for posting this.


5 posted on 05/18/2014 9:15:02 AM PDT by T. P. Pole
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To: Blennos

From your link;

” And last, but not least, nine days worth of urine and fecal matter would be collected. “

Uh,,,, kinda like “We have to pass it to see what’s in it.” Maybe Nan would like to be the study’s poop collector? Perfect job for her!


6 posted on 05/18/2014 9:25:37 AM PDT by Dr. Bogus Pachysandra ( Ya can't pick up a turd by the clean end!)
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To: blam

bttt


7 posted on 05/18/2014 9:25:44 AM PDT by ChildOfThe60s ((If you can remember the 60s.....you weren't really there)
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To: blam
Thanks for posting BLAM..... Coincidentally, some of the largest dietary sources of FODMAPs -- specifically bread products -- are removed when adopting a gluten-free diet, which could explain why the millions of people worldwide who swear by gluten-free diets feel better after going gluten-free...... [fermentable, poorly absorbed short-chain carbohydrates, also known as FODMAPs.]
8 posted on 05/18/2014 9:26:44 AM PDT by virgil283 ('No king .... but King Jesus')
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To: blam

I call total BS on this.

Celiac is a well-known, serious illness induced by allergy to gluten. And now these aholes are trying to say: well, either you’re 100% allergic to gluten or 0% allergic. You know, sort of like how everyone is either seriously allergic to various types of pollen or not allergic at all, with nothing in between. Oh, wait ....


9 posted on 05/18/2014 9:28:25 AM PDT by catnipman (Cat Nipman: Vote Republican in 2012 and only be called racist one more time!)
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To: blam

“Science. It works.”

HONEST science. IT works. Kudos to Gibson.


10 posted on 05/18/2014 9:30:01 AM PDT by aquila48
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To: blam
A scientist actually using the scientific method? Amazing!!!!!

I had a doctor that was convinced that every malady in the world could be traced either to Lyme's disease or to gluten. Whenever one of my tests came back negative, she'd order a different type of test for the same thing. I was tested for gluten sensitivity 17 times in 3 months, and for Lyme 9 times during that same period. My gluten test results never changed, but one of the Lyme tests eventually came back ambiguous, so she started me on high-powered antibiotics, which had no effect whatsoever so she kept upping the dosage. By the time I finally got fed up and refused to take anymore, I was hallucinating and my liver showed signs of giving out.

I'm a lot more skeptical these days.

11 posted on 05/18/2014 9:32:19 AM PDT by Ellendra ("Laws were most numerous when the Commonwealth was most corrupt." -Tacitus)
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To: Blennos

This study has decent controls including keeping
the FODMAP contribution isolated. After doing a decent
job on the basic test, the writer proceeds to display
a failure to search the literature for the causal
mechanism behind gluten sensitivity. There is plenty
to find. Try searching for zonulin and gliaden. The blogger
started with a preconceived result and did just enough
to try to give it a little support.


12 posted on 05/18/2014 9:34:44 AM PDT by Myrddin
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To: aquila48

I know, I’m the first to rail against “junk science”! But........I’ve had severe arthritis pain almost disappear for three years now, since I’ve given up Gluten (although I’m not a Nazi about it). I guess it could be placebo effect but three years is a long time. Whatever it is, I’m a little scared to go back full on to gluten.


13 posted on 05/18/2014 9:37:52 AM PDT by hulagirl (Mother Theresa was right)
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To: blam

I’m at the market last week — in produce section — and there is a sign that says “gluten-free” over the display of cut-up cantaloupe and watermelon in plastic containers. I laughed -but then went home to double check on internet to make sure there is no gluten in “fruit.”

Sure enough, No. But — get this — the article did say something like — “beware of cut-up fruit in bowls at the market unless you Know where it was cut up. It may have been “glutenized” if cut up in the Deli section as the Bakery section is usually right next to the Deli at market.”

Perhaps gluten is airborne.


14 posted on 05/18/2014 9:38:37 AM PDT by bunster
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To: bunster

“Gluten free” is the new “no trans fats” which was the new “carb free” which was the new “with oat bran”. Jiffy Pop for example now puts “gluten free!” on the bag of their one-ingredient product.


15 posted on 05/18/2014 9:42:18 AM PDT by jiggyboy
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To: blam

Gluten allergies are just another “look-at-me” fad. Man has been eating breads since the dawn of time and now we’re supposed to believe that thousands of people have suddenly developed allergies to its principal ingredient? Uh uh.

I’m sure some of these complaints are legitimate, but I’d guess the majority are hogwash.


16 posted on 05/18/2014 9:50:44 AM PDT by IronJack
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To: T. P. Pole

What was funny was that the tested people didn’t know which diet they were on, expected to feel bad, and as a result, did feel bad throughout all three tests, including the non-gluten one.


17 posted on 05/18/2014 9:58:42 AM PDT by Salvation ("With God all things are possible." Matthew 19:26)
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To: blam

Big Pharm can’t patent something that’s helping people, time to “debunk” it with their “studies”!


18 posted on 05/18/2014 9:58:57 AM PDT by goodwithagun (My gun has killed fewer people than Ted Kennedy's car.)
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To: blam
More crap science. People have been eating wheat, rye, and barley forever. There are always going to be some people allergic to something, in this case, celiac disease which is a minute percentage of the population. There are more people allergic to shell fish.

More stupid dog tricks, er, science facts:
1. The globe is heading towards a new ice age;
2. The population bomb will kill 10's of millions or even a billion;
3. Boys and girls are the same according to how they are raised (nature versus nurture). Oops, boys and girls have different brain pathways. Big surprise there for any parent or anyone who knows the simple process of hormones;
4. Thamaldahide (sp) will be the end of us all. Now it's considered a treatment for certain diseases;
5. The Ozone layer is disappearing and will kill us all. At 64, I'm still here;
6. Human industry CO2 output will kill Earth. The polar bears will die, yet more exist than ever. The Antarctic ice shelves are shrinking. Yet, certain places are increasing. Plus the Arctic has the biggest amount of ice in years. Where's the Northwest passage?;
7. Alaskan oil pipelines will kill the caribou. Yet, they flourish when hanging around said pipelines for warmth (seen the photos).
8. Einstein was right - Einstein was wrong according to current physicists;
9. Physicists know all until a new math theory pops up;
10. God doesn't exist. Then why can't the physicists explain their own "singularity" theory they propose about the ultra-condensed matter that exploded in the big bang?;
11. The universe is going to stop expanding because gravity will implode on itself. Now they say it will continue to expand forever. I actually feel sorry for astro-physicists because they have NO clue about what's behind this universe;
12. Dinosaurs went extinct because of an asteroid hitting somewhere in the Gulf of Mexico. Again unproven theory;
13. Marriage is an institution for all of any sex. No, marriage is an ancient idea of a union between a man and woman. Anything else is a simple contractual agreement;
14. Fish oil (omega 3 acids) are good for you. Now not so much;
15. Vitamin supplements are good for people with poor diets. Now they are a waste of money.
16. Eggs are bad, bad, bad. Now not so much;
17. Red meat is bad, bad, bad. Now not if limited in fat;
18. Cholesterol is what clogs your arteries. Now, it's tryglycerides and ANYTHING that causes inflammation of the interior walls of arteries;
19. Aspirin will cause stomach ulcers. Now may reduce heart and stroke attacks;
20. Statins were good...now bad;
21. Alcohol bad. Now, in moderation, very good;
22. Cancer incurable. Now treatable depending on the source;

I could go on and on about the absolutes the scientists have predicted.

Sad to say, I just don't trust scientists anymore like I used to when I was young. Seemed they were more into empirical evidence than their government funded studies. Still, the biological sciences have made found cures, treatments, and extended our lifespans. It's the junk science that I don't trust.

19 posted on 05/18/2014 10:00:41 AM PDT by A Navy Vet (An Oath is Forever!)
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To: jiggyboy

Like they label Red Vines licorice “Fat Free”. I get a chuckle out of that. 99% sugar, must be some kinda health food.


20 posted on 05/18/2014 10:01:57 AM PDT by Lurkina.n.Learnin
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To: IronJack

Some humans have been eating grain for about 1% of the species history. Some other humans do not process this foreign substance well.


21 posted on 05/18/2014 10:03:02 AM PDT by epluribus_2 (he had the best mom - ever.)
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To: catnipman
And now these aholes are trying to say: well, either you’re 100% allergic to gluten or 0% allergic

Did you miss the part of the results that show no difference between high, low and no gluten diets?

22 posted on 05/18/2014 10:11:45 AM PDT by palmer (There's someone in my lead but it's not me)
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To: epluribus_2
Some other humans do not process this foreign substance well.

Probably because of the way it is served giant quantities, overcooked and drowning in acidic slop like marinara sauce. Most humans can probably process grain when eaten naturally: raw, chewed thoroughly since it is raw, and eaten alone as an alternative to starvation since nothing else is available. Like most other diet maladies, the problem turns out to be culture not ingredients.

23 posted on 05/18/2014 10:16:36 AM PDT by palmer (There's someone in my lead but it's not me)
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To: A Navy Vet

The whole aim of practical politics is to keep the populace alarmed (and hence clamorous to be led to safety) by menacing it with an endless series of hobgoblins, all of them imaginary.

H. L. Mencken


24 posted on 05/18/2014 10:32:07 AM PDT by BwanaNdege ( "For those who have fought for it, Life bears a savor the protected will never know")
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To: catnipman

How many glutens are there? How many shapes and types of allergens are there? Allergy to gluten is like being allergic to Black Walnut pollen but not allergic to pine pollen. I know, that’s a hard thing to grasp, even if you’re not allergic to catnip but are allergic to cat dander.


25 posted on 05/18/2014 10:37:52 AM PDT by MHGinTN
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To: palmer
I've eaten raw grain. Grain has to be cooked if you want to avoid severe gastric distress.

/johnny

26 posted on 05/18/2014 10:37:52 AM PDT by JRandomFreeper (Gone Galt)
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To: A Navy Vet; blam
Oops, forgot:
The Earth is flat;
The Sun revolves around the Earth;

Really? about gluten? Other those few with the disease mentioned above, most complaints are probably from simple bloating and gas due to grain sensitivity. I probably keep Beano in business because I always have to take it before my raison bran in the morning or other grain products. So what? Jeeze, folks, buy a bottle of Beano - it's cheap. If that doesn't work, there is always Gas-X afterwards.

Here's my whine: I have to take Beano before I drink dark beer. Poor me.

Guess lactose intolerant folks have some kind of disease that just hasn't been properly funded and researched with an agenda.

I knew this whole gluten thing was BS, even told my wife who has to buy me Beano every week when grocery shopping. Again, proven correct.

27 posted on 05/18/2014 10:49:01 AM PDT by A Navy Vet (An Oath is Forever!)
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To: goodwithagun
"Big Pharm can’t patent something that’s helping people, time to “debunk” it with their “studies”!"

Actually, this study is correct. Try some Beano. It works for those of us who get bloated, gas, intestinal discomfort due to sensitivity to certain grains. Just try it before you eat grains. It's two little pills and will alleviate your gastro discomfort. It's a little hassle, but works. I now know others (aging population) who take Beano after long suffering gastro distress and glad the "big pharm" invented it. What do you think? Some guy in garage came up with a biological distress remedy?

Yes, "big pharm" is sometimes wrong and definitely charge too much in the US for some of their products. However, they spend billions of dollars for products that cure or relieve our ailments. My gripe is the same products are cheaper around the world. But then, that's capitalism. They spend the big bucks to research and go through the long complex FDA approval process, then they should get their investment back.

Just try it. Some products actually work.

28 posted on 05/18/2014 11:04:10 AM PDT by A Navy Vet (An Oath is Forever!)
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To: blam

I buy gluten free Bologna ,I think I get more Bologna


29 posted on 05/18/2014 11:06:34 AM PDT by molson209 (Blank)
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To: molson209
"I buy gluten free Bologna ,I think I get more Bologna"

I like gluten free cheeze.

30 posted on 05/18/2014 11:17:15 AM PDT by A Navy Vet (An Oath is Forever!)
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To: JRandomFreeper

I always order extra gluten.


31 posted on 05/18/2014 11:20:38 AM PDT by Lurker (Violence is rarely the answer. But when it is it is the only answer.)
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To: blam
This is a very confusing issue as are all allergies/sensitives. We are not all the same. What makes one person better, messes the next person up. Just get a copy of IBS For Dummies and check it out.
32 posted on 05/18/2014 11:23:27 AM PDT by Ditter
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To: Lurker
I eat whatever I want, whenever I want, and as how much as I want. It's worked for me, and I'm not a miserable person religiously checking labels.

I've got a life to live, I don't have time for a hobby like made-up food allergies.

/johnny

33 posted on 05/18/2014 11:32:36 AM PDT by JRandomFreeper (Gone Galt)
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To: palmer
"...chewed thoroughly..."

Please, ever heard of stomach acid? While it best to send your food down in smaller parts, you could eat a big enough "raw" piece of food and your stomach acid would still tear it apart. Although, admit it may give you a stomach ache or acid reflux. Still, the acid will desolve it enough to flow through the intestines.

BTW, although there are probably too many extra ingredients in our foods (most for preservation), "raw" food is a fallacy. People have been living longer and longer if they just eat a normal/balanced amount of even processed foods. That's not counting medical care.

34 posted on 05/18/2014 11:34:32 AM PDT by A Navy Vet (An Oath is Forever!)
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To: hulagirl

The best experiments are the the ones you do yourself on yourself, so if it works for you, even if it’s placebo, don’t worry about what anybody else says.

Although as humans we share many traits we also have may things that are unique to each one of us, so we do react differently to various things.

It’s interesting though that this study was about gastrointestinal problems, but you claim that it has helped you with your arthritis.


35 posted on 05/18/2014 11:50:14 AM PDT by aquila48
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To: Lurker
"I always order extra gluten."

YOU'RE GONNA DIE! Whole grains are now on the same level as butter or is it sugar or is red meat or is it steroid fed chickens or is it mercury in salmon or ... I forget.

Think I'll have a cigarette and some rum to think it over. It's 5 o'clock somewhere in the world.

36 posted on 05/18/2014 11:50:28 AM PDT by A Navy Vet (An Oath is Forever!)
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To: A Navy Vet

Why should people pop more pills, Beano or otherwise, when they can avoid eating certain things and feel great?

Are these the same scientists that put together Big Gov’s (insanely faulty) food pyramid?

People have been helping themselves using simple dietary adjustments like Docters Atkins and Agatson suggest, and they’re experiencing results beyond weight loss. Scientists tell us to avoid fat and cholesterol, yet on these diets cholesterol is lowered. Many docs are still selling that line when it turns out sugar is the culprit for high cholesterol, not cholesterol intake.

Some of us don’t like popping pills for problems, and would rather make dietary adjustments. If you want to pop pills be my guest, to each his/her own. I’m personally uncomfortable with Big Pharm’s passionate relationship with Big Gov. Too many pockets being lined.


37 posted on 05/18/2014 12:02:38 PM PDT by goodwithagun (My gun has killed fewer people than Ted Kennedy's car.)
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To: JRandomFreeper

I am very happy for you and your lack of allergies, some of us are not so lucky. I am 74 years old and in excellent health, the only problems I have had in my life were allergy related.

When my tongue swells up so big that I can’t keep it in my mouth or I have a blinding headache so bad my vision is affected I am not making anything up. How could I make up my face swelling or red hives around my middle?

I wish it would all go away and I could be as lucky as you but it doesn’t seem to be happening.


38 posted on 05/18/2014 12:12:53 PM PDT by Ditter
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To: Lurker

I love crusty bread, so the thought of living gluten free is abhorrent.


39 posted on 05/18/2014 12:24:02 PM PDT by Kozak ("It may be dangerous to be America's enemy, but to be America's friend is fatal" Henry Kissinger)
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To: blam

My sister was told by a quack doctor she had a gluten intolerance...after she had eaten the same way for nearly 60 years. My sister was gluten free all while dying of undiagnosed kidney cancer, nearly two years. I guess a gluten free diet does not treat kidney cancer. I am still very angry and feel that stupidity killed my sister. She had symptoms of something being wrong, and it was cancer. When she finally got really sick her husband took her to the ER and they were able to diagnose her kidney cancer in a matter of hours. The quack doctor had no clue.


40 posted on 05/18/2014 12:58:07 PM PDT by Tammy8
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To: goodwithagun
No problem if people want to avoid foods that create problems...their choice. Just letting people who enjoy grains, there is an inexpensive remedy.

Atkins is low carb diet. So what about people who like high glycemic carbs as in grains?

You're preaching to the choir about the gov food pyramid.

As for cholesterol, see my one of my points in the long message above that nutritionists/doctors now believe it's about tryglicerides and other inflammatory intake that causes problems in the endothelium. BTW, CoQ-10 is probably one of the best heart/plaque supplements you can take - for now...as if my point about ever changing nutrition recommendations.

41 posted on 05/18/2014 1:05:45 PM PDT by A Navy Vet (An Oath is Forever!)
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To: Tammy8

My sister-in-law was told by a doc, physical therapist, and pain management specialist that her chronic back pain could be relieved with a pill that lists cancer as a side effect and surgery if the pill doesn’t work. She did a quick low-carb diet for the first time ever to lose a few pounds before a Florida wedding. Her back pain disappeared. When she got home from the wedding with no food in the house, she made a pb&j with bread from the freezer. That night her pain started to come back. A coworker suggested that perhaps her issues were gluten related. Skeptical, she tried an elimination diet, and was in pain again when she tried adding gluten back.

Her quack doc, quack pt, and quack pain management specialist weren’t too happy with her, especially after the doc tested her and found that she doesn’t have gluten issues. She knows what makes her pain go away, and it’s not the cancer causing pills the quacks were pushing, it’s avoiding gluten. She’s a much happier person now.


42 posted on 05/18/2014 1:15:21 PM PDT by goodwithagun (My gun has killed fewer people than Ted Kennedy's car.)
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To: T. P. Pole
Thanks. I am always amazed at the food/diet trends, but this gluten thing is just stunning. Folks are just convinced that removing gluten will solve everything, including global warming (must have something to do with farting).

The other day Bill O'Reilly said he was healthier on his gluten free diet. Bread is the staff of life that has supported Western Civilization for centuries. If gluten intolerance was real how did we ever get to where we are? I could see a few people being this way. But not millions and millions

43 posted on 05/18/2014 1:20:20 PM PDT by dennisw (The first principle is to find out who you are then you can achieve anything -- Buddhist monk)
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To: eartrumpet

Eh, I dunno. I’ve been gluten intolerant for about 5 years. I’ve done many “experiments” on my own. It all comes down to the fact that if I eat gluten bad things happen. So life goes on I suppose.


44 posted on 05/18/2014 1:37:23 PM PDT by RFEngineer
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To: goodwithagun
I have a similar story as your sister in law. After eating bread all my life (I am old) with no problem about 3 or 4 years ago I realized that when I ate bagels I got constipated.

I gave up bagels and all was well. I was checked for gluten sensitivity and was told I was not gluten sensitive.

After 2 trips to the ER with severe infection in my colon it became apparent that any kind of bread was the culprit. If some of you refuse to believe me.......... bless your hearts! :)

45 posted on 05/18/2014 1:38:11 PM PDT by Ditter
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To: epluribus_2

“Foreign substance”???

I can’t think of anything that’s LESS of a foreign substance than wheat flour ... unless it’s air or water.


46 posted on 05/18/2014 1:47:44 PM PDT by IronJack
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To: dennisw
Bread is the staff of life that has supported Western Civilization for centuries. If gluten intolerance was real how did we ever get to where we are?

The Wheat Belly guy (Dr. William Davis) says that today's high-yield hybrid wheat is not what has been eaten for centuries.

47 posted on 05/18/2014 2:08:26 PM PDT by Overtaxed
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To: hulagirl

My wife has been gluten free for close to a year now;no more swollen joints or joint pain and no more medication. If she eats corn chips or anything with flour or wheat in it, the next morning, she has very painful and swollen joints.....Read ,”Wheat Belly”. The wheat we eat today is not the same as it was 30 to 40 years ago. Today it is genetically modified to be resistant. to drought and even pesticides, to produce more. So what if genetically modified seeds can cause an auto-immune reaction in our body?


48 posted on 05/18/2014 2:39:37 PM PDT by rxtn41
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To: catnipman
Celiac is a well-known, serious illness induced by allergy to gluten. And now these aholes are trying to say: well, either you’re 100% allergic to gluten or 0% allergic. You know, sort of like how everyone is either seriously allergic to various types of pollen or not allergic at all, with nothing in between. Oh, wait ....

The study questioned non-celiac gluten sensitivity. It doesn't question the reality, or seriousness, of celiac disease (which, by the way, is not caused by allergy).

49 posted on 05/18/2014 3:05:40 PM PDT by RansomOttawa (tm)
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To: Ditter

My sister-in-law was quite skeptical, but was in enough pain to give it a shot. Her husband has chosen to go gluten free as well. He doesn’t have any health issues, but seeing what it did for his wife was an eye opener. Most of my husband’s family is in the medical field and really don’t approve of such things. The look on my mother-in-law’s face was priceless when I told her I was doing acupuncture for my pregnancy pain.


50 posted on 05/18/2014 4:23:51 PM PDT by goodwithagun (My gun has killed fewer people than Ted Kennedy's car.)
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