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Diabetes, Spinal Cord and Brain Injury - Molecular Switch Found
Culture of Life Foundation | September 14, 2001

Posted on 09/14/2001 6:18:46 PM PDT by Slyfox

Washington: In the wake of the terrible tragedies this week, we see with even greater clarity the limitless worth of every human life. Every person's life is truly unique, sacred, and inviolable, and to take an innocent life for any reason is an evil act. Continuing moral paths of scientific research show us that at no point should one kill another human being, no matter how small, even for the purposes of curing another. This means specifically, embryonic and fetal human beings. Likewise, it is not morally licit to use their cells if they have been already killed. Progress with adult stem cells and with research involving no stem cells from any source continues to point the way toward cures that are both morally acceptable and effective.

This week two breakthroughs were announced, against diabetes and spinal cord and brain injury, and no embryonic or fetal stem cells were used in either.

New Hope for Diabetes Patients: Molecular Switch Discovered For Regulation Of Glucose Researchers at the Dana Farber Cancer Institute in Boston, the University of Texas Southwestern Medical Center in Dallas, and the Harvard Medical School have found a long-sought molecular switch which regulates the production of glucose. The finding bodes well for sufferers of diabetes, since it will greatly help in designing new drugs to target the protein involved. The protein is called PGC-1, and it is normally active in liver cells, and plays a role in upregulating the production of glucose in the body. Normally, it works with the protein insulin to keep blood sugar at normal levels.

In diabetics, insulin can be lacking or ineffective, causing serious problems with blood sugar levels. The key protein PGC-1 was previously found to become more active in the muscles and fat of mice that were exposed to cold temperatures. This caused the scientists to wonder if it played a role in the production of glucose, so they inserted the gene for PGC-1 into mice using a harmless viral vector (virus which doesn't cause disease, which has been designed to carry the desired gene into the animal's body), and the gene indeed caused the mice to become hyperglycemic (excess of sugar in the blood).

One of the scientists involved called this a "real eureka moment." The scientists believe that this new finding could help in the treatment of diabetes, by allowing researchers to design drugs to turn down glucose production in diabetics by targeting this protein. This is yet another finding in the research of diabetes which shows that there is no need to resort to the use of human embryonic or fetal cells in the treatment of this disease. Sources: Sept. 13, 2001 issue of Nature Spinal Cord and Brain Injury/Disease

Neuron and Microchip Combination Could Help Treat and Understand Spinal Cord and Brain Injury/Disease

Scientists at the Max Planck Institute for Biochemistry in Munich have designed one of the first conducting "nerve chips", which is a combination of live neurons and silicon. They utilized snail neurons and tiny silicon pegs (which help separate the neurons) on a chip, and applied electrical impulses to the chip. The impulses passed from one neuron to another, and back to the chip to form a live circuit. Although true "neurocomputers" are a long way off, this is a step towards being able to understand brain circuitry better, and to possibly build biosensors (for use in testing pharmaceutical drugs on nerve cells) or neuroprosthetic devices that could help treat spinal cord injury or brain diseases. For example, a "biochip" could be used to "bridge a damaged section of the spinal cord" (see Source). Such amazing developments preclude any imagined need for utilitarian research on human embryonic stem cells or fetal cells. Source

TOPICS: Breaking News; Culture/Society; News/Current Events
Can't let this good news be hidden under our recent tragedy.
1 posted on 09/14/2001 6:18:46 PM PDT by Slyfox
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To: Slyfox
Bump for life.
2 posted on 09/14/2001 6:26:10 PM PDT by Moonlight Graham
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To: Moonlight Graham
OH My GOD! It's coming. The chip is here--they created the massive diabetes epidemic with the food pyramid and low fat diet farce and now they are going to cure it by implanting us with chips. YES.
3 posted on 09/14/2001 6:44:28 PM PDT by Germanflower
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To: Slyfox
Out of a week of unprecedented death comes a gift of life to the world, from America.
4 posted on 09/14/2001 6:46:34 PM PDT by Physicist (
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To: Germanflower
Your sarcasm is not appreciated.
5 posted on 09/14/2001 6:48:51 PM PDT by Slyfox
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To: Slyfox - MarMema - COB1 - wattsmag2 - Freedom'sWorthIt
Bless you for posting this, Slyfox!
As a very brittle diabetic of 28 years, with wide-ranging and life-threatening blood glucose values, this is joyous news!

Even working in a hospital with constant supervision - insulin infusion pump for 9 years - nothing works to achieve even a modicum of control.
I have always had frequent insulin reactions, many in the 30's and below - was 'LO" just the other night again - meaning the meter could not register it because it was below 25.
God holds me together and I pick myself up and go on - but to think of being free of this hell??
Yes - welcome news indeed!!
Thank you.

6 posted on 09/14/2001 6:57:47 PM PDT by LadyX
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To: LadyX
I rejoice with you at this good news....especially at this time. I have 2 friends with diabetes and I know they will be estatic at this breakthrough. Best wishes here for the light at the end of this tunnel for you and other diabetics.
7 posted on 09/14/2001 7:12:53 PM PDT by Carolinamom
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Comment #8 Removed by Moderator

To: Germanflower
LOL - so funny.
9 posted on 09/14/2001 7:26:19 PM PDT by ClancyJ
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To: Carolinamom
Thank you, Carolinamom.
Diabetics with a mild form are fortunate compared with the quirks of mine, and only a loving God has held me together!
I was supposed to die 15 years ago from the kidney complications, but HE formed them - and controls them STILL!
I have miles to go yet for Him...
10 posted on 09/14/2001 8:17:11 PM PDT by LadyX
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To: Germanflower
As a diabetic, I find your efforts at joviality very offensive. You should be ashamed of yourself and pray to God that YOU don't come down with some immune-deficiency disease.
11 posted on 09/15/2001 4:54:21 AM PDT by JudyB1938
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To: Slyfox
Bump so this thread may be read by others.
12 posted on 09/15/2001 8:23:05 AM PDT by Slyfox
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To: Slyfox
I thank you for this news... there are so many who may benefit from these lines of research.
13 posted on 09/15/2001 8:39:28 AM PDT by backhoe
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To: LadyX
I hope this work effects a cure for you Mom. My prayers toward that end.
14 posted on 09/16/2001 9:37:05 AM PDT by wattsmag2
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To: wattsmag2
Thanks, Son...the power of prayer is mighty!
15 posted on 09/16/2001 10:24:31 AM PDT by LadyX
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To: all
I'm not being sarcastic. Stop eating sugar and fruit and refined foods including flour, pasta, rice, bread...they are not good for anyone despite the government telling you for the past umpteen years to consume 11 servings of this garbage. The diabetes epidemic has been no accident. Take a look at the glycemic index, if it hasn't already been censored. Look at the mountains of research out there that proves this. Or stuff the oat bran muffin and wonder why your sugar is reading 350. I personally do not like the idea of neuro-implantation. I do not mind offending you, that stuff is for emotional junkies. Nor am I offended. Wait till every lard butt in the country has an implant, it will be the new prozac. I bet you get a years supply of low-fat chocolate chip cookies with that.
16 posted on 09/20/2001 4:45:14 PM PDT by Germanflower
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To: Germanflower

Atkins was right all along with his views on syndrome x and hyperinsulinism in regard to adult-onset, type II diabetes. It was recently published that even one soda per day can lead to diabetes in women.

17 posted on 09/22/2004 9:39:50 PM PDT by Coleus (Roe v. Wade and Endangered Species Act both passed in 1973, Murder Babies/save trees, birds, algae)
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