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Very Heavy Pot Use Clouds Mental Function: Study
Yahoo News ^ | 11/29/02 | Very Heavy Pot Use Clouds Mental Function: Study

Posted on 11/29/2002 2:18:13 PM PST by Libloather

Very Heavy Pot Use Clouds Mental Function: Study
1 hour, 58 minutes ago
By Dana Frisch

NEW YORK (Reuters Health) - People who smoked unusually large amounts of marijuana performed worse on tests of mental function than their peers who smoked less pot, even after a 30-day abstinence period, according to a new report.

Heavy users performed worse on 69% of the 35 tasks than light users, though their performances were not "clinically abnormal," the researchers found. The 22 participants were admitted to hospital during the course of the study and submitted to random urine tests to ensure they remained abstinent.

Lead author Dr. Karen Bolla characterized the study group as being "unusual" because of the large number of joints they smoked per week. Heavy users smoked on average 91 joints a week, or about 13 a day, while light smokers smoked an average of 11 marijuana cigarettes a week.

Bolla, who is an associate professor of neurology and psychiatry at Johns Hopkins University School of Medicine in Baltimore, Maryland, said the results cannot be generalized to social smokers or those who use pot for medicinal purposes, because they smoke far less marijuana. The potency might also differ, she said.

"What this study shows is that marijuana can be neurotoxic if you smoke a lot of it," Bolla told Reuters Health. She said this is particularly concerning since the average age of study participants was 22 years old, and the brain is still developing at that age. "You're putting a lot of foreign stuff in there that we don't really know what it does to a developing brain," she said.

The study, published in the November issue of the journal Neurology, found that the mental functions most severely impacted were memory, executive function (overall reasoning and functioning) and manual dexterity.

Bolla writes that these tasks in particular were affected because they are controlled by the hippocampus, prefrontal cortex and cerebellum. These brain areas are densely populated with cannabinoid receptors that attach to THC, the active ingredient in marijuana.

In mice, excessive marijuana use might damage parts of the brain and "knock out certain kinds of neurons," said Bolla. This can lead to receptors in the brain being over-stimulated or under-stimulated, changing their response to chemical messengers in the brain, similar to what might result from a brain injury.

Marijuana is the most widely used illicit drug in the US. An estimated 7 million people use marijuana weekly, according to 2000 data from the US Department of Health and Human Services.

This is only the second study to examine the residual effects of marijuana use after more than a couple of days of abstinence. Dr. Harrison Pope Jr., a professor of psychiatry at Harvard Medical School and author of the other study, found no difference in performance on cognitive tests between heavy marijuana users and "control" subjects.

Pope said in an interview that his "hunch" was that the difference between his results and Bolla's were the "sheer intensity" of marijuana use among the participants in Bolla's study. Heavy users in Pope's study smoked on average 1 or 1.5 joints over the course of a day.

According to Pope, people who smoke a lot of marijuana and start earlier will do worse on tests of mental function. Whether the toxicity of the drug itself is responsible, or factors like being in school less and being unfamiliar with testing or being more impaired initially and turning to pot for that reason, is difficult to know, he added.

SOURCE: Neurology 2002;59:1337-1343.


TOPICS: Culture/Society; Extended News
KEYWORDS: antipotconspiracy; brownshirts; dudeilostmybong; dumembers; function; ganja; getdumb; heavy; jbtsonparade; libertines; lpvoters; mental; potuseclouds; stonerssuck; study
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In mice, excessive marijuana use might damage parts of the brain...

Let me make this perfectly clear - I've never ONCE called Liberteens - mice...

1 posted on 11/29/2002 2:18:14 PM PST by Libloather
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To: Libloather
Oh, look, Ma! Another thread about pot!

How exciting!

2 posted on 11/29/2002 2:19:16 PM PST by Glenn
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To: Libloather
I personally will NEVER FORGET...

.."I wonder what Great Dane tastes like, Man"...?

...from CHEECH -&- CHONG's...

.."UP in SMOKE"


3 posted on 11/29/2002 2:22:51 PM PST by ALOHA RONNIE
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To: Libloather
Lead author Dr. Karen Bolla characterized the study group as being "unusual" because of the large number of joints they smoked per week. Heavy users smoked on average 91 joints a week, or about 13 a day, while light smokers smoked an average of 11 marijuana cigarettes a week.

Puh-LEEZE! This is like one of those studies that found that saccharin causes cancer--if you drink a bathtub of it a day. They should give a medal to anyone whose lungs could stand 13 joints a day!

4 posted on 11/29/2002 2:22:58 PM PST by Bob Quixote
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To: Libloather
Sorry. I forgot what I wanted to say about this article.

(Was I finished?)
5 posted on 11/29/2002 2:23:20 PM PST by Maceman
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To: Libloather
I've never ONCE called Liberteens - mice...

You know what Libertarians are good for don't you?

Neither does anyone else.

6 posted on 11/29/2002 2:24:41 PM PST by Common Tator
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To: Libloather
I hope you have your flame suit on because the LIBERALtarians will be here any moment now. BTW: This ain't news. And I've added some keywords for you.
7 posted on 11/29/2002 2:25:24 PM PST by Sparta
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To: Libloather
Well, that's one little mystery solved...


8 posted on 11/29/2002 2:25:30 PM PST by Paul Atreides
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To: Maceman
What?
9 posted on 11/29/2002 2:26:31 PM PST by vnix
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To: Libloather
Duh!!
10 posted on 11/29/2002 2:28:21 PM PST by jgrubbs
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To: Libloather
Hold My Roach Alert
11 posted on 11/29/2002 2:28:54 PM PST by joesnuffy
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To: jgrubbs
Duh!!

Is that some more proof?

12 posted on 11/29/2002 2:30:29 PM PST by Libloather
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To: Libloather
91 joints a week? what did these guy's eat, 200 bags of Cheeto's a week.

BTW wonder what the result would be if the subjects drank 91 sixpacks a week, or 21 bottles of Jack Daniels per week?
13 posted on 11/29/2002 2:30:43 PM PST by Leto
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To: Libloather
You know that's not........................................ ...........................................................
...........................................................
...........................................................
...........................................................
............................................uh never mind.
14 posted on 11/29/2002 2:33:27 PM PST by menotyu
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To: Glenn
Oh, look, Ma! Another thread about pot!

How exciting!

Close. It's another article about pot, with another thread about libertarians. Somewhere, Pavlov is smiling.

15 posted on 11/29/2002 2:33:40 PM PST by tacticalogic
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To: Maceman
LOL! What was I going to say? I forgot to remember.
16 posted on 11/29/2002 2:33:43 PM PST by slimer
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To: Leto
The result of 21 bottles of Jack Daniels a week??...I'd haffta say........Depends®
17 posted on 11/29/2002 2:36:15 PM PST by Nekman
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To: Leto
BTW wonder what the result would be if the subjects drank 91 sixpacks a week, or 21 bottles of Jack Daniels per week?

I would think that they would perform somewhat less well on simple diagnostic tests than the control group.

18 posted on 11/29/2002 2:36:16 PM PST by Trailerpark Badass
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To: slimer
Like, hey, man, er, uh, you know, like, er, hey, awesome.
19 posted on 11/29/2002 2:36:56 PM PST by ofMagog
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To: Wolfie; vin-one; WindMinstrel; headsonpikes; philman_36; Beach_Babe; jenny65; AUgrad; Xenalyte; ...
WOD Ping
20 posted on 11/29/2002 2:38:44 PM PST by jmc813
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To: ofMagog
Like, hey, man, er, uh, you know, like, er, hey, awesome.

It's not er, it's 'ere!.

21 posted on 11/29/2002 2:40:03 PM PST by tacticalogic
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To: Libloather
Heavy users performed worse on 69% of the 35 tasks than light users, though their performances were not "clinically abnormal," the researchers found.

So, I would imagine that this means that the Super Fiends performed better on 31% of the tasks?

22 posted on 11/29/2002 2:41:39 PM PST by Trailerpark Badass
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To: ofMagog
Wow man, that's heavy! ;>)
23 posted on 11/29/2002 2:46:32 PM PST by slimer
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To: Libloather
I have smoked pot since I was 12. I have known a LOT of "Stoners" and even more regular smokers (Like me). During college in the 80's, I saw more drugs and was around more drug abusers than anyone I know.

That being said...

I have NEVER known ANYONE to smoke THIRTEEN FREAKING JOINTS A DAY ON AVERAGE!!!

Yeah, I have seen people (Including myself) smoke 13 joints in a day (Actually, that's not even true...The joints were shared so the total amount of jointage is considerably less) but nothing even CLOSE to an average of 13 joints a day.

Now...Maybe back in the 70's and before, people regularly did this because the pot was about as potent as an aspirin, but since the introduction of high THC pot (Early 80's), NO ONE is smoking 13 a day. Hell, even 11 a week is a LOT!!

This study is a joke.

24 posted on 11/29/2002 2:50:32 PM PST by Johnny Shear
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To: Libloather
"Very Heavy Pot Use Clouds Mental Function: Study"

The Evidence

25 posted on 11/29/2002 2:53:21 PM PST by HumanaeVitae
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To: Libloather
I had to cut down on my pot use in law school to the bare minimum, and in fact thereafter. Quite annoying, but it really did impair performance. Really. And even after "recovery" things were sort of sluggish. Really. Frankly, you can't read a paragraph when stoned and remember the beginning by the time you get to the end. About the only thing I could do in that state was math problems (and one doesn't do math problems in law school). Odd.
26 posted on 11/29/2002 2:53:32 PM PST by Torie
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Comment #27 Removed by Moderator

To: Bob Quixote
I have seen dreads smoke that much. I could never keep up back in those days when.....

What was this thread about again?
28 posted on 11/29/2002 2:59:17 PM PST by wardaddy
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To: Libloather
Very Heavy Pot Use Clouds Mental Function: Study

Incarceration Clouds Mental, Physical, and Spiritual Function: Reality.

29 posted on 11/29/2002 3:03:09 PM PST by coloradan
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To: Johnny Shear
The article speaks of those who are "very heavy" smokers. Not "average smokers," not "heavy smokers," but "very heavy smokers."

Jah, mon, I and I ask your iree Rastaman abou' dis.


30 posted on 11/29/2002 3:05:56 PM PST by FreedomCalls
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To: Libloather
"I've never ONCE called Liberteens - mice..."

And I've never called conservatives simpleton morons. So what's your point?

I assume you have access to cans of hair spray. Do you sniff it everyday just because you could if you wanted too? Apparently you guys believe no one has any self control at all, so therefore there should be a law against anything that some stupid arse might shove up his nose. Therefore we should ban Chlorox, amonia, sleeping pills, carrots, peas, aspirin - in fact anything and everything that can be abused.

31 posted on 11/29/2002 3:08:01 PM PST by FastCoyote
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To: Torie
Is marijuana addictive? Are there any withdrawl problems going cold turkey? Is it easier to quit than smoking?
32 posted on 11/29/2002 3:08:08 PM PST by CWRWinger
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To: Johnny Shear
Johnny, how old are you?

I smoked the evolution of pot myself personally. From sh!tty Mex brick weed in 1971 to good Colombian and Jamaican that started coming around in 1973/74....then it was Oxacan foxtail/wife beater long lime green buds (not too shabby) around 1975/76 and then the grand arrival of the first SENSE around summer of 1977 and onwards....sticky skunk bud. I remember my first sensemilla joint....it got 4 or 5 folks buzzed and it lasted longer than usual.

Yes indeed, there was decent pot around in the 70s my man...and lots of black hash as well and honey or red hash oil too. All very very stone-worthy. There was always lots of seedless Thai around as well.

No doubt that hydro pot today has reached esoteric dimensions but good skunk and even good sativa was avaliable as early as the mid 70s.

I gave it up around 82 or 83....life got in the way but i still take a peek at my little brother's weed from time to time. It's great but not exponentially better.
33 posted on 11/29/2002 3:09:44 PM PST by wardaddy
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To: FreedomCalls
450 pound bales of marijuana, when placed on people, cause difficulty breathing and may lead to death.
34 posted on 11/29/2002 3:10:14 PM PST by coloradan
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To: Bob Quixote
They should give a medal to anyone whose lungs could stand 13 joints a day!

I know someone who should get a medal then. It really isn't that difficult if you start when you first wake-up in the morning and keep going until you go to sleep at night.

35 posted on 11/29/2002 3:13:33 PM PST by FourPeas
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To: coloradan
Actually, incarceration provides a clarity unmatched by much outside of combat.
36 posted on 11/29/2002 3:14:08 PM PST by wardaddy
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To: ALOHA RONNIE
Dave? Open up the door man, it's ME...DAVE!

It's Officer O'Malley and YOUR'E BUSTED...

The most often used word in the English Language: "'ere"...

ELO and Boston, both sides = one party bowl

37 posted on 11/29/2002 3:15:08 PM PST by GRRRRR
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To: Libloather
This article belongs in the "Duh!" category. Excessive eating causes obesity. Excessive promiscuity leads to STD's. Excessive drinking of alcohol leads to liver problems. Excessive spending leads to bankrupcy. Excessive smoking leads to emphysema.

I'm not ripping on you for posting this Libloather but this is a really stupid article.
38 posted on 11/29/2002 3:17:07 PM PST by Tailback
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To: CWRWinger
The only "withdrawal" is mental. You get used to being stoned all day or every night then you will miss it when you're dry....at least I did.

It was rather easy to quit voluntarily when I felt like that phase of limited responsibility in my life had passed but I can rememeber those dry summer months when last years harvest was dwindling and the next autumn one was not yet here and we would go on full alert to procure.
39 posted on 11/29/2002 3:19:01 PM PST by wardaddy
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To: Libloather
Could be extensive pot use accounts for the very slow learning curve of the Democrats.
40 posted on 11/29/2002 3:19:02 PM PST by WaterDragon
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To: Paul Atreides
LOL! Great photos and comment!
41 posted on 11/29/2002 3:19:52 PM PST by WaterDragon
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To: coloradan
That would make about the biggest bale I've ever seen X8.
42 posted on 11/29/2002 3:21:03 PM PST by wardaddy
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To: CWRWinger
Is it easier to quit than smoking

It most certainly is. I don't know about permanent brain damage though. In my era, the stuff was of poor quality by and large.

43 posted on 11/29/2002 3:23:34 PM PST by Torie
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To: wardaddy
Actually, incarceration provides a clarity unmatched by much outside of combat.

It's a pity that there are so few great works of literature, music, science, math and engineering to show for this clarity of which you speak, coming from the nation's enormous prison population.

44 posted on 11/29/2002 3:24:26 PM PST by coloradan
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To: Libloather
Well, back in my younger years, I would have qualified, at worst, as a very light smoker. A couple of tugs on the weekend was about all I ever found to be enjoyable. Any more than that and I just didn't feel in control.

But, those days are long gone. Too many responsibilities and no desire to lose my job or end up in the slammer.

45 posted on 11/29/2002 3:25:58 PM PST by meyer
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To: Libloather
Let me make this perfectly clear - I've never ONCE called Liberteens - mice...

Well it's a darn good thing you clarified that.
I think they could've refuted the following statement:

"In mice, excessive marijuana use might damage parts of the
brain and "knock out certain kinds of neurons," said Bolla."
More research needs to be done, of course,
but I'm pretty certain that liberteens don't have neurons.
46 posted on 11/29/2002 3:27:12 PM PST by Willie Green
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To: coloradan
That's simple Coloradan, those who go to prison are disproportionately inarticulate and uneducated and ill disciplined to begin with.

Clarity does not equate with creativity.
47 posted on 11/29/2002 3:29:18 PM PST by wardaddy
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To: Johnny Shear
I'm thinking the same thing. I think 13 joints a day would be enough for at least four or five potheads....
48 posted on 11/29/2002 3:31:49 PM PST by stands2reason
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To: Ramius
...People who smoked unusually large amounts of marijuana performed worse on tests of mental function than their peers who smoked less pot...

Yeah... What was the question again?

49 posted on 11/29/2002 3:35:20 PM PST by HairOfTheDog
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To: wardaddy
Yes indeed, there was decent pot around in the 70s my man...and lots of black hash as well and honey or red hash oil too. All very very stone-worthy. There was always lots of seedless Thai around as well.

I'm 38...Grew-up in Indiana. I was 12 in 1976. Obviously, I didn't really become "Aware" of the ins-and-outs of the dope scene until I got a little older but even then, the pot that was around was just OK...

All I remember was Columbian Gold and Mexican Brown. Both of which could be rolled into a cigarette sized doobie and give 4 people a light buzz...

Bags cost either 25 or 30 dollars. Quarter Pounds cost 90 dollars...You bought one, sold 3 ounces for 30 bucks apeice and got a free ounce for yourself.

Yeah, I heard about some good pot being around...Maybe I was too young to have one of the older guys share the "Good Stuff" with me...That wouldn't surprise me. But still, the pot that was around was leafy, brown and NASTY (As compared to what's around today).

As for Hash...It's odd...I've NEVER gotten a buzz on Hash. Don't know why.

I still remember the summer that pot went "Green" and EXPENSIVE!!! The town (And all of Indiana) was DRY!!! Dry for the entire summer. Then people started showing-up with this green stuff that cost TWENTY FIVE DOLLARS FOR A QUARTER OUNZE!!! That was the summer of 1981. Since then, Green (Stink, Skunk Weed) has been the norm. And it's stayed at approximately the same price...It's risen a bit. Maybe another price increase is in the works as we speak...I guess it's pretty dry out there (I keep a pretty good stock so I don't normally notice the dry periods anymore). I just paid $120.00 for a Quarter Ounze. It's pretty good but not THAT good!

Anyway...That's my Stoner Story.

And on this note...I just found out "What" I am (Politically). I'm a Broken Glass Republican but not a Te-Totaler...So, I've never really known what to call myself...Then I saw the post about "South Park Republicans". Fits me to a T!!!

50 posted on 11/29/2002 3:37:16 PM PST by Johnny Shear
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