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Why That Observational Study of Hydroxychloroquine in The Lancet Seems Fishy
The Wire ^ | June 2, 2020 | Peter ellis

Posted on 06/03/2020 1:19:57 PM PDT by absalom01

If you’re following at all the search for COVID-19 treatments, and possibly even if not, you will have seen the flurry of media coverage for the observational study in The Lancet, ‘Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis’. It made the news not least because hydroxychloroquine is the drug President Donald Trump says he is taking in the belief that it will reduce his chance of catching COVID-19. ...

The data in that study, and in at least one preprint on a second treatment, were provided by an Illinois firm called Surgisphere. Allegedly the data represents the treatment and health outcomes of 96,032 patients from 671 hospitals in six continents. However, there is simply no plausible way I can think of that the data are real.

(Excerpt) Read more at science.thewire.in ...


TOPICS: Business/Economy; Foreign Affairs; Government; News/Current Events
KEYWORDS: ccpvirus; chicombioweapon; covid19
Some more discussion of the Lancet study and why it's probably garbage.
1 posted on 06/03/2020 1:19:57 PM PDT by absalom01
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To: absalom01

We don’t need to do a ‘study’...
HCQ is one of the top 200 drugs prescribed annually.

Just find out if ANY of those people got sick with COVID


2 posted on 06/03/2020 1:24:24 PM PDT by Mr. K (No consequence of repealing obamacare is worse than obamacare itself.)
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To: Mr. K

Well, if you remember the dustup over the Lancet study, it stopped randomized trials using HCQ and AZT. It appears to be a deliberate fabrication at this point.

Why? The Zelenko Protocol appears to work based on observational data. That’s a problem, because the entire course of treatment costs less than 20 bucks, and is available worldwide. That is a huge problem for some people.


3 posted on 06/03/2020 1:28:18 PM PDT by absalom01 (You should do your duty in all things. You cannot do more, and you should never wish to do less.)
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To: absalom01

Other than:

- thousands upon thousands of successful uses of Hydroxychloroquine.
-ZERO negative reactions or side effects
?

Or maybe we just need to follow the $$$$$$


4 posted on 06/03/2020 1:33:09 PM PDT by TheBattman (Democrats-Progressives-Marxists-Socialists - redundant labels.)
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To: Mr. K
But what about the lupus patients? Said a dr I know... I do not think the average citizen fully comprehends how political the scientific methodology literally is. Humans played in a lab and discovered ‘gain of function’, and then labeled it COVID-19... the world became their gain of function, for fame, prosperity, and death, destruction, and limited control... Of productive healthy humans..

Anybody seen Dr. Fauci out warning about lack of social distancing in gangs of looters? Will Q-Mo send the looters to the now vacant beds in nursing homes?

5 posted on 06/03/2020 1:35:21 PM PDT by Just mythoughts (Psalm 2. Why do the heathen rage, and the people imagine a vain thing?)
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To: TheBattman

NEJM is publishing a Minnesota study that used HCQ and AZT, with zinc added to 20% of patients, with early prescription.

Zelenko publishing his own results in a couple of weeks.

It’s both the money and the political football. The desire to “get Trump” outweighs the desire for a working treatment. Same as the riots. There is nothing, nothing at all, that the left/Dem/globalist alliance will not do. They simply don’t care how many people have to die, or what institutions have to be destroyed for them to regain full power.


6 posted on 06/03/2020 1:37:03 PM PDT by absalom01 (You should do your duty in all things. You cannot do more, and you should never wish to do less.)
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To: absalom01

Even The Lancet is starting to walk back that study.

http://www.freerepublic.com/focus/news/3851378/posts?page=8#8

Good thread with lots of quality recent papers / links, besides that one.


7 posted on 06/03/2020 1:42:23 PM PDT by FreedomPoster (Islam delenda est)
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To: absalom01

Interesting, here’s another -
“Governments and WHO changed Covid-19 policy based on suspect data from tiny US company -

A Guardian investigation can reveal the US-based company Surgisphere, whose handful of employees appear to include a science fiction writer and an adult-content model, has provided data for multiple studies on Covid-19 co-authored by its chief executive, but has so far failed to adequately explain its data or methodology.

Data it claims to have legitimately obtained from more than a thousand hospitals worldwide formed the basis of scientific articles that have led to changes in Covid-19 treatment policies in Latin American countries. It was also behind a decision by the WHO and research institutes around the world to halt trials of the controversial drug hydroxychloroquine.” https://www.msn.com/en-gb/news/coronavirus/governments-and-who-changed-covid-19-policy-based-on-suspect-data-from-tiny-us-company/ar-BB14Y495


8 posted on 06/03/2020 1:44:00 PM PDT by Varda
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To: absalom01

Because it is fishy. So fishy, we’re gonna need a bigger boat. If the drug was dangerous, we’d have known decades ago. It isn’t. Follow the money.


9 posted on 06/03/2020 1:54:58 PM PDT by bgill (Idiots. CDC site doesn't recommend wearing a mask to protect from COVID-19)
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There is absolutely no limit how suffering and harm democrats are prepared to inflict on their constituents for absolutely no reason other than to score some imaginary point against Trump. I think th le democrats paid the Chinese To spread the virus to take out the economy. The timing of its arrival right in time for the democrats desperate for anything to destroy the economy is just a wee bit too coincidental


10 posted on 06/03/2020 2:02:53 PM PDT by dsrtsage (Complexity is merely simplicity lacking imagination)
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To: Mr. K

Some on HQC did catch the disease, from what I hear. It may have some use as prophylaxis in some people but there is no study I know of. It would be a difficult study to conduct.

But they are missing the point. I heard Cuomo say that 80% of people put on ventilators die. And he was demanding 40,000 of them! If the statistics are right, there is no way to say that ventilators help at all and you could argue they actually harm more people than they help. No way to know because there is no ‘controlled study’ but if 80% die it is fairly certain ventilators provide no statistically significant benefit.

The data that is out there strongly suggests that HQC + Zinc (or maybe Copper) + Azithromycin (or Erythromycin for certain CV impaired people) works IF GIVEN EARLY. Giving it to people who are already in the ICU is probably just as unlikely to show a statistically significant benefit as a ventilator.

What is needed is a way to knock the virus back on its heels before it overwhelms, as soon as diagnoses or at first sign of symptom, so that the human body has time to build its own immunoresponse. That takes time so a treatment regimen that buys the body time is the one that is most likely to work. The 2 drug plus 1 mineral regimen seems to do exactly that by altering blood pH, preventing infection, and blocking the cell receptors that the virus binds to. And it’s short term. I would be afraid of a vaccine that permanently binds to blood cell receptors needed for uptake of minerals in general. The science behind the regimen is “anecdotal” but that doesn’t mean it isn’t true. There is data out there, just not all in the same controlled study but a post hoc reading of the various doctors/centers using this cocktail seems to show a massively lower mortality rate than the standard of care statistics.

And those 2 drugs, plus one mineral, are widely used and generally safe. And cheap as heck generics. There is essentially no risk in taking them upon diagnoses or onset of symptoms.

It’s sad, actually, that so few people have actually questioned the appropriateness of ventilators. It seems that the real cause of death is due to oxygen deprivation. Infection in the lungs restricts oxygen uptake to the bloodstream, which will lead to one of many types of death such as organ failure, pneumonia, heart attack/stroke, etc. No amount of ventilator is likely to help - you can push all the air you want into the lungs it won’t matter if the oxygen can’t get into the bloodstream. The whole point of the 2 drug + 1 mineral regimen is to prevent the virus from replicating, prevent infection, and avoid hospitalization, ventilators, cytostorms, and death. That’s gonna be cheaper and easier than some wished-for “vaccine”.

It certainly does seem that there is way too much politics injected into this debate. First, because some of the early research got to Trump many people reflexively wanted to reject it out of hand. It’s not like Trump invented it! He just spoke about it first to a worldwide audience and the Trump haters immediately poo-poo’d it. Then, Trump bashed the WHO, so the WHO tried to put the kibosh on any study; designing them to fail. Again, giving the drug(s) to people who are already knocking on heaven’s door is going to fail. It’s got to be given early.


11 posted on 06/03/2020 2:27:53 PM PDT by monkeyshine (live and let live is dead)
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To: absalom01

Yep - two HUGE factors go into this:

1. GET TRUMP (the man who was an early cheerleader for HCQ) - cannot have him proven correct, even if he was correct. That isn’t politically expedient.

2. Follow the $$$$$$$$$$$$$. The maker of Remdesivir, Gilead Sciences, has $Billions riding on it - and Dr. Fauci is... imagine this... financially invested.

HCQ is way beyond patent - so is FAR FAR less profitable.


12 posted on 06/03/2020 2:48:35 PM PDT by TheBattman (Democrats-Progressives-Marxists-Socialists - redundant labels.)
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To: absalom01

The Lancet is soon to acquire the same credibility as CNN .... fake news and fake medicine.


13 posted on 06/03/2020 3:22:40 PM PDT by RetiredTexasVet
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To: absalom01

They restarted the study that WHO shut down.


14 posted on 06/03/2020 3:29:29 PM PDT by Sacajaweau
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